Citation Impact
Citing Papers
Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K + Channel
2005 StandoutScienceNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis
2012
Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**
2021 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Active site modification of aldose reductase by nitric oxide donors
1997
Is chorismate mutase a prototypic entropy trap? - Activation parameters for the Bacillus subtilis enzyme
1996
“On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension
2005 StandoutNobel
Structure of a Voltage-Dependent K+ Channel β Subunit
1999 StandoutNobel
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
2000 StandoutNature
A ‘specificity’ pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil
1997
Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences
2008 Standout
Dynamic imine chemistry
2012 StandoutNobel
Computational Enzyme Design
2013 StandoutNobel
Modelling the catalytic reaction in human aldose reductase
1999
Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes
2011
Ion channels: From idea to reality
1999 StandoutNobel
A Highly Enantioselective Overman Rearrangement through Asymmetric Counteranion‐Directed Palladium Catalysis
2011 StandoutNobel
Structure of porcine aldehyde reductase holoenzyme
1995
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS
2000 StandoutNature
An Anion Binding Site in Human Aldose Reductase: Mechanistic Implications for the Binding of Citrate, Cacodylate, and Glucose 6-Phosphate
1994
Structural Basis of Inward Rectification
2002 StandoutNobel
Metabolic Engineering of Propanediol Pathways
1998
THE CRYSTAL STRUCTURE OF THE ALDOSE REDUCTASE NADPH BINARY COMPLEX
1992
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
A Catalytic Asymmetric 6 π Electrocyclization: Enantioselective Synthesis of 2‐Pyrazolines
2009 StandoutNobel
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
2002 StandoutNobel
Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å
2004 Standout
Perspectives on Oxygen Sensing
1999 StandoutNobel
Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3α-hydroxysteroid/dihydrodiol dehydrogenase
1997
Computational design of Candida boidinii xylose reductase for altered cofactor specificity
2009
Rewiring the Specificity of Two-Component Signal Transduction Systems
2008
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
New insight into the catalytic mechanism of chorismate mutases from structural studies
1995
Diversity in times of adversity: probabilistic strategies in microbial survival games
2005
Subunit interaction in catalysis. Some experimental and theoretical approaches with glyceraldehyde-3-phosphate dehydrogenase.
1982 StandoutNobel
Transient kinetic studies of malic enzyme
1978
Retro-Diels−Alder Femtosecond Reaction Dynamics
1996 StandoutNobel
Femtosecond Dynamics of Transition States and the Concept of Concertedness: Nitrogen Extrusion of Azomethane Reactions
1998 StandoutNobel
Functions of the gene products of Escherichia coli
1993
Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo–keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase
1998
Transition Structures of Hydrocarbon Pericyclic Reactions
1992 Standout
Mechanism of pigeon liver malic enzyme. Reactivity of class II sulfhydryl groups as conformational probe for the "half-of-the-sites" reactivity of the enzyme with bromopyruvate
1978
Der Mechanismus der Claisen‐Umlagerung – ein Déjà‐vu
1996
Structure of the Cytoplasmic β Subunit--T1 Assembly of Voltage-Dependent K + Channels
2000 StandoutScienceNobel
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
The crystal structure of the aldose reductase.NADPH binary complex.
1992
Medium Effects in Antibody-Catalyzed Reactions
1991 Science
Apparent NAC Effect in Chorismate Mutase Reflects Electrostatic Transition State Stabilization
2003 StandoutNobel
Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.
1993
Substrate conformational transitions in the active site of chorismate mutase: Their role in the catalytic mechanism
2001 Nobel
Conceptual Density Functional Theory
2003 Standout
Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
1997 StandoutScienceNobel
Calculation of transition state structures and kinetic isotope effects in the Claisen rearrangement of allyl vinyl ether and chorismic acid
1994
Oxidative Stress and Diabetic Complications
2010 Standout
PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light
1999
Ground- and Excited-State Reactions of Norbornene and Isomers: A CASSCF Study and Comparison with Femtosecond Experiments
1999 StandoutNobel
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
2013 StandoutNobel
Neural Science
2000 StandoutNobel
Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications.
1992
Catalytic mechanism of aldose reductase studied by the combined potentials of quantum mechanics and molecular mechanics
1998
Femtosecond β-cleavage dynamics: Observation of the diradical intermediate in the nonconcerted reactions of cyclic ethers
1998 StandoutNobel
The role of induced fit and conformational changes of enzymes in specificity and catalysis
1988
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
From Molecular Diversity to Catalysis: Lessons from the Immune System
1995 Science
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
The Mechanism of the Claisen Rearrangement: Déjà Vu All Over Again
1996
Catalytic site cooperativity of beef heart mitochondrial F1 adenosine triphosphatase. Correlations of initial velocity, bound intermediate, and oxygen exchange measurements with an alternating three-site model.
1982 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Kinetic studies of the malic enzyme of pigeon liver. "Half-of-the-sites" behavior of the enzyme tetramer in catalysis and substrate inhibition
1980
The Complete Genome Sequence of Escherichia coli K-12
1997 StandoutScience
The Halogen Bond
2016 Standout
Computer Simulation Studies of the Catalytic Mechanism of Human Aldose Reductase
2000 StandoutNobel
An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic Complications
1992 Science
Nucleus-Independent Chemical Shifts (NICS) as an Aromaticity Criterion
2005 Standout
Asymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy
2016 StandoutNobel
Claisen Rearrangement over the Past Nine Decades
2004
A Genomic Perspective on Protein Families
1997 StandoutScience
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
A Cope Rearrangement in the Reaction Catalyzed by Dimethylallyltryptophan Synthase?
2011
New Approach to 1,4‐Benzoxazin‐3‐ones by Electrochemical C−H Amination
2017
Routes to Catalysis: Structure of a Catalytic Antibody and Comparison with Its Natural Counterpart
1994 Science
The Interplay Between Chemistry and Biology in the Design of Enzymatic Catalysts
1988 Science
Works of Charles E. Grimshaw being referenced
Mechanism of Human Aldehyde Reductase: Characterization of the Active Site Pocket
1995
Oxidized Aldose Reductase:In VivoFactor, Notin VitroArtifact
1996
Human Aldose Reductase: Subtle Effects Revealed by Rapid Kinetic Studies of the C298A Mutant Enzyme
1995
Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Structure of the Y48H Mutant Enzyme
1994
Kinetic and structural effects of activation of bovine kidney aldose reductase
1989
Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose)polymerase inhibitors
2013
Mechanistic basis for nonlinear kinetics of aldehyde reduction catalyzed by aldose reductase
1990
Human Aldose Reductase: Rate Constants for a Mechanism Including Interconversion of Ternary Complexes by Recombinant Wild-Type Enzyme
1995
Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides
2010
Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism
2016
Human Aldose Reductase: pK of Tyrosine 48 Reveals the Preferred Ionization State for Catalysis and Inhibition
1995
Aldose reductase: model for a new paradigm of enzymic perfection in detoxification catalysts
1992
Immunoquantitation of aldose reductase in human tissues
1989
Synthesis of stereoselectively labeled [9-2H,3H]chorismate and the stereochemical course of 5-enolpyruvoylshikimate-3-phosphate synthetase
1984
Synergistic Kinetic Interactions between Components of the Phosphorelay Controlling Sporulation in Bacillus subtilis
1998
Characterization and nucleotide binding properties of a mutant dihydropteridine reductase containing an aspartate 37-isoleucine replacement.
1992
Catalytic effectiveness of human aldose reductase. Critical role of C-terminal domain.
1992
Determination of the rate-limiting steps for malic enzyme by the use of isotope effects and other kinetic studies
1977
Stereochemistry of the rearrangement of chorismate to prephenate: chorismate mutase involves a chair transition state
1984