Standout Papers
Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
A Method for Isolation of Intact, Translationally Active Ribonucleic Acid
1983
Nucleotide Sequence of a Human Immunoglobulin Cγ4 Gene
1981
Lymphocyte Activation Gene-3 (CD223) Regulates the Size of the Expanding T Cell Population Following Antigen Activation In Vivo
2004
The statistical distribution of nucleic acid similarities
1985
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
An enhancer deletion affects both H19 and Igf2 expression.
1995
The muscle regulatory gene, Myf-6, has a biphasic pattern of expression during early mouse development.
1991
Molecular clock of silent substitution: At least six-fold preponderance of silent changes in mitochondrial genes over those in nuclear genes
1982
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
1987 StandoutNature
Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death
1992
Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli
1989 StandoutNatureNobel
A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy
1998
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Disruption of imprinting caused by deletion of the H19 gene region in mice
1995 Nature
Structure of the human class I histocompatibility antigen, HLA-A2
1987 StandoutNature
Issues in searching molecular sequence databases
1994
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest
1989 StandoutNobel
Long-Term sensitization training in Aplysia leads to an increase in calreticulin, a major presynaptic calcium-binding protein
1992 StandoutNobel
Expression monitoring by hybridization to high-density oligonucleotide arrays
1996 Standout
Reshaping human antibodies for therapy
1988 StandoutNatureNobel
Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence
1997
MyoD or Myf-5 is required for the formation of skeletal muscle
1993 Standout
Location of enhancers is essential for the imprinting of H19 and Igf2 genes
1998 Nature
Functional sites of human class I MHC molecules: Paradigms a dozen?
1987
In vitro selection of RNA molecules that bind specific ligands
1990 StandoutNatureNobel
The immune response of Drosophila
2003 StandoutNatureNobel
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
Conformations of immunoglobulin hypervariable regions
1989 StandoutNatureNobel
Prediction of the Coding Sequences of Unidentified Human Genes. VI. The Coding Sequences of 80 New Genes (KIAA0201-KIAA0280) Deduced by Analysis of cDNA Clones from Cell Line KG-1 and Brain
1996
LAG-3 in Cancer Immunotherapy
2010
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
2008 Standout
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
1998
HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
1987 StandoutNature
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
2000 StandoutNature
Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3)
2002
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 StandoutNatureNobel
The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat
1991
The CD4‐related molecule, LAG‐3 (CD223), regulates the expansion of activated T cells
2003
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
The structural H19 gene is required for transgene imprinting
1996
Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells.
1995 StandoutNobel
Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
1999 Standout
Characterization of the major histocompatibility complex class II binding site on LAG-3 protein
1997
The Chronic Myelocytic Cell Line K562 Contains a Breakpoint in bcr and Produces a Chimeric bcr/c-abl Transcript
1986
A 5′ Differentially Methylated Sequence and the 3′-Flanking Region Are Necessary forH19Transgene Imprinting
1997
Linkage of the four gamma subclass heavy chain genes.
1981 StandoutNobel
Codon catalog usage is a genome strategy modulated for gene expressivity
1981
Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation.
1984
Cell type-specific activation of actin genes in the early amphibian embryo
1984 StandoutNatureNobel
Physical state and transcription of the cottontail rabbit papillomavirus genome in warts and transplantable VX2 and VX7 carcinomas of domestic rabbits
1984
Gene segments encoding transmembrane carboxyl termini of immunoglobulin γ chains
1981
DNA methylation and the regulation of globin gene expression
1983
The complete nucleotide sequence of mouse immunoglobulin γ2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer
1981 StandoutNobel
Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes
1985 Nature
New HLA DNA polymorphisms associated with autoimmune diseases
1986 Nature
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
1988 StandoutScienceNobel
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
1990 Standout
Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.
1983
Mapping of the class II region of the human major histocompatibility complex by pulsed-field gel electrophoresis
1986 Nature
Quality Control by DNA Repair
1999 StandoutScienceNobel
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure
1987 StandoutScience
CD3/TCR Complex-Associated Lymphocyte Activation Gene-3 Molecules Inhibit CD3/TCR Signaling
1998
Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.
1988
Methylation of the HLA-DR alpha gene is positively correlated with expression
1987
Gene organization of DC and DX subregions of the human major histocompatibility complex.
1985
Unusual evolutionary conservation and frequent DNA segment exchange in class I genes of the major histocompatibility complex.
1983
Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.
1984
Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.
1985
Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions.
1983 StandoutNobel
LAG-3, a novel lymphocyte activation gene closely related to CD4.
1990
Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene
1984
Multiple differences between the nucleic acid sequences of the IgG2aa and IgG2ab alleles of the mouse.
1981 Nobel
Direct Cloning and Sequence Analysis of Enzymatically Amplified Genomic Sequences
1986 Science
Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes.
1986
Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products.
1989
Long-term sensitization training in Aplysia leads to an increase in the expression of BiP, the major protein chaperon of the ER.
1992 StandoutNobel
Reversible silencing of enhancers by sequences derived from the human IFN-α promoter
1987
Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia
1985 StandoutScienceNobel
Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells.
1985
Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.
1983
Cloning and expression of an Aplysia K+ channel and comparison with native Aplysia K+ currents
1991
An analysis of incorrectly folded protein models
1984
Concerted evolution of the mouse immunoglobulin gamma chain genes.
1984 StandoutNobel
Ordering of mouse immunoglobulin heavy chain genes by molecular cloning
1981 StandoutNatureNobel
Linkage map of three HLA-DR beta-chain genes: evidence for a recent duplication event.
1985
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Diversity of germ-line immunoglobulin VH genes
1981 Nature
DR5-Associated DC molecules carry three different allospecificities
1985
The class II molecules of the human and murine major histocompatibility complex
1984
Heavy chain genes of rabbit IgG: isolation of a cDNA encoding gamma heavy chain and identification of two genomic C gamma genes.
1982
Domain association in immunoglobulin molecules
1985
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Purification and molecular cloning of an inducible gram-negative bacteria-binding protein from the silkworm, Bombyx mori.
1996
The galactan‐binding immunoglobulin Fab J539: An x‐ray diffraction study at 2.6‐Å resolution
1986
Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation.
1983
Evidence of a New Chimericbcr/c-ablmRNA in Patients with Chronic Myelocytic Leukemia and the Philadelphia Chromosome
1985
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Expression of the genes coding for the skeletal muscle and cardiac actins in the heart
1984
The T cell differentiation antigen Leu-2/T8 is homologous to immunoglobulin and T cell receptor variable regions
1985
Inactivation of p53 gene expression by an insertion of Moloney murine leukemia virus-like DNA sequences.
1984
Molecular diversity of HLA-DR4 haplotypes.
1986
Independent Modes of Natural Killing Distinguished in Mice Lacking Lag3
1996 Science
Phosphocholine binding immunoglobulin Fab McPC603
1986
MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos.
1989 StandoutNobel
Replacing the complementarity-determining regions in a human antibody with those from a mouse
1986 StandoutNatureNobel
Identification of a polymorphic variant associated with HLA-DQw3 and characterized by specific restriction sites within the DQ beta-chain gene.
1985
Cutting Edge: Molecular Analysis of the Negative Regulatory Function of Lymphocyte Activation Gene-3
2002
Genomic sequencing.
1984 Standout
A gene sequence expressed only in undifferentiated EC, EK cells and testes.
1984 StandoutNobel
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Structural organization of the DR subregion of the human major histocompatibility complex.
1985
The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes.
1982
Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes
1986 StandoutNatureNobel
Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
1985 StandoutNatureNobel
Somatic generation of antibody diversity
1983 StandoutNatureNobel
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.
1986 StandoutNobel
Mode of enzyme-bound poly(ADP-ribose) synthesis and histone modification by reconstituted poly(ADP-ribose) polymerase-DNA-cellulose complex.
1981
Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.
1993 StandoutNobel
HLA-DR2-associated Dw subtypes correlate with RFLP clusters: most DR2 IDDM patients belong to one of these clusters
1986
DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.
1985
Molecular distinction between fetal and adult forms of muscle acetylcholine receptor
1986 StandoutNatureNobel
A comprehensive set of sequence analysis programs for the VAX
1984 StandoutNobel
Papilloma virus-induced tumors contain a virus-specific transcript
1982
Diversity of G Proteins in Signal Transduction
1991 StandoutScience
Nucleotide sequence of an HLA-DQ alpha chain derived from a DRw9 cell line: genetic and evolutionary implications.
1985
Gene conversion and polymorphism: Generation of mouse immunoglobulin γ2a chain alleles by differential gene conversion by γ2b chain gene
1983
Thetwistgene: isolation of a Drosophila zygotle gene necessary for the establishment of dorsoventral pattern
1987
Negative Regulation of T Cell Homeostasis by Lymphocyte Activation Gene-3 (CD223)
2005
A Novel Method for the Detection of Polymorphic Restriction Sites by Cleavage of Oligonucleotide Probes: Application to Sickle-Cell Anemia
1985
The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region
1983 Nature
Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12.
1990
Works of Charles Auffray being referenced
Finding new genes faster than ever
1993
Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
1988 StandoutNobel
Mouse immunoglobulin A: Nucleotide sequence of the structural gene for the α heavy chain derived from cloned cDNAs
1981
Mouse immunoglobulin genes: a bacterial plasmid containing the entire coding sequence for a pre-γ 2a heavy chain
1980
A program for prediction of protein secondary structure from nucleotide sequence data: application to histocompatibility antigens
1984
The Genexpress Index: a resource for gene discovery and the genic map of the human genome.
1995
Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes
1984 Nature
Mouse heavy chain variable regions: nucleotide sequence of a germ-line VHgene segment
1981
Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA
1980 Standout
Novel gene transcripts preferentially expressed in human muscles revealed by quantitative hybridization of a high density cDNA array.
1996
Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor.
1982
Correlation between D region structure and antigen-binding specificity: evidences from the comparison of closely related immunoglobulin VH sequences.
1982
The amino acid sequence and gene organization of the heavy chain of the HLA-DR antigen: homology to immunoglobulins.
1982
A minimum of four human class II α-chain genes are encoded in the HLA region of chromosome 6
1983 Nature
Polymorphism and complexity of the human DC and murine I-A alpha chain genes.
1983
Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex.
1989
Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic family.
1981
Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens.
1992
Nucleotide sequence of a cloned cDNA corresponding to secreted μ chain of mouse immunoglobulin
1980
SB subregion of the human major histocompatibility complex: gene organization, allelic polymorphism and expression in transformed cells.
1985
Structure of the constant and 3′ untranslated regions of the murine Balb/c γ2a heavy chain messenger RNA
1980
Nucleotide sequence of constant and 3' untranslated regions of a kappa immunoglobulin light chain mRNA of a homozygous b4 rabbit.
1981
Speculations on Sequence Homologies between the fibronectin cell-attachment site, major histocompatibility antigens, and a putative AIDS virus polypeptide
1986
Rat immunoglobulin delta heavy chain gene: nucleotide sequence derived from cloned cDNA
1982