Standout Papers
Citation Impact
Citing Papers
Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K + Channel
2005 StandoutScienceNobel
Voltage sensor conformations in the open and closed states in rosetta structural models of K + channels
2006 StandoutNobel
Bile acid transporters
2009
Tarantula toxins interacting with voltage sensors in potassium channels
2006
The open pore conformation of potassium channels
2002 StandoutNatureNobel
Relative Unidirectional Translation in an Artificial Molecular Assembly Fueled by Light
2013 StandoutNobel
Pathogenesis of type 2 diabetes mellitus
2004
Energetics of Pore Opening in a Voltage-Gated K+ Channel
2002 StandoutNobel
Structure of a Voltage-Dependent K+ Channel β Subunit
1999 StandoutNobel
Diffusion-controlled binding of a peptide neurotoxin to its potassium channel receptor
1990
Inhibition of Renal Glucose Reabsorption: A Novel Strategy for Achieving Glucose Control in Type 2 Diabetes Mellitus
2008
Functional analysis of an archaebacterial voltage-dependent K+ channel
2003 StandoutNatureNobel
Influence of protein surface charge on the bimolecular kinetics of a potassium channel peptide inhibitor
1993 StandoutNobel
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
X-ray structure of a voltage-dependent K+ channel
2003 StandoutNatureNobel
Charybdotoxin block of Shaker K+ channels suggests that different types of K+ channels share common structural features
1988 StandoutNobel
Crystal structure and mechanism of a calcium-gated potassium channel
2002 StandoutNatureNobel
Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus
1998 StandoutNobel
Interaction of charybdotoxin with permeant ions inside the pore of a K+ channel
1992
Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution
2001 StandoutNatureNobel
Role of surface electrostatics in the operation of a high-conductance calcium-activated potassium channel
1989 StandoutNobel
Mapping function to structure in a channel-blocking peptide: electrostatic mutants of charybdotoxin
1992
Intimations of potassium channel structure from a complete functional map of the molecular surface of charybdotoxin
1994
Mechanism of iberiotoxin block of the large-conductance calcium-activated potassium channel from bovine aortic smooth muscle
1992
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Transfer of the scorpion toxin receptor to an insensitive potassium channel
1994
Energetic optimization of ion conduction rate by the K+ selectivity filter
2001 StandoutNatureNobel
Mapping the receptor site for charybdotoxin, a pore-blocking potassium channel inhibitor
1990 StandoutNobel
Ca2+‐ and thromboxane‐dependent distribution of MaxiK channels in cultured astrocytes: From microtubules to the plasma membrane
2009
Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+channel
1994 StandoutNatureNobel
Charybdotoxin, dendrotoxin and mast cell degranulating peptide block the voltage-activated K+ current of fibroblast cells stably transfected with NGK1 (Kvl.2) K+ channel complementary DNA
1992
Glial and neuronal control of brain blood flow
2010 StandoutNature
Purification and Characterization of Three Inhibitors of Voltage-Dependent K+ Channels from Leiurus Quinquestriatus var. Hebraeus Venom
1994 StandoutNobel
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
The charybdotoxin receptor of a Shaker K+ channel: Peptide and channel residues mediating molecular recognition
1994
Voltage gating of ion channels
1994
Identification of a Gene Encoding a Hyperpolarization-Activated Pacemaker Channel of Brain
1998 StandoutNobel
Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels
1993 StandoutNobel
Competition for block of a Ca2+-activated K+ channel by charybdotoxin and tetraethylammonium
1988
Synthetic charybdotoxin-iberiotoxin chimeric peptides define toxin binding sites on calcium-activated and voltage-dependent potassium channels
1993
Analysis of the blocking activity of charybdotoxin homologs and iodinated derivatives against Ca2+-Activated K+ channels
1989
The principle of gating charge movement in a voltage-dependent K+ channel
2003 StandoutNatureNobel
Mapping the Receptor Site for Hanatoxin, a Gating Modifier of Voltage-Dependent K+ Channels
1997
Spatial Localization of the K+ Channel Selectivity Filter by Mutant Cycle–Based Structure Analysis
1996
Use of toxins to study potassium channels
1991
Determination of the three-dimensional structure of iberiotoxin in solution by proton nuclear magnetic resonance spectroscopy
1992
Hanatoxin Modifies the Gating of a Voltage-Dependent K+ Channel through Multiple Binding Sites
1997 StandoutNobel
Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release
1993
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Determination of the subunit stoichiometry of a voltage-activated potassium channel
1991 StandoutNatureNobel
Functional modification of calcium-activated potassium channel by trimethyloxonium
1989 StandoutNobel
The charybdotoxin family of K+ channel-blocking peptides
1995
An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantula
1995 StandoutNobel
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
2015 Standout
Mechanism of charybdotoxin block of a voltage-gated K+ channel
1993
From Foe to Friend: Using Animal Toxins to Investigate Ion Channel Function
2014
An emerging pharmacology of peptide toxins targeted against potassium channels
1988
Purification and reconstitution of the high-conductance, calcium-activated potassium channel from tracheal smooth muscle.
1994
1990: Annus Mirabilis of Potassium Channels
1991 Science
Mutations Affecting Internal TEA Blockade Identify the Probable Pore-Forming Region of a K + Channel
1991 StandoutScienceNobel
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
2009 Standout
Mutant Potassium Channels with Altered Binding of Charybdotoxin, a Pore-Blocking Peptide Inhibitor
1989 StandoutScienceNobel
Structure of the Cytoplasmic β Subunit--T1 Assembly of Voltage-Dependent K + Channels
2000 StandoutScienceNobel
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
Characterization of High Affinity Binding Sites for Charybdotoxin in Sarcolemmal Membranes from Bovine Aortic Smooth Muscle
1989
Functional Stoichiometry of Shaker Potassium Channel Inactivation
1993 StandoutScienceNobel
Mechanism of charybdotoxin block of the high-conductance, Ca2+-activated K+ channel.
1988 StandoutNobel
The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity
1998 StandoutScienceNobel
Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus.
1990
SGLT-2 inhibitors and cardiovascular risk: Proposed pathways and review of ongoing outcome trials
2015
Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences
2015
Energetically Demanding Transport in a Supramolecular Assembly
2014 StandoutNobel
Biology of Human Sodium Glucose Transporters
2011
Semisynthesis and Folding of the Potassium Channel KcsA
2002 StandoutNobel
A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K + Channels
1992 StandoutScienceNobel
Molecular Surface of Tarantula Toxins Interacting with Voltage Sensors in Kv Channels
2004
Single Streptomyces lividans K+ Channels
1999
Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels
1998 StandoutScienceNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Design, synthesis, and functional expression of a gene for charybdotoxin, a peptide blocker of K+ channels.
1991
Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca(2+)-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom.
1992
Revealing the Architecture of a K + Channel Pore Through Mutant Cycles with a Peptide Inhibitor
1995 StandoutScienceNobel
Mutations Affecting Tea Blockade and Ion Permeation in Voltage-activated K + Channels
1990 StandoutScienceNobel
Empagliflozin improves glycaemic and weight control as add‐on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24‐week, randomized, placebo‐controlled trial
2013
Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer
1994 StandoutScienceNobel
Structural Rearrangements Underlying K + -Channel Activation Gating
1999 Science
Selective blockers of voltage-gated K+ channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin.
1992
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides.
1993
Works of Chari D. Smith being referenced
Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94
2002
Inhibitor Binding in the Human Renal Low- and High-Affinity Na+/Glucose Cotransporters
2007
Baculovirus-mediated expression of the Na+/glucose cotransporter in Sf9 cells
1992
Glucose Transporters in Human Renal Proximal Tubular Cells Isolated From the Urine of Patients With Non–Insulin-Dependent Diabetes
2005
Charybdotoxin block of single Ca2+-activated K+ channels. Effects of channel gating, voltage, and ionic strength.
1988 StandoutNobel
Intestinal and renal Na+/glucose cotransporters share common structures
1991