Standout Papers
Citation Impact
Citing Papers
Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
2009 StandoutNobel
Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow
2012
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Identification of O-Linked N-Acetylglucosamine (O-GlcNAc)-modified Osteoblast Proteins by Electron Transfer Dissociation Tandem Mass Spectrometry Reveals Proteins Critical for Bone Formation
2013
Hedgehog: functions and mechanisms
2008 Standout
Cancer to bone: a fatal attraction
2011 Standout
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Increased skeletal VEGF enhances β‐catenin activity and results in excessively ossified bones
2009
The bone marrow at the crossroads of blood and immunity
2011
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Advances in osteoclast biology: old findings and new insights from mouse models
2011
Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
2009
Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes
2013
Building strong bones: molecular regulation of the osteoblast lineage
2011
Identification of a clonally expanding haematopoietic compartment in bone marrow
2012
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey
2008 StandoutNobel
Portrait of PTEN: Messages from mutant mice
2008 StandoutNobel
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Suppression of bone formation by osteoclastic expression of semaphorin 4D
2011 Standout
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Biology of HIF-1α
2008
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
Patched1 Haploinsufficiency Increases Adult Bone Mass and Modulates Gli3 Repressor Activity
2008
Oxygen homeostasis
2009 StandoutNobel
Organization of four mouse lambda light chain immunoglobulin genes.
1981 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4
2010
Linkage of the four gamma subclass heavy chain genes.
1981 StandoutNobel
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene
1983 StandoutNobel
Sequences of mouse immunoglobulin light chain genes before and after somatic changes
1978 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes
1981 StandoutNobel
Structure of a rearranged gamma 1 chain gene and its implication to immunoglobulin class-switch mechanism.
1981 StandoutNobel
Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes.
1984 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes
1981 StandoutNatureNobel
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes
1980 StandoutNatureNobel
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.
1980 StandoutNobel
Deletion of immunoglobulin heavy chain genes from expressed allelic chromosome
1980 StandoutNatureNobel
Guidelines for assessment of bone microstructure in rodents using micro–computed tomography
2010 Standout
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Exon shuffling generates an immunoglobulin heavy chain gene.
1980 StandoutNobel
A complete immunoglobulin gene is created by somatic recombination
1978
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments
1979 StandoutNatureNobel
Immunoglobulin Gene Rearrangement in Immature B Cells
1980 StandoutScienceNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
DNA sequences of the joining regions of mouse lambda light chain immunoglobulin genes.
1982 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes
1981 StandoutNatureNobel
Hypoxia‐inducible factor regulates osteoclast‐mediated bone resorption: role of angiopoietin‐like 4
2010
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Somatic generation of antibody diversity
1983 StandoutNatureNobel
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Inactivation of Pten in Osteo-Chondroprogenitor Cells Leads to Epiphyseal Growth Plate Abnormalities and Skeletal Overgrowth
2007
Sequences at the somatic recombination sites of immunoglobulin light-chain genes
1979 StandoutNatureNobel
Chemical Glycoproteomics
2016 StandoutNobel
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Restricted association of V and J-C gene segments for mouse lambda chains.
1984 StandoutNobel
Works of Chao Wan being referenced
Lifelong accumulation of bone in mice lacking Pten in osteoblasts
2007
Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration
2008
Hypoxia‐inducible factors 1α and 2α exert both distinct and overlapping functions in long bone development
2009
The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development
2007
Allogenic peripheral blood derived mesenchymal stem cells (MSCs) enhance bone regeneration in rabbit ulna critical-sized bone defect model
2006
TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
2009 Standout
Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice
2009
Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition
2010
Hedgehog Signaling in Mature Osteoblasts Regulates Bone Formation and Resorption by Controlling PTHrP and RANKL Expression
2008
Bone Formation During Distraction Osteogenesis Is Dependent on Both VEGFR1 and VEGFR2 Signaling
2008