Citation Impact
Citing Papers
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility
2021 StandoutNobel
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
The Ensembl Variant Effect Predictor
2016 Standout
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Regulatory elements of Caenorhabditis elegans ribosomal protein genes
2012
BLMP-1/Blimp-1 Regulates the Spatiotemporal Cell Migration Pattern in C. elegans
2014
Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs
2013
Genome-wide prediction of disease variant effects with a deep protein language model
2023
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
2018
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
2016 Standout
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
2017
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
Regulation of Synaptic nlg-1/Neuroligin Abundance by the skn-1/Nrf Stress Response Pathway Protects against Oxidative Stress
2014
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants
2021
Locus Reference Genomic: reference sequences for the reporting of clinically relevant sequence variants
2013
Genetic effects on gene expression across human tissues
2017 StandoutNature
Accurate classification of BRCA1 variants with saturation genome editing
2018 Nature
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
2013 StandoutNobel
Predicting the clinical impact of human mutation with deep neural networks
2018
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
2019 Standout
Roles of the Developmental Regulator unc-62/Homothorax in Limiting Longevity in Caenorhabditis elegans
2013
Hallmarks of aging: An expanding universe
2023 Standout
Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf
2013
PQM-1 Complements DAF-16 as a Key Transcriptional Regulator of DAF-2-Mediated Development and Longevity
2013
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Somatic genomic changes in single Alzheimer’s disease neurons
2022 Nature
A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport
2016 StandoutNobel
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
ClinVar: public archive of relationships among sequence variation and human phenotype
2013 Standout
Human 5′ UTR design and variant effect prediction from a massively parallel translation assay
2019
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Base editing: precision chemistry on the genome and transcriptome of living cells
2018
Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors
2019
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Metazoan MicroRNAs
2018 Standout
Comparison of Computed Tomographic Angiography with Digital Subtraction Angiography in the Diagnosis of Cerebral Aneurysms: A Meta-analysis
2003
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
2016 Standout
EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan
2011
The impact of rare variation on gene expression across tissues
2017 Nature
Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans
2013 StandoutNobel
SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans
2015
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO
2012
EMT: 2016
2016 Standout
Mutation effects predicted from sequence co-variation
2017
The −319C/+49G/CT60G Haplotype of CTLA-4 Gene Confers Susceptibility to Rheumatoid Arthritis in Mexican Population
2013
Regulating distal tip cell migration in space and time
2017
Subarachnoid haemorrhage
2007 Standout
Specific SKN-1/Nrf Stress Responses to Perturbations in Translation Elongation and Proteasome Activity
2011
The Hallmarks of Aging
2013 Standout
Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing
2018 Standout
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Osteoporotic bone of miR-150-deficient mice: Possibly due to low serum OPG-mediated osteoclast activation
2015
Improving the Sequence Ontology terminology for genomic variant annotation
2015
The impact of retrotransposons on human genome evolution
2009
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase
2020
The C. elegans SNAPc Component SNPC-4 Coats piRNA Domains and Is Globally Required for piRNA Abundance
2014
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans
2011
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer
2013
Transposable elements reveal a stem cell-specific class of long noncoding RNAs
2012
Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
2015
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
2019 StandoutNobel
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
State-of-the-science of endocrine disrupting chemicals, 2012
2012
Analysis and minimization of cellular RNA editing by DNA adenine base editors
2019
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
2016 StandoutNobel
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Prioritizing genes for systematic variant effect mapping
2020
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Gene: a gene-centered information resource at NCBI
2014
De novo design of small beta barrel proteins
2023 StandoutNobel
The Halogen Bond
2016 Standout
A Deep Neural Network for Predicting and Engineering Alternative Polyadenylation
2019
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Works of Chao Chen being referenced
Removing Batch Effects in Analysis of Expression Microarray Data: An Evaluation of Six Batch Adjustment Methods
2011
Using Alu Elements as Polyadenylation Sites: A Case of Retroposon Exaptation
2008
MicroRNAs and their roles in osteoclast differentiation
2011
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans
2010
Exposure in utero to 2,2′,3,3′,4,6′-hexachlorobiphenyl (PCB 132) impairs sperm function and alters testicular apoptosis-related gene expression in rat offspring
2007
dbVar and DGVa: public archives for genomic structural variation
2012
ClinVar: public archive of interpretations of clinically relevant variants
2015 Standout
Absence of coding somatic single nucleotide variants within well-known candidate genes in late-onset sporadic Alzheimer's Disease based on the analysis of multi-omics data
2021
[Association of CTLA-4 + 49A/G and CT60 gene polymorphism with type 1 diabetes and thyroid autoimmunity].
2009
Detection and assessment of circle of Willis aneurysms in acute subarachnoid hemorrhage with three-dimensional computed tomographic angiography: correlation with digital substraction angiography findings.
1999