Standout Papers
Citation Impact
Citing Papers
Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II–associated methyltransferase
2018 Science
A fast, lock-free approach for efficient parallel counting of occurrences of k -mers
2011 Standout
Single-base mapping of m 6 A by an antibody-independent method
2019
RNA modifications modulate gene expression during development
2018 Science
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
2016 StandoutNobel
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
The RNA m 6 A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence
2017
HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
2015
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal
2018
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
m6A mRNA methylation regulates CTNNB1 to promote the proliferation of hepatoblastoma
2019
An association study of the m6A genes with major depressive disorder in Chinese Han population
2015
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1
2017
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
2017
N 6 -methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
2020 Science
The Biogenesis, Functions, and Challenges of Circular RNAs
2018 Standout
N6-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics
2016
Distinguishing RNA modifications from noise in epitranscriptome maps
2018
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
2017
Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance
2017
Mechanisms of hepatic stellate cell activation
2017 Standout
A brave new world of RNA-binding proteins
2018
Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis
2019
Coordination of m 6 A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming
2015
YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex
2016
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
The influence of dietary and nondietary calcium supplementation on blood pressure An updated metaanalysis of randomized controlled trials
1999
N6-Methylated Adenosine in RNA: From Bacteria to Humans
2015
Evolution of transcript modification by N6-methyladenosine in primates
2017
Post-transcriptional gene regulation by mRNA modifications
2016 Standout
Cracking the epitranscriptome
2016
A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors
2018
Evidence for the Relationship of Calcium to Blood Pressure*
2009
m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition
2017 Nature
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment
2017 StandoutNobel
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3
2019
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner
2019
RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding
2017
Long Noncoding RNAs in Cancer Pathways
2016 Standout
The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
2016
Dynamics of Human and Viral RNA Methylation during Zika Virus Infection
2016
m6A-LAIC-seq reveals the census and complexity of the m6A epitranscriptome
2016
Structural imprints in vivo decode RNA regulatory mechanisms
2015 Nature
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
2016 StandoutNobel
Hepatocellular carcinoma
2021 Standout
Gene regulation in the immune system by long noncoding RNAs
2017
Maternal and child undernutrition and overweight in low-income and middle-income countries
2013 Standout
Maintenance of redox homeostasis by hypoxia-inducible factors
2017 StandoutNobel
Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development
2018
Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex
2019
Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
2017
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
2017
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
2018 Standout
Epitranscriptomic influences on development and disease
2017
m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program
2017
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
2007 Guidelines for the Management of Arterial Hypertension
2007 Standout
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation
2015
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
RNA structure maps across mammalian cellular compartments
2019
N6-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding
2015
Duplication count distributions in DNA sequences
2008
Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
2018 Standout
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
2018
N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
2018
Widespread occurrence ofN6-methyladenosine in bacterial mRNA
2015
N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation
2018
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
2017
Pre-eclampsia
2010 Standout
Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
2019 Standout
Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy
2018 StandoutNobel
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
2018
Unique features of long non-coding RNA biogenesis and function
2015 Standout
m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways
2017 Nature
5′ UTR m6A Promotes Cap-Independent Translation
2015 Standout
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
2017
N6-Methyladenosine Modification Controls Circular RNA Immunity
2019
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
2017 Nature
A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
2015
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
2020 Standout
The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network
2019
The biogenesis, biology and characterization of circular RNAs
2019 Standout
Mechanistic insights in X-chromosome inactivation
2017
An RNA-centric dissection of host complexes controlling flavivirus infection
2019 StandoutNobel
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA
2017
Regulation of m6A Transcripts by the 3ʹ→5ʹ RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline
2017
Reading, writing and erasing mRNA methylation
2019 Standout
Supplemental Calcium and Risk Reduction of Hypertension, Pregnancy-Induced Hypertension, and Preeclampsia: An Evidence-Based Review by the US Food and Drug Administration
2008
Effects of Dietary Calcium Supplementation on Blood Pressure
1996
Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
2017
The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency
2018 Nature
Probing RNA Modification Status at Single-Nucleotide Resolution in Total RNA
2015
Reading m6A in the Transcriptome: m6A-Binding Proteins
2017
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis
2017
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
N6-methyladenosine marks primary microRNAs for processing
2015 Nature
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells
2016
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
2015 StandoutNature
The role of MicroRNAs in human cancer
2016 Standout
Human METTL16 is a N 6 ‐methyladenosine (m 6 A) methyltransferase that targets pre‐mRNAs and various non‐coding RNAs
2017
Rethinking m6A Readers, Writers, and Erasers
2017
From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing
2015 Nobel
Detection ofN6-methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease
2017
N 6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential
2018
Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
2012 Standout
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
2016 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells
2017
Systematic Reviews: Synthesis of Best Evidence for Clinical Decisions
1997 Standout
2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension
2003 Standout
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K‐Akt signaling in gastric cancer
2019
RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
2017
Effects of supplementation with multivitamin and mineral on blood pressure and C-reactive protein in obese Chinese women with increased cardiovascular disease risk.
2009
Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification
2015
A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA
2022 StandoutNobel
Nutritional composition of five cultivars of chinese jujube
2006 Standout
m6A modulates neuronal functions and sex determination in Drosophila
2016 Nature
YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
2017
METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N 6‐methyladenosine‐dependent primary MicroRNA processing
2016
Structural insights into the molecular mechanism of the m6A writer complex
2016
Tunable protein synthesis by transcript isoforms in human cells
2016 StandoutNobel
The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline
2017
Cross-talk among writers, readers, and erasers of m 6 A regulates cancer growth and progression
2018
N6-methyladenosine–encoded epitranscriptomics
2016
Works of Chan Zhou being referenced
Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins
2016
m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
2014 Standout
Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs
2017
Clinical Observation of Treatment of Hypertension With Calcium
1994
Exact Distribution of the Occurrence Number for K-tuples Over an Alphabet of Non-Equal Probability Letters
2004