Citation Impact
Citing Papers
Distinct Phosphorylation Sites on the β 2 -Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin
2011 StandoutNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
β-Arrestin-mediated Signaling Regulates Protein Synthesis
2008 StandoutNobel
Pharmacological Onomastics: What's in a name?
2007
Nanobody stabilization of G protein-coupled receptor conformational states
2011 StandoutNobel
Signalling bias in new drug discovery: detection, quantification and therapeutic impact
2012
Kappa opioids promote the proliferation of astrocytes via Gβγ and β‐arrestin 2‐dependent MAPK‐mediated pathways
2008
Cellular assays as portals to seven-transmembrane receptor-based drug discovery
2009
β-Arrestin-biased Agonism at the β2-Adrenergic Receptor
2007 StandoutNobel
G protein-independent cell-based assays for drug discovery on seven-transmembrane receptors
2008
Physiological and pharmacological implications of beta-arrestin regulation
2008
Serotonin, But Not N -Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo
2010
Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer
2009 StandoutNobel
Ligand-Specific Interactions Modulate Kinetic, Energetic, and Mechanical Properties of the Human β2 Adrenergic Receptor
2012 StandoutNobel
Crystallizing Thinking about the β2-Adrenergic Receptor
2008 StandoutNobel
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Quantifying Ligand Bias at Seven-Transmembrane Receptors
2011 StandoutNobel
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Psychedelics
2016 Standout
Structure-based discovery of opioid analgesics with reduced side effects
2016 NatureNobel
Molecular Dynamics Simulation for All
2018 Standout
Serotonin receptor signaling and regulation via β-arrestins
2010
Biased Agonist Pharmacochaperones of the AVP V2 Receptor May Treat Congenital Nephrogenic Diabetes Insipidus
2009
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
Structure-based drug screening for G-protein-coupled receptors
2012 StandoutNobel
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
Synthesis and biological evaluation of C-2 halogenated analogs of salvinorin A
2010
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
2011 StandoutNobel
A new era of GPCR structural and chemical biology
2012 StandoutNobel
Multiple ligand-specific conformations of the β2-adrenergic receptor
2011 StandoutNobel
Short synthesis of a novel class of salvinorin A analogs with hemiacetalic structure
2008
How were new medicines discovered?
2011 Standout
Teaching old receptors new tricks: biasing seven-transmembrane receptors
2010 StandoutNobel
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Functional selectivity of GPCR signaling in animals
2013
The neural basis of psychedelic action
2022 Standout
Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery
2010
β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice
2009 StandoutNobel
Structural insights into adrenergic receptor function and pharmacology
2011 StandoutNobel
Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6
2009
Structure Determination and Total Synthesis of (+)‐16‐Hydroxy‐16,22‐dihydroapparicine
2013 StandoutNobel
Total synthesis of the Daphniphyllum alkaloid daphenylline
2013
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Functional Selectivity and Biased Receptor Signaling
2010
β-arrestin-mediated receptor trafficking and signal transduction
2011 StandoutNobel
Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors
2007
Macrophages as tools and targets in cancer therapy
2022
Impact of high-throughput screening in biomedical research
2011 Standout
Constituents from Salvia Species and Their Biological Activities
2012 Standout
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
2008 StandoutNobel
The first total synthesis and reassignment of the relative stereochemistry of 16-hydroxy-16,22-dihydroapparicine
2012 StandoutNobel
Mining the Biodiversity of Plants: A Revolution in the Making
2012 Science
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
2015 Standout
Azine Activation via Silylium Catalysis
2021 StandoutNobel
Computational design of environmental sensors for the potent opioid fentanyl
2017 StandoutNobel
A crystal clear view of the β2-adrenergic receptor
2008 StandoutNobel
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
2017 StandoutNobel
β-Arrestin-biased ligands at seven-transmembrane receptors
2007 StandoutNobel
Conformational Dynamics of Single G Protein-Coupled Receptors in Solution
2011 StandoutNobel
A β-Arrestin–Biased Agonist of the Parathyroid Hormone Receptor (PTH1R) Promotes Bone Formation Independent of G Protein Activation
2009 StandoutNobel
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Flower power
2011
Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo
2008
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Works of Chad E. Groer being referenced
Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain
2011
Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation
2011
Functional Selectivity at the μ-Opioid Receptor: Implications for Understanding Opioid Analgesia and Tolerance
2011
Synthesis and κ-Opioid Receptor Activity of Furan-Substituted Salvinorin A Analogues
2014
Functional Selectivity of 6′-Guanidinonaltrindole (6′-GNTI) at κ-Opioid Receptors in Striatal Neurons
2013
An Opioid Agonist that Does Not Induce μ-Opioid Receptor—Arrestin Interactions or Receptor Internalization
2006
Formulation and preclinical evaluation of a toll-like receptor 7/8 agonist as an anti-tumoral immunomodulator
2019
Herkinorin Analogues with Differential β-Arrestin-2 Interactions
2008