Citation Impact
Citing Papers
DNA Damage–Specific Control of Cell Death by Cryptochrome in p53-Mutant Ras–Transformed Cells
2012 StandoutNobel
Circadian oscillation of nucleotide excision repair in mammalian brain
2009 StandoutNobel
A novel trans-platinum coordination complex possessing in vitro and in vivo antitumor activity.
1994
BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma
2000
A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours
2011
Biochemical and Molecular Mechanisms of Cisplatin Resistance
2002
Mechanisms of drug resistance to the platinum complex ZD0473 in ovarian cancer cell lines
2000
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
2011 Standout
Mesoporous silica nanoparticles in biomedical applications
2012 StandoutNobel
Strand-specific Mismatch Repair in Mammalian Cells
1997 StandoutNobel
Cisplatin: mode of cytotoxic action and molecular basis of resistance
2003 Standout
Flow cytometry in analysis of cell cycle and apoptosis
2001
Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies
2008 Standout
cis-Diamminedichloroplatinum(II)-induced cell death through apoptosis in sensitive and resistant human ovarian carcinoma cell lines
1996
Increased nucleotide excision repair in cisplatin-resistant ovarian cancer cells
2000
Phase I and pharmacokinetic study of an oral platinum complex given daily for 5 days in patients with cancer.
1997
Acquisition of platinum drug resistance and platinum cross resistance patterns in a panel of human ovarian carcinoma xenografts
1993
The development of platinum compounds and their possible combination
2006
Reduced drug accumulation as a major mechanism of acquired resistance to cisplatin in a human ovarian carcinoma cell line: circumvention studies using novel platinum (II) and (IV) ammine/amine complexes
1992
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
The resurgence of platinum-based cancer chemotherapy
2007 Standout
In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473
1998
Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines
1994
Fluorescence-activated cell sorting of transfected cells
1997 StandoutNobel
HSP90 and the chaperoning of cancer
2005 Standout
Platinum complexes with imino ethers or cyclic ligands mimicking imino ethers: synthesis, in vitro antitumour activity, and DNA interaction properties
2004
Anti-proliferative activity and mechanism of action of titanocene dichloride
1998
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance
2006
Apoptosis induction and inhibition of H-ras overexpression by novel trans-[PtCl2(isopropylamine)(amine′)] complexes1This work was presented at the 8th International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, held in Oxford, UK, 28–31 March 1999.1
1999
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
Molecular mechanisms of cisplatin resistance
2011 Standout
Analysis of apoptosis by propidium iodide staining and flow cytometry
2006 Standout
Human Ku Autoantigen Binds Cisplatin-damaged DNA but Fails to Stimulate Human DNA-activated Protein Kinase
1996
Cellular response to oxidative stress: Signaling for suicide and survival*
2002 Standout
An update on satraplatin: the first orally available platinum anticancer drug
2000
Intracellular metabolism of the orally active platinum drug JM216: influence of glutathione levels
1996
Upstream and downstream of mTOR
2004 Standout
Analysis of apoptosis by laser scanning cytometry
1999
Preclinical Perspectives on Platinum Resistance
2000
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
2015 Standout
Chapter 24 Difficulties and pitfalls in analysis of apoptosis
2001
Cycloplatam: A novel platinum compound exhibiting a different spectrum of anti-tumour activity to cisplatin
1995
Cellular processing of platinum anticancer drugs
2005 Standout
Cell-cycle arrests and p53 accumulation induced by geldanamycin in human ovarian tumour cells
1996
Association of high molecular weight DNA fragmentation with apoptotic or non‐apoptotic cell death induced by calcium ionophore
1995
Mind the gap: A survey of how cancer drug carriers are susceptible to the gap between research and practice
2013
Oxaliplatin for the treatment of cisplatin-resistant cancer: A systematic review
2007
Cell death beyond apoptosis
2000
Bioorganometallic chemistry—from teaching paradigms to medicinal applications
2008 Standout
JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin
2002
Satraplatin: leading the new generation of oral platinum agents
2009
The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction
1997
Mechanisms of acquired resistance to cisplatin
1994
PI3K/Akt signalling pathway and cancer
2003 Standout
Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma
2000
Cytokinesis-block micronucleus cytome assay
2007 Standout
Cellular accumulation of the anticancer agent cisplatin: A review
1993
Cisplatin and Adriamycin Resistance Are Associated with MutLα and Mismatch Repair Deficiency in an Ovarian Tumor Cell Line
1996 StandoutNobel
Cisplatin in cancer therapy: Molecular mechanisms of action
2014 Standout
In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin
1993
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: Relation to drug cytotoxicity and caspase-3 activation
2005
Investigating the relationship between the cell cycle and apoptosis using flow cytometry
2002
Repair of DNA interstrand cross-links
2001
Current and future potential roles of the platinum drugs in the treatment of ovarian cancer
2001
Macrophage Cytokines: Involvement in Immunity and Infectious Diseases
2014 Standout
New platinum antitumor complexes
1993
The status of platinum anticancer drugs in the clinic and in clinical trials
2010 Standout
The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat
1996
Satraplatin: an orally available platinum analog for the treatment of cancer
2006
Recent insights into platinum drug resistance in cancer
1998
Increased accumulation of p53 protein in cisplatin‐resistant ovarian cell lines
1993
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting
2005 StandoutNobel
Current status of the development of trans-platinum antitumor drugs
2000
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Preparation and Characterization of Noveltrans-[PtCl2(amine)(isopropylamine)] Compounds: Cytotoxic Activity and Apoptosis Induction inras-Transformed Cells
1999
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic Cells
2001 StandoutNobel
Transport of cisplatin and bis-acetato-ammine-dichlorocyclohexylamine Platinum(IV) (JM216) in human ovarian carcinoma cell lines: identification of a plasma membrane protein associated with cisplatin resistance.
1995
Inhibition of DNA Synthesis by a Platinum–Acridine Hybrid Agent Leads to Potent Cell Kill in Nonsmall Cell Lung Cancer
2011
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Organometallic Anticancer Compounds
2010 Standout
Influence of the Spacer Length on the in Vitro Anticancer Activity of Dinuclear Ruthenium−Arene Compounds
2008
Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells
1995
Current Status of Platinum-Based Antitumor Drugs
1999 Standout
Current Status and Future Prospects for Satraplatin, an Oral Platinum Analogue
2008
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
2001 StandoutNobel
Conformational flexibility and its potential influence on metabolic reactions for the anti-tumour compound a-ammine-bd-bis(butyrato)-cf-dichloro-e-cyclohexylamine platinum(IV)
1996
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Phase II Study of Picoplatin As Second-Line Therapy for Patients With Small-Cell Lung Cancer
2009
Mechanisms of Cancer Drug Resistance
2002 Standout
The events that occur when cisplatin encounters cells
1996
Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance
1999
BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin.
2000
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells
2005 Standout
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
Ischemic Cell Death in Brain Neurons
1999 Standout
Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro.
1995
The prediction of Raman spectra of platinum(II) anticancer drugs by density functional theory
2005
A comprehensive electron wavefunction analysis toolbox for chemists, Multiwfn
2024 Standout
Advances in Copper Complexes as Anticancer Agents
2013 Standout
AMycobacterium ulceransToxin, Mycolactone, Causes Apoptosis in Guinea Pig Ulcers and Tissue Culture Cells
2000
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Cisplatin Sensitizes Cancer Cells to Ionizing Radiation via Inhibition of Nonhomologous End Joining
2005
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Selective potentiation of platinum drug cytotoxicity in cisplatin-sensitive and-resistant human ovarian carcinoma cell lines by amphotericin B
1994
Works of CF O'Neill being referenced
Evaluation of novel ammine/amine platinum (IV) dicarboxylates in L1210 murine leukaemia cells sensitive and resistant to cisplatin, tetraplatin or carboplatin
1994
Retention of activity by the new generation platinum agent AMD0473 in four human tumour cell lines possessing acquired resistance to oxaliplatin
2002
Apoptotic and non-apoptotic cell death induced by cis and trans analogues of a novel ammine(cyclohexylamine)dihydroxodichloroplatinum(IV) complex
1996
Gene-specific repair of Pt/DNA lesions and induction of apoptosis by the oral platinum drug JM216 in three human ovarian carcinoma cell lines sensitive and resistant to cisplatin
1999
Cisplatin Induces Apoptosis in a Human Ovarian Carcinoma Cell Line without Concomitant Internucleosomal Degradation of DNA
1994
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
1992
Gene-specific repair of Pt/DNA lesions and induction of apoptosis by the oral platinum drug JM216 in three human ovarian carcinoma cell lines sensitive and resistant to cisplatin
1999
The cytotoxic action of four ammine/amine platinum(IV) dicarboxylates: a flow cytometric study
1996