Citation Impact
Citing Papers
Mitochondrial dysfunction in Parkinson's disease
2016
The PINK1/Parkin pathway regulates mitochondrial morphology
2008
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
2009 Standout
The Role of Oxidative Stress in Parkinson's Disease
2013
Reactive Oxygen Species in Inflammation and Tissue Injury
2013 Standout
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
2009
Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease
2010
Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle
2009
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons
2016
Sorting out release, uptake and processing of alpha‐synuclein during prion‐like spread of pathology
2015
The DNA-damage response in human biology and disease
2009 StandoutNature
Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance
2011
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
2009 Standout
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Parkinson disease
2017 Standout
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Magnetic resonance imaging as a potential biomarker for Parkinson's disease
2015
Mitochondrial dysfunction and molecular pathways of disease
2007
mTOR Signaling in Growth Control and Disease
2012 Standout
Inflammation and metabolic disorders
2006 StandoutNature
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
2010 Standout
Selective Activation of p38 Mitogen-Activated Protein Kinase in Dopaminergic Neurons of Substantia Nigra Leads to Nuclear Translocation of p53 in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Mice
2008
The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases
2016
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease
2011
Mitochondria in the aetiology and pathogenesis of Parkinson's disease
2008
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
2010 Standout
Exosomes in the Pathology of Neurodegenerative Diseases
2016
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
2010
Spreading of pathology in neurodegenerative diseases: a focus on human studies
2015
Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease
2014
M1 and M2 immune activation in Parkinson’s Disease: Foe and ally?
2014
Genetic Animal Models of Parkinson's Disease
2010
Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons
2009
Mitochondria Are a Major Source of Paraquat-induced Reactive Oxygen Species Production in the Brain
2007 Standout
Metabolic Activity Determines Efficacy of Macroautophagic Clearance of Pathological Oligomeric α-Synuclein
2009
Autophagy: Renovation of Cells and Tissues
2011 Standout
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
2009
What causes cell death in Parkinson's disease?
2009
Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?
2008
Autophagy in lysosomal storage disorders
2012
Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning
2011
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Chemokines in the MPTP model of Parkinson’s disease: Absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration
2006
Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1
2009
PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
2011
Parkinson's disease
2015 Standout
Caenorhabditis elegans expressing the Saccharomyces cerevisiae NADH alternative dehydrogenase Ndi1p, as a tool to identify new genes involved in complex I related diseases
2015
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Mitochondrial function and morphology are impaired in parkin‐mutant fibroblasts
2008
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Value of genetic models in understanding the cause and mechanisms of Parkinson’s disease
2008
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Neurotoxic in vivo models of Parkinson’s disease
2010
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair
2009
Mitochondrial association of alpha-synuclein causes oxidative stress
2008
Alzheimer's Disease
2010 Standout
Neuroinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention
2007
Non-motor features of Parkinson disease
2017 Standout
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
2011
Protective Effects of Positive Lysosomal Modulation in Alzheimer's Disease Transgenic Mouse Models
2011
Neuroinflammation and Oxidation/Nitration of α-Synuclein Linked to Dopaminergic Neurodegeneration
2008
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
C. elegans models of age-associated neurodegenerative diseases: Lessons from transgenic worm models of Alzheimer’s disease
2006
Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
2008
Targeting programmed cell death in neurodegenerative diseases
2003
The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
2010
Glia and alpha-synuclein in neurodegeneration: A complex interaction
2015
The Hallmarks of Aging
2013 Standout
Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease
2007
Mitochondrial DNA damage and repair in neurodegenerative disorders
2008
Autophagy and Neuronal Cell Death in Neurological Disorders
2012
Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10
2005
Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
2012 StandoutNobel
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Parkinson's Disease
2003 Standout
Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control
2011
Neurochemistry of Parkinson's disease
2007
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 Standout
Autophagy failure in A lzheimer's disease and the role of defective lysosomal acidification
2013
Recent Advances in the Genetics of Parkinson's Disease
2011
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
2010
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
2012 Standout
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
2012
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
Systemic exosomal siRNA delivery reduced alpha‐synuclein aggregates in brains of transgenic mice
2014
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Role of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative Diseases
2015
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson’s disease factors Pink1 and Parkin
2008
Autophagy and neurodegeneration
2015
Spermidine in health and disease
2018 StandoutScience
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson’s disease
2007
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
2008
The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
2007
Apoptosis-inducing factor: vital and lethal
2006
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
2013
Mutual exacerbation of peroxisome proliferator‐activated receptor γ coactivator 1α deregulation and α‐synuclein oligomerization
2014
Autophagy and Metabolism
2010 StandoutScience
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Exosomes as drug delivery vehicles for Parkinson's disease therapy
2015 Standout
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Pink1 Forms a Multiprotein Complex with Miro and Milton, Linking Pink1 Function to Mitochondrial Trafficking
2009
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease
2004
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
2010 Standout
Harnessing Functional Plasticity of Enzymes: A Fluorogenic Probe for Imaging 17β-HSD10 Dehydrogenase, an Enzyme Involved in Alzheimer's and Parkinson's Diseases
2007
Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
2005
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
ABAD enhances Aβ‐induced cell stress via mitochondrial dysfunction
2005
Works of Céline Perier being referenced
Similar Patterns of Mitochondrial Vulnerability and Rescue Induced by Genetic Modification of α-Synuclein, Parkin, and DJ-1 in Caenorhabditis elegans
2005
Toxin-induced models of Parkinson’s disease
2005
AMPA receptor antagonist LY293558 reverses preproenkephalin mRNA overexpression in the striatum of 6‐OHDA‐lesioned‐rats treated with l ‐dopa
2002
D-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
2003
Mitochondrial alterations in Parkinson’s disease: new clues
2008
Increased Expression and Redistribution of the Antiapoptotic Molecule Bcl-xL in Parkinson's Disease
2002
Apoptosis‐inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins
2010
Accumulation of mitochondrial DNA deletions within dopaminergic neurons triggers neuroprotective mechanisms
2013
Metabolic effects of nigrostriatal denervation in basal ganglia
2000
2004
Lysosomal dysfunction in Parkinson disease
2012
Mitochondrial Biology and Parkinson's Disease
2011
Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency
2012
Ablation of the Inflammatory Enzyme Myeloperoxidase Mitigates Features of Parkinson's Disease in Mice
2005
MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease
2004
Pathogenic Lysosomal Depletion in Parkinson's Disease
2010
Mitochondria and Programmed Cell Death in Parkinson's Disease: Apoptosis and Beyond
2011
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
2007
Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
2005
D-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
2003
The kinase domain of mitochondrial PINK1 faces the cytoplasm
2008
Lewy body extracts from Parkinson disease brains trigger α‐synuclein pathology and neurodegeneration in mice and monkeys
2013
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
2007
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration
2012
The Parkinson Disease Mitochondrial Hypothesis
2015