Citation Impact
Citing Papers
Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
2002 StandoutNobel
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
1995 StandoutNature
Effects of an Rb mutation in the mouse
1992 StandoutNature
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor
1991
Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95
1995 StandoutScience
Oncogenic kinase signalling
2001 StandoutNature
Bone marrow cells regenerate infarcted myocardium
2001 StandoutNature
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
1993 Nature
Transcriptional control and patterning of the pho-1 gene, an essential acid phosphatase expressed in the C. elegans intestine
2005
Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen
1989
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
1997 StandoutNature
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
The C. elegans intestine
2007
The E2F transcription factor is a cellular target for the RB protein
1991 Standout
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex
1992
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1991 StandoutNature
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Making Worm Guts: The Gene Regulatory Network of the Caenorhabditis elegans Endoderm
2002
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1993 Standout
Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation
1990
The cell cycle and the retinoblastoma protein family
1994
The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions
1991
Protein modules and signalling networks
1995 StandoutNature
pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest
1994 StandoutNature
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
1997
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins including the retinoblastoma protein and cyclin A
1992
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Molecular themes in oncogenesis
1991 StandoutNobel
Selected glimpses into the activation and function of Src kinase
2000
Disrupted dichotomous intracellular control of human papillomavirus infection in cancer of the cervix
1994 StandoutNobel
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
2003 StandoutNature
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
1997
Effects of activation-defective TBP mutations on transcription initiation in yeast
1994 StandoutNatureNobel
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
1998 StandoutNature
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes.
1991
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
1989
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
1993 StandoutNature
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
1994
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
The CBP co-activator is a histone acetyltransferase
1996 StandoutNature
Cell-specific proteomic analysis in Caenorhabditis elegans
2015
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
STATs and Gene Regulation
1997 StandoutScience
Tumor Suppressor Genes
1991 Science
Cancer Cell Cycles
1996 StandoutScience
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
Ku is associated with the telomere in mammals
1999 StandoutNobel
Crystal structure of yeast TATA-binding protein and model for interaction with DNA.
1993 StandoutNobel
E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.
1993 StandoutNobel
DNA-binding properties of the E1A-associated 300-kilodalton protein.
1992
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Induction of Transformation and p53-Dependent Apoptosis by Adenovirus Type 5 E4orf6/7 cDNA
1999
Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity
1990
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
Analysis with specific polyclonal antiserum indicates that the E1A-associated 300-kDa product is a stable nuclear phosphoprotein that undergoes cell cycle phase-specific modification.
1991
TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains
1990
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E.
1993
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Growth Factors and Cancer
1991 StandoutScience
The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
1998
Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth
1993
Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins
1991
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.
1994 Standout
A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding.
1990
A maize cDNA encoding a member of the retinoblastoma protein family: involvement in endoreduplication.
1996 StandoutNobel
Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters
1994
Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins
1992
Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53
1990 StandoutScience
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
1992
E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins
1992 Science
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis.
1993
DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1
1996 StandoutScience
Works of Cay Egan being referenced
Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530
1999
A Gut-to-Pharynx/Tail Switch in Embryonic Expression of the Caenorhabditis elegans ges-1 Gene Centers on Two GATA Sequences
1995
Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5.
1988
Mapping of Cellular Protein-Binding Sites on the Products of Early-Region 1A of Human Adenovirus Type 5
1988
Binding of the Rb1 protein to E1A products is required for adenovirus transformation.
1989
Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis.
1990