Standout Papers
Citation Impact
Citing Papers
Argonaute2 Is the Catalytic Engine of Mammalian RNAi
2004 StandoutScience
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
The Balance between the MIR164A and CUC2 Genes Controls Leaf Margin Serration in Arabidopsis
2006
An Argonaute Transports siRNAs from the Cytoplasm to the Nucleus
2008 Science
RNAi-Mediated Targeting of Heterochromatin by the RITS Complex
2004 Science
Establishment and Maintenance of a Heterochromatin Domain
2002 Science
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
Developmental Decline in Neuronal Regeneration by the Progressive Change of Two Intrinsic Timers
2013 StandoutScienceNobel
Nuclear Export of MicroRNA Precursors
2003 StandoutScience
Functional Genomic Analysis of RNA Interference in C. elegans
2005 StandoutScienceNobel
Redundancy and specialization among plant microRNAs: role of the MIR164 family in developmental robustness
2007
ARGONAUTE4 Control of Locus-Specific siRNA Accumulation and DNA and Histone Methylation
2003 Science
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
Regulation of Phosphate Homeostasis by MicroRNA in Arabidopsis
2005
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
A Family of MicroRNAs Present in Plants and Animals
2006
Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans
2006 StandoutScienceNobel
Novel and Stress-Regulated MicroRNAs and Other Small RNAs from Arabidopsis[W]
2004 Standout
Dual Effects of miR156-Targeted SPL Genes and CYP78A5/KLUH on Plastochron Length and Organ Size in Arabidopsis thaliana
2008
Small RNAs as big players in plant abiotic stress responses and nutrient deprivation
2007
The role of heterochromatin in centromere function
2005
Molecular mechanism of RNA silencing suppression mediated by p19 protein of tombusviruses
2004
Computational Identification of Plant MicroRNAs and Their Targets, Including a Stress-Induced miRNA
2004 Standout
RNA interference is required for normal centromere function infission yeast
2003
MicroRNAs
2004 Standout
Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene
2003
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs
2004 Standout
Interfering with hepatitis C virus RNA replication
2004 StandoutNobel
RNA interference: traveling in the cell and gaining functions?
2002
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
2003
The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development
2004
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
RNAi-mediated pathways in the nucleus
2005
Genetic and Functional Diversification of Small RNA Pathways in Plants
2004 Standout
A miRacle in plant development: Role of microRNAs in cell differentiation and patterning
2008
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence
2012 StandoutNatureNobel
RNAi: an ever-growing puzzle
2003
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
2004
Employment opportunities for non‐coding RNAs
2004
Arabidopsis endogenous small RNAs: highways and byways
2006
Dicer is essential for formation of the heterochromatin structure in vertebrate cells
2004
Differential Regulation of Strand-Specific Transcripts from Arabidopsis Centromeric Satellite Repeats
2005
MicroRNAs: small RNAs with a big role in gene regulation
2004 Standout
Embryonic Stem Cell-Specific MicroRNAs
2003
Spatio‐temporal accumulation of microRNAs is highly coordinated in developing plant tissues
2006
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
MicroRNA biogenesis: coordinated cropping and dicing
2005 Standout
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
2003
The microRNAs of Caenorhabditis elegans
2003
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
2005
Conservation and divergence of plant microRNA genes
2006
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain
2003 Nature
RNase III enzymes and the initiation of gene silencing
2004
Plant ARGONAUTES
2008
Regulation of Small RNA Accumulation in the Maize Shoot Apex
2009
microRNAs: Runts of the Genome Assert Themselves
2003
Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity
2004
MicroRNA Regulation of NAC-Domain Targets Is Required for Proper Formation and Separation of Adjacent Embryonic, Vegetative, and Floral Organs
2004
Regulation of heterochromatin by histone methylation and small RNAs
2004
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
2006 StandoutNobel
Chromatin and RNAi factors protect the C. elegans germline against repetitive sequences
2005
Structural determinants of RNA recognition and cleavage by Dicer
2007 StandoutNobel
Plasmodesmata
2002
Overlapping transcripts, double-stranded RNA and antisense regulation: A genomic perspective
2006
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
microRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants
2005 Standout
Suv39h-Mediated Histone H3 Lysine 9 Methylation Directs DNA Methylation to Major Satellite Repeats at Pericentric Heterochromatin
2003
Reduced expression of Dicer associated with poor prognosis in lung cancer patients
2005
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Argonaute proteins: key players in RNA silencing
2007
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
RISC Assembly Defects in the Drosophila RNAi Mutant armitage
2004
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase
2004
Origin, Biogenesis, and Activity of Plant MicroRNAs
2009 Standout
Small RNA-Mediated Quiescence of Transposable Elements in Animals
2010
The diverse functions of histone lysine methylation
2005 Standout
RITS acts in cis to promote RNA interference–mediated transcriptional and post-transcriptional silencing
2004
A Chromosome RNAissance
2002
Endogenous siRNAs Derived from a Pair of Natural cis-Antisense Transcripts Regulate Salt Tolerance in Arabidopsis
2005
Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi
2005
MicroRNAs and Other Tiny Endogenous RNAs in C. elegans
2003 StandoutNobel
Size Selective Recognition of siRNA by an RNA Silencing Suppressor
2003
RNA interference in protozoan parasites
2004
RNA silencing in plants
2004 StandoutNature
Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi
2003 Nature
Transcription and RNA interference in the formation of heterochromatin
2007 Nature
New microRNAs from mouse and human
2003
Nomenclature and functions of RNA-directed RNA polymerases
2006
The small RNA repertoire of Dictyostelium discoideum and its regulation by components of the RNAi pathway
2007 StandoutNobel
AtXRN4 Degrades mRNA in Arabidopsis and Its Substrates Include Selected miRNA Targets
2004
Small RNAs as Guardians of the Genome
2009
Structure and conserved RNA binding of the PAZ domain
2003 Nature
Revealing the world of RNA interference
2004 StandoutNatureNobel
miRBase: microRNA sequences, targets and gene nomenclature
2005 Standout
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
On the origin and functions of RNA-mediated silencing: from protists to man
2006
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Endogenous trans-Acting siRNAs Regulate the Accumulation of Arabidopsis mRNAs
2004
Identification and characterization of small RNAs involved in RNA silencing
2005
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
2004 Nature
ASRP: the Arabidopsis Small RNA Project Database
2004
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
Maintenance of heterochromatin by RNA interference of tandem repeats
2003
The role of RNA interference in heterochromatic silencing
2004 Nature
Two RNAi Complexes, RITS and RDRC, Physically Interact and Localize to Noncoding Centromeric RNAs
2004
Mechanisms of gene silencing by double-stranded RNA
2004 StandoutNature
miRNAs on the move: miRNA biogenesis and the RNAi machinery
2004
MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5′ region
2004
The functions of animal microRNAs
2004 StandoutNatureNobel
The Small RNA Profile during Drosophila melanogaster Development
2003
Perspective: machines for RNAi
2005
Argonaute2 Cleaves the Anti-Guide Strand of siRNA during RISC Activation
2005
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans -acting siRNAs in Arabidopsis
2004
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene
2003
Transcriptional silencing of a transgene by RNAi in the soma of C. elegans
2005
The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
2002
Submergence-responsive MicroRNAs are Potentially Involved in the Regulation of Morphological and Metabolic Adaptations in Maize Root Cells
2008
Role of MicroRNAs in Plant and Animal Development
2003 StandoutScienceNobel
Evidence for a piwi-Dependent RNA Silencing of the gypsy Endogenous Retrovirus by the Drosophila melanogaster flamenco Gene
2004
Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage
2008
Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits microRNAs and short interfering RNAs
2005
Ribo-gnome: The Big World of Small RNAs
2005 Science
Expression of Arabidopsis MIRNA Genes
2005
Evidence for Nuclear Processing of Plant Micro RNA and Short Interfering RNA Precursors
2003
Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena
2004
MicroRNA regulation of the CUC genes is required for boundary size control inArabidopsismeristems
2004
Chromatin Modifications by Methylation and Ubiquitination: Implications in the Regulation of Gene Expression
2006
Germ Line Transcripts Are Processed by a Dicer-Like Protein That Is Essential for Developmentally Programmed Genome Rearrangements of Tetrahymena thermophila
2005
Microarray analysis of microRNA expression in the developing mammalian brain
2004 Nobel
In vitro reconstitution of the human RISC-loading complex
2008 StandoutNobel
Dicer is required for chromosome segregation and gene silencing in fission yeast cells
2002 Nobel
Argonaute Slicing Is Required for Heterochromatic Silencing and Spreading
2006 Science
Non‐cell autonomous RNA silencing
2005
Dissection of a Natural RNA Silencing Process in the Drosophila melanogaster Germ Line
2004
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Small RNAs Correspond to Centromere Heterochromatic Repeats
2002 Science
Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast
2008 Science
MicroRNAs AND THEIR REGULATORY ROLES IN PLANTS
2006 Standout
RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast
2002
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production
2004
Modulation of floral development by a gibberellin-regulated microRNA
2004
Small RNAs: Classification, Biogenesis, and Function
2005
A Systemic Small RNA Signaling System in Plants
2004
Structural Basis for Double-Stranded RNA Processing by Dicer
2006 StandoutScienceNobel
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
2003 StandoutNobel
An epigenetic road map for histone lysine methylation
2003
Heterochromatin and Epigenetic Control of Gene Expression
2003 Science
Works of Catherine Kidner being referenced
Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi
2002 StandoutScience
Clonal analysis of the Arabidopsis root confirms that position, not lineage, determines cell fate
2000
Spatially restricted microRNA directs leaf polarity through ARGONAUTE1
2004 Nature
The developmental role of microRNA in plants
2004
<i>In Situ</i> Hybridization as a Tool to Study the Role of MicroRNAs in Plant Development
2006
Macro effects of microRNAs in plants
2002
The role of ARGONAUTE1 (AGO1) in meristem formation and identity
2005