Standout Papers
Citation Impact
Citing Papers
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
2012 StandoutNobel
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts
2002
Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis
1999
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Efficacy of gene therapy-delivered cytosine deaminase is determined by enzymatic activity but not expression
2007
Optical Rheology of Biological Cells
2005
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin
1995
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit
2007
The Arp2/3 complex branches filament barbed ends: functional antagonism with capping proteins
2000
Reconstitution In Vitro of the Motile Apparatus from the Amoeboid Sperm of Ascaris Shows That Filament Assembly and Bundling Move Membranes
1996
Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase
1999
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
The lamellipodium: where motility begins
2002
X-ray structure of a voltage-dependent K+ channel
2003 StandoutNatureNobel
Tumor necrosis factor, cancer and anticancer therapy
2004
Physiology of Cell Volume Regulation in Vertebrates
2009
Crystal structure and mechanism of a calcium-gated potassium channel
2002 StandoutNatureNobel
Polymer-drug conjugates: Recent development in clinical oncology
2008
Induction of cortical oscillations in spreading cells by depolymerization of microtubules
2001
Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice
2009
Nanoparticle therapeutics: an emerging treatment modality for cancer
2008 Standout
Blebs lead the way: how to migrate without lamellipodia
2008
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Blocking TNF-α in mice reduces colorectal carcinogenesis associated with chronic colitis
2008
Spontaneous regression of lung metastasis in the absence of tumor necrosis factor receptor p55
2004
Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development
1998
From JNK to Pay Dirt: Jun Kinases, their Biochemistry, Physiology and Clinical Importance
2005
Regulated portals of entry into the cell
2003 StandoutNature
Polycystin-1 and -2 Dosage Regulates Pressure Sensing
2009
Engineering the perfect (bacterial) cancer therapy
2010 Standout
Environmentally Controlled Invasion of Cancer Cells by Engineered Bacteria
2005
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Rho GTPases in cell biology
2002 StandoutNature
Reconstitution of actin-based motility of Listeria and Shigella using pure proteins
1999 Nature
Systemic administration of attenuated Salmonella choleraesuis in combination with cisplatin for cancer therapy
2005
Gelsolin, a Multifunctional Actin Regulatory Protein
1999
Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals
1998
Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice
2007
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Nanometer Analysis of Cell Spreading on Matrix-Coated Surfaces Reveals Two Distinct Cell States and STEPs
2004
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Filamin Associates with Smads and Regulates Transforming Growth Factor-β Signaling
2001
Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of l-arabinose as inducer of bacterial gene expression in vivo
2007
Phosphatidylinositol 3‐kinases in tumor progression
2001
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Non-equilibration of hydrostatic pressure in blebbing cells
2005 Nature
Focal adhesions – the cytoskeletal connection
2000
Immunity, Inflammation, and Cancer
2010 Standout
Carboxypeptidase G2-based gene-directed enzyme–prodrug therapy: a new weapon in the GDEPT armoury
2007
Cell Migration: A Physically Integrated Molecular Process
1996 Standout
Apoptosis
2002 Standout
Antisense therapy in oncology: new hope for an old idea?
2001
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Microtubule-binding agents: a dynamic field of cancer therapeutics
2010 Standout
Management of Metastatic Melanoma 2005
2006
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Bacteria in gene therapy: bactofection versus alternative gene therapy
2005
Differential gene expression in migrating renal epithelial cells after wounding
1995
Therapeutic vaccines for cancer: an overview of clinical trials
2014
Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro
2006
Physical and Functional Interaction of Filamin (Actin-binding Protein-280) and Tumor Necrosis Factor Receptor-associated Factor 2
2000
Tumour necrosis factor and cancer
2009
Inhibition of Tumor Growth and Metastasis by a Combination of Escherichia coli–mediated Cytolytic Therapy and Radiotherapy
2010
Bacterial therapies: completing the cancer treatment toolbox
2008
Quantification of human neutrophil motility in three-dimensional collagen gels. Effect of collagen concentration
1992
The Actin-Based Nanomachine at the Leading Edge of Migrating Cells
1999
Cancer-related inflammation
2008 StandoutNature
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK
2004
Life and Times of a Cellular Bleb
2007
Cellular Motility Driven by Assembly and Disassembly of Actin Filaments
2003 Standout
Poisons, Ruffles and Rockets: Bacterial Pathogens and the Host Cell Cytoskeleton
2000
The role and regulation of blebs in cell migration
2013
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Tissue Engineering
1993 StandoutScience
Dimensional and mechanical dynamics of active and stable edges in motile fibroblasts investigated by using atomic force microscopy
1999
P2X7 Receptor-Dependent Blebbing and the Activation of Rho-Effector Kinases, Caspases, and IL-1β Release
2003
Cellular and molecular mechanisms in cancer immune escape: a comprehensive review
2013
ENDOCYTOSIS AND MOLECULAR SORTING
1996
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
Calcium-Dependent Lateral Organization in Phosphatidylinositol 4,5-Bisphosphate (PIP2)- and Cholesterol-Containing Monolayers
2009
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
2004 Standout
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Mouse VAP33 is associated with the endoplasmic reticulum and microtubules
2000 StandoutNobel
Actin Binding Proteins: Regulation of Cytoskeletal Microfilaments
2003
An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators
1997
Targeting Signal Transduction Pathways in Colorectal Cancer—More Than Skin Deep
2005
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Targeting the TGFβ pathway for cancer therapy
2014
Analysis of the Actin–Myosin II System in Fish Epidermal Keratocytes: Mechanism of Cell Body Translocation
1997
Micro- and nanotechnology via reaction–diffusion
2005
pH-Operated Nanopistons on the Surfaces of Mesoporous Silica Nanoparticles
2010 StandoutNobel
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
2003
Therapeutic cancer vaccines
2015
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Activation of a Cl- current by hypotonic volume increase in human endothelial cells.
1994
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Chromatography in a Single Metal−Organic Framework (MOF) Crystal
2010 StandoutNobel
Engineered bidirectional communication mediates a consensus in a microbial biofilm consortium
2007 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Systemic Administration of an Attenuated, Tumor-TargetingSalmonella typhimuriumto Dogs with Spontaneous Neoplasia: Phase I Evaluation
2005
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Casey Cunningham being referenced
Cell Permeant Polyphosphoinositide-binding Peptides That Block Cell Motility and Actin Assembly
2001
TNFerade, an Adenovector Carrying the Transgene for Human Tumor Necrosis Factor α, for Patients With Advanced Solid Tumors: Surgical Experience and Long-Term Follow-Up
2005
Toxicity Assessment of Intratumoral Injection of the Herpes Simplex Type I Thymidine Kinase Gene Delivered by Retrovirus in Patients with Refractory Cancer
2001
Phase I Study of Oral CI-994 in Combination with Carboplatin and Paclitaxel in the Treatment of Patients with Advanced Solid Tumors
2004
Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients
2003
Actin-biding Protein-280 Binds the Stress-activated Protein Kinase (SAPK) Activator SEK-1 and Is Required for Tumor Necrosis Factor-α Activation of SAPK in Melanoma Cells
1997
Phase I Study of CT-2103, A Polymer-Conjugated Paclitaxel, and Carboplatin in Patients with Advanced Solid Tumors
2005
Identification of the Region in Actin-binding Protein that Binds to the Cytoplasmic Domain of Glycoprotein Ibä
1997
The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau
1997
A Phase I trial of h-ras antisense oligonucleotide ISIS 2503 administered as a continuous intravenous infusion in patients with advanced carcinoma
2001
Phase I and Pharmacokinetic Study of the Dolastatin-15 Analogue Tasidotin (ILX651) Administered Intravenously on Days 1, 3, and 5 Every 3 Weeks in Patients with Advanced Solid Tumors
2005
Cytoskeletal Protein ABP-280 Directs the Intracellular Trafficking of Furin and Modulates Proprotein Processing in the Endocytic Pathway
1997 StandoutNobel
Actin-Binding Protein Requirement for Cortical Stability and Efficient Locomotion
1992 Science
TNFerade Biologic, an Adenovector With a Radiation-Inducible Promoter, Carrying the Human Tumor Necrosis Factor Alpha Gene: A Phase I Study in Patients With Solid Tumors
2004
Phase 2 study of talabostat and cisplatin in stage IV melanoma
2005
Gelsolin, a Protein That Caps the Barbed Ends and Severs Actin Filaments, Enhances the Actin-Based Motility of Listeria monocytogenes in Host Cells
1998
Enhanced Motility in NIH 3T3 Fibroblasts That Overexpress Gelsolin
1991 Science
A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer.
2000
Phase 2 trial of talabostat in stage IV melanoma
2005
Actin-binding protein contributes to cell volume regulatory ion channel activation in melanoma cells.
1993
Actin polymerization and intracellular solvent flow in cell surface blebbing.
1995
Phase II Study of Belagenpumatucel-L, a Transforming Growth Factor Beta-2 Antisense Gene-Modified Allogeneic Tumor Cell Vaccine in Non–Small-Cell Lung Cancer
2006