Carsten Spanka

Empowering biomedical discovery with AI agents

Emergence of large-scale cell death through ferroptotic trigger waves

A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase