Citation Impact
Citing Papers
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
2015 StandoutNobel
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
2006 StandoutScience
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
2011
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Quartz-Seq: a highly reproducible and sensitive single-cell RNA sequencing method, reveals non-genetic gene-expression heterogeneity
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
A Cell Surfaceome Map for Immunophenotyping and Sorting Pluripotent Stem Cells
2012
Overcoming the Specific Toxicity of Large Plasmids Electrotransfer in Primary Cells In Vitro
2016
E1-L2 Activates Both Ubiquitin and FAT10
2007
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding
1998
RNA Helicase A Interacts with RISC in Human Cells and Functions in RISC Loading
2007
Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain
2011
P-glycoprotein: from genomics to mechanism
2003
Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ Cells
2013
Selective Excision of 5-Carboxylcytosine by a Thymine DNA Glycosylase Mutant
2013
DPPA4 modulates chromatin structure via association with DNA and core histone H3 in mouse embryonic stem cells
2010
Small non-coding RNAs in animal development
2008
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Smart-seq2 for sensitive full-length transcriptome profiling in single cells
2013 Standout
A unique regulatory phase of DNA methylation in the early mammalian embryo
2012 Nature
Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates
2010
Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development
2011
TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation
2011
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells
2012
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
2014 Standout
Genes Expressed in Neurons of Adult Male Drosophila
1997 StandoutNobel
The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy
1999
Transcription Dynamics
2009
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
DNA methylation: roles in mammalian development
2013 Standout
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development
2013
DNA demethylation by DNA repair
2009
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
2011
Hydroxylation mediates chromatin demethylation
2012
The Yeast NuA4 and Drosophila MSL Complexes Contain Homologous Subunits Important for Transcription Regulation
2001
Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
2014 Nature
Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues
2010
Molecular Characterization of Hepatitis C Virus
1998 StandoutNobel
The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila
2001
MDR1 haplotypes significantly minimize intracellular uptake and transcellular P‐gp substrate transport in recombinant LLC‐PK1 cells
2006
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Dppa2 knockdown-induced differentiation and repressed proliferation of mouse embryonic stem cells
2009
Relative tolerance of mesostable and thermostable protein homologs to extensive mutation
2006
Epigenetic Reprogramming of Mouse Germ Cells toward Totipotency
2010
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Developmental Pluripotency-associated 4 (DPPA4) Localized in Active Chromatin Inhibits Mouse Embryonic Stem Cell Differentiation into a Primitive Ectoderm Lineage
2007
chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
2017
Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics
2013
Parallel mechanisms of epigenetic reprogramming in the germline
2012
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos
2012 Nature
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
2010 Nature
Chromatin dynamics during cellular reprogramming
2013 Nature
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation
2009
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming
2013
Mechanism and Stem‐Cell Activity of 5‐Carboxycytosine Decarboxylation Determined by Isotope Tracing
2012
Ubiquitin and ubiquitin-like proteins as multifunctional signals
2005
Active DNA demethylation by Gadd45 and DNA repair
2012
Viral and cellular RNA helicases as antiviral targets
2005
DNA Demethylation Dynamics
2011
Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming
2013
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
Gold nanoparticles in biomedical applications: recent advances and perspectives
2011 Standout
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
2008 Nature
Replication‐coupled passive DNA demethylation for the erasure of genome imprints in mice
2012
Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2
2012 Nature
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
2009 Standout
Dissecting direct reprogramming through integrative genomic analysis
2008 Nature
Applications of gold nanoparticles in cancer nanotechnology
2008
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
2008 Nature
Functional Characterization of Coding Polymorphisms in the HumanMDR1 Gene Using a Vaccinia Virus Expression System
2002
Replication of hepatitis C virus
2007 StandoutNobel
Selective Stimulation of Hepatitis C Virus and Pestivirus NS5B RNA Polymerase Activity by GTP
1999
Orally Absorbed Cyclic Peptides
2017
The dsRNA binding protein family: critical roles, diverse cellular functions
2003
Replication of hepatitis C virus
2000
The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal
1995
APOBEC2 Is a Monomer in Solution: Implications for APOBEC3G Models
2012 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
The Curious Chemical Biology of Cytosine: Deamination, Methylation,and Oxidation as Modulators of Genomic Potential
2011
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability
2005
Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity
1997
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Global Protein Stability Profiling in Mammalian Cells
2008 Science
Efficient Initiation of HCV RNA Replication in Cell Culture
2000 StandoutScienceNobel
Transcriptional control of human p53-regulated genes
2008 Standout
In vitro reconstitution of the human RISC-loading complex
2008 StandoutNobel
A Functional Interaction between the Survival Motor Neuron Complex and RNA Polymerase II
2001
Hepatitis C Virus RNA Synthesis in a Cell-Free System Isolated from Replicon-Containing Hepatoma Cells
2003 StandoutNobel
Essential Roles of ECAT15-2/Dppa2 in Functional Lung Development
2011 StandoutNobel
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation
2010 StandoutNobel
Mutational analysis of the hepatitis C virus RNA helicase
1997
Translating the Histone Code
2001 StandoutScience
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis
2016 StandoutNobel
Otitis Media Incidence and Impact on the Auditory Brain Stem Response in Lipopolysaccharide‐Nonresponsive C3H/HeJ Mice
1997
TAPping into mRNA Export
2001 StandoutScienceNobel
Equality for X Chromosomes
1995 Science
The hepatitis C virus NS4A protein: interactions with the NS4B and NS5A proteins
1997
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
2013 StandoutScienceNobel
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
The Pluripotency-Associated GeneDppa4Is Dispensable for Embryonic Stem Cell Identity and Germ Cell Development but Essential for Embryogenesis
2009
Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila
1995
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
microRNA Functions
2007 Standout
Modulation of Hepatitis C Virus NS5A Hyperphosphorylation by Nonstructural Proteins NS3, NS4A, and NS4B
1999
Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells
1997
Multiple Enzymatic Activities Associated with Recombinant NS3 Protein of Hepatitis C Virus
1998
mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans
2011 StandoutNobel
Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes
2001
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets
2009 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Caroline Lee being referenced
Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway
2010 Science
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
2002
Maternal microRNAs are essential for mouse zygotic development
2007
Generation ofstella-GFP transgenic mice: A novel tool to study germ cell development
2006
Cloning and analysis of gene regulation of a novel LPS-inducible cDNA
1995
FAT10 Plays a Role in the Regulation of Chromosomal Stability
2006
Chromatin dynamics during epigenetic reprogramming in the mouse germ line
2008 Nature
p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers
2006
Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers
2003
Tracing the Derivation of Embryonic Stem Cells from the Inner Cell Mass by Single-Cell RNA-Seq Analysis
2010
Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres
2011
Development of a new permeability assay using low‐efflux MDCKII cells
2011
Exploiting Internal Ribosome Entry Sites in Gene Therapy Vector Design
2004
Effect of MDR1 Haplotype on Risk of Parkinson Disease
2005
Enzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells by using the herpes simplex virus amplicon system
1996
Dppa2 and Dppa4 Are Closely Linked SAP Motif Genes Restricted to Pluripotent Cells and the Germ Line
2006
HIV-1 Protease Inhibitors Are Substrates for theMDR1 Multidrug Transporter
1998
APPLICATIONS OF GOLD NANOPARTICLES IN THE EARLY DETECTION OF CANCER
2007
Human RNA helicase A is homologous to the maleless protein of Drosophila
1993
Molecular cloning and characterization of a murine LPS-inducible cDNA.
1994
Switching substrate preference of thermophilic xylose isomerase from D-xylose to D-glucose by redesigning the substrate binding pocket.
1991
Early diagnosis of oral cancer based on the surface plasmon resonance of gold nanoparticles.
2007
Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine
2012 Science