Citation Impact
Citing Papers
Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma
2009 Standout
Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment
2015 Science
Human Multidrug Resistance Associated Protein 4 Confers Resistance to Camptothecins
2005
Hypoxia-Inducible Factor-1-Dependent Repression of E-cadherin in von Hippel-Lindau Tumor Suppressor–Null Renal Cell Carcinoma Mediated by TCF3, ZFHX1A, and ZFHX1B
2006 StandoutNobel
Active Efflux of CPT-11 and Its Metabolites in Human KB-Derived Cell Lines
1999
Pharmacokinetics, Metabolism, and Excretion of Irinotecan (CPT-11) Following I.V. Infusion of [14C]CPT-11 in Cancer Patients
2000
Predicting Oral Absorption and Bioavailability
2003
Role of cellular calcium homeostasis in toxic liver injury induced by the pyrrolizidine alkaloid senecionine and the alkenal trans‐4‐OH‐2‐hexenal
1987
Imaging beyond the proteome
2012 StandoutNobel
Therapeutic potential of resveratrol: the in vivo evidence
2006 Standout
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: A North American Brain Tumor Consortium study1
2006
Cytotoxic and genotoxic effects of energetic compounds on bacterial and mammalian cells in vitro
1999
Methods for Predicting Human Drug Metabolism
2006
Characteristics of SARS-CoV-2 and COVID-19
2020 Standout
SARS and MERS: recent insights into emerging coronaviruses
2016 Standout
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
2013
Coronaviruses — drug discovery and therapeutic options
2016
Principles of nanoparticle design for overcoming biological barriers to drug delivery
2015 Standout
Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac
2013
Albumin–drug interaction and its clinical implication
2013 Standout
Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies
2017
Fast screening of ketamine in biological samples based on molecularly imprinted photonic hydrogels
2013
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Large language models in medicine
2023 Standout
DrugBank: a knowledgebase for drugs, drug actions and drug targets
2007 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mechanism-Based Inhibition of Cytochrome P450 3A4 by Therapeutic Drugs
2005
Lipid peroxidation and cellular damage caused by the pyrrolizidine alkaloid senecionine, the alkenal trans-4-hydroxy-2-hexenal, and related alkenals
1987
Targeting multidrug resistance in cancer
2006 Standout
Insights from nanomedicine into chloroquine efficacy against COVID-19
2020 Standout
Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity
2002
Microfluidic organs-on-chips
2014 Standout
Integration ofin silicoandin vitroplatforms for pharmacokinetic–pharmacodynamic modeling
2010
Determination of the Chelatable Iron Pool of Isolated Rat Hepatocytes by Digital Fluorescence Microscopy Using the Fluorescent Probe, Phen Green Sk
1999
Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
1999
A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload
2001 Standout
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
2001 Standout
Metabolomics: beyond biomarkers and towards mechanisms
2016 Standout
The effect of the pyrrolizidine alkaloid integerrimine on the chromosomes of mouse bone marrow cells
1990
Ontogeny of Hepatic and Renal Systemic Clearance Pathways in Infants
2002
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
2007
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
2020 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Mammalian aldehyde oxidases: genetics, evolution and biochemistry
2007
Herb-Drug Interactions
2005 Standout
Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death
2017
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
2020 Standout
Ontogeny of Hepatic and Renal Systemic Clearance Pathways in Infants
2002
Control of Neglected Tropical Diseases
2007 Standout
Topoisomerase I inhibitors: camptothecins and beyond
2006 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Drug discovery and development for neglected parasitic diseases
2006
Exploitation of the HIF axis for cancer therapy
2004
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
1991 Standout
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
p53 Mutations in Human Cancers
1991 StandoutScience
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Metabolism of the pyrrolizidine alkaloid metabolite trans-4-hydroxy-2-hexenal by mouse liver aldehyde dehydrogenases
1986
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)
2020 Standout
Azole-Based Energetic Salts
2011 Standout
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Trans -4-Hydroxy-2-Hexenal: a Reactive Metabolite from the Macrocyclic Pyrrolizidine Alkaloid Senecionine
1985 Science
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
The Many Roles for Fluorine in Medicinal Chemistry
2008 Standout
Allocation of Physician Time in Ambulatory Practice: A Time and Motion Study in 4 Specialties
2016 Standout
Factors Affecting Physician Professional Satisfaction and Their Implications for Patient Care, Health Systems, and Health Policy.
2014
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
In vivo covalent binding of trans-4-hydroxy-2-hexenal to rat liver macromolecules
1985
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma
2008 Standout
Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism
1997
Short-term administration of (-)-epigallocatechin gallate reduces hepatic steatosis and protects against warm hepatic ischemia/reperfusion injury in steatotic mice
2005
Genotoxicity and cytotoxicity of selected pyrrolizidine alkaloids, A possible alkenal metabolite of the alkaloids, and related alkenals
1986
PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs
2008 Standout
Isolation and culturing of hepatocytes from human livers
1992
Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases
2017
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Liver cell models in in vitro toxicology.
1998
Characterization of Vesicular Stomatitis Virus Recombinants That Express and Incorporate High Levels of Hepatitis C Virus Glycoproteins
2002 StandoutNobel
The Mononuclear Molybdenum Enzymes
2014 Standout
Bevacizumab Plus Irinotecan in Recurrent Glioblastoma Multiforme
2007 Standout
Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
2014
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Molecular imprinting: perspectives and applications
2016 Standout
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of Carol E. Green being referenced
A Survey Analysis Suggests That Electronic Health Records Will Yield Revenue Gains For Some Practices And Losses For Many
2013
Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography–tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent
2005
Variation of Hepatic Methotrexate 7‐Hydroxylase Activity in Animals and Humans
1999
A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents
2013
Structure-activity relationship for the intrinsic hepatotoxicity of dinitrotoluenes
1990
A parallel chiral–achiral liquid chromatographic method for the determination of the stereoisomers of ketamine and ketamine metabolites in the plasma and urine of patients with complex regional pain syndrome
2010
Toxicity of a quinocarmycin analog, DX-52-1, in rats and dogs in relation to clinical outcome
2003
Prediction of In Vivo Interaction Between Triazolam and Erythromycin Based on In Vitro Studies Using Human Liver Microsomes and Recombinant Human CYP3A4
2000
Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data
1997
Prediction of in Vivo Drug-Drug Interactions between Tolbutamide and Various Sulfonamides in Humans Based on in Vitro Experiments
2000
Pharmacokinetics of the Antimalarial Drug, AQ-13, in Rats and Cynomolgus Macaques
2004
Metabolism and cytotoxicity of acetaminophen in hepatocytes isolated from resistant and susceptible species
1984
Biliary excretion mechanism of CPT-11 and its metabolites in humans: involvement of primary active transporters.
1998
Metabolism, cytotoxicity, and genotoxicity of the pyrrolizidine alkaloid senecionine in primary cultures of rat hepatocytes
1981
Glucuronidation oftrans-resveratrol by human liver and intestinal microsomes and UGT isoforms
2006
Characterization of isolated Fe-loaded rat hepatocytes prepared by collagenase perfusion
1982
Functional integrity of isolated rat hepatocytes prepared by whole liver vs biopsy perfusion
1983
Absorption, Tissue Distribution and Elimination of 4-[3H]-Epigallocatechin Gallate in Beagle Dogs
2003