Citation Impact
Citing Papers
Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
CD4+ Count–Guided Interruption of Antiretroviral Treatment
2006 Standout
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
Mutational Analysis of Trp-229 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase (RT) Identifies This Amino Acid Residue as a Prime Target for the Rational Design of New Non-Nucleoside RT Inhibitors
2000
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
The group II intron ribonucleoprotein precursor is a large, loosely packed structure
2010 StandoutNobel
Domain structure and three-dimensional model of a group II intron-encoded reverse transcriptase
2004
Use of organic cosmotropic solutes to crystallize flexible proteins: application to T7 RNA polymerase and its complex with the inhibitor T7 lysozyme
1997 StandoutNobel
Crystal Structures of the Bacillus stearothermophilus CCA-Adding Enzyme and Its Complexes with ATP or CTP
2002 StandoutNobel
Crystal Structures of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant Mutant
1996
Allosteric Inhibitor Development Targeting HIV‐1 Integrase
2011
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
2000 StandoutNatureNobel
N‐terminally tagged prion protein supports prion propagation in transgenic mice
1997 StandoutNobel
Cloning vectors for the production of proteins in Dictyostelium discoideum
1995
Structure of unliganded HIV-1 reverse transcriptase at 2.7 å resolution: implications of conformational changes for polymerization and inhibition mechanisms
1996
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Structural Mechanisms of HIV Drug Resistance
1996
RNase H activity of HIV reverse transcriptases is confined exclusively to the dimeric forms
1992
Protein Crystallization on Lipid Layers and Structure Determination of the RNA Polymerase II Transcription Initiation Complex
1999 StandoutNobel
The dynamic disulphide relay of quiescin sulphydryl oxidase
2012 StandoutNatureNobel
Yeast RNA Polymerase II at 5 Å Resolution
1999 StandoutNobel
Building a Replisome from Interacting Pieces
1999 StandoutNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Functionally interacting telomerase RNAs in the yeast telomerase complex
1997 StandoutNobel
Structural Basis for the Resilience of Efavirenz (DMP-266) to Drug Resistance Mutations in HIV-1 Reverse Transcriptase
2000
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes
1998 StandoutNobel
Interaction of Retroviral Reverse Transcriptase with Template–Primer Duplexes during Replication
1997
Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome
1999
Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance 1 1Edited by J. Karn
1998
Aptamer Displacement Identifies Alternative Small-Molecule Target Sites that Escape Viral Resistance
2007
Relating the Structure ofHIV-1 Reverse Transcriptaseto Its Processing Step
2000
Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors 1 1Edited by J. Karn
2001
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase
1995
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
2018 Standout
Polyalanine Reconstruction from Cα Positions Using the ProgramCALPHACan Aid Initial Phasing of Data by Molecular Replacement Procedures
1997
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
Crystal structure of a thermostable Bacillus DNA polymerase l large fragment at 2.1 Å resolution
1997
Role of Residues in the Tryptophan Repeat Motif for HIV-1 Reverse Transcriptase Dimerization
2003
HIV Drug Resistance
2004
Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates
1995
An open and closed case for all polymerases
1999
Phenylethylthiazolylthiourea (PETT) Non-nucleoside Inhibitors of HIV-1 and HIV-2 Reverse Transcriptases
2000
Features and development of Coot
2010 Standout
Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors
1995
The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance
2001
Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
2002 StandoutNobel
The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor
1997
Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions
1997
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2.8 Å resolution
1998
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
2005 StandoutNatureNobel
The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor
1998
DNA Polymerases: Structural Diversity and Common Mechanisms
1999 StandoutNobel
Ribosome Structure and the Mechanism of Translation
2002 StandoutNobel
Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1
2006
Binding of the Second Generation Non-nucleoside Inhibitor S-1153 to HIV-1 Reverse Transcriptase Involves Extensive Main Chain Hydrogen Bonding
2000
Lysine Methylation as a Routine Rescue Strategy for Protein Crystallization
2006
Crystal Structure of the Ribosome at 5.5 Å Resolution
2001 StandoutScience
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Functional Nucleic Acid Sensors
2009 Standout
A Water-Based Mechanism of Specificity and Resistance for Lapatinib with ErbB Family Kinases
2012
Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains
2005
Synthesis, Anti-HIV Activity, and Metabolic Stability of New Alkenyldiarylmethane HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors
2005
Crystallographic Analysis of the Binding Modes of Thiazoloisoindolinone Non-Nucleoside Inhibitors to HIV-1 Reverse Transcriptase and Comparison with Modeling Studies
1999
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance
1998 StandoutScience
Computer Simulation of the Chemical Catalysis of DNA Polymerases: Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
Binding and kinetic properties of HIV-1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription.
1996
A Trypanosoma brucei Protein Complex That Binds G-overhangs and Co-purifies with Telomerase Activity
2002 StandoutNobel
Telomerases
1999
Crystal Structures of HIV-1 Reverse Transcriptase in Complex with Carboxanilide Derivatives,
1998
Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases
2005 StandoutNobel
Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89
1997
Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates
2008 Science
Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy
2003 StandoutNobel
The Guanine Nucleotide-Binding Switch in Three Dimensions
2001 StandoutScience
Functional Aptamers and Aptazymes in Biotechnology, Diagnostics, and Therapy
2007
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
Electrogenerated Chemiluminescence and Its Biorelated Applications
2008 Standout
The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: Pattern fittings and the identification of a functional site
1999 StandoutNobel
The Motif D Loop of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Is Critical for Nucleoside 5′-Triphosphate Selectivity
1999
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
The Halogen Bond
2016 Standout
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids
1999
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
STRUCTURAL INSIGHTS INTO TRANSLATIONAL FIDELITY
2005 StandoutNobel
Structure of importin-β bound to the IBB domain of importin-α
1999 Nature
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Design of MKC-442 (Emivirine) Analogues with Improved Activity Against Drug-Resistant HIV Mutants
1999
Crystal Structures of Zidovudine- or Lamivudine-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptases Containing Mutations at Codons 41, 184, and 215
2002
Works of Carl Ross being referenced
Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration
1998
Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors
1995
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design
1995
Formatin of heterodimers of human‐immunodeficiency‐virus‐type‐1 reverse transcriptase by recombination of separately purified subunits
1992
Crystals of HIV-1 Reverse Transcriptase Diffracting to 2·2 Å Resolution
1994
High resolution structures of HIV-1 RT from four RT–inhibitor complexes
1995
Rapid purification and characterisation of HIV‐1 reverse transcriptase and RNaseH engineered to incorporate a C‐terminal tripeptide α‐tubulin epitope
1991
3′-Azido-3′-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes
1998
Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors
1996
Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor
1997