Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ
2013 StandoutNobel
Architecture of human mTOR complex 1
2015 Science
Clonal competition with alternating dominance in multiple myeloma
2012
Simultaneous prediction of protein folding and docking at high resolution
2009 StandoutNobel
Three-Dimensional Model of Salmonella ’s Needle Complex at Subnanometer Resolution
2011 Science
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
Bulk RNA degradation by nitrogen starvation‐induced autophagy in yeast
2014 StandoutNobel
Structures of the RNA-guided surveillance complex from a bacterial immune system
2011 StandoutNatureNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy
2015 StandoutNobel
Structure of the cholera toxin secretion channel in its closed state
2010
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
TRAPP complexes in membrane traffic: convergence through a common Rab
2010
mTOR Signaling in Growth Control and Disease
2012 Standout
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
2011
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
2014
Elongator stabilizes microtubules to control central spindle asymmetry and polarized trafficking of cell fate determinants
2022
Structural basis of starvation-induced assembly of the autophagy initiation complex
2014 StandoutNobel
A Double S Shape Provides the Structural Basis for the Extraordinary Binding Specificity of Dscam Isoforms
2008 StandoutNobel
Structural overview of the bacterial injectisome
2010
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
2013
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
Probing cellular protein complexes using single-molecule pull-down
2011 Nature
The Intrinsically Disordered Protein Atg13 Mediates Supramolecular Assembly of Autophagy Initiation Complexes
2016 StandoutNobel
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis
2010
A Vast Repertoire of Dscam Binding Specificities Arises from Modular Interactions of Variable Ig Domains
2007 StandoutNobel
Tor forms a dimer through an N-terminal helical solenoid with a complex topology
2016
Crystal structure of the C‐terminal domain of the Salmonella type III secretion system export apparatus protein InvA
2010
The machinery of macroautophagy
2013 Standout
Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies
2007
A role for Raptor phosphorylation in the mechanical activation of mTOR signaling
2013
Structural and Functional Studies on the Interaction of GspC and GspD in the Type II Secretion System
2011
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Secretins: dynamic channels for protein transport across membranes
2011
A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly
2013 StandoutNobel
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout
2009
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
The Adaptor Function of TRAPPC2 in Mammalian TRAPPs Explains TRAPPC2-Associated SEDT and TRAPPC9-Associated Congenital Intellectual Disability
2011
The Needle Component of the Type III Secreton of Shigella Regulates the Activity of the Secretion Apparatus
2005
The type III secretion injectisome
2006
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Single-particle reconstruction from EM images of helical filaments
2007
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
2010
Allo-network drugs: harnessing allostery in cellular networks
2011
Bacterial Nanomachines: The Flagellum and Type III Injectisome
2010
Structural and Functional Studies on the N-terminal Domain of the Shigella Type III Secretion Protein MxiG
2011
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Myosin V Transports Secretory Vesicles via a Rab GTPase Cascade and Interaction with the Exocyst Complex
2011 StandoutNobel
Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex
2011
The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles
2013 StandoutNobel
Causes and consequences of aneuploidy in cancer
2012
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Preventing Replication Stress to Maintain Genome Stability: Resolving Conflicts between Replication and Transcription
2012
SPRING – An image processing package for single-particle based helical reconstruction from electron cryomicrographs
2013
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
2016 StandoutNobel
Transport according to GARP: receiving retrograde cargo at the trans-Golgi network
2010
Secretion systems in Gram-negative bacteria: structural and mechanistic insights
2015
Structure of the cytoplasmic domain ofYersinia pestisYscD, an essential component of the type III secretion system
2012
Heterogeneity of Large Macromolecular Complexes Revealed by 3D Cryo-EM Variance Analysis
2008
Structure and Function of PilQ, a Secretin of the DNA Transporter from the Thermophilic Bacterium Thermus thermophilus HB27
2011
Type III secretion systems shape up as they ship out
2009
Topology and Organization of the Salmonella typhimurium Type III Secretion Needle Complex Components
2010
The Hallmarks of Aging
2013 Standout
A conserved domain in type III secretion links the cytoplasmic domain of InvA to elements of the basal body
2010
Protein delivery into eukaryotic cells by type III secretion machines
2006 Nature
Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex
2017
Self-chaperoning of the Type III Secretion System Needle Tip Proteins IpaD and BipD
2006
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry
2019
Crystal Structure of the N-Terminal Domain of the Secretin GspD from ETEC Determined with the Assistance of a Nanobody
2009
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
The Structure of a Filamentous Bacteriophage
2006
Atg9 Vesicles Recruit Vesicle-tethering Proteins Trs85 and Ypt1 to the Autophagosome Formation Site
2012 StandoutNobel
Structure and Interactions of the Cytoplasmic Domain of the Yersinia Type III Secretion Protein YscD
2012
Structure of the heterotrimeric complex that regulates type III secretion needle formation
2007
AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets
2011
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
Exorcising the Exocyst Complex
2012
Molecular model of a type III secretion system needle: Implications for host-cell sensing
2006
Interaction of MxiG with the cytosolic complex of the type III secretion system controls Shigella virulence
2012
The role of raptor in the mechanical load‐induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy
2018
C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking
2011
The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
2011 Science
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
2013
Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
2011
Maintaining order: COG complex controls Golgi trafficking, processing, and sorting
2019
Structure of components of an intercellular channel complex in sporulating Bacillus subtilis
2012
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
2015 StandoutNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
2016 StandoutNobel
Structure of the basal components of a bacterial transporter
2012
Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings
2011 StandoutNobel
What's the point of the type III secretion system needle?
2008
The blueprint of the type-3 injectisome
2012
Interactions of the Transmembrane Polymeric Rings of the Salmonella enterica Serovar Typhimurium Type III Secretion System
2010 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
COPII and COPI Traffic at the ER-Golgi Interface
2011
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Works of Calvin K. Yip being referenced
Structural Polymorphism in Bacterial EspA Filaments Revealed by Cryo-EM and an Improved Approach to Helical Reconstruction
2006
The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments
2010
Structural characterization of a type III secretion system filament protein in complex with its chaperone
2004
A Structure-Based Mechanism for Vesicle Capture by the Multisubunit Tethering Complex Dsl1
2009
Molecular organization of the COG vesicle tethering complex
2010
Structural characterization of the molecular platform for type III secretion system assembly
2005 Nature
Molecular architecture of the complete COG tethering complex
2016
New structural insights into the bacterial type III secretion system
2006
Molecular architecture of the TRAPPII complex and implications for vesicle tethering
2010
Structural characterization of theSaccharomyces cerevisiaeautophagy regulatory complex Atg17-Atg31-Atg29
2013
Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition
2010
Structural Organization of the Anaphase-Promoting Complex Bound to the Mitotic Activator Slp1
2007
An Alpha Motif at Tas3 C Terminus Mediates RITS cis Spreading and Promotes Heterochromatic Gene Silencing
2009
Molecular interactions of theSaccharomyces cerevisiaeAtg1 complex provide insights into assembly and regulatory mechanisms
2015
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system
2009 StandoutNobel
Molecular architecture of the yeast Elongator complex reveals an unexpected asymmetric subunit arrangement
2016
Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation
2013
Primitive interleukin 3 null hematopoietic cells transduced with BCR-ABL show accelerated loss after culture of factor-independence in vitro and leukemogenic activity in vivo
2002
Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate
2010