Standout Papers
Citation Impact
Citing Papers
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
2009 StandoutScience
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma
2012
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
2007 StandoutScience
Randomized Pilot Trial of Bariatric Surgery Versus Intensive Medical Weight Management on Diabetes Remission in Type 2 Diabetic Patients Who Do NOT Meet NIH Criteria for Surgery and the Role of Soluble RAGE as a Novel Biomarker of Success
2014
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
2005 StandoutNature
Extracellular HMGB1 as a Proinflammatory Cytokine
2004
RAGE‐dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
2009
Purification and Characterization of Mouse Soluble Receptor for Advanced Glycation End Products (sRAGE)
2004
S100A7 and the progression of breast cancer
2004
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Lectin‐like oxidized low density lipoprotein receptor‐1 (LOX‐1) serves as an endothelial receptor for advanced glycation end products (AGE)
2002
S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-κB signaling
2012
Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice
2004
RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response
2002
AGEs and Diabetic Retinopathy
2010
Modification of Proteins In Vitro by Physiological Levels of Glucose
2003
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
The intracrine hypothesis and intracellular peptide hormone action
2003
HMGB1 is a potent trigger of arthritis
2004
Necroptosis and its role in inflammation
2015 StandoutNature
Advanced glycation and endothelial functions: A link towards vascular complications in diabetes
2004
The biology of the receptor for advanced glycation end products and its ligands
2000
Expression of receptors for advanced glycation end‐products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer
2001
The immunogenetics of asthma and eczema: a new focus on the epithelium
2004
Alarmins: awaiting a clinical response
2012
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Receptor for Advanced Glycation End Products (RAGE) Signaling Induces CREB-dependent Chromogranin Expression during Neuronal Differentiation
2002
Cell death, BAX activation, and HMGB1 release during infection with Chlamydia
2004
Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE–/– mice
2008
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
2002 StandoutNature
Monocytes promote natural killer cell interferon gamma production in response to the endogenous danger signal HMGB1
2004
Increased expression of HMGB1 is associated with poor prognosis in human bladder cancer
2012
Hallmarks of aging: An expanding universe
2023 Standout
Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
2003
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Crosslink breakers: a new approach to cardiovascular therapy
2004
Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway
2002 StandoutNobel
Pathological Roles of Advanced Glycation End Product Receptors SR‐A and CD36
2005
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
2017 Standout
Atherosclerosis and diabetes: The rage connection
2000
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
2001
Pattern Recognition Receptors and Inflammation
2010 Standout
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
2001
RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes
2005
Severe Sepsis and Septic Shock
2013 Standout
Regulation of monocyte migration by amphoterin (HMGB1)
2004
The AGE‐receptor in the pathogenesis of diabetic complications
2001
Receptor for Advanced Glycation End Products, Inflammation, and Accelerated Periodontal Disease in Diabetes: Mechanisms and Insights Into Therapeutic Modalities
2001
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Nuclear factor κB: a potential therapeutic target in atherosclerosis and thrombosis
2004
Does Accumulation of Advanced Glycation End Products Contribute to the Aging Phenotype?
2010
Putative roles of kinin receptors in the therapeutic effects of angiotensin 1-converting enzyme inhibitors in diabetes mellitus
2004
Platelet Activation and Atherothrombosis
2007 Standout
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
2009 Standout
Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function
2004
Central role of RAGE-dependent neointimal expansion in arterial restenosis
2003
RAGE (receptor for advanced glycation end products): a central player in the inflammatory response
2004
Down-regulation of Lysyl Oxidase-induced Tumorigenic Transformation in NRK-49F Cells Characterized by Constitutive Activation of Ras Proto-oncogene
2001
Neurodegeneration and Inflammation
2008
The development of allergic inflammation
2008 StandoutNature
How dying cells alert the immune system to danger
2008
Receptor for advanced glycation end-products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apoE-deficient mouse
2010
Intracellular high mobility group B1 protein (HMGB1) represses HIV-1 LTR-directed transcription in a promoter- and cell-specific manner
2003
High mobility group box chromosomal protein 1: A novel proinflammatory mediator in synovitis
2002
RAGE is the Major Receptor for the Proinflammatory Activity of HMGB1 in Rodent Macrophages
2005
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Differential effects between amphoterin and advanced glycation end products on colon cancer cells
2003
Regulation of Vascular Endothelial Growth Factor Expression by Advanced Glycation End Products
2001
Scavenger receptors for oxidized and glycated proteins
2003
Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Theraphy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial
2007
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
RAGE: A New Target for the Prevention and Treatment of the Vascular and Inflammatory Complications of Diabetes
2000
Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic disease
2001
High mobility group box 1 protein, a cue for stem cell recruitment
2004
The receptor for advanced glycation end‐products (RAGE) directly binds to ERK by a D‐domain‐like docking site
2003
Diabetes and advanced glycation endproducts
2002
RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease
2002
Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
2004
Blockade of Receptor for Advanced Glycation End-Products Restores Effective Wound Healing in Diabetic Mice
2001
Origin and physiological roles of inflammation
2008 StandoutNature
Addicted to Death
2004
Sterile inflammation: sensing and reacting to damage
2010 Standout
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
2005 Standout
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
The Pathophysiology and Treatment of Sepsis
2003 Standout
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Cellular signalling of the receptor for advanced glycation end products (RAGE)
2013
Points of control in inflammation
2002 StandoutNature
Atherosclerosis
2000 StandoutNature
Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)
2008
Advanced glycation end-products: a review
2001 Standout
Calcium Signaling
2007 Standout
NEW EMBO MEMBERS' REVIEW: The double life of HMGB1 chromatin protein: architectural factor and extracellular signal
2001
Hepatoma-derived Growth Factor Is a Neurotrophic Factor Harbored in the Nucleus
2004
The inflammatory reflex
2002 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock
2007
Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects
2003
Frailty in elderly people
2013 Standout
Involvement of Microglial Receptor for Advanced Glycation Endproducts (RAGE) in Alzheimer's Disease: Identification of a Cellular Activation Mechanism
2001
Molecular Mechanisms of Tumor Necrosis Factor α Gene Expression in Monocytic Cells via Hyperglycemia-induced Oxidant Stress-dependent and -independent Pathways
2000
Inflammasomes in health and disease
2012 StandoutNature
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
HMGB1, an architectural chromatin protein and extracellular signalling factor, has a spatially and temporally restricted expression pattern in mouse brain
2003
Central role of RAGE-dependent neointimal expansion in arterial restenosis
2003
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2015 StandoutNobel
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Reactive Carbonyls Are a Major Th2-Inducing Damage-Associated Molecular Pattern Generated by Oxidative Stress
2011
Increased Expression of the DNA-Binding Cytokine HMGB1 in Human Atherosclerotic Lesions
2004
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-α and NF-κB
2005
Advanced Glycation End Products
2006 Standout
Clinical Implications of Extracellular HMGA1 in Breast Cancer
2019
Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis
2004
The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells
2001
Glycation, Inflammation, and RAGE
2003
Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis
2000
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins
2003
Activation of gene expression in human neutrophils by high mobility group box 1 protein
2003
Borna Disease Virus Phosphoprotein Binds a Neurite Outgrowth Factor, Amphoterin/HMG-1
2001
Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes
2005 Standout
The Immunology of Mucosal Models of Inflammation
2002
RAGE Blockade Stabilizes Established Atherosclerosis in Diabetic Apolipoprotein E–Null Mice
2002
RAGE Regulates the Metabolic and Inflammatory Response to High-Fat Feeding in Mice
2014
Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging
2020
Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells
2003
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
2001
Receptor for Advanced Glycation End Products Mediates Inflammation and Enhanced Expression of Tissue Factor in Vasculature of Diabetic Apolipoprotein E–Null Mice
2001
Platelet Expression Profiling and Clinical Validation of Myeloid-Related Protein-14 as a Novel Determinant of Cardiovascular Events
2006
HMGB1 and RAGE in Inflammation and Cancer
2010
RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts
2009
Exogenous High-Mobility Group Box 1 Protein Induces Myocardial Regeneration After Infarction via Enhanced Cardiac C-Kit + Cell Proliferation and Differentiation
2005
High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes
2000
Overexpression of high mobility group box 1 in gastrointestinal stromal tumors with KIT mutation.
2003
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
The Inflammatory Response to Cell Death
2008
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Danger Signals in the Initiation of the Inflammatory Response after Myocardial Infarction
2013
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products
2003
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
2004 Standout
S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules
2006
RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways
2004
Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis.
2002
Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.
2000
Dual roles for HMGB1: DNA binding and cytokine
2001
Granulocyte Macrophage Colony-Stimulating Factor Regulates Dendritic Cell Content of Atherosclerotic Lesions
2006
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
2018 Standout
Acute Hyperglycemia Causes Intracellular Formation of CML and Activation of ras, p42/44 MAPK, and Nuclear Factor κB in PBMCs
2003
DAMPs, PAMPs and alarmins: all we need to know about danger
2006 Standout
RAGE Axis
2004
Calcium-dependent and -independent interactions of the S100 protein family
2006
Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation
2004
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
2001
Works of Caifeng Fu being referenced
N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression
1999
Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases
2000 Nature
Expression of Advanced Glycation End Products and Their Cellular Receptor RAGE in Diabetic Nephropathy and Nondiabetic Renal Disease
2000
RAGE Mediates a Novel Proinflammatory Axis
1999 Standout
Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE
2002