Citation Impact
Citing Papers
Active Efflux of CPT-11 and Its Metabolites in Human KB-Derived Cell Lines
1999
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
Oxidation-induced changes in human lens epithelial cells 2. Mitochondria and the generation of reactive oxygen species
2006
Inositol phosphates and cell signalling
1989 StandoutNature
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Regulation of calcium influx by second messengers in rat mast cells
1988 StandoutNatureNobel
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
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The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
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The Formation of Ceramide-1-phosphate during Neutrophil Phagocytosis and Its Role in Liposome Fusion
1998 StandoutNobel
Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs
2004
Targeting multidrug resistance in cancer
2006 Standout
Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity
2002
In Vivo and in Vitro Reconstitution of Atg8 Conjugation Essential for Autophagy
2004 StandoutNobel
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
1992 Standout
Overproduction, purification, and characterization of chlorocatechol dioxygenase, a non-heme iron dioxygenase with broad substrate tolerance
1991
Ontogeny of Hepatic and Renal Systemic Clearance Pathways in Infants
2002
Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate
2013
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
1999 StandoutNature
Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis
2007 StandoutNobel
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Resonance Raman Studies of Catecholate and Phenolate Complexes of Recombinant Human Tyrosine Hydroxylase
1995
Lipids and thyroid hormones
1988
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
Lipid polymorphism and the functional roles of lipids in biological membranes
1979 Standout
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Serotonin modulates a specific potassium current in the sensory neurons that show presynaptic facilitation in Aplysia.
1982 StandoutNobel
Iron Catalysis in Organic Synthesis
2015 Standout
Oxidative damage and mitochondrial decay in aging.
1994 Standout
3d Transition Metals for C–H Activation
2018 Standout
Tumour‐promoting phorbol esters inhibit agonist‐induced phosphatidate formation and Ca2+ flux in human platelets
1985
A single-molecule diode
2005 StandoutNobel
Geometric and Electronic Structure/Function Correlations in Non-Heme Iron Enzymes
1999 Standout
Kinetics of the hydroperoxide-dependent dealkylation reactions catalyzed by rabbit liver microsomal cytochrome P-450.
1980
Primary amines as uncouplers of electron transport from hydroxylation in the secondary-amine mono-oxygenase system of Pseudomonas aminovorans
1972
pH-induced metal-ligand cross-links inspired by mussel yield self-healing polymer networks with near-covalent elastic moduli
2011 Standout
A model for receptor-regulated calcium entry
1986 Standout
Mössbauer studies of cytochrome P-450cam
1973
Diacylglycerol kinase from pig brain. Purification and phospholipid dependencies.
1983
A rapid stimulation of phosphatidylinositol metabolism in rabbit leukocytes by pseudomonal leukocidin
1983
Recent Advances in Transition Metal Catalyzed Oxidation of Organic Substrates with Molecular Oxygen
2005 Standout
Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation
1983 StandoutScienceNobel
Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450
1976
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
Preparation and properties of ferrous chloroperoxidase complexes with dioxygen, nitric oxide, and an alkyl isocyanide. Spectroscopic dissimilarities between the oxygenated forms of chloroperoxidase and cytochrome P-450.
1985
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Calcium and the control of synaptic strength by learning
1981 StandoutNatureNobel
Molecular Biology of Learning: Modulation of Transmitter Release
1982 StandoutScienceNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
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The role of protein kinase C in cell surface signal transduction and tumour promotion
1984 StandoutNature
Quantum Chemical Approach to the Assignment of Iron−Catecholate Vibrations and Isotopic Substitution Shifts
1996
A fundamental system of cellular energy homeostasis regulated by PGC-1α
2007
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
Mechanisms of slow postsynaptic potentials
1981 Nature
Crystal Structures of Substrate and Substrate Analog Complexes of Protocatechuate 3,4-Dioxygenase: Endogenous Fe3+ Ligand Displacement in Response to Substrate Binding,
1997
Definitive Evidence for Monoanionic Binding of 2,3-Dihydroxybiphenyl to 2,3-Dihydroxybiphenyl 1,2-Dioxygenase from UV Resonance Raman Spectroscopy, UV/Vis Absorption Spectroscopy, and Crystallography
2002
Aerobic Copper-Catalyzed Organic Reactions
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Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase
1985 StandoutNature
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
Cytochrome P450cam and its complexes, Mo¨ssbauer parameters of the heme iron
1976
A Cellular Mechanism of Classical Conditioning in Aplysia : Activity-Dependent Amplification of Presynaptic Facilitation
1983 StandoutScienceNobel
Plasma-membrane location of phosphatidylinositol hydrolysis in rabbit neutrophils stimulated with formylmethionyl-leucylphenylalanine
1982
Ca2+ Oscillations Induced by Hormonal Stimulation of Individual Fura-2-loaded Hepatocytes
1989 StandoutNobel
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Resonance Raman studies on protocatechuate 3,4-dioxygenase inhibitor complexes
1981
Lysophosphatidic acid can activate platelets without increasing 32P-labelling of phosphatidic acid
1984
Liver cell models in in vitro toxicology.
1998
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Leukotriene B4 and phosphatidic acid are calcium ionophores. Studies employing arsenazo III in liposomes.
1982
Inhibition by Carbon Monoxide of the Secondary‐Amine Mono‐oxygenase of Pseudomonas aminovorans and the Photochemical Action Spectrum for Its Reversal
1975
The Pressure Dependence of the Spin Equilibrium in Camphor‐Bound Ferric Cytochrome P‐450
1982
New Functional Model Complexes of Intradiol-Cleaving Catechol Dioxygenases: Properties and Reactivity of CuII(L)(O2Ncat)
2007
Heme-Containing Oxygenases
1996 Standout
Direct C−H Transformation via Iron Catalysis
2010 Standout
P450cam: Oxygenated complexes stabilized at low temperature
1977
Spectral intermediates in the reaction of oxygen with purified liver microsomal cytochrome P-450
1976
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Phosphatidylinositol turnover in platelet activation; Calcium mobilization and protein phosphorylation
1982
Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones
1982 StandoutNatureNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Cytochrome P450cam: SS- dimer and -SH derivative reactivities
1978
Phospholipid Turnover in Hormone Action
1984
Simultaneous binding of nitric oxide and isotopically labeled substrates or inhibitors by reduced protocatechuate 3,4-dioxygenase.
1993
Camphor binding of Pseudomonas putida cytochrome P-450. Kinetics and thermodynamics of the reaction
1972
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of C.A. Tyson being referenced
Comparison of amphetamine metabolism using isolated hepatocytes from five species including human.
1986
Comparative metabolism of tolbutamide by isolated hepatocytes from rat, rabbit, dog, and squirrel monkey.
1984
Report on the International Workshop on the Use of Human In Vitro Liver Preparations to Study Drug Metabolism in Drug Development
1995
Mechanism of uncoupling in mitochondria: uncouplers as ionophores for cycling cations and protons.
1976
P-450cam hydroxylase: substrate-effector and electron-transport reactions
1971
Phospholipids as ionophores.
1976
Biliary excretion mechanism of CPT-11 and its metabolites in humans: involvement of primary active transporters.
1998
Response of isolated hepatocytes to organic and inorganic cytotoxins
1983
4-Nitrocatechol as a colorimetric probe for non-heme iron dioxygenases.
1975
Characterization of ANIT-Induced Toxicity using Precision-Cut Rat and Dog Liver Slices Cultured in a Dynamic Organ Roller System
2006