Standout Papers
- Ruthenium ammine disulfides (1979)
- Pentaammineruthenium dimethyl chalcogenide complexes (1979)
- Manifestations of sulfur to sulfur through-space interactions in complex ion spectra (1978)
- Manifestations of sulfur to sulfur through-bond interactions in complex ion spectra (1981)
- Trimethylsulfonium ion as a ligand: synthesis and characterizaton of pentaamminetrimethylsulfoniumruthenium tris(hexafluorophosphate) (1978)
Citation Impact
Citing Papers
Hallmarks of Cancer: The Next Generation
2011 Standout
Targeting microRNAs in cancer: rationale, strategies and challenges
2010
Screening for antisense modulation of dystrophin pre-mRNA splicing
2002
Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with palliative end points.
1996 Standout
Incorporation of (R)- and (S)-3′,4′-seco-thymidine into oligodeoxynucleotides: hybridization properties and enzymatic stability
1994
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
Induction of apoptosis in fibroblasts by c-myc protein
1992 Standout
Prostate-specific antigen as a measure of disease outcome in metastatic hormone-refractory prostate cancer.
1993
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Approaches for the sequence-specific knockdown of mRNA
2003
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Mutations in the p53 gene occur in diverse human tumour types
1989 StandoutNature
Inhibition of Egr-1 expression reverses transformation of prostate cancer cells in vitro and in vivo
2003
Association of H19 Promoter Methylation with the Expression of H19 and IGF-II Genes in Adrenocortical Tumors
2002
Nanotechnology: Intelligent Design to Treat Complex Disease
2006
A DNA metalloenzyme with DNA ligase activity
1995 StandoutNatureNobel
Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates
1998 StandoutNobel
Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging
2009 Standout
siRNA function in RNAi: A chemical modification analysis
2003
Revealing the world of RNA interference
2004 StandoutNatureNobel
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Local Supercoil-Stabilized DNA Structure
1991
Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents
1991 Nature
Molecular mechanisms of action of antisense drugs
1999
Block of c‐Fos and JunB Expression by Antisense Oligonucleotides Inhibits Light‐induced‐Phase Shifts of the Mammalian Circadian Clock
1995
Cutting Edge: Antisense Knockdown of Inducible Nitric Oxide Synthase Inhibits Induction of Experimental Autoimmune Encephalomyelitis in SJL/J Mice
1998 StandoutNobel
p53 Mutations in Human Cancers
1991 StandoutScience
Topographic organization of sensory projections to the olfactory bulb
1994 StandoutNobel
Molecular Targets for AIDS Therapy
1990 Science
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
1998
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
2010
Nucleic Acid Selection and the Challenge of Combinatorial Chemistry
1997
RNA-peptide fusions for the in vitro selection of peptides and proteins
1997 StandoutNobel
Modulation of Anxiety and Neuropeptide Y-Y1 Receptors by Antisense Oligodeoxynucleotides
1993 Science
Antitumor Activity of Systemically Delivered Ribozymes Targeting Murine Telomerase RNA
2004 StandoutNobel
Combinatorially selected guanosine-quartet structureis a potent inhibitor of human immunodeficiency virus envelope-mediated cellfusion.
1994
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
1994 StandoutNobel
Skiing the Reaction Rate Slopes
1992 StandoutScienceNobel
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
mRNA coding for oxytocin is present in axons of the hypothalamo-neurohypophysial tract.
1990
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Frequency and structure of p53 rearrangements in human osteosarcoma.
1990
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Electron tunneling through covalent and noncovalent pathways in proteins
1987 StandoutNobel
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma.
1994
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Chemical synthesis of DNA and DNA analogs
1991
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Processing of Nontelomeric 3′ Ends by Telomerase: Default Template Alignment and Endonucleolytic Cleavage
1996
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
Electronic coupling through saturated hydrocarbon bridges
1993
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
1999
Molecular Rods. 1. Simple Axial Rods
1999 Standout
Telomerase in kinetoplastid parasitic protozoa
1999 StandoutNobel
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice
2002
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Real time detection of DNA⋅RNA hybridization in living cells
1998
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Electron transfers in chemistry and biology
1985 Standout
Metal–Organic Frameworks in Biomedicine
2011 Standout
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse
2000
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Dispersed Polaron Simulations of Electron Transfer in Photosynthetic Reaction Centers
1989 StandoutScienceNobel
Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase
2011 StandoutNobel
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
1998
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles
2004 StandoutNobel
Specificity of short interfering RNA determined through gene expression signatures
2003
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
1997 StandoutNobel
Femtosecond dynamics of DNA-mediated electron transfer
1999 StandoutNobel
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Works of C.A. Stein being referenced
Physicochemical properties of phospborothioate oligodeoxynucleotides
1988
The experimental use of antisense oligonucleotides: a guide for the perplexed
2001
Antisense Oligonucleotides in Cancer
2000
Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells
1993
Does antisense exist?
1995
Genetic Changes in Human Adrenocortical Carcinomas
1989
Phosphorothioate antisense oligodeoxynucleotides: questions of specificity
1996
Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein
1997
Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer.
1992
Keeping the biotechnology of antisense in context
1999
Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides
1989
Exploiting the potential of antisense: beyond phosphorothioate oligodeoxynucleotides
1996
Effect of Phosphorothioate Homo-oligodeoxy nucleotides on Herpes Simplex Virus Type 2-induced DNA Polymerase
1989
Facilitating oligonucleotide delivery: helping antisense deliver on its promise.
1996
Manifestations of sulfur to sulfur through-bond interactions in complex ion spectra
1981 StandoutNobel
Sequence-independent induction of Sp1 transcription factor activity by phosphorothioate oligodeoxynucleotides.
1994
Long-range intervalence electron tunneling through fully saturated systems
1982
Characterization of oligonucleotide transport into living cells.
1989
Progress in the Delivery of Therapeutic Oligonucleotides: Organ/Cellular Distribution and Targeted Delivery of OligonucleotidesIn Vivo
2003
Inhibition of herpes simplex virus type 2 growth by phosphorothioate oligodeoxynucleotides
1990
Phosphorothioate oligodeoxycytidine interferes with binding of HIV-1 gp120 to CD4.
1991
Delivery of c-myc Antisense Phosphorothioate Oligodeoxynucleotides to Hematopoietic Cells in Culture by Liposome Fusion: Specific Reduction in c-myc Protein Expression Correlates with Inhibition of Cell Growth and DNA Synthesis
1988
Antisense oligonucleotides: basic concepts and mechanisms.
2002
Oligodeoxynucleotides as inhibitors of gene expression: a review.
1988
Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis.
1990
Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.
1989