Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
2008 StandoutNobel
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1
2002
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Activation of chemosensitive neurons in the ventrolateral medulla by capsaicin in cats
1997
Pharmacological characterization of the vanilloid receptor in the rat dorsal spinal cord
1997
Multiple capsaicin-induced currents in isolated rat sensory neurons
1996
A novel agonist, phorbol 12-phenylacetate 13-acetate 20-homovanillate, abolishes positive cooperativity of binding by the vanilloid receptor
1996
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Receptors, channels, and signalling in the urothelial sensory system in the bladder
2016
Mechanisms and Therapeutic Potential of Vanilloids (Capsaicin-like Molecules)
1993
URODYNAMIC EFFECTS OF INTRAVESICAL RESINIFERATOXIN IN HUMANS: PRELIMINARY RESULTS IN STABLE AND UNSTABLE DETRUSOR
1997
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Outflow of endogenous aspartate and glutamate from the rat spinal dorsal horn in vitro by activation of low- and high-threshold primary afferent fibers. Modulation by μ-opioids
1991
INTRAVESICAL CAPSAICIN AS A TREATMENT FOR REFRACTORY DETRUSOR HYPERREFLEXIA: A DUAL CENTER STUDY WITH LONG-TERM FOLLOWUP
1997
Desensitization of bladder sensory fibers by intravesical capsaicin or capsaicin analogs. A new strategy for treatment of urge incontinence in patients with spinal detrusor hyperreflexia or bladder hypersensitivity disorders
1998
Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferret
1993
Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence
1993 Standout
The effect of capsaicin on voltage‐gated calcium currents and calcium signals in cultured dorsal root ganglion cells
1990
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Disturbed intestinal movement, bile reflux to the stomach, and deficiency of c-kit-expressing cells in WsWs mutant rats
1995
Effects of carbonyl cyanide p-trichloromethoxyphenylhydrazone (CCCP) and of ruthenium red (RR) on capsaicin-evoked neuropeptide release from peripheral terminals of primary afferent neurones
1990
Activation of the cAMP transduction cascade contributes to the mechanical hyperalgesia and allodynia induced by intradermal injection of capsaicin
1997
Capsaicin and pain mechanisms
1995
The vanilloid (capsaicin) receptor: Receptor types and species differences
1994
Behavioral characterization of the excitatory and desensitizing effects of intravesical capsaicin and resiniferatoxin in the rat
1993
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
1998 StandoutNobel
Effect of capsazepine on the release of calcitonin gene‐related peptide‐like immunoreactivity (CGRP‐LI) induced by low pH, capsaicin and potassium in rat soleus muscle
1993
Temporal parameters of desensitization to intravesical resiniferatoxin in the rat
1994
Action of polygodial, a sesquiterpene isolated from Drymis winteri, in the guinea-pig ileum and trachea `in vitro'
1998
Effects of ruthenium red and capsazepine on C‐fibres in the rabbit iris
1993
Vanilloid receptors in the urinary bladder: regional distribution, localization on sensory nerves, and species-related differences
1993
Proton inhibition of [3H]resiniferatoxin binding to vanilloid (capsaicin) receptors in rat spinal cord
1995
Effect of capsaicin and resiniferatoxin on peptidergic neurons in cultured dorsal root ganglion
1992
Therapeutic potential of capsaicin-like molecules: Studies in animals and humans
1992
Vanilloid receptors: new insights enhance potential as a therapeutic target
1996
Low‐threshold heat response antagonized by capsazepine in chick sensory neurons, which are capsaicin‐insensitive
2000
Desensitization of capsaicin-evoked neuropeptide release — Influence of Ca2+ and temperature
1990
Agonist-receptor efficacy II: agonist trafficking of receptor signals
1995
G Protein-coupled Receptors
1998 StandoutNobel
Treatment parameters of desensitization to capsaicin
1992
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
A non‐pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors
1999
TRP channels as cellular sensors
2003 StandoutNature
Ruthenium red as a capsaicin antagonist
1991
Species-related variations in the effects of capsaicin on urinary bladder functions: relation to bladder content of substance P-like immunoreactivity
1987
Capsaicin-like activity of some natural pungent substances on peripheral endings of visceral primary afferents
1990
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Distinct structure-activity relations for stimulation of 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes
1996
Detection of capsaicin-evoked release of glutamate from spinal dorsal horn slices of rat with on-line monitoring system
1993
The role of nitric oxide in mediating non-adrenergic non-cholinergic relaxation in longitudinal muscle of human taenia coli
1992
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Treating the Human Bladder with Capsaicin: Is It Safe?
1998
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
The L-Arginine-Nitric Oxide Pathway
1993 Standout
Characterization of a peripheral vanilloid (capsaicin) receptor in the urinary bladder of the rat
1993
EM574, an erythromycin derivative, is a motilin receptor agonist in the rabbit
1997 StandoutNobel
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Effects of capsazepine against capsaicin- and proton-evoked excitation of single airway C-fibres and vagus nerve from the guinea-pig
1995
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Effects of the capsaicin analogue resiniferatoxin on spinal nociceptive mechanisms in the rat: behavioral, electrophysiological and in situ hybridization studies
1997
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
The sensory-efferent function of capsaicin-sensitive sensory neurons
1988
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Activation of primary afferent neurons by thermal stimulation
1990
Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus
2007
Tetracaine attenuates irritancy without attenuating desensitization produced by intravesical resiniferatoxin in the rat
1994
Evidence for two independent modes of activation of the ‘efferent’ function of capsaicin-sensitive nerves
1988
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
The pharmacology of the efferent function of sensory nerves.
1991
Capsaicin‐, Resiniferatoxin‐, and Lactic Acid‐Evoked Vascular Effects in the Pig Nasal Mucosain vivowith Reference to Characterization of the Vanilloid Receptor
1996
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
Functional and metabolic evidence for two different vanilloid (VN1 and VN2) receptors in perfused rat hindlimb
1995
Anandamide-Evoked Activation of Vanilloid Receptor 1 Contributes to the Development of Bladder Hyperreflexia and Nociceptive Transmission to Spinal Dorsal Horn Neurons in Cystitis
2004
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Afferent Nerve Regulation of Bladder Function in Health and Disease
2009
Anti-allergic effects and oedema inhibition caused by the extract of Drymis winteri
1997
Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro
2009
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Protons: small stimulants of capsaicin-sensitive sensory nerves
1994
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Characterization of the capsaicin‐sensitive component of cyclophosphamide‐induced inflammation in the rat urinary bladder
1994
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
2000 StandoutNature
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
A non-pungent resiniferatoxin analogue, phorbol 12-phenylacetate 13 acetate 20-homovanillate, reveals vanilloid receptor subtypes on rat trigeminal ganglion neurons
1998
Capsaicin-induced biphasic oxygen uptake in rat muscle: Antagonism by capsazepine and ruthenium red provides further evidence for peripheral vanilloid receptor subtypes ()
1996
Regional differences in endothelin converting enzyme activity in rat brain: inhibition by phosphoramidon and EDTA
1992 StandoutNobel
C-Terminal amidated peptides: Production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity
1994
The Cloned Rat Vanilloid Receptor VR1 Mediates Both R-Type Binding and C-Type Calcium Response in Dorsal Root Ganglion Neurons
1999
NITRERGIC TRANSMISSION: NITRIC OXIDE AS A MEDIATOR OF NON‐ADRENERGIC, NON‐CHOLINERGIC NEURO‐EFFECTOR TRANSMISSION
1992
ELECTROMOTIVE DRUG ADMINISTRATION OF LIDOCAINE TO ANESTHETIZE THE BLADDER BEFORE INTRAVESICAL CAPSAICIN
1998
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
Entrainment of Duodenal Activity to Periodic Feeding
1987
Modification of aspirin and ethanol-induced mucosal damage in rats by intragastric application of resiniferatoxin
1995
Pharmacological Characterization of the Vanilloid Receptor in the Rat Isolated Vas Deferens
1996
Clinical and Urodynamic Effects of Intravesical Capsaicin Treatment in Patients with Chronic Traumatic Spinal Detrusor Hyperreflexia
1995
Differential Activation and Desensitization of Sensory Neurons by Resiniferatoxin
1997
Pungent products from garlic activate the sensory ion channel TRPA1
2005 StandoutNobel
Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors
1998 StandoutScience
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Tachykinin receptors in the guinea-pig isolated bronchi
1991
Involvement of neurokinin receptors in the induction but not the maintenance of mechanical allodynia in rat flexor motoneurones.
1995
Cystometric Evidence that Capsaicin-Sensitive Nerves Modulate the Afferent Branch of Micturition Reflex in Humans
1989
Similarities and Differences between the Responses of Rat Sensory Neurons to Noxious Heat and Capsaicin
1999
CHEMICAL ACTIVATORS OF SENSORY NEURONS
1997
TRPA1 mediates formalin-induced pain
2007 StandoutNobel
A rapid capsaicin-activated current in rat trigeminal ganglion neurons.
1994
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Entrainment of the Circadian Clock in the Liver by Feeding
2001 StandoutScience
Nonpeptide Tachykinin Receptor Antagonists. II. Pharmacological and Pharmacokinetic Profile of SB-222200, a Central Nervous System Penetrant, Potent and Selective NK-3 Receptor Antagonist
2000
Neuronal Plasticity: Increasing the Gain in Pain
2000 StandoutScience
The overactive bladder: Pharmacologic basis of drug treatment
1997
Desensitization of Bladder Sensory Fibers by Intravesical Capsaicin has Long Lasting Clinical and Urodynamic Effects in Patients With Hyperactive or Hypersensitive Bladder Dysfunction
1997
Euphorbium: Modern research on its active principle, resiniferatoxin, revives an ancient medicine
1997
Works of C.A. Maggi being referenced
Motor effect of neurokinins on the rat duodenum: evidence for the involvement of substance K and substance P receptors.
1986
Effect of acute or chronic administration of imipramine on spinal and supraspinal micturition reflexes in rats.
1989
Role of C-terminal amidation on the biological activity of neurokinin A derivatives with agonist and antagonist properties.
1993
Effect of thiorphan on tachykinin-induced potentiation of nerve-mediated contractions of the rat isolated vas deferens.
1989
In vivo effects of neurokinin B on rat urinary bladder motility: Involvement of tachykinin NK1 and NK2 receptors
1994
Evidence for the presence of a septide-sensitive tachykinin receptor in the circular muscle of the guinea-pig ileum
1993
Cyclophosphamide cystitis in rats: involvement of capsaicin-sensitive primary afferents
1992
Effect of endothelin-1, endothelin-3 and C-terminal hexapeptide, endothelin (16–21) on motor activity in rats
1990
Visceromotor responses to calcitonin gene-related peptide (CGRP) in the rat lower urinary tract: evidence for a transmitter role in the capsaicin-sensitive nerves of the ureter
1987
Similarities and differences in the action of resiniferatoxin and capsaicin on central and peripheral endings of primary sensory neurons
1990
Activity of SR 142801 at peripheral tachykinin receptors
1995
Neurochemical evidence for the activation of the ‘efferent’ function of capsaicin-sensitive nerves by lowering of the pH in the guinea-pig urinary bladder
1990
A comparison of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens
1993
Cadmium chloride induces contractions of the rat isolated urinary bladder by activation of capsaicin-sensitive sensory nerves
1988
Release of sensory neuropeptides from dural venous sinuses of guinea pig
1990
The effect of calcium free medium and nifedipine on the release of substance P-like immunoreactivity and contractions induced by capsaicin in the isolated guinea-pig and rat bladder
1989
Effect of NG‐monomethyl l ‐arginine (l ‐NMMA) and NG‐nitro l ‐arginine (l ‐NOARG) on non‐adrenergic non‐cholinergic relaxation in the circular muscle of the human ileum
1991
Relief of Pain following Intravesical Capsaicin in Patients with Hypersensitive Disorders of the Lower Urinary Tract
1993
Effect of omega conotoxin on reflex responses mediated by activation of capsaicin-sensitive nerves of the rat urinary bladder and peptide release from the rat spinal cord
1990
Protection induced by cholecystokinin‐8 (CCK‐8) in ethanol‐induced gastric lesions is mediated via vagal capsaicin‐sensitive fibres and CCKA receptors
1991
Specific motor effects of capsaicin on human jejunum
1988
On the role of NK-2 tachykinin receptors in the mediation of spinal reflex excitability in the rat
1991
Substance P stimulates and inhibits intestinal peristalsis via distinct receptors.
1995
Calcium and capsaicin- induced substance P release from peripheral terminals of primary sensory neurons
1988
Characterization of the apamin- and L-nitroarginine-resistant NANC inhibitory transmission to the circular muscle of guinea-pig colon.
1996
Postnatal development of micturition reflex in rats
1986
Activation of capsaicin-sensitive primary afferents in the rat urinary bladder by compound 48/80: a direct action on sensory nerves?
1992
Analysis of factors involved in determining urinary bladder voiding cycle in urethan-anesthetized rats
1986
Effect of capsaicin pretreatment on regulatory peptides in the rat gastrointestinal tract
1990
Dual effects of clonidine on micturition reflex in urethane anesthetized rats.
1985
Neuropeptides as regulators of airway function: vasoactive intestinal peptide and the tachykinins.
1995
Calcitonin gene-related peptide selectively increases cAMP levels in the guinea-pig ureter
1995
Intravesical Capsaicin for Treatment of Severe Bladder Pain: A Randomized Placebo Controlled Study
1996
Evidence for two indipendent modes of activation of the “efferent” function mediated by peripheral terminals of capsaicin-sensitive sensory neurons by the use of omega conotoxin GVIA, a peptide modulator of neuronal calcium channels
1988
Characterization of the tachykinin neurokinin-2 receptor in the human urinary bladder by means of selective receptor antagonists and peptidase inhibitors.
1993