Citation Impact
Citing Papers
Suppression of Aging in Mice by the Hormone Klotho
2005 StandoutScience
Raised levels of plasma interleukin‐1β in major and postviral depression
2001
A Meta-Analysis of Cytokines in Major Depression
2009 Standout
Targeting the Inflammatory Pathway as a Therapeutic Tool for Major Depression
2014
Th2 cytokine response in Major Depressive Disorder patients before treatment
2006
Dexamethasone-induced effects on lymphocyte distribution and expression of adhesion molecules in treatment-resistant depression
2002
Increased plasma peroxides and serum oxidized low density lipoprotein antibodies in major depression: Markers that further explain the higher incidence of neurodegeneration and coronary artery disease
2010
The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression.
2008
Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
2012
Consensus paper of the WFSBP Task Force on Biological Markers: Biological Markers in Depression
2007
Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis
2001
A detailed examination of cytokine abnormalities in Major Depressive Disorder
2007
Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut
2012
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Assessment of the immune system activity in Iranian patients with Major Depression Disorder (MDD).
2007
Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression
2011
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?
2011
Beyond the serotonin hypothesis: Mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders
2010
Major depressive disorder
2016 Standout
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
2009 Standout
Blood levels of cytokines in elderly patients with major depressive disorder
1998
Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis
2010 Standout
No health without mental health
2007 Standout
High-sensitivity C-reactive protein levels in patients with major depressive disorder and bipolar mania
2006
Increased 8-hydroxy-deoxyguanosine, a marker of oxidative damage to DNA, in major depression and myalgic encephalomyelitis / chronic fatigue syndrome.
2009
Primary dysthymia: A study of several psychosocial, endocrine and immune correlates
1996
Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation
2015 Standout
Cytokines, “Depression Due to A General Medical Condition,” and Antidepressant Drugs
1999
Evidence for an immune response in major depression: A review and hypothesis
1995
The relevance of the in- versus outpatient status for studies on HPA-axis in depression: Spontaneous hypercortisolism is a feature of major depressed inpatients and not of major depression per se
1994
Estrogen receptors and human disease
2006 Standout
T‐helper 1/T‐helper 2 cytokine imbalance and clinical phenotypes of acute‐phase major depression
2007
Biological mechanisms in the relationship between depression and heart disease
2002
Diurnal Cortisol Rhythm as a Predictor of Breast Cancer Survival
2000 Standout
Is Caregiving Hazardous to One's Physical Health? A Meta-Analysis.
2003 Standout
Multiple aberrations in shared inflammatory and oxidative & nitrosative stress (IO&NS) pathways explain the co-association of depression and cardiovascular disorder (CVD), and the increased risk for CVD and due mortality in depressed patients
2010
Fatty acid composition in major depression: decreased ω3 fractions in cholesteryl esters and increased C20:4ω6C20:5ω3 ratio in cholesteryl esters and phospholipids
1996
Different immune patterns in melancholic and non-melancholic major depression
2001
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Cytokines and depression
2002
Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis
2009 Standout
IDO chronic immune activation and tryptophan metabolic pathway: A potential pathophysiological link between depression and obesity
2017
Diurnal variation of plasma cortisol and homovanillic acid in healthy subjects
1996
Childhood and Adolescent Depression: A Review of the Past 10 Years. Part I
1996 Standout
Expert Committee Recommendations Regarding the Prevention, Assessment, and Treatment of Child and Adolescent Overweight and Obesity: Summary Report
2007 Standout
Treatment with interferon-alpha (IFNα) of hepatitis C patients induces lower serum dipeptidyl peptidase IV activity, which is related to IFNα-induced depressive and anxiety symptoms and immune activation
2001
Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
2003 Standout
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression
2011
Association of klotho gene polymorphism with bone density and spondylosis of the lumbar spine in postmenopausal women
2002
Interleukin-1β and tumor necrosis factor-α in children with major depressive disorder or dysthymia
2002
Psychoneuroimmunology of autoimmune disorders
1996
Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation
1997 Standout
Cellular Immunity in Depressed, Conduct Disorder, and Normal Adolescents: Role of Adverse Life Events
1994
Neuroendocrine measures and lymphocyte subsets in depressive illness: Influence of a clinical interview concerning life experiences
1997
Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
2010
Variations of lymphocyte subsets associated with stress in depressive populations
1996
Acute phase proteins in major depression
1997
The Unknown Mechanism of the Overtraining Syndrome
2002
The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
2003 Standout
Enhanced adrenal sensitivity to adrenocorticotrophic hormone (ACTH) is evidence of HPA axis hyperactivity in Alzheimer's disease
1996
Inflammatory Proteins and Depression in the Elderly
2003
Significantly increased expression of T-cell activation markers (interleukin-2 and HLA-DR) in depression: Further evidence for an inflamatory process during that illness
1993
Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association
2022 Standout
The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression
2008
Immunoendocrine aspects of major depression
1995
Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments
2001
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D)
2012
Cytokines sing the blues: inflammation and the pathogenesis of depression
2005 Standout
Α Review on the Acute Phase Response in Major Depression
1993
Regulation of serotonin re-uptake transporter mRNA expression by ovarian steroids in rhesus macaques
1998
Acute Stressors and Cortisol Responses: A Theoretical Integration and Synthesis of Laboratory Research.
2004 Standout
Inflammatory markers and depressed mood in older persons: results from the health, aging and body composition study
2003
Increased serum interleukin-1-receptor-antagonist concentrations in major depression
1995
The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
2012 Standout
The biochemistry and medical significance of the flavonoids
2002 Standout
Elevated levels of acute phase plasma proteins in major depression
1992
Cytokine Production and Treatment Response in Major Depressive Disorder
2000
Cytokine Production and Serum Proteins in Depression
1995
Components of biological variation in plasma haptoglobin: relationships to plasma fibrinogen and immune variables, including interleukin-6 and its receptor
1995
Cytokines, stress, and depressive illness
2002
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Cytokines as mediators of depression: What can we learn from animal studies?
2005
Positive and negative acute phase proteins in affective subtypes
1998
Polymorphisms in the Sclerosteosis/van Buchem Disease Gene (SOST) Region Are Associated with Bone-Mineral Density in Elderly Whites
2004 StandoutNobel
Immune Correlates of Depression
1999
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
Increased 24‐hour urinary cortisol excretion in patients with post‐traumatic stress disorder and patients with major depression, but not h patients with fibromyalgia
1998
The Relationship of Depression and Stressors to Immunological Assays: A Meta-Analytic Review
2001
Indicators of immune activation in major depression
1996
A prospective evaluation of the directionality of the depression–inflammation relationship
2009
Major Depression and Activation of The Inflammatory Response System
1999
Inflammatory markers in major depression and melancholia
2001
Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: Further evidence for an immune response
1994
Stress-induced immune dysfunction: implications for health
2005 Standout
Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy
2013 Standout
Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression
1995
Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects
2011 Standout
Inflammatory and oxidative and nitrosative stress pathways underpinning chronic fatigue, somatization and psychosomatic symptoms
2008
Estrogen Receptor Gene Polymorphisms and the Genetics of Osteoporosis: A HuGE Review
2005
Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
2013
The Neuroendocrinology of Stress: A Never Ending Story
2008 Standout
The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans
2002
Plasma-soluble interleukin-2 and transferrin receptor in schizoprenia and major depression
1995
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
2012 Standout
Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk
2003
The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
2010
Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
2018 Standout
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness
2010 Standout
Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor alpha gene and their relationship to bone mass variation in postmenopausal Italian women
2000
Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry.
2004 Standout
An association between increased serum-soluble interleukin-2 receptors and a disturbance in muscle force in schizophrenic patients
1997
The Human Plasma Proteome
2002 Standout
Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis
2005
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
The effect of chronic treatment with imipramine on the immunoreactivity of animals subjected to a chronic mild stress model of depression
1995
The molecular neurobiology of depression
2008 StandoutNature
Estrogen Actions in the Central Nervous System1
1999 Standout
Effects of antidepressants on the production of cytokines
2002
Can we vaccinate against depression?
2012
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies
2001 Standout
The importance of the ratio of omega-6/omega-3 essential fatty acids
2002 Standout
Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis
2006
Cytokine imbalance in the pathophysiology of major depressive disorder
2007
Clinically Significant Drug Interactions with Newer Antidepressants
2011
Physiology of β-endorphins. A close-up view and a review of the literature
1993
Impact of Depression and Antidepressant Treatment on Heart Rate Variability: A Review and Meta-Analysis
2010 Standout
Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs
1997
Long-lasting effects of (±)3,4-methylene-dioxymethamphetamine (Ecstasy) on serotonin system function in humans
2000
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
2003
In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice
2004
Comparison of Immunological and Endocrinological Markers Associated with Major Depression
2003
Influence of perceived psychological stress and distress on antibody response to low dose rDNA hepatitis B vaccine
1993
The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in Cardiovascular Disease and Other Chronic Diseases
2008 Standout
Pharmacological interventions for somatoform disorders in adults
2014 Standout
Current and Potential Drugs for Treatment of Obesity
1999
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Lower serum zinc in major depression is a sensitive marker of treatment resistance and of the immune/inflammatory response in that illness
1997
Klotho Gene Polymorphisms Associated With Bone Density of Aged Postmenopausal Women
2002
Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression?
1993
Ovarian Steroid Regulation of Tryptophan Hydroxylase mRNA Expression in Rhesus Macaques
1996
Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior
2011
Increased serum soluble CD8 or suppressor/cytotoxic antigen concentrations in depression: Suppressive effects of glucocorticoids
1996
The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System
2000 Standout
Depressive symptoms and production of proinflammatory cytokines by peripheral blood mononuclear cells stimulated in vitro
2006
Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy
2006
Effects of Hypericum perforatum on Levels of 5-Hydroxytryptamine, Noradrenaline and Dopamine in the Cortex, Diencephalon and Brainstem of the Rat
1999
The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression.
2008
Works of C. Vandervorst being referenced
Lack of Association Between Estrogen Receptor Genotypes and Bone Mineral Density, Fracture History, or Muscle Strength in Elderly Women
1999
Coexisting dysregulations of both the sympathoadrenal system and hypothalamic-pituitary-adrenal-axis in melancholia
1991
Decreased serum dipeptidyl peptidase IV activity in major depression
1991
Immune Disturbances during Major Depression: Upregulated Expression of Interleukin-2 Receptors
1990
A multivariate study of simultaneous escape from suppression by dexamethasone of urinary free cortisol, plasma cortisol, adrenocorticotropic hormone and β‐endorphin in melancholic patients
1991
Pituitary and adrenal hormone responsiveness to synachten in melancholic subjects versus subjects with minor depression
1993
Evidence for a systemic immune activation during depression: results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining
1992
Abnormal pituitary function during melancholia: Reduced α-melanocyte-stimulating hormone secretion and increased intact ACTH non-suppression
1991
Disturbances in acute phase plasma proteins during melancholia: Additional evidence for the presence of an inflammatory process during that illness
1992
Depression‐related disturbances in mitogen‐induced lymphocyte responses and interleukin‐1β and soluble interleukin‐2 receptor production
1991
Psychomotor retardation, anorexia, weight loss, sleep disturbances, and loss of energy: Psychopathological correlates of hyperhaptoglobinemia during major depression
1993
Antiphospholipid, antinuclear, epstein-barr and cytomegalovirus antibodies, and soluble interleukin-2 receptors in depressive patients
1991
Absolute Number and Percentage of Circulating Natural Killer, Non-MHC-Restricted T Cytotoxic, and Phagocytic Cells in Unipolar Depression
1994
HPA-Axis hormones and prolactin responses to dextro-fenfluramine in depressed patients and healthy controls
1991