Citation Impact
Citing Papers
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
Effects of an Rb mutation in the mouse
1992 StandoutNature
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Maintenance of functional equivalence during paralogous Hox gene evolution
2000 StandoutNatureNobel
Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169
1990 Standout
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Role for ELOVL3 and Fatty Acid Chain Length in Development of Hair and Skin Function
2004 StandoutNobel
Changing potency by spontaneous fusion
2002 StandoutNature
[52] Simple screening procedure to detect gene targeting events in embryonic stem cells
1993
Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
1995 StandoutNatureNobel
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
1996 StandoutNature
A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene
1991 StandoutNature
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1994 StandoutNature
How were new medicines discovered?
2011 Standout
Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor
1992 StandoutNature
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
1994 StandoutNature
Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6
1992 StandoutNatureNobel
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Visualizing an Olfactory Sensory Map
1996 StandoutNobel
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
Traumatic Brain Injury-Induced Hippocampal Neurogenesis Requires Activation of Early Nestin-Expressing Progenitors
2008
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α
1998 StandoutNobel
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
1993 StandoutNatureNobel
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
Elastin is an essential determinant of arterial morphogenesis
1998 StandoutNature
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 StandoutNatureNobel
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
1996 StandoutNature
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Cut, paste, and save: New approaches to altering specific genes in mice
1989
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
1993 StandoutNobel
Precision of genotyping of Epstein-Barr virus by polymerase chain reaction using three gene loci (EBNA-2, EBNA-3C, and EBER): predominance of type A virus associated with Hodgkin's disease [published erratum appears in Blood 1993 Oct 1;82(7):2268]
1993
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1997 StandoutNobel
HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and Therapy
1995 StandoutScience
Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma
1994 StandoutScience
Isolating gene-corrected stem cells without drug selection
2005 StandoutNobel
Detection of targeted GFP - Hox gene fusions during mouse embryogenesis
1998 StandoutNobel
Altering the Genome by Homologous Recombination
1989 StandoutScienceNobel
Of Flies and Fishes
1994 StandoutScienceNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Functional Role of Type I and Type II Interferons in Antiviral Defense
1994 StandoutScience
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
1998 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
The Purine Path to Chemotherapy
1989 ScienceNobel
A dominant positive and negative selectable gene for use in mammalian cells.
1991 StandoutNobel
Targeting of an inducible toxic phenotype in animal cells.
1988
Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner
1998 StandoutNobel
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
1995 StandoutNobel
In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine
1992
Lethal thalassemia after insertional disruption of the mouse major adult beta-globin gene.
1993 StandoutNobel
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.
1985
Dominant Positive and Negative Selection Using a Hygromycin Phosphotransferase-Thymidine Kinase Fusion Gene
1991
Genetic control of blood pressure and the angiotensinogen locus.
1995 StandoutNobel
The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
2001 StandoutScienceNobel
Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.
1994 StandoutNobel
Genetic Decreases in Atrial Natriuretic Peptide and Salt-Sensitive Hypertension
1995 StandoutScienceNobel
Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination.
1990 StandoutNobel
Reduced growth, abnormal kidney structure, and type 2 (AT 2 ) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT 1A and AT 1B receptors for angiotensin II
1998 StandoutNobel
Works of C U Lambe being referenced
Metabolic activation of 9([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human lymphoblastoid cell lines infected with Epstein-Barr virus
1986
Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information
1987
A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate.
1986
Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus.
1985
2-Amino-6-methoxypurine arabinoside: an agent for T-cell malignancies.
1995
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U
1984