Citation Impact
Citing Papers
Nonclassic Functions of Human Topoisomerase I: Genome-Wide and Pharmacologic Analyses
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2008
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage
1995 StandoutNobel
An autonomous chromatin/DNA-PK mechanism for localized DNA damage signaling in mammalian cells
2013
Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes
1997
SFTG international collaborative study on in vitro micronucleus test
2006
Cell cycle checkpoint signaling through the ATM and ATR kinases
2001 Standout
Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts
2002
Genetic Disorders Associated with Cancer Predisposition and Genomic Instability
1999
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Meiotic DNA replication checkpoint control in fission yeast
1999 StandoutNobel
Folic acid deficiency increases chromosomal instability, chromosome 21 aneuploidy and sensitivity to radiation-induced micronuclei
2005
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
The in vitro micronucleus technique
2000 Standout
The HUman MicroNucleus Project—An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans
1999
Effect of cytochalasin B on the induction of chromosome missegregation by colchicine at low concentrations in human lymphocytes
1999
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Differential Stabilization of Eukaryotic DNA Topoisomerase I Cleavable Complexes by Camptothecin Derivatives
1995 StandoutNobel
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
DNA recombinase activity of eukaryotic DNA topoisomerase I; effects of camptothecin and other inhibitors
1995
Micronuclei induced by aneugens and clastogens in mononucleate and binucleate cells using the cytokinesis block assay
2004
Rho GTPases and signaling networks
1997 Standout
Genotype-Phenotype Relationships in Ataxia-Telangiectasia and Variants
1998
ATM Is Required for IκB Kinase (IKK) Activation in Response to DNA Double Strand Breaks
2001
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2020 Standout
Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I
1993
Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm
1993 StandoutNobel
Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I
1992
SFTG international collaborative study on in vitro micronucleus test
2006
Genome stability is ensured by temporal control of kinetochore–microtubule dynamics
2008
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Sister-chromatid exchange: second report of the Gene-Tox program
1993
The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction
1997
The causes and consequences of genetic heterogeneity in cancer evolution
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IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans
2000 Standout
γH2AX and cancer
2008
Region-specific chromatin decondensation and micronucleus formation induced by 5-azacytidine in human TIG-7 cells
2004
Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU)
1999
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
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2012
Cytokinesis-block micronucleus cytome assay
2007 Standout
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin
1993 StandoutNobel
Muscle development in the four-winged Drosophila and the role of the Ultrabithorax gene
1994 StandoutNobel
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
A critical evaluation of centromeric labeling to distinguish micronuclei induced by chromosomal loss and breakage in vitro
1997
No increase in micronuclei frequency in cultured blood lymphocytes from a group of filling station attendants
1996
Signaling to NF-κB
2004 Standout
What do human micronuclei contain?
2003
The suitability of the micronucleus assay in human lymphocytes as a new biomarker of excision repair
1995
Use of Restriction Endonucleases to Study Relationships between DNA Double-strand Breaks, Chromosomal Aberrations and Other End-points in Mammalian Cells
1988
The Hallmarks of Aging
2013 Standout
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
Sex chromosomes, micronuclei and aging in women
1994
The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene
1995
Effects of Uracil Incorporation, DNA Mismatches, and Abasic Sites on Cleavage and Religation Activities of Mammalian Topoisomerase I
1997 StandoutNobel
The advantages and disadvantages of the cytokinesis-block micronucleus method
1997
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Ataxia-Telangiectasia:Closer to Unraveling the Mystery
1995
Novel roles for A‐type lamins in telomere biology and the DNA damage response pathway
2009
The Saccharomyces cerevisiae RAD9, RAD17, RAD24 and MEC3 Genes Are Required for Tolerating Irreparable, Ultraviolet-Induced DNA Damage
1998 StandoutNobel
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
1991
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
2010
Small GTP-Binding Proteins
2001 Standout
Defective G2 checkpoint function in cells from individuals with familial cancer syndromes.
1995
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells
2014 StandoutNobel
Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring
1996 StandoutNobel
A simple, rapid, and sensitive DNA assay procedure
1980 Standout
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor
2003 Science
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites.
1995 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
Whole chromosome loss is promoted by telomere dysfunction in primary cells
2010
A Gene Controlling Condensation of Heterochromatin in Drosophila melanogaster
1983 Science
Evidence for heterogeneity in heterochromatin of Drosophila melanogaster
1975 Nature
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
Indications for a threshold of chemically‐induced aneuploidy in vitro in human lymphocytes
1995
Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents
2013
ATM Mediates Cytotoxicity of a Mutant Telomerase RNA in Human Cancer Cells
2008 StandoutNobel
diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene
1994
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
DNA Double-Strand Breaks
2002 StandoutNobel
Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know
2003 Standout
Cell lineage relationships in Drosophila melanogaster: The relationships of cuticular to internal tissues
1981
cdc12p, a Protein Required for Cytokinesis in Fission Yeast, Is a Component of the Cell Division Ring and Interacts with Profilin
1997 StandoutNobel
Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM
2004
Conserved microtubule–actin interactions in cell movement and morphogenesis
2003
Targeted Disruption of the Mouse Topoisomerase I Gene by Camptothecin Selection
1996 StandoutNobel
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1998 StandoutScience
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
The dissociation of nuclear and centrosomal division in gnu, a mutation causing giant nuclei in Drosophila
1986 StandoutNobel
Brd4 Is Required for Recovery from Antimicrotubule Drug-induced Mitotic Arrest: Preservation of Acetylated Chromatin
2005
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Sister-chromatid exchanges: A report of the GENE-TOX program
1981
ATAXIA-TELANGIECTASIA AND THE NIJMEGEN BREAKAGE SYNDROME: Related Disorders But Genes Apart
1997
DNA Topoisomerases: Structure, Function, and Mechanism
2001 Standout
Use of the cytokinesis-block micronucleus assay to measure radiation-induced chromosome damage in lymphoblastoid cell lines
2003
Works of C. Tanzarella being referenced
Chromosomal aberrations induced by restriction endonucleases
1985
Modulation of radiation-induced chromosomal damage by inhibitors of DNA repair and flow cytometric analysis in ataxia telangiectasia cells with ‘intermediate radiosensitivity’
1995
The R215W mutation in NBS1 impairs γ-H2AX binding and affects DNA repair: molecular bases for the severe phenotype of 657del5/R215W Nijmegen breakage syndrome patients
2008
Mitotic non-disjunction as a mechanism for in vitro aneuploidy induction by X-rays in primary human cells
1996
Chromosome Nondisjunction and Loss Induced by Protons and X Rays in Primary Human Fibroblasts: Role of Centromeres in Aneuploidy
2001
The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens. Results from two laboratories
1994
Role of Bim in apoptosis induced in H460 lung tumor cells by the spindle poison Combretastatin-A4
2011
Simultaneous inhibition of contractile ring and central spindle formation in mammalian cells treated with cytochalasin B
1998
The Yield of Fission Neutron-induced Chromatid Aberrations in G2-stage Human Lymphocytes: Effect of Caffeine, Hydroxyurea and Cytosine Arabinoside Post-irradiation
1992
In vitro micronucleus test with kinetochore staining: evaluation of test performance
1991
Mitotic indirect non-disjunction in phytohemagglutinin stimulated human lymphocytes
1994
A collaborative study on the improvement of the micronucleus test in cultured human lymphocytes
1992
Effects of 5-azacytidine on the centromeric region of human fibroblasts studied by CREST staining and in situ hybridization on cytokinesis-blocked cells
1996
Cytokinesis-block micronucleus assay with kinetochore detection in colchicine-treated human fibroblasts
1993
Micronuclei, centromere-positive micronuclei and chromosome nondisjunction in cytokinesis blocked human lymphocytes following mitomycin C or vincristine treatment
1997
Topoisomerase II inhibition in mitosis produces numerical and structural chromosomal aberrations in human fibroblasts
1997
The R527H mutation in LMNA gene causes an increased sensitivity to ionizing radiation
2008
Induction of chromosomal aberrations and SCE by camptothecin, and inhibitor of mammalian topoisomerase I
1989
Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells
1999
Hypersensitivity of lymphoblastoid lines derived from ataxia telangiectasia patients to the induction of chromosomal aberrations by etoposide (VP-16)
1993
Effect of l-ethionine on spontaneous and MMC-induced SCEs in G0 and G1 human lymphocytes under liquid-holding recovery conditions
1984
ANALYSIS OF THE CHROMOSOME ABERRATIONS INDUCED BY X-RAYS IN SOMATIC CELLS OF DROSOPHILA MELANOGASTER
1974
Immunofluorescent staining of kinetochores in micronuclei: A new assay for the detection of aneuploidy
1988
Variation with Sex of Irradiation-induced Chromosome Damage in Somatic Cells of Drosophila melanogaster
1974 Nature
Genetic effects of petroleum fuels: II. Analysis of chromosome loss and hyperploidy in peripheral lymphocytes of gasoline station attendants
1998
Comparison of the frequencies of SCEs induced by chemical mutagens in bone-marrow, spleen and spermatogonial cells of mice
1982