Citation Impact
Citing Papers
A Secreted Form of ADAM9 Promotes Carcinoma Invasion through Tumor-Stromal Interactions
2005
Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes
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Interleukin-6 production by human liver (myo)fibroblasts in culture. Evidence for a regulatory role of LPS, IL-1 beta and TNF alpha.
1995
Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.
1998
Localisation and semiquantitative assessment of hepatic procollagen mRNA in primary biliary cirrhosis
1998
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
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Spontaneous Large-Scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H+/K+-ATPase-Reactive TCR Transgenic Mouse
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Redox mechanisms in hepatic chronic wound healing and fibrogenesis
2008
The Transcriptional and DNA Binding Activity of Peroxisome Proliferator-activated Receptor α Is Inhibited by Ethanol Metabolism
2001
Stellate Cell Activation in Alcoholic Pancreatitis
2003
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Thiazolidinediones
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CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
1999
Tissue inhibitors of metalloproteinases in liver fibrosis
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Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone
2003
Mechanisms of alcoholic pancreatitis
2010
Transforming Growth Factor β as a Predictor of Liver and Lung Fibrosis after Autologous Bone Marrow Transplantation for Advanced Breast Cancer
1993
Transforming growth factor-β1 in autoimmune hepatitis: correlation of liver tissue expression and serum levels with disease activity
1998
Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3
2001
Disruption of transforming growth factor-β signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-γ in rat hepatic stellate cells
2006
Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications
2012
Expression of HSP47, a collagen-specific chaperone, in normal and diseased human liver
2005
The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C1 1The authors thank Wanda Delogu and Nadia Navari for skillful technical help, Dr. Roberto G. Romanelli for help in collecting liver biopsy specimens, and Dr. Mario Strazzabosco (Ospedali Riuniti di Bergamo, Italy) for providing part of the tissue samples with primary biliary cirrhosis.
2003
Liver fibrosis
2005 Standout
Pregnane X Receptor Activators Inhibit Human Hepatic Stellate Cell Transdifferentiation In Vitro
2006
Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis
1996
Association of differentially expressed genes with activation of mouse hepatic stellate cells by high-density cDNA mircoarray
2004
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
2005
Review article: omega-3 fatty acids - a promising novel therapy for non-alcoholic fatty liver disease
2010
Neuroprotective Properties of Nitric Oxide
1999
Role of Transforming Growth Factor β in Human Disease
2000 Standout
Mesenchymal cells in the liver – one cell type or two?
2002
Oxidative stress-related molecules and liver fibrosis
2001
Mechanisms of liver fibrosis
2005
Activation of rat hepatic stellate cells leads to loss of glutathion S -transferases and their enzymatic activity against products of oxidative stress
1999
Liver fibrosis – from bench to bedside
2003 Standout
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
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Peroxisome proliferator-activated receptor-β signaling contributes to enhanced proliferation of hepatic stellate cells
2003
Transcriptional Activation of Transforming Growth Factor β1 and Its Receptors by the Kruppel-like Factor Zf9/Core Promoter-binding Protein and Sp1
1998
PI-3 K/AKT and ERK signaling pathways mediate leptin-induced inhibition of PPARγ gene expression in primary rat hepatic stellate cells
2009
Design and validation of a histological scoring system for nonalcoholic fatty liver disease†
2005 Standout
The metabolic syndrome
2010 Standout
Hallmarks of aging: An expanding universe
2023 Standout
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis
2003
Expression of the thrombin receptor in human liver: Up-regulation during acute and chronic injury
1998
Transforming Growth Factor-β Initiates Wound Repair in Rat Liver through Induction of the EIIIA-Fibronectin Splice Isoform
2000
Changes in chemical coding of myenteric neurones in ulcerative colitis
2002
Hepatocellular carcinoma
2012 Standout
Interleukin–10 Controls Neutrophilic Infiltration, Hepatocyte Proliferation, and Liver Fibrosis Induced by Carbon Tetrachloride in Mice
1998
Therapeutic strategies against TGF‐β signaling pathway in hepatic fibrosis
2005
Delayed Induction, Not Impaired Recruitment, of Specific CD8+ T Cells Causes the Late Onset of Acute Hepatitis C
2011 StandoutNobel
DLPC and SAMe prevent α1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione
2006
Adipogenic Transcriptional Regulation of Hepatic Stellate Cells
2004
Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease
2011
Inflammatory bowel disease: cause and immunobiology
2007 Standout
Non-alcoholic fatty liver disease: The mist gradually clears
2008
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
1998 StandoutNobel
Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation.
1995
Omega-3 Fatty Acids Therapy in Children with Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial
2015
Nutritional therapy in alcoholic liver disease
2003
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Calcitonin gene-related peptide: Multiple actions, multiple receptors
1992
Acute Pancreatitis
2016 Standout
Pharmacological agents for NASH
2013
Therapeutic potential of capsaicin-like molecules: Studies in animals and humans
1992
Rosiglitazone for Nonalcoholic Steatohepatitis: One-Year Results of the Randomized Placebo-Controlled Fatty Liver Improvement With Rosiglitazone Therapy (FLIRT) Trial
2008
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Fibrogenic effect of oxidative stress on rat hepatic stellate cells
1998
Transcriptional regulation of hepatic stellate cell activation: Figure 1
2002
Genomic and functional characterization of stellate cells isolated from human cirrhotic livers
2005
On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis
1996
The metabolic syndrome
2005 Standout
Inhibition of Collagen α1(I) Expression by the 5′ Stem-Loop as a Molecular Decoy
2002
The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver
1992
Non-alcoholic fatty liver disease
2021 Standout
Alcoholic liver disease: New insights in pathogenesis lead to new treatments
2000
Acetaldehyde Adducts in Alcoholic Liver Disease
2010
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
The Role of Diet and Nutrient Composition in Nonalcoholic Fatty Liver Disease
2012
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Long-Term Efficacy of Rosiglitazone in Nonalcoholic Steatohepatitis: Results of the Fatty Liver Improvement by Rosiglitazone Therapy (Flirt 2) Extension Trial
2009
Ethanol and Arachidonic Acid Increase α2(I) Collagen Expression in Rat Hepatic Stellate Cells Overexpressing Cytochrome P450 2E1
2000
Diabetes and Atherosclerosis
2002 Standout
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
2004
Iron-induced oxidant stress in alcoholic liver fibrogenesis
2003
Nonalcoholic Steatohepatitis: Summary of An Aasld Single Topic Conference
2003 Standout
Inhibition of the Na+/H+ exchanger reduces rat hepatic stellate cell activity and liver fibrosis: An in vitro and in vivo study
2001
Autocrine release of TGF‐β by portal fibroblasts regulates cell growth
2004
Role of stellate cells in pancreatic fibrogenesis associated with acute and chronic pancreatitis
2006
Mechanisms and Therapy of Hepatic Fibrosis: Report of the Aasld Single Topic Basic Research Conference
2000
Pharmacological aspects of pentoxifylline with emphasis on its inhibitory actions on hepatic fibrogenesis
1997
Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient l-amino acid-defined diet
2004
Hepatocyte Transplantation Activates Hepatic Stellate Cells With Beneficial Modulation of Cell Engraftment in the Rat *
2005
Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells
1996
Adipogenic Phenotype of Hepatic Stellate Cells
2005
Transforming Growth Factor β1 Induces the Expression of α1(I) Procollagen Mrna by A Hydrogen Peroxide–C/Ebpβ–Dependent Mechanism in Rat Hepatic Stellate Cells
1999
Hydrogen peroxide: A link between acetaldehyde-elicited α1(i) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells
2000
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Transforming growth factor-β gene expression in normal and fibrotic rat liver
1997
Pioglitazone Prevents Early-Phase Hepatic Fibrogenesis Caused by Carbon Tetrachloride
2002
Proteome analysis of rat hepatic stellate cells
2000
Effects of Sho–Saiko–To, A Japanese Herbal Medicine, on Hepatic Fibrosis in Rats
1999
Expression and location of Smad2, 4 mRNAs during and after liver fibrogenesis of rats
2006
Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF‐β as major players and therapeutic targets
2006
The pancreatic stellate cell: a star on the rise in pancreatic diseases
2007
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
2010 Standout
Expression of Cellular Prion Protein in Activated Hepatic Stellate Cells
1998
The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
2012
Oxidative stress, KLF6 and transforming growth factor-β up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats
2003
Effect of antioxidants, resveratrol, quercetin, and N -acetylcysteine, on the functions of cultured rat hepatic stellate cells and kupffer cells
1998
Modulation of transforming growth factor β response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts
2000
Transforming Growth Factor β in Tissue Fibrosis
1994 Standout
Advances in Pediatric Nonalcoholic Fatty Liver Disease†
2009
The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
2012 Standout
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
2015 Standout
Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells
2003
Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells
2005
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells
2011 StandoutNobel
Idiopathic pulmonary fibrosis
2011 Standout
Hepatocellular carcinoma pathogenesis: from genes to environment
2006 Standout
Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function
2007
Somatostatin inhibits pro‐inflammatory cytokine secretion from rat hepatic stellate cells
2005
The Na+/H+ exchanger modulates the fibrogenic effect of oxidative stress in rat hepatic stellate cells
1999
Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-α production in cultured macrophage cell lines
2009
Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis
2010 Standout
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
2003
Hepatocellular Carcinoma
2011 Standout
Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?
2020
SERUM TRANSFORMING GROWTH FACTOR-??1 LEVELS IN BONE MARROW TRANSPLANT RECIPIENTS CORRELATE WITH BLOOD CELL COUNTS AND CHRONIC GRAFT-VERSUS-HOST DISEASE1
1999
Chronic liver injury, TGF-β, and cancer
2001
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Peroxisome Proliferator-activated Receptor γ Suppresses Proximal α1(I) Collagen Promoter via Inhibition of p300-facilitated NF-I Binding to DNA in Hepatic Stellate Cells
2005
Anti‐oxidant ebselen causes the resolution of experimentally induced hepatic fibrosis in rats
2001
Aldehydes potentiate α2(I) collagen gene activity by JNK in hepatic stellate cells
2001
The Myofibroblast
2007 Standout
Specific binding of [3H]resiniferatoxin by human and rat preoptic area, locus ceruleus, medial hypothalamus, reticular formation and ventral thalamus membrane preparations
1996
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
Hepatitis C Virus-Replicating Hepatocytes Induce Fibrogenic Activation of Hepatic Stellate Cells
2005
Caffeine Inhibits the Activation of Hepatic Stellate Cells Induced by Acetaldehyde via Adenosine A2A Receptor Mediated by the cAMP/PKA/SRC/ERK1/2/P38 MAPK Signal Pathway
2014
RNA-binding Protein RBMS3 Is Expressed in Activated Hepatic Stellate Cells and Liver Fibrosis and Increases Expression of Transcription Factor Prx1
2007
Liver Fibrogenesis: A New Role for the Renin–Angiotensin System
2005
The Macrolides: Erythromycin, Clarithromycin, and Azithromycin
1999
The endocannabinoid 2‐arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
2007
Pregnenolone-16α-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms
2005
Pharmacological interventions for somatoform disorders in adults
2014 Standout
Nonalcoholic fatty liver disease: an emerging threat to obese and diabetic individuals
2013
Improved Nonalcoholic Steatohepatitis After 48 Weeks of Treatment With the Ppar–γ Ligand Rosiglitazone
2003
The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas
2002
Modulation of transforming growth factor beta receptors of rat lipocytes during the hepatic wound healing response. Enhanced binding and reduced gene expression accompany cellular activation in culture and in vivo.
1994
Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo
2013 Standout
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Mitogenic effect of transforming growth factor-beta 1 on human Ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor.
1993
Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver. Up-regulation during in vitro activation and in hepatic tissue repair.
1996
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells
1994 StandoutNobel
Mechanisms of alcohol‐induced hepatic fibrosis
2006
Pharmacotherapy for Nonalcoholic Fatty Liver Disease
2015
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Dyslipidemia in Patients with Nonalcoholic Fatty Liver Disease
2012
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
The selective cyclooxygenase‐2 inhibitor SC‐236 reduces liver fibrosis by mechanisms involving non‐parenchymal cell apoptosis and PPARγ activation
2005
Human myofibroblastlike cells obtained by outgrowth are representative of the fibrogenic cells in the liver
1995
Transforming Growth Factors β1 and α in Chronic Liver Disease
1991
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Anti‐adipogenic regulation underlies hepatic stellate cell transdifferentiation
2006
Transforming growth factor-β1 regulates platelet-derived growth factor receptor β subunit in human liver fat-storing cells
1995
Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver.
1994
Antipsychotics for acute and chronic pain in adults
2013
No Significant Effects of Ethyl-Eicosapentanoic Acid on Histologic Features of Nonalcoholic Steatohepatitis in a Phase 2 Trial
2014
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
An adipocentric view of liver fibrosis and cirrhosis.
2004
Involvement of cAMP-PKA pathway in adenosine A1 and A2A receptor-mediated regulation of acetaldehyde-induced activation of HSCs
2015
Role of hepatic stellate cells in the pathogenesis of portal hypertension.
2002
Nonalcoholic Fatty Liver Disease
2015 Standout
Role of Transcriptional Factors in Stellate Cell Activation
1999
Secretion of 72 kDa type IV collagenase/gelatinase by cultured human lipocytes. Analysis of gene expression, protein synthesis and proteinase activity
1992
Review article: omega‐3 fatty acids – a promising novel therapy for non‐alcoholic fatty liver disease
2009
HEPATIC FIBROSIS: Molecular Mechanisms and Drug Targets
2004
Sp1 and Sp3 Transcription Factors Mediate Malondialdehyde-induced Collagen α1(I) Gene Expression in Cultured Hepatic Stellate Cells
2002
Current status of novel antifibrotic therapies in patients with chronic liver disease
2011
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
Works of C. Surrenti being referenced
Colonic vasoactive intestinal polypeptide in ulcerative colitis
1993
Undulin Rna and Protein Expression in Normal and Fibrotic Human Liver
1994
Calcitonin gene-related peptide increases the production of glycosaminoglycans but not of collagen type I and III in cultures of rat fat-storing cells
1991
Regulation of Undulin Synthesis and Gene Expression in Human Fat-Storing Cells by Acetaldehyde and Transforming Growth Factor-β1: Comparison with Fibronectin
1994
Prolonged n‐3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non‐alcoholic fatty liver disease: a pilot study
2006
Peroxisome proliferator-activated receptor γ transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells
2000
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
2002
Acetaldehyde-protein adducts, but not lactate and pyruvate, stimulate gene transcription of collagen and fibronectin in hepatic fat-storing cells
1993
Oxidative stress stimulates proliferation and invasiveness of hepatic stellate cells via a MMP2‐mediated mechanism†
2005
Phannacokinetics of azithromycin in patients with impaired hepatic function
1993
Alcohol induced hepatic fibrosis: Role of acetaldehyde
2007
Collagen type I synthesized by pancreatic periacinar stellate cells (PSC) co-localizes with lipid peroxidation-derived aldehydes in chronic alcoholic pancreatitis
2000
Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells
1994
Transforming growth factors beta 1 and beta 2 are differentially expressed in fibrotic liver disease.
1991
Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis
1990
Cellular localization of type I III and IV procollagen gene transcripts in normal and fibrotic human liver.
1990
Sensory Nerves and Neuropeptides in Gastroenterology
1991
ACETALDEHYDE INDUCES C-FOS AND C-JUN PROTO-ONCOGENES IN FAT-STORING CELL CULTURES THROUGH PROTEIN KINASE C ACTIVATION
1994
Human hepatic stellate cells express class I alcohol dehydrogenase and aldehyde dehydrogenase but not cytochrome P4502E1
1998
Helicobacter pylori cagPathogenicity Island Is Associated with Reduced Expression of Interleukin-4 (IL-4) mRNA and Modulation of the IL-4δ2 mRNA Isoform in Human Gastric Mucosa
2003
Substance P and vasoactive intestinal polypeptide but not calcitonin gene-related peptide concentrations are reduced in patients with moderate and severe ulcerative colitis.
1998
Neutrophil–Derived Superoxide Anion Induces Lipid Peroxidation and Stimulates Collagen Synthesis in Human Hepatic Stellate Cells: Role of Nitric Oxide
1997
Levosulpiride in functional dyspepsia: a multicentric, double-blind, controlled trial.
1997