Citation Impact
Citing Papers
Assembly of a Functional HCV Glycoprotein Heterodimer
2007
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Hepatitis C Virus E2-CD81 Interaction Induces Hypermutation of the Immunoglobulin Gene in B Cells
2005
Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus
2009
Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus andHost
2006
NS2 Protein of Hepatitis C Virus Interacts with Structural and Non-Structural Proteins towards Virus Assembly
2011
Expression of HIV-1 Envelope Glycoproteins by Semliki Forest Virus Vectors
1993
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate
2003
Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: Putative CD81 binding region 1 is not involved in CD81 binding
2008
Characterization of Hepatitis C Virus Particle Subpopulations Reveals Multiple Usage of the Scavenger Receptor BI for Entry Steps
2012
Cell Culture Systems for Hepatitis C Virus
2013
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Reconstitution of Hepatitis C Virus Envelope Glycoproteins into Liposomes as a Surrogate Model to Study Virus Attachment
2002
Topology of hepatitis C virus envelope glycoproteins
2003
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Functional Features of Hepatitis C Virus Glycoproteins for Pseudotype Virus Entry into Mammalian Cells
2000
Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo
2008
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A
2017
The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule
2010
Cell Entry of Hepatitis C Virus Requires a Set of Co-receptors That Include the CD81 Tetraspanin and the SR-B1 Scavenger Receptor
2003
A model for the hepatitis C virus envelope glycoprotein E2
2000
High Density Lipoproteins Facilitate Hepatitis C Virus Entry through the Scavenger Receptor Class B Type I
2005
Structural Features of Envelope Proteins on Hepatitis C Virus-like Particles as Determined by Anti-envelope Monoclonal Antibodies and CD81 Binding
2002
Hepatitis C Virus Is Primed by CD81 Protein for Low pH-dependent Fusion
2011
Interaction between hepatitis C virus proteins and host cell factors
2002 StandoutNobel
HCV E2 core structures and mAbs: something is still missing
2014
Hepatitis C Virus Continuously Escapes From Neutralizing Antibody and T-Cell Responses During Chronic Infection In Vivo
2006 StandoutNobel
Cell entry of hepatitis C virus
2006
The past, present and future of neutralizing antibodies for hepatitis C virus
2014
Non-random Escape Pathways from a Broadly Neutralizing Human Monoclonal Antibody Map to a Highly Conserved Region on the Hepatitis C Virus E2 Glycoprotein Encompassing Amino Acids 412–423
2014
Cellular glycosaminoglycans and low density lipoprotein receptor are involved in hepatitis C virus adsorption
2002
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
High Density Lipoprotein Inhibits Hepatitis C Virus-neutralizing Antibodies by Stimulating Cell Entry via Activation of the Scavenger Receptor BI
2006
The Transmembrane Domains of Hepatitis C Virus Envelope Glycoproteins E1 and E2 Play a Major Role in Heterodimerization
2000
The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development
2014
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Proteomics computational analyses suggest that hepatitis C virus E1 and pestivirus E2 envelope glycoproteins are truncated class II fusion proteins
2003
Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells
2006 StandoutNobel
Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1
2017
Challenges for structure-based HIV vaccine design
2009
Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry
2013
HIV as the cause of AIDS
1996 StandoutNobel
Structure–function analysis of hepatitis C virus envelope glycoproteins E1 and E2
2014
Kinetics of HCV envelope proteins’ interaction with CD81 large extracellular loop
2005
Characterization of host‐range and cell entry properties of the major genotypes and subtypes of hepatitis C virus†
2005
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry
2009
Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33
2006
The tetraspanin web modulates immune-signalling complexes
2005
Comparative immunogenicity analysis of modified vaccinia Ankara vectors expressing native or modified forms of hepatitis C virus E1 and E2 glycoproteins
2004
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus
2002
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Characterization of Pseudotype VSV Possessing HCV Envelope Proteins
2001
Characterisation of the differences between hepatitis C virus genotype 3 and 1 glycoproteins
2003
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
Mapping of a Conformational Epitope Shared between E1 and E2 on the Serum-derived Human Hepatitis C Virus Envelope
2003
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
Functional hepatitis C virus envelope glycoproteins
2004
Human Monoclonal Antibodies to a Novel Cluster of Conformational Epitopes on HCV E2 with Resistance to Neutralization Escape in a Genotype 2a Isolate
2012
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity
2002
Replication of hepatitis C virus
2007 StandoutNobel
Transmembrane Domains of Hepatitis C Virus Envelope Glycoproteins: Residues Involved in E1E2 Heterodimerization and Involvement of These Domains in Virus Entry
2006
The B-cell receptor of a hepatitis C virus (HCV)–associated non-Hodgkin lymphoma binds the viral E2 envelope protein, implicating HCV in lymphomagenesis
2001
Hepatitis C Virus E2 Has Three Immunogenic Domains Containing Conformational Epitopes with Distinct Properties and Biological Functions
2004
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Evaluation of Hepatitis C Virus Glycoprotein E2 for Vaccine Design: an Endoplasmic Reticulum-Retained Recombinant Protein Is Superior to Secreted Recombinant Protein and DNA-Based Vaccine Candidates
2000 StandoutNobel
Mutations within a Conserved Region of the Hepatitis C Virus E2 Glycoprotein That Influence Virus-Receptor Interactions and Sensitivity to Neutralizing Antibodies
2010
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
1996
Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus
2007
Structure and Function of the Hepatitis C Virus Envelope Glycoproteins E1 and E2: Antiviral and Vaccine Targets
2016 StandoutNobel
Replication of hepatitis C virus
2000
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
CD81-Dependent Binding of Hepatitis C Virus E1E2 Heterodimers
2003
The role of neutralizing antibodies in hepatitis C virus infection
2011
Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion
2015
Binding of Hepatitis C Virus E2 Glycoprotein to CD81 Does Not Correlate with Species Permissiveness to Infection
2000
Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus
2008
A Library of Infectious Hepatitis C Viruses with Engineered Mutations in the E2 Gene Reveals Growth-Adaptive Mutations That Modulate Interactions with Scavenger Receptor Class B Type I
2016
Infectious Hepatitis C Virus Pseudo-particles Containing Functional E1–E2 Envelope Protein Complexes
2003
Cooperativity in Virus Neutralization by Human Monoclonal Antibodies to Two Adjacent Regions Located at the Amino Terminus of Hepatitis C Virus E2 Glycoprotein
2012
CD81 Is Required for Hepatitis C Virus Glycoprotein-Mediated Viral Infection
2004 StandoutNobel
Characterization of the Envelope Glycoproteins Associated with Infectious Hepatitis C Virus
2010
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Hepatitis C Virus Entry
2013
Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization
2014 StandoutNobel
Unexpected Structural Features of the Hepatitis C Virus Envelope Protein 2 Ectodomain
2014
Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1
1994
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Scavenger Receptor BI and BII Expression Levels Modulate Hepatitis C Virus Infectivity
2007
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2
2010
Broadly Neutralizing Immune Responses against Hepatitis C Virus Induced by Vectored Measles Viruses and a Recombinant Envelope Protein Booster
2012 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Hepatitis C virus cell entry: role of lipoproteins and cellular receptors
2009
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Biogenesis of hepatitis C virus envelope glycoproteins
2001
An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies
2005
Diverse Hepatitis C Virus Glycoproteins Mediate Viral Infection in a CD81-Dependent Manner
2004 StandoutNobel
L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virus
2003
CD81 is an entry coreceptor for hepatitis C virus
2004
Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection
2005
Identification of Amino Acid Residues in CD81 Critical for Interaction with Hepatitis C Virus Envelope Glycoprotein E2
2000
A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1
2019 StandoutNobel
Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus
2017 StandoutNobel
Alphavirus-based expression vectors: strategies and applications.
1996 StandoutNobel
Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis
2006
In vitro selection of a neutralization-resistant hepatitis C virus escape mutant
2008
Structural and Antigenic Definition of Hepatitis C Virus E2 Glycoprotein Epitopes Targeted by Monoclonal Antibodies
2013
Functional Analysis of Hepatitis C Virus Envelope Proteins, Using a Cell-Cell Fusion Assay
2006
Characterization of Hepatitis C Virus (HCV) and HCV E2 Interactions with CD81 and the Low-Density Lipoprotein Receptor
2000
Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein
2008
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Hepatitis C virus entry: potential receptors and their biological functions
2006
A Single Injection of Recombinant Measles Virus Vaccines Expressing Human Immunodeficiency Virus (HIV) Type 1 Clade B Envelope Glycoproteins Induces Neutralizing Antibodies and Cellular Immune Responses to HIV
2003
Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission
2010
Characterization of Infectious Retroviral Pseudotype Particles Bearing Hepatitis C Virus Glycoproteins
2004 StandoutNobel
Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
2009
Binding of Hepatitis C Virus-Like Particles Derived from Infectious Clone H77C to Defined Human Cell Lines
2002
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Incorporation of Hepatitis C Virus E1 and E2 Glycoproteins: The Keystones on a Peculiar Virion
2014
Characterization of Functional Hepatitis C Virus Envelope Glycoproteins
2004
CD81 Is a Central Regulator of Cellular Events Required for Hepatitis C Virus Infection of Human Hepatocytes
2008
Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Proteins Incorporated into Infectious Virions
2010
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Directed differentiation of human embryonic stem cells into functional hepatic cells†
2007
A Conserved Gly436-Trp-Leu-Ala-Gly-Leu-Phe-Tyr Motif in Hepatitis C Virus Glycoprotein E2 Is a Determinant of CD81 Binding and Viral Entry
2006
Human Monoclonal Antibodies That Inhibit Binding of Hepatitis C Virus E2 Protein to CD81 and Recognize Conserved Conformational Epitopes
2000
Antigenic Variation within the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120: Effects on Chemokine Receptor Utilization
2001
Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses
2006
Neutralizing Monoclonal Antibodies against Hepatitis C Virus E2 Protein Bind Discontinuous Epitopes and Inhibit Infection at a Postattachment Step
2011
Expressionof Unmodified Hepatitis C Virus Envelope Glycoprotein-Coding SequencesLeads to Cryptic Intron Excision and Cell Surface Expression of E1/E2Heterodimers Comprising Full-Length and Partially DeletedE1
2003
Recognition of Native Hepatitis C Virus E1E2 Heterodimers by a Human Monoclonal Antibody
2002
Hepatitis C Virus Envelope Protein E2 Binds to CD81 of Tamarins
2000
Identification of the Hepatitis C Virus E2 Glycoprotein Binding Site on the Large Extracellular Loop of CD81
2002
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Hepatitis C Virus Glycoproteins Interact with DC-SIGN and DC-SIGNR
2003 StandoutNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Hepatitis C Virus NS2 Coordinates Virus Particle Assembly through Physical Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
2010
The C-terminal region of the hepatitis C virus E1 glycoprotein confers localization within the endoplasmic reticulum
1999
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity
2009 StandoutNobel
Genetic and Functional Characterization of the N-Terminal Region of the Hepatitis C Virus NS2 Protein
2013 StandoutNobel
Diverse CD81 Proteins Support Hepatitis C Virus Infection
2006 StandoutNobel
Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Glycoproteins
2005
Accumulation of B Lymphocytes with a Naive, Resting Phenotype in a Subset of Hepatitis C Patients
2003 StandoutNobel
Cellular receptors for viruses: links to tropism and pathogenesis
2000
Different Domains of CD81 Mediate Distinct Stages of Hepatitis C Virus Pseudoparticle Entry
2006
Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies
2008
Coexpression of hepatitis C virus envelope proteins E1 and E2 in cis improves the stability of membrane insertion of E2
2001
Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees
2000
Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding
2006
The Acidic Domain of Hepatitis C Virus NS4A Contributes to RNA Replication and Virus Particle Assembly
2010
Interaction of Hepatitis C Virus-Like Particles and Cells: a Model System for Studying Viral Binding and Entry
2002
Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity
2009
Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1
2012
Functional Characterization of Intracellular and Secreted Forms of a Truncated Hepatitis C Virus E2 Glycoprotein
2000
The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein
2007
Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody
2012
Binding of the Hepatitis C Virus E2 Glycoprotein to CD81 Is Strain Specific and Is Modulated by a Complex Interplay between Hypervariable Regions 1 and 2
2003
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Contribution of the charged residues of hepatitis C virus glycoprotein E2 transmembrane domain to the functions of the E1E2 heterodimer
2005
Chemokine receptors and human immunodeficiency virus infection
1998
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of C Shotton being referenced
Functional Analysis of Cell Surface-Expressed Hepatitis C Virus E2 Glycoprotein
1999
Characterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120
1993
Identification and characterization of monoclonal antibodies specific for polymorphic antigenic determinants within the V2 region of the human immunodeficiency virus type 1 envelope glycoprotein
1995
Change in tropism upon immune escape by human immunodeficiency virus
1995
Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: role of glycosylation in the correct folding of the V1/V2 domain
1995
Truncated gp120 envelope glycoprotein of human immunodeficiency virus 1 elicits a broadly reactive neutralizing immune response
2002
Characterization of Hepatitis C Virus E2 Glycoprotein Interaction with a Putative Cellular Receptor, CD81
1999