Standout Papers
- Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis. (1983)
- Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product. (1984)
- Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils. (1984)
Citation Impact
Citing Papers
Prospective Randomized Trial of Docetaxel Versus Best Supportive Care in Patients With Non–Small-Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy
2000 Standout
Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations
2013 Standout
Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer
2008 Standout
Meta-Analysis of Concomitant Versus Sequential Radiochemotherapy in Locally Advanced Non–Small-Cell Lung Cancer
2010 Standout
Protectin D1 Is Generated in Asthma and Dampens Airway Inflammation and Hyperresponsiveness
2007
The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene
1997 Standout
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Design and Synthesis of Inhibitors of Folate Dependent Enzymes as Antitumor Agents
1993
Dietary Supplementation with Fish Oil in Ulcerative Colitis
1992
Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids
2010
A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution
2004
The Effect of Dietary Supplementation with n—3 Polyunsaturated Fatty Acids on the Synthesis of Interleukin-1 and Tumor Necrosis Factor by Mononuclear Cells
1989 Standout
The biology and management of non-small cell lung cancer
2018 StandoutNature
First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
2014 Standout
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Chronic Rejection in Experimental Cardiac Transplantation: Studies in the Lewis‐F344 Model
1993
Dietary fish oil and olive oil supplementation in patients with Rheumatoid Arthritis clinical and immunologic effects
1990
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
2008 Standout
Nanocarriers as an emerging platform for cancer therapy
2007 Standout
Coronary heart disease: seven dietary factors
1991 Standout
Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells
2003 Standout
Lung cancer: current therapies and new targeted treatments
2016 Standout
Neutrophils and immunity: challenges and opportunities
2006 Standout
Cardiovascular Effects of n-3 Fatty Acids
1988 Standout
n−3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases
2006 Standout
Protective Effect of Fish Oil Supplementation on Exercise-Induced Bronchoconstriction in Asthma
2006
Fish Intake, Contaminants, and Human Health
2006 Standout
[14] Detection of protein-protein interactions by protein fragment complementation strategies
2000
Growth-inhibitory effects of 5,10-dideazatetrahydrofolic acid on variant murine L1210 and human CCRF-CEM leukemia cells with different membrane-transport characteristics for (anti)folate compounds
1991
Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition
2001 StandoutNobel
Brain Cell and Tissue Recovery in Rats Made Deficient in n-3 Fatty Acids by Alteration of Dietary Fat
1989 StandoutNobel
Malignant Gliomas in Adults
2008 Standout
Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways
2001
Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced nonsmall cell lung carcinoma
2001
Eicosanoids and cancer
2010 Standout
Enhanced production of platelet-activating factor in stimulated rat leukocytes pretreated with triacsin C, a novel acyl-CoA synthetase inhibitor
1992 StandoutNobel
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
1995 Standout
Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase
1991
A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED TRIAL OF FISH OIL IN PSORIASIS
1988
10-formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): A potent inhibitor of glycinamide ribonucleotide transformylase
1997
The Docosatriene Protectin D1 Is Produced by TH2 Skewing and Promotes Human T Cell Apoptosis via Lipid Raft Clustering
2005
Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor‐1 mRNA in cultured human endothelial cells
1995 StandoutNobel
Polyunsaturated fatty acids and inflammation
2006
Angiogenesis as a therapeutic target
2005 StandoutNature
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Advances in Malignant Mesothelioma
2005 Standout
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
Folate status and the safety profile of antifolates
2002
Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.
1991
Isolation and partial characterization of a human alveolar macrophage-derived neutrophil-activating factor.
1985
A Phase I Study of Pemetrexed, Carboplatin, and Concurrent Radiotherapy in Patients with Locally Advanced or Metastatic Non–Small Cell Lung or Esophageal Cancer
2007
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
High Fat Diets Varying in Ratios of Polyunsaturated to Saturated Fatty Acid and Linoleic to Linolenic Acid: A Comparison of Rat Neural and Red Cell Membrane Phospholipids
1986
Alterations in human leukocyte function induced by ingestion of eicosapentaenoic acid
1986
Metabolic effects and kill of human T-cell leukemia by 5-deazaacyclotetrahydrofolate, a specific inhibitor of glycineamide ribonucleotide transformylase.
1992
Chemokines
1997 Standout
Leukotriene B4 Modulates Phospholipid Methylation and Chemotaxis in Human Polymorphonuclear Leukocytes
1990
The biological chemistry of folate receptors
1992
Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma
2003 Standout
Leukotriene B5 is formed in human neutrophils after dietary supplementation with icosapentaenoic acid.
1985
Polyunsaturated fatty acids and inflammation
2005
Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing
2000
Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: possible mechanisms
1990
Diagnosis and Treatment of Recurrent High-Grade Astrocytoma
2006
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Linolenate-derived Polyunsaturated Fatty Acids and Prevention of Atherosclerosis
2009
Effect of Dietary Enrichment with Eicosapentaenoic and Docosahexaenoic Acids on in Vitro Neutrophil and Monocyte Leukotriene Generation and Neutrophil Function
1985 StandoutNobel
Metabolism and effects on platelet function of the purified eicosapentaenoic and docosahexaenoic acids in humans.
1985
Glomerular prostaglandins, angiotensin II, and nonsteroidal anti-inflammatory drugs
1986
Randomized Phase III Trial of Pemetrexed Versus Docetaxel in Patients With Non–Small-Cell Lung Cancer Previously Treated With Chemotherapy
2004 Standout
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Optical study of the formation of pyrrolo[2,3-d]pyrimidine-based fluorescent nanoaggregates
2013
Structures of apo and complexed Escherichia coli glycinamide ribonucleotide transformylase.
1992
Insertion of an intracisternal A particle within the 5'-regulatory region of a gene encoding folate-binding protein in L1210 leukemia cells in response to low folate selection. Association with increased protein expression.
1992 StandoutNobel
Multitargeted Antifolate LY231514 as First-Line Chemotherapy for Patients With Advanced Non–Small-Cell Lung Cancer: A Phase II Study
1999
Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study
2009
Fish oil inhibits development of atherosclerosis in rhesus monkeys.
1987
Combination of Antiangiogenic Therapy With Other Anticancer Therapies: Results, Challenges, and Open Questions
2005
Inflammatory Mechanisms in Obesity
2011 Standout
Novel ? ? 3-derived local mediators in anti-inflammation and resolution
2004
The Effects of Dietary α-Linolenic Acid on the Composition of Nerve Membranes, Enzymatic Activity, Amplitude of Electrophysiological Parameters, Resistance to Poisons and Performance of Learning Tasks in Rats
1989 StandoutNobel
Total synthesis of leukotriene B5
1983 StandoutNobel
Acylation of docosahexaenoic acid into phospholipids by intact human neutrophils
1986
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
1999 Standout
In Situ Selection of Lead Compounds by Click Chemistry: Target-Guided Optimization of Acetylcholinesterase Inhibitors
2005 StandoutNobel
The eicosanoids and their biochemical mechanisms of action
1989
Clinical and Pharmacokinetic Phase I Study of Multitargeted Antifolate (LY231514) in Combination With Cisplatin
1999
A novel folate transport activity in human mesothelioma cell lines with high affinity and specificity for the new-generation antifolate, pemetrexed.
2002
Secretory products of macrophages.
1987 Standout
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes. The role of lyso-PAF disposal and free arachidonic acid
1990
The Differential Efficacy of Pemetrexed According to NSCLC Histology: A Review of Two Phase III Studies
2009
Increased thromboxane a2 generation and altered membrane fatty acid composition in platelets from patients with active angina pectoris
1986
A simple process for the purification of arachidonic acid
1984 StandoutNobel
Fish-Oil Fatty Acid Supplementation in Active Rheumatoid Arthritis
1987
Resolvins
2002
Works of C Shih being referenced
Cellular pharmacology of MTA: a correlation of MTA-induced cellular toxicity and in vitro enzyme inhibition with its effect on intracellular folate and nucleoside triphosphate pools in CCRF-CEM cells.
1999
Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in human T98G glioblastoma multiforme xenografts.
2001
Synthesis and biological activity of nor- and homo-5,10-dideazatetrahydrofolic acid
1992
Synthesis and biological activity of 2-desamino and 4-deoxy analogs of 5,10-dideazatetrahydrofolic acid (DDATHF)
1993
A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors.
1994
Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.
1984 StandoutNobel
LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
1997
The 6S- and 6R-Diastereomers of 5, 10-Dideaza-5, 6, 7, 8-tetrahydrofolate Are Equiactive Inhibitors of de Novo Purine Synthesis
1989
Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis.
1983 StandoutNobel
Role of thymidylate synthase in the antitumor activity of the multitargeted antifolate, LY231514.
1999
Augmentation of the therapeutic activity of lometrexol -(6-R)5,10-dideazatetrahydrofolate- by oral folic acid.
1996
Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.
1984 StandoutNobel