Standout Papers
Citation Impact
Citing Papers
Consensus Statement of the Movement Disorder Society on Tremor
2008 Standout
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
2020 Standout
International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors
2002 Standout
Characterization and distribution of binding sites for [3H]-SR 141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain
1996
The role of diazepam binding inhibitor and its processing products at mitochondrial benzodiazepine receptors: Regulation of steroid biosynthesis
1991
Evidence that nitric oxide mediates the cyclic GMP response to synaptic activity in the rat superior cervical ganglion
1992 StandoutNobel
Long-term depression in cerebellar Purkinje neurons results from coincidence of nitric oxide and depolarization-induced Ca2+ transients
1995 StandoutNobel
The ependyma: A protective barrier between brain and cerebrospinal fluid
1995
Identification, characterization and potent antitumor activity of ECO-4601, a novel peripheral benzodiazepine receptor ligand
2007
Natural products: An evolving role in future drug discovery
2011 Standout
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
2004 Standout
Nitric oxide synthase: Irreversible inhibition by L-N -Nitroarginine in brain and
1991
Development of antibody-based assays for high throughput discovery and mechanistic study of antiviral agents against yellow fever virus
2020 StandoutNobel
Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System
1999 Standout
Design, synthesis, and structure–activity relationships of novel tetracyclic compounds as peripheral benzodiazepine receptor ligands
2004
An Inducible Functional Peripheral Benzodiazepine Receptor in Mitochondria of Steroidogenic Granulosa Cells*
1991
Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
2006
The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: From pathology to imaging
2006
The Role of Immune and Inflammatory Mechanisms in ALS
2011
Design, synthesis and structure–activity relationship of novel tricyclic benzimidazolone derivatives as potent 18 kDa translocator protein (TSPO) ligands
2012
Peduncular 'Rubral' Tremor and Dopaminergic Denervation
1995
Privileged scaffolds for library design and drug discovery
2010 Standout
Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: An imaging tool for glial cells in the brain
2004
Fe(ii), Ru(ii) and Re(i) complexes of endotopic, sterically non-hindering, U-shaped 8,8′-disubstituted-3,3′-biisoquinoline ligands: syntheses and spectroscopic properties
2007 StandoutNobel
The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development
2005
The adolescent brain and age-related behavioral manifestations
2000 Standout
Amyotrophic lateral sclerosis
2011 Standout
Effect of the benzodiazepines diazepam, des-N-methyldiazepam and midazolam on corticosteroid biosynthesis in bovine adrenocortical cells in vitro; location of site of action
1989
Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study
2004
The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
2003 Standout
Nitric oxide, a novel neuronal messenger
1992 Standout
Imaging Translocator Protein as a Biomarker of Neuroinflammation in Dementia
2017
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
2007 Standout
[11C]DAA1106: radiosynthesis and in vivo binding to peripheral benzodiazepine receptors in mouse brain
2003
Peripheral-type benzodiazepine receptor density and in vitro tumorigenicity of glioma cell lines
2004
Regulation of the Acute Production of Steroids in Steroidogenic Cells*
1996 Standout
Mitochondria as a Pharmacological Target
2002
Amygdaloid central nucleus lesions and cholinergic blockade attenuate the response of the renal peripheral benzodiazepine receptor to stress
1993
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations
1988 Standout
The mitochondrial permeability transition fromin vitroartifact to disease target
2006
Does GFAP mRNA and mitochondrial benzodiazepine receptor binding detect serotonergic neuronal degeneration in rat?
1994
The Peripheral Benzodiazepine Receptors: A Review
2000
Identification and structure–activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors
2010
The mitochondrial benzodiazepine receptor: Evidence for association with the voltage-dependent anion channel (VDAC)
1992
Lanthanide luminescence for functional materials and bio-sciences
2009 Standout
Hypoxia of the Renal Medulla — Its Implications for Disease
1995 Standout
Peripheral-type benzodiazepine receptors
1993
Peripheral-Type Benzodiazepine/Diazepam Binding Inhibitor Receptor: Biological Role in Steroidogenic Cell Function*
1993
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Membrane lipids: where they are and how they behave
2008 Standout
Systemic injection of kainic acid: Gliosis in olfactory and limbic brain regions quantified with [3H]PK 11195 binding autoradiography
1990
Modulatory action of benzodiazepines on human term placental steroidogenesis in vitro
1989
Neurosteroid biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides
2009
Reversing the direction in a light-driven rotary molecular motor
2010 StandoutNobel
The mitochondrial permeability transition
1995 Standout
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
2008 Standout
Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein
2008
Binding characteristics of SSR180575, a potent and selective peripheral benzodiazepine ligand
2003
Peripheral benzodiazepine binding sites in Alzheimer's disease frontal and temporal cortex
1991
STRESS AND THE DEVELOPING LIMBIC–HYPOTHALAMIC–PITUITARY–ADRENAL AXIS
1998
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Protein-Protein Interactions Mediate Mitochondrial Cholesterol Transport and Steroid Biosynthesis
2006
The Overexpression of Bax Produces Cell Death upon Induction of the Mitochondrial Permeability Transition
1998 Standout
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
2020 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
The chemistry of recently isolated naturally occurring quinazolinone alkaloids
2006 Standout
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands.
1993
Multiple sites of action for anxiogenic drugs: Behavioural, electrophysiological and biochemical correlations
1984
Peripheral-type benzodiazepines inhibit calcium channels and aldosterone production in adrenal glomerulosa cells.
1993
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
1991 Standout
Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells.
1990
Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus
1997 Standout
A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus
1985 Science
The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.
1986
Covalently Linked Acceptor−Donor Systems Based on Isoquinoline N-oxide Acceptor: Photoinduced Electron Transfer Produces Dual-Channel Luminescent Systems that Evolve Chemically to Photohydroxylation of the Aromatic Donor
2003
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Inflammation as a central mechanism in Alzheimer's disease
2018 Standout
Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO
2018
The mitochondrial permeability transition pore and its role in cell death
1999 Standout
Diazepam binding inhibitor (DBI): A peptide with multiple biological actions
1991
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
Chemical reagents in photoaffinity labeling
1995
Benzodiazepines inhibit transport-related oxygen consumption in thick ascending limb
1988
The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis.
1990
Hormone-stimulated steroidogenesis is coupled to mitochondrial benzodiazepine receptors. Tropic hormone action on steroid biosynthesis is inhibited by flunitrazepam
1991
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Diazepam inhibits potassium-induced aldosterone secretion in adrenal glomerulosa cell
1986
Ischemic Cell Death in Brain Neurons
1999 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone.
1994
Imaging Brain Inflammation with [11C]PK11195 by PET and Induction of the Peripheral-Type Benzodiazepine Receptor after Transient Focal Ischemia in Rats
2007
Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier.
1992
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Diazepam-binding inhibitor (DBI)-processing products, acting at the mitochondrial DBI receptor, mediate adrenocorticotropic hormone-induced steroidogenesis in rat adrenal gland.
1992
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
The use of a plus-maze to measure anxiety in the mouse
1987 Standout
THE MITOCHONDRIAL DEATH/LIFE REGULATOR IN APOPTOSIS AND NECROSIS
1998 Standout
Isolation and cloning of a voltage-dependent anion channel-like Mr 36,000 polypeptide from mammalian brain.
1992
Benzodiazepine- and barbiturate-interactions with GABAA receptor responses on lactotrophes
1986
A Peripheral Benzodiazepine Receptor Targeted Agent for In Vitro Imaging and Screening
2006
Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo.
2002
The proapoptotic benzodiazepine Bz-423 affects the growth and survival of malignant B cells.
2003
A Novel Benzodiazepine Compound Inhibits Yellow Fever Virus Infection by Specifically Targeting NS4B Protein
2016
Mitochondrial benzodiazepine receptors regulate steroid biosynthesis.
1989
Passing Two Strings through the Same Ring Using an Octahedral Metal Center as Template: A New Synthesis of [3]Rotaxanes
2009 StandoutNobel
PET of peripheral benzodiazepine binding sites in the microgliosis of Alzheimer's disease.
1995
The peripheral‐type benzodiazepine receptor: a protein of mitochondrial outer membranes utilizing porphyrins as endogenous ligands
1987
Benzodiazepine Receptors and Their Relationship to the Treatment of Epilepsy
1986
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
2006 Standout
Nitric oxide synthases in mammals
1994 Standout
Works of C. Renault being referenced
Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-(1-methylpropyl)-3 isoquinolinecarboxamide
1983
Photoaffinity labeling of peripheral-type benzodiazepine-binding sites.
1987
Opposite effects of two ligands for peripheral type benzodiazepine binding sites, PK 11195 and RO5-4864, in a conflict situation in the rat
1985
Modulation of voltage-operated, but not receptor-operated, calcium channels in the rabbit aorta by PK 11195, an antagonist of peripheral-type benzodiazepine receptors.
1986
Autoradiographic localization of peripheral benzodiazepine binding sites in the cat brain with [3H]PK 11195
1984
Histidine modification with diethylpyrocarbonate induces a decrease in the binding of an antagonist, PK 11195, but not of an agonist, R05–4864, of the peripheral benzodiazepine receptors
1984
Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamide
1983 Standout
Partial Purification and Pharmacology of Peripheral-Type Benzodiazepine Receptors
1987
Electrophysiological and pharmacological characterization of peripheral benzodiazepine receptors in a guinea pig heart preparation
1984
4-Amino-6-chloro-2-piperazinopyrimidines with selective affinity for .alpha.2-adrenoceptors
1986
PK 11195, an antagonist of peripheral type benzodiazepine receptors, modulates BAY K8644 sensitive but not β- or H2-receptor sensitive voltage operated calcium channels in the guinea pig heart
1986
"Peripheral type" benzodiazepine binding sites in rat adrenals: binding studies with [3H]PK 11195 and autoradiographic localization.
1983
Stereoselective inhibition of the binding of [3H]PK 11195 to peripheral-type benzodiazepine binding sites by a quinolinepropanamide derivative
1986
Labelling of “Peripheral‐Type” Benzodiazepine Binding Sites in the Rat Brain By Using [3H]PK 11195, an Isoquinoline Carboxamide Derivative: Kinetic Studies and Autoradiographic Localization
1983
Opposite effects of an agonist, R05-4864, and an antagonist, PK 11195, of the peripheral type benzodiazepine binding sites on audiogenic seizures in DBA/2J mice
1984
Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]R05-4864 and [3H]PK 11195, by thermodynamic studies
1983
Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart
1985
In vivo labelling in several rat tissues of ‘peripheral type’ benzodiazepine binding sites
1984
Characterization of peripheral type benzodiazepine binding sites in human and rat platelets by using [3H]PK 11195. Studies in hypertensive patients
1984
Characterization of solubilized “peripheral type” benzodiazepine binding sites from rat adrenals by using [3H]PK 11195, an isoquinoline carboxamide derivative
1985