Citation Impact
Citing Papers
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Mature mainstream TCR alpha beta+CD4+ thymocytes expressing L-selectin mediate "active tolerance" in the nonobese diabetic mouse.
1998
Kinetics of Negative and Positive Selection in the Thymus
1991
Regulatory T Cells
2000 StandoutNobel
Characterization of Vβ‐bearing cells in athymic (nu/nu) mice suggests an extrathymic pathway for T cell differentiation
1990
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2004 StandoutNature
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Inactivation of Notch1 Impairs VDJβ Rearrangement and Allows pre-TCR-Independent Survival of Early αβ Lineage Thymocytes
2002
Regulation of T cell production in T cell receptor transgenic mice
1993
The organization of mature T-cell pools
1998
Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
1991
An Alternatively Spliced C. elegans ced-4 RNA Encodes a Novel Cell Death Inhibitor
1996 StandoutNobel
Thymic selection revisited: how essential is it?
2003
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
What is the role of regulatory T cells in transplantation tolerance?
1999
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.
1998
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
1991
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
1998
T cell homeostasis: Keeping useful T cells alive and live T cells useful
2005
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
1991 StandoutNobel
Natural CD4 CD25+ regulatory T cells control the burst of superantigen-induced cytokine production: the role of IL-10
2002
Quantitative and Qualitative Assessment of Human Immunodeficiency Virus Type 1 (HIV‐1)–Specific CD4+T Cell Immunity togagin HIV‐1–Infected Individuals with Differential Disease Progression: Reciprocal Interferon‐γ and Interleukin‐10 Responses
2001
Towards an integrated view of thymopoiesis
1991
Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
2012
Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells
1989 StandoutNatureNobel
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Lymphocyte life-span and memory
1994 Science
Recent thymic emigrants are distinct from most medullary thymocytes
1997
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells
1988 StandoutNobel
The adult T-cell receptor 5-chain is diverse and distinct from that of fetal thymocytes
1988 Nature
Heterogeneity among DN1 Prothymocytes Reveals Multiple Progenitors with Different Capacities to Generate T Cell and Non-T Cell Lineages
2004
Virus-specific CD8+ T-cell memory determined by clonal burst size
1994 StandoutNatureNobel
Immunological Memory
1993
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Thymocyte development is normal in CTLA-4-deficient mice
1997 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
Thymic Anlage Is Colonized by Progenitors Restricted to T, NK, and Dendritic Cell Lineages
2005
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
Peripheral Selection of the T Cell Repertoire
1991 Science
Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus
2001
A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity
2009
Kinetics of mature T-cell development in the thymus.
1990
Self-Nonself Discrimination by T Cells
1990 Science
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Diversity of immunoglobulin expression in leukaemic cells resembling B-lymphocyte precursors
1981 Nature
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Naive and memory T cells show distinct pathways of lymphocyte recirculation.
1990
Epstein–Barr virus transforms precursor B cells even before immunoglobulin gene rearrangements
1984 StandoutNatureNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Receptor-stimulated death pathway is opened by antigen in mature T cells.
1991
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.
1981
Contribution of Receptor Editing to the Antibody Repertoire
2001 Science
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Cutting Edge: In Contrast to Effector T Cells, CD4+CD25+FoxP3+ Regulatory T Cells Are Highly Susceptible to CD95 Ligand- but Not to TCR-Mediated Cell Death
2005
IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells
2004
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas
1997
T CELL MEMORY
1998
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+CD8−CD3+Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7
1999 StandoutNobel
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Alpha/beta T-cell antigen receptor gene and protein expression occurs at early stages of thymocyte differentiation.
1988 StandoutNobel
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Homeostasis of Peripheral CD4+ T Cells: IL-2Rα and IL-2 Shape a Population of Regulatory Cells That Controls CD4+ T Cell Numbers
2002
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Absence of Programmed Death Receptor 1 Alters Thymic Development and Enhances Generation of CD4/CD8 Double-Negative TCR-Transgenic T Cells
2003 StandoutNobel
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
The kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells.
1991
High-Level Replication of Human Immunodeficiency Virus in Thymocytes Requires NF-κB Activation through Interaction with Thymic Epithelial Cells
1999 StandoutNobel
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Activation events during thymic selection.
1992
Regulation of Thymus Size by Competition for Stromal Niches among Early T Cell Progenitors
2004
Turnover of naive- and memory-phenotype T cells.
1994
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors
1988 StandoutNatureNobel
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance
1999 StandoutNobel
Mature Mainstream TCRαβ+CD4+ Thymocytes Expressing L-Selectin Mediate “Active Tolerance” in the Nonobese Diabetic Mouse
1998
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection.
1988
Apoptosis in AIDS
1993 StandoutScienceNobel
Regulation of T-cell receptor gene expression in human T-cell development.
1985 StandoutNobel
Phenotypic heterogeneity and cellular origins of T cell malignancies
1981
Antigen-specific peripheral shaping of the natural regulatory T cell population
2008
Continuous Activation of Autoreactive CD4+ CD25+ Regulatory T Cells in the Steady State
2003
Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1
1994 StandoutNobel
Works of C Pénit being referenced
Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression.
1993
Phenotype analysis of cycling and postcycling thymocytes: Evaluation of detection methods for BrdUrd and surface proteins
1993
Control of prothymocyte proliferation by thymic accessory cells
1987
In vivo dynamics of CD4–8– thymocytes. Proliferation, renewal and differentiation of different cell subsets studied by DNA biosynthetic labeling and surface antigen detection
1988
Accumulation of bromodeoxyuridine‐labeled cells in central and peripheral lymphoid organs: minimal estimates of prodution and turnover rates of mature lymphocytes
1990
Study of the thymocyte cell cycle by bivariate analysis of incorporated bromodeoxyuridine and DNA content
1990
Positive selection is an early event in thymocyte differentiation: high TCR expression by cycling immature thymocytes precedes final maturation by several days
1990
Acute lymphoblastic leukemia with pre-B-cell characteristics
1979
Cell proliferation and thymocyte subset reconstitution in sublethally irradiated mice: compared kinetics of endogenous and intrathymically transferred progenitors.
1989
Relationships between terminal transferase expression, stem cell colonization, and thymic maturation in the avian embryo: studies in thymic chimeras resulting from homospecific and heterospecific grafts.
1985
Interleukin 7 induces preferential expansion of V beta 8.2+CD4-8- and V beta 8.2+CD4+8- murine thymocytes positively selected by class I molecules.
1994
Endogenous granulocyte-macrophage colony-stimulating factor is involved in IL-1- and IL-7-induced murine thymocyte proliferation.
1994
In vivo T cell response to viral superantigen. Selective migration rather than proliferation
1996
T cell deletion induced by chronic infection with mouse mammary tumor virus spares a CD25-positive, IL-10-producing T cell population with infectious capacity.
1997
Cell expansion and growth arrest phases during the transition from precursor (CD4-8-) to immature (CD4+8+) thymocytes in normal and genetically modified mice.
1995
Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes
2002
Production, selection, and maturation of thymocytes with high surface density of TCR.
1994
Terminal deoxynucleotidyl transferase in acute lymphoblastic leukemias and chronic T cell proliferations
1977
Cell proliferation and differentiation in the fetal and early postnatal mouse thymus.
1989
Sequential events in thymocyte differentiation and thymus regeneration revealed by a combination of bromodeoxyuridine DNA labeling and antimitotic drug treatment.
1988
In vivo thymocyte maturation. BUdR labeling of cycling thymocytes and phenotypic analysis of their progeny support the single lineage model.
1986