Standout Papers
- The product of the retroviral transforming gene v-myb is a truncated version of the protein encoded by the cellular oncogene c-myb (1983)
- Molecular cloning of the avian myelocytomatosis virus genome and recovery of infectious virus by transfection of chicken cells (1981)
- Site-specific mutagenesis of avian erythroblastosis virus: erb-B is required for oncogenicity (1983)
- Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses (1978)
- Avian Retroviruses That Cause Carcinoma and Leukemia: Identification of Nucleotide Sequences Associated with Pathogenicity (1980)
- The genome and the intracellular RNAs of avian myeloblastosis virus (1981)
- Site-specific mutagenesis of avian erythroblastosis virus: v-erb-A is not required for transformation of fibroblasts (1983)
- Coordinate regulation of myelomonocytic phenotype by v-myb and v-myc. (1986)
- Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells (1980)
Citation Impact
Citing Papers
On the origin of the genes for neoplasia: G.H.A. Clowes memorial lecture.
1974 StandoutNobel
Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line
1982 Nature
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
1991
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
The glioma-amplified sequence 41 gene (GAS41) is a direct Myb target gene
2004
The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene
1989
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
1989 StandoutNobel
Viral myb oncogene encodes a sequence-specific DNA-binding activity
1988 Nature
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
1989 StandoutNatureNobel
Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells
1989 StandoutNatureNobel
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Virus-specific RNAs in cells infected by avian myelocytomatosis virus and avian erythroblastosis virus: Modes of oncogene expression
1981 StandoutNobel
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
Structure of the protein encoded by the chicken proto-oncogene c-myb.
1986 StandoutNobel
Mapping unintegrated avian sarcoma virus DNA: Termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA
1978 StandoutNobel
A new avian erythroblastosis virus, AEV-H, carries erbB gene responsible for the induction of both erythroblastosis and sarcomas
1983
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
1983 StandoutNature
Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia
1984 Nature
The biosynthesis of oncovirus proteins
1978
Expression of cellular oncogenes during embryonic and fetal development of the mouse.
1984
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Specific integration of REV proviruses in avian bursal lymphomas
1981 Nature
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus
1984 StandoutNatureNobel
Expression of endogenous avian myeloblastosis virus information in different chicken cells
1980
Identification and characterization of the protein encoded by the human c-myb proto-oncogene.
1986
The membrane glycoprotein encoded by the retroviral oncogene v-erb-B is structurally related to tyrosine-specific protein kinases.
1984 StandoutNobel
Proposal for Naming Host Cell-Derived Inserts in Retrovirus Genomes
1981 StandoutNobel
An appraisal of the application of recombinant DNA techniques to chromosome defects
1985
c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock.
1988
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates.
1978 StandoutNobel
Cell-free translation of avian erythroblastosis virus RNA
1980
Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor state
1981 StandoutNobel
RAV-1 insertional mutagenesis: disruption of the c-myb locus and development of avian B-cell lymphomas
1989
Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues
1985 Nature
Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB.
1988 StandoutNobel
Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells
1978 StandoutNobel
THE MOLECULAR GENETICS OF CELLULAR ONCOGENES
1984
Avian erythroblastosis virus produces two mRNA's
1980
DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants
1985
Rapid induction of B-cell lymphomas: insertional activation of c-myb by avian leukosis virus
1988
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion
1981
Isolation of the proto-oncogene c-myb from D. melanogaster
1985 StandoutNobel
Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma.
1984 StandoutNobel
Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas
1982
In vitro translation of avian erythroblastosis virus RNA: Identification of two major polypeptides
1980
Analysis of unintegrated avian RNA tumor virus double-stranded DNA intermediates
1978
Specific RNA sequences and gene products of MC29 avian acute leukemia virus
1978
The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related
1983 StandoutNatureNobel
Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene
1982
Restriction enzyme analysis of partially transformation-defective mutants of acute leukemia virus MC29
1982
Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation
1979 Nature
Phosphorylation of specific sites in the gag-myc polyproteins encoded by MC29-type viruses correlates with their transforming ability.
1982
Developmental regulation of c-myb in normal myeloid progenitor cells.
1985
Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation
1988
Transforming activity of DNA of chemically transformed and normal cells
1980 Nature
Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues
1982
Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.
1982
RNA and protein encoded by MH2 virus: evidence for subgenomic expression of v-myc
1983
Activation of transcription by v-myb: evidence for two different mechanisms.
1989
Recovery of myc-specific sequences by a partially transformation-defective mutant of avian myelocytomatosis virus, MC29, correlates with the restoration of transforming activity.
1982
Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by the chicken c-myb gene
1984 StandoutNobel
Mouse c-myc Oncogene Is Located on Chromosome 15 and Translocated to Chromosome 12 in Plasmacytomas
1982 Science
A normal cell protein similar in structure and function to the avian sarcoma virus transforming gene product.
1979
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product
1980 StandoutNatureNobel
Studies of the Human c- myb Gene and Its Product in Human Acute Leukemias
1986 Science
Identification of nuclear proteins encoded by viral and cellular myc oncogenes
1983 StandoutNatureNobel
Molecular cloning and characterization of the chicken gene homologous to the transforming gene of rous sarcoma virus
1981
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses
1970 StandoutNatureNobel
Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells.
1984
Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element
1982 Nature
Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation.
1988
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
1983 StandoutNatureNobel
Avian acute leukemia virus OK 10: analysis of its myc oncogene by molecular cloning
1983
Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc
1984 StandoutNatureNobel
Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus
1982 StandoutNobel
Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia
1985 StandoutScienceNobel
Transcription of c-onc Genes c-rasKi and c-fms During Mouse Development
1983
Cells transformed by avian myelocytomatosis virus strain CMII contain a 90K gag-related protein
1979
Avian myeloblastosis virus RNA is terminally redundant: Implications for the mechanism of retrovirus replication
1977
Replicating, differentiated macrophages can serve as in vitro targets for transformation by avian myeloblastosis virus
1981
Comparative tryptic peptide mapping studies suggest a role in cell transformation for the gag-related protein of avian erythroblastosis virus and avian myelocytomatosis virus strains CMII and MC29.
1980
Characteristics of two new avian tumor virus subgroups
1969
Avian acute leukemia viruses MC29 and MH2 share specific RNA sequences: Evidence for a second class of transforming genes
1979
Differences between the Ribonucleic Acids of Transforming and Nontransforming Avian Tumor Viruses
1970
Two virus-specific rna species are present in cells transformed by defective leukemia virus OK10
1981
DNA and RNA from Uninfected Vertebrate Cells Contain Nucleotide Sequences Related to the Putative Transforming Gene of Avian Myelocytomatosis Virus
1979 StandoutNobel
Reversibility of differentiation and proliferative capacity in avian myelomonocytic cells transformed by tsE26 leukemia virus.
1987
A second c-myb protein is translated from an alternatively spliced mRNA expressed from normal and 5'-disrupted myb loci.
1989
Nuclear Compartmentalization of the v-myb Oncogene Product
1985
Orientation of the v-erb-B gene product in the plasma membrane.
1986 StandoutNobel
Virus-specific DNA in the cytoplasm of avian sarcoma virus-infected cells is a precursor to covalently closed circular viral DNA in the nucleus
1978
Subcellular localization of the v-erb-B protein, the product of a transforming gene of avian erythroblastosis virus
1984 StandoutNobel
Antibodies to the evolutionarily conserved amino-terminal region of the v-myb-encoded protein detect the c-myb protein in widely divergent metazoan species.
1986
Human c-myb protooncogene: nucleotide sequence of cDNA and organization of the genomic locus.
1986
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.
1983 StandoutNobel
Identification of a form of the avian erythroblastosis virus erb-B gene product at the cell surface
1984 Nature
The erbB gene of avian erythroblastosis virus is a member of the src gene family
1983
Analysis of cellular integration sites in avian sarcoma virus infected duck embryo cells
1979
Recombinants between endogenous and exogenous avian tumor viruses: role of the C region and other portions of the genome in the control of replication and transformation
1980
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Hu- ets -1 and Hu- ets -2 Genes Are Transposed in Acute Leukemias with (4;11) and (8;21) Translocations
1986 Science
Drosophila and vertebrate myb proteins share two conserved regions, one of which functions as a DNA-binding domain.
1987
Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene
1982 Nature
Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene
1985 StandoutScience
Nucleotide sequence of cDNA clones of the murine myb proto-oncogene.
1985
B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo
1985 StandoutScienceNobel
Characterization of the transforming gene of Fujinami sarcoma virus.
1980
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein
1978 StandoutNobel
A single amino acid substitution in v-erbB confers a thermolabile phenotype to ts167 avian erythroblastosis virus-transformed erythroid cells.
1986
Uninfected avian cells contain structurally unrelated progenitors of viral sarcoma genes
1980 Nature
Two types of target cells for transformation with avian myelocytomatosis virus
1973
RAPID ONCOGENESIS IN VIVO BY CHICKEN RETROVIRUS OK 10
1978
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
1976 StandoutNatureNobel
Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro
1985
The product of the avian erythroblastosis virus erbB locus is a glycoprotein
1983 StandoutNobel
Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene.
1989
Orientation of the v-erb-B Gene Product in the Plasma Membrane
1986 StandoutNobel
Isolation and biochemical characterization of partially transformation-defective mutants of avian myelocytomatosis virus strain MC29: localization of the mutation to the myc domain of the 110,000-dalton gag-myc polyprotein
1982
Activation of the c- myb Locus by Viral Insertional Mutagenesis in Plasmacytoid Lymphosarcomas
1984 Science
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas
1982 StandoutNatureNobel
The vertebrate homolog of the putative transforming gene of avian myelocytomatosis virus: Characteristics of the DNA locus and its RNA transcript
1980 StandoutNobel
Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues
1982
Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas.
1983
Characterization of the sequence-specific interaction of mouse c-myb protein with DNA.
1990
c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor
1985
Proteins specified by avian erythroblastosis virus: coding region localization and identification of a previously undetected erb-B polypeptide.
1982 StandoutNobel
Molecular cloning of avian myelocytomatosis virus (MC29) transforming sequences.
1981
Analysis of cells transformed by defective leukemia virus OK10: Production of noninfectious particles and synthesis of Pr76gag and an additional 200,000-dalton protein
1980
Isolation of monoclonal antibodies specific for products of avian oncogene myb.
1984 StandoutNobel
Avian leukemia viruses interaction with their target cells in vivo and in vitro
1978
Insertion and truncation of c-myb by murine leukemia virus in a myeloid cell line derived from cultures of normal hematopoietic cells
1987
Association of gag-myc proteins from avian myelocytomatosis virus wild-type and mutants with chromatin.
1982
Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses
1978 StandoutNobel
Defectiveness of avian myelocytomatosis virus MC29: Isolation of long-term nonproducer cultures and analysis of virus-specific polypeptide synthesis
1977
Differences in sequences encoding the carboxyl-terminal domain of the epidermal growth factor receptor correlate with differences in the disease potential of viral erbB genes.
1986
Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.
1983 StandoutNobel
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
1987 Standout
The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain.
1987
Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29
1982 StandoutNobel
Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbb protein
1985
Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus
1981 Nature
Generation of altered transcripts by retroviral insertion within the c-myb gene in two murine monocytic leukemias
1987
In vitro transformation of lymphoid cells by Abelson murine leukemia virus.
1975 StandoutNobel
Mammalian cell transformation by a murine retrovirus vector containing the avian erythroblastosis virus erbB gene
1986
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules
1980 StandoutNobel
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis
1981 StandoutNature
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
Temperature-sensitive mutants of MH2 avian leukemia virus that map in the v-mil and the v-myc oncogene respectively.
1986
Subgenomic mRNA in OK10 Defective Leukemia Virus-Transformed Cells
1982
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
1987 Standout
Transforming gene product of Rous sarcoma virus phosphorylates tyrosine
1980 Standout
Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus
1980
Nucleotide sequence of chicken c-myb complementary DNA and implications for myb oncogene activation
1986 Nature
Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29
1983 Nature
Expression of c-myc RNA in bursal lymphoma cell lines: Identification of c-myc-encoded proteins by hybrid-selected translation
1983
Induction of angiosarcoma by a c-erbB transducing virus
1985
A Single Amino Acid Substitution in v-erbB Confers a Thermolabile Phenotype to ts167 Avian Erythroblastosis Virus-Transformed Erythroid Cells
1986
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
1985 StandoutNatureNobel
Restriction endonuclease mapping of the DNA of Rous-Associated virus 0 reveals extensive homology in structure and sequence with avian sarcoma virus DNA
1981
Works of C. Moscovici being referenced
Tripartite structure of the avian erythroblastosis virus E26 transforming gene
1983 Nature
Transformation of chick fibroblast cultures with avian myeloblastosis virus
1969
Fujinami sarcoma virus: An avian RNA tumor virus with a unique transforming gene
1980
Size and genetic content of virus-specific RNA in myeloblasts transformed by Avian Myeloblastosis Virus (AMV)
1981
Studies on single foci of hematopoietic cells transformed by avian myeloblastosis virus
1970
The defectiveness of Mill Hill 2, a carcinoma-inducing avian oncovirus
1978
The pathogenicity and defectiveness of PRCII: A new type of avian sarcoma virus
1981
Effects of genetic cellular resistance on cell transformation and virus replication in chicken hematopoietic cell cultures infected with avian myeloblastosis virus (BAI-A)
1968
Response of hemopoietic cells to avian acute leukemia viruses: Effects on the differentiation of the target cells
1979
Isolation of complementary DNA unique to the genome of avian myeloblastosis virus (AMV)
1980
The origin of chicken hematopoietic colonies as assayed in semisolid agar
1975
A Quantitative Assay for Avian Myeloblastosis Virus.
1967
The oncogenic effects of nontransforming viruses from avian myeloblastosis virus.
1969
Analysis of the src gene of sarcoma viruses generated by recombination between transformation-defective mutants and quail cellular sequences
1979
Focus assay and defectiveness of avian myeloblastosis virus
1975
Transformation-Defective Mutant of Avian Myeloblastosis Virus That Is Temperature Sensitive for Production of Transforming Protein p45v-myb
1985
Coordinate regulation of myelomonocytic phenotype by v-myb and v-myc.
1986 StandoutNobel
Restitution of fibroblast-transforming ability in srcdeletion mutants of avian sarcoma virus during animal passage
1979
The genome and the intracellular RNAs of avian myeloblastosis virus
1981 StandoutNobel
Acute leukemia viruses E26 and avian myeloblastosis virus have related transformation-specific RNA sequences but different genetic structures, gene products, and oncogenic properties
1982
Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses
1978 StandoutNobel
Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells
1980 StandoutNobel
Replication of avian sarcoma viruses in chicken macrophages
1974
Genetic structure of avian myeloblastosis virus, released from transformed myeloblasts as a defective virus particle
1980
Leukemic Transformation with Avian Myeloblastosis Virus: Present Status
1975
Molecular cloning of the avian myelocytomatosis virus genome and recovery of infectious virus by transfection of chicken cells
1981 StandoutNobel
Continuous tissue culture cell lines derived from chemically induced tumors of Japanese quail
1977
Site-specific mutagenesis of avian erythroblastosis virus: erb-B is required for oncogenicity
1983 StandoutNobel
Proviral-activated c-erbB is leukemogenic but not sarcomagenic: characterization of a replication-competent retrovirus containing the activated c-erbB
1988
The product of the retroviral transforming gene v-myb is a truncated version of the protein encoded by the cellular oncogene c-myb
1983 StandoutNobel
Characterization of the hemopoietic target cells for the avian leukemia virus E26
1983
Susceptibility and resistance of chicken macrophages to avian RNA tumor viruses
1975
A study of plaque formation with avian RNA tumor viruses
1976
Site-specific mutagenesis of avian erythroblastosis virus: v-erb-A is not required for transformation of fibroblasts
1983 StandoutNobel
Avian Retroviruses That Cause Carcinoma and Leukemia: Identification of Nucleotide Sequences Associated with Pathogenicity
1980 StandoutNobel
Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript.
1986
Colony formation by chicken hematopoietic cells and virus‐induced myeloblasts
1973
Chapter 16 Tissue Culture of Avian Hematopoietic Cells
1974
Myeloid and erythroid neoplastic responses to avian defective leukemia viruses in chickens and in quail
1981
Isolation and characterization of a temperature-sensitive mutant of avian myeloblastosis virus.
1983
Avian Oncovirus Mill Hill No. 2: Pathogenicity in Chickens<xref ref-type="fn" rid="fn2">2</xref>
1979