Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.
2001
Guidelines for the welfare and use of animals in cancer research
2010 Standout
Synthesis, characterization, activities, cell uptake and DNA binding of trinuclear complex: [{trans-PtCl(NH3)}2μ-{trans-Pt(NH3)(2-hydroxypyridine)-(H2N(CH2)6NH2)2]Cl4
2005
The use of polymeric platinum(IV) prodrugs to deliver multinuclear platinum(II) drugs with reduced systemic toxicity and enhanced antitumor efficacy
2012
Circular dichroism study of the irreversibility of conformational changes induced by polyamine-linked dinuclear platinum compounds
2002
Chiral separation of substituted phenylalanine analogues using chiral palladium phosphine complexes with enantioselective liquid–liquid extraction
2010 StandoutNobel
Ovarian cancer: strategies for overcoming resistance to chemotherapy
2003
Cisplatin: mode of cytotoxic action and molecular basis of resistance
2003 Standout
Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies
2008 Standout
Clinical and pharmacological phase I study with accelerated titration design of a daily times five schedule of BBR3464, a novel cationic triplatinum complex
2000
Phase II study of BBR 3464 as treatment in patients with sensitive or refractory small cell lung cancer
2006
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging
2006 Standout
Technical considerations for studying cancer metastasis in vivo
1997
The development of platinum compounds and their possible combination
2006
Health Benefits of Moringa oleifera
2014
Dissemination and growth of cancer cells in metastatic sites
2002 Standout
Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes
2005 Standout
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
The resurgence of platinum-based cancer chemotherapy
2007 Standout
Developing new metal-based therapeutics: challenges and opportunities
2007
Phase II studies of BBR3464, a novel tri-nuclear platinum complex, in patients with gastric or gastro-oesophageal adenocarcinoma
2004
Increased sensitivity to the platelet‐derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF‐BB‐mediated signaling and STI571‐induced Akt inactivation
2006
Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity
2004 Standout
New immunosuppressants with potential implication in multiple sclerosis
2004
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
The biology and function of fibroblasts in cancer
2016 Standout
Neuroblastoma: biological insights into a clinical enigma
2003 Standout
Anticancer activity of osmium metalla-rectangles
2010
Tissue distribution, antitumour activity and in vivo apoptosis induction by MEN10755 in nude mice
2001
Principles of bioactive lipid signalling: lessons from sphingolipids
2008 Standout
Redox homeostasis: The Golden Mean of healthy living
2016
Mononuclear Fe(ii)-N4Py complexes in oxidative DNA cleavage: structure, activity and mechanism
2010 StandoutNobel
A phase II trial of oral tegafur and uracil plus cisplatin in patients with inoperable nonsmall cell lung cancer
1995
Nanocarriers for delivery of platinum anticancer drugs
2013
DNA Interstrand Cross-links of the Novel Antitumor Trinuclear Platinum Complex BBR3464
2002
Molecular mechanisms of cisplatin resistance
2011 Standout
Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro
2014
A phase II trial of ZD0473 in platinum-pretreated ovarian cancer
2002
Are analysts doing method validation in liquid chromatography?
2014
An update on satraplatin: the first orally available platinum anticancer drug
2000
Targeting multidrug resistance in cancer
2006 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Preclinical Perspectives on Platinum Resistance
2000
Areneruthenium complexes as anticancer agents
2009
Cellular processing of platinum anticancer drugs
2005 Standout
The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells
1999
Direct In Vivo Xenograft Tumor Model for Predicting Chemotherapeutic Drug Response in Cancer Patients
2008
Bis-phenanthroline copper(ii) phthalate complexes are potent in vitro antitumour agents with ‘self-activating’ metallo-nuclease and DNA binding properties
2010
Retention of activity by the new generation platinum agent AMD0473 in four human tumour cell lines possessing acquired resistance to oxaliplatin
2002
Bioorganometallic chemistry—from teaching paradigms to medicinal applications
2008 Standout
Antitumor activity of erlotinib (OSI-774, Tarceva) alone or in combination in human non-small cell lung cancer tumor xenograft models
2004
Structural consequences of a 3′ → 3′ DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex
2009
Excursions in polynuclear platinum DNA binding
2010
Platinum‐based anticancer agents: Innovative design strategies and biological perspectives
2003
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
Neuroblastoma
2007 Standout
Tumour-inhibiting platinum complexes—state of the art and future perspectives
2003
Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma1
2006
Cellular pharmacology of polynuclear platinum anti-cancer agents
1999
Synthetic metallomolecules as agents for the control of DNA structure
2006
Metal-based anticancer chemotherapeutic agents
2014
Pancreatic Cancer
2010 Standout
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
Cisplatin in cancer therapy: Molecular mechanisms of action
2014 Standout
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Soluble Extract from Moringa oleifera Leaves with a New Anticancer Activity
2014
New metal complexes as potential therapeutics
2003
A matrix metalloproteinase expressed on the surface of invasive tumour cells
1994 StandoutNature
Fibroblasts in cancer
2006 Standout
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
2004 Standout
Structure and function of “metalloantibiotics”
2003
The anti-angiogenic basis of metronomic chemotherapy
2004 Standout
Current and future potential roles of the platinum drugs in the treatment of ovarian cancer
2001
Metabolic basis of the synergistic antitumor activities of 5-fluorouracil and cisplatin in rodent tumor models in vivo
1993
The status of platinum anticancer drugs in the clinic and in clinical trials
2010 Standout
New Developments and Approaches in the Platinum Arena
2000
The cellular interaction of 5-fluorouracil and cisplatin in a human colon carcinoma cell line
1996
Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells
2002 Standout
Biological Consequences of Trinuclear Platinum Complexes: Comparison of [{trans-PtCl(NH3)2}2μ-(trans-Pt(NH3)2(H2N(CH2)6-NH2)2)]4+ (BBR 3464) with Its Noncovalent Congeners
2005
Characterization of brain and bone-metastasizing clones selected from an ethylnitrosourea-induced rat mammary carcinoma
1994
Current status of the development of trans-platinum antitumor drugs
2000
An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential
2000
In vivo studies of a platinum(ii) metallointercalator
2008
Ligand exchange reactions of [Re2(μ-OR)3(CO)6]− (R = H, Me) with sulfur, selenium, phosphorus and nitrogen donor ligands, investigated by electrospray mass spectrometry †
2000
Isothiocyanate‐rich Moringa oleifera extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice
2015
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Synthesis and biological activity of platinum(II) and palladium(II) thiosalicylate complexes with mixed ancillary donor ligands
2000
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Synergism from combinations of cisplatin and oxaliplatin with quercetin and thymoquinone in human ovarian tumour models.
2011
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Emerging DNA topoisomerase inhibitors as anticancer drugs
2004
Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis
1993
Consequences of Nucleic Acid Conformation on the Binding of a Trinuclear Platinum Drug
1999
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line.
2001
The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy
2007
Organometallic Anticancer Compounds
2010 Standout
Influence of the Spacer Length on the in Vitro Anticancer Activity of Dinuclear Ruthenium−Arene Compounds
2008
Interactions of anticancer Pt compounds with proteins: an overlooked topic in medicinal inorganic chemistry?
2012
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
2000 Standout
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Formation and Repair of Interstrand Cross-Links in DNA
2005
Highly tumorigenic lung cancer CD133 + cells display stem-like features and are spared by cisplatin treatment
2009
Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts.
1998
Profiling selected phytochemicals and nutrients in different tissues of the multipurpose tree Moringa oleifera L., grown in Ghana
2010
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Antitumour metal compounds: more than theme and variations
2007
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis
1993
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Transferring the Concept of Multinuclearity to Ruthenium Complexes for Improvement of Anticancer Activity
2009
Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview
2015 Standout
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
2003
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space
2016
In Vitro Anticancer Activity ofcis-Diammineplatinum(II) Complexes with β-Diketonate Leaving Group Ligands
2012
Antiangiogenic effects of the novel camptothecin ST1481 (gimatecan) in human tumor xenografts.
2003
A Non-Cross-Linking Platinum−Acridine Agent with Potent Activity in Non-Small-Cell Lung Cancer
2008
Works of C. Manzotti being referenced
A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts
1999
A Novel Trinuclear Platinum Complex Overcomes Cisplatin Resistance in an Osteosarcoma Cell System
1999
Importance of orthotopic implantation for human tumors as model systems: relevance to metastasis and invasion
1993
The novel trinuclear platinum complex BBR3464 induces a cellular response different from cisplatin
2001
Activity of a trinuclear platinum complex in human ovarian cancer cell lines sensitive and resistant to cisplatin: cytotoxicity and induction and gene-specific repair of DNA lesions
2001
Pharmacokinetics and Metabolism in Mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a New Oral C-seco-Taxane Derivative with Antiangiogenic Property Effective on Paclitaxel-Resistant Tumors
2006
The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo
2009
Sequence dependence of the antitumor and toxic effects of 5-fluorouracil and cis-diamminedichloroplatinum combination on primary colon tumors in mice
1988
Effects of a novel trinuclear platinum complex in cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines: interference with cell cycle progression and induction of apoptosis
2001
In vitro and in vivo antitumor activity of the novel trinuclear platinum complex BBR 3464 in neuroblastoma
2001
Development and validation of a LC–MS/MS method for the determination of the novel oral 1,14 substituted taxane derivatives, IDN 5738 and IDN 5839, in mouse plasma and its application to the pharmacokinetic study
2009
Comparison of cytotoxicity and cellular accumulation of polynuclear platinum complexes in L1210 murine leukemia cell lines
1999
Effects of 5-FU and cis-DDP Combination on Human Colorectal Tumor Xenografts
1989
BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin.
2000
cytotoxic Diamine-Platinum(II) Complexes with Methylsulfinyl Carboxylates as the Leaving Groups. Synthesis, Characterization,and Reactivity toward Chloride Ions, 5'-GMP, and 9-Methylguanine
1994
Bbr 2778, an Aza-anthracenedione Endowed with Preclinical Anticancer Activity and Lack of Delayed Cardiotoxicity
2001