Citation Impact
Citing Papers
Human high-altitude adaptation: forward genetics meets the HIF pathway
2014
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
SomaticHIF2AGain-of-Function Mutations in Paraganglioma with Polycythemia
2012
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
2010
Tumor Vasculature Is Regulated by PHD2-Mediated Angiogenesis and Bone Marrow-Derived Cell Recruitment
2009
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
A Knock-in Mouse Model of Human PHD2 Gene-associated Erythrocytosis Establishes a Haploinsufficiency Mechanism
2013
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
2015 StandoutNobel
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Ischemia and reperfusion—from mechanism to translation
2011 Standout
A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma
2012
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase
2009 StandoutNobel
HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression
2010
Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia
2016
Roles of individual prolyl‐4‐hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice
2012 StandoutNobel
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Paraneoplastic Syndromes Involving the Nervous System
2003 Standout
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
Cushing's syndrome
2015 Standout
Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia
2010
Hypoxia and Inflammation
2011 Standout
Antithrombotic Therapy for VTE Disease
2016 Standout
LIVER TRANSPLANTATION FOR METASTATIC NEUROENDOCRINE CARCINOMA
1998
Inflammatory myopathies: Clinical, diagnostic and therapeutic aspects
2003
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas
2011
Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia
2011
Clinical Features in Patients with Long-Lasting Macrophagic Myofasciitis
2014
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Primary prevention of deep venous thrombosis and pulmonary embolism in acute spinal cord injured patients
2002
Prevention of Venous Thromboembolism
2004 Standout
The immunology of stroke: from mechanisms to translation
2011 Standout
Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility
2010 StandoutNobel
The nonsystemic vasculitic neuropathies
2017
The Inferior Vena Cava Filter
2013
Functional Consequences of Succinate Dehydrogenase Mutations
2011
Hypoxic Adaptation in the Nervous System: Promise for Novel Therapeutics for Acute and Chronic Neurodegeneration
2016
New cancer targets emerging from studies of the Von Hippel‐Lindau tumor suppressor protein
2010 StandoutNobel
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
2013 StandoutNobel
Polyarteritis nodosa: A contemporary overview
2016
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Inclusion body myositis: current pathogenetic concepts and diagnostic and therapeutic approaches
2007
Genetics of abdominal aortic aneurysm
2013
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
Oxygen homeostasis
2009 StandoutNobel
Cellular senescence: from physiology to pathology
2014 Standout
Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection
2009
Therapeutic Manipulation of the HIF Hydroxylases
2009
New Syndrome of Paraganglioma and Somatostatinoma Associated With Polycythemia
2013
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
2017 Standout
Inflammatory Muscle Diseases
2015 Standout
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen
2014
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
The HIF Pathway and Erythrocytosis
2011
Pheochromocytoma: implications in tumorigenesis and the actual management.
2012
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
2018 StandoutNobel
Prolyl 4‐hydroxylases, master regulators of the hypoxia response
2013
Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets
2010
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
2015 StandoutNobel
Erythrocytosis: the HIF pathway in control
2013
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Rare Germline Mutations Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma
2014
Vitamin C is dispensable for oxygen sensing in vivo
2011
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Treatment of erythropoietin deficiency in mice with systemically administered siRNA
2012 StandoutNobel
Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline
2014 Standout
Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
2013
Works of C. Le Hello being referenced
Treatment of polyarteritis nodosa and microscopic polyangiitis without poor‐prognosis factors: A prospective randomized study of one hundred twenty‐four patients
2010
French Women From Multiplex Abdominal Aortic Aneurysm Families Should Be Screened
2005
Macrophagic myofasciitis associated with inclusion body myositis: a report of three cases
2001
PHD2 Mutation and Congenital Erythrocytosis with Paraganglioma
2008
[Prevalence of duplex ultrasonography detectable venous thrombosis in patients with suspected or acute pulmonary embolism].
2001
Orthotopic liver transplantation for metastases of bronchial carcinoid tumor
1993