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Citing Papers
Direct observation of thymine dimer repair in DNA by photolyase
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Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA
1995 StandoutNatureNobel
Triple Helix Formation with Short Oligonucleotide-Intercalator Conjugates Matching the HIV-1 U3 LTR End Sequence
1994
RNA-directed de novo methylation of genomic sequences in plants
1994
α-DNA VIII: thermodynamic parameters of complexes formed between the oligo-alpha-deoxynucleotides: α-d(GGAAGG) and α-d(CCTTCC) and their complementary oligo-beta-deoxynucleotides: β-d(CCTTCC) and β-d(GGAAGG) are different
1989
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
Directional antisense and sense cDNA cloning using Epstein-Barr virus episomal expression vectors
1989
Photochemical cross-linking of psoralen-derivatized oligonucleoside methylphosphonates to rabbit globin messenger RNA
1988
Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution
2000 StandoutNobel
Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo
2001
Sequence-specific recognition of the major groove of DNA by oligodeoxynucleotides via triple helix formation. Footprinting studies
1988
Crystal structure of parallel quadruplexes from human telomeric DNA
2002 StandoutNature
Pyrimidine phosphorothioate oligonucleotides form triplestranded helices and promote transcription inhibition
1994
Requirement for the replication protein SSB in human DMA excision repair
1991 Nature
Site-specific mutagenesis of T4 gene 32: the role of tyrosine residues in protein.cntdot.nucleic acid interactions
1989
Specific regulation of gene expression by antisense, sense and antigene nucleic acids
1990
Phosphodiesterases Involved in DNA Repair
1987
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Photomodification of RNA and DNA fragments by oligonucleotide reagents bearing arylazide groups
1993
α-DNA VI: comparative study of α- and β-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition
1987
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
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Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
RNA mimetics: oligoribonucleotide N3'-->P5' phosphoramidates
1998
Recognition of the four Watson–Crick base pairs in the DNA minor groove by synthetic ligands
1998 Nature
A role for the human single-Stranded DNA binding protein HSSB/RPA in an early stage of nucleotide excision repair
1992
Formation of a stable triplex from a single DNA strand
1990 Nature
New trends in photobiology
1993 StandoutNobel
The guanosine binding site of the Tetrahymena ribozyme
1989 StandoutNatureNobel
Sequence-targeted cleavage of nucleic acids by oligo-[.alpha.]thymidylate-phenanthroline conjugates: parallel and antiparallel double helices are formed with DNA and RNA, respectively
1988
Single-site enzymatic cleavage of yeast genomic DNA mediated by triple helix formation
1991 Nature
Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid
1990
Site-directed mutagenesis of the T4 endonuclease V gene: role of tyrosine-129 and -131 in pyrimidine dimer-specific binding
1988
Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA
1993
Preparation of a novel psoralen containing deoxyadenosine building block for the facile solid phase synthesis of psoralen-modified oligonucleotides for a sequence specific crosslink to a given target sequence
1989
The structure of the E. coli recA protein monomer and polymer
1992 StandoutNatureNobel
Evidence for a singlet intermediate in catalysis by Escherichia coli DNA photolyase and evaluation of substrate binding determinants
1988
Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?
1993 Science
Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome
1995 StandoutNobel
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities
2003
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Expanding the Catalytic Repertoire of Nucleic Acid Catalysts: Simultaneous Incorporation of Two Modified Deoxyribonucleoside Triphosphates Bearing Ammonium and Imidazolyl Functionalities
1999
Regulation of gene expression by small molecules
1997 Nature
Revealing the world of RNA interference
2004 StandoutNatureNobel
Inhibition of Simian Virus 40 DNA replication in CV-1 cells by an oligodeoxynucleotide covalently linked to an intercalating agent
1990
A phylogenomic study of DNA repair genes, proteins, and processes
1999
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Stabilization of Parallel Triplexes by Twisted Intercalating Nucleic Acids (TINAs) Incorporating 1,2,3‐Triazole Units and Prepared by Microwave‐Accelerated Click Chemistry
2007
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
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Oligonucleotide labeling methods 3. Direct labeling of oligonucleotides employing a novel, non-nucleosidic, 2-aminobutyl-1,3-propanediol backbone
1992
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Sequence-selective DNA recognition by synthetic ligands
1991
Synthesis of oligonucleotides containing a new azobenzene fragment with efficient photoisomerizability
1999
DNA‐Templated Organic Synthesis: Nature's Strategy for Controlling Chemical Reactivity Applied to Synthetic Molecules
2004 Standout
Telomerase: A target for cancer therapeutics
2002
Local Supercoil-Stabilized DNA Structure
1991
Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents
1991 Nature
Molecular mechanisms of action of antisense drugs
1999
cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates
1992 StandoutNobel
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1993 StandoutNobel
Splitting of Cis-syn Cyclobutane Thymine-thymine Dimers by Radiolysis and Its Relevance to Enzymatic Photoreactivation
1992 StandoutNobel
Interactions of bacteriophage T4-coded gene 32 protein with nucleic acids
1981
Photoregulation of DNA Triplex Formation by Azobenzene
2002
Deoxynucleic Guanidines/PNA (DNG/PNA) Chimeras: Oligonucleoside Analogue Containing Cationic Guanidinium and Neutral Amide Linkages
1999
A Specific Amino Acid Binding Site Composed of RNA
1988 Science
MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES
1986
Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity
1987
Deoxynucleic Guanidine/Peptide Nucleic Acid Chimeras: Synthesis, Binding and Invasion Studies with DNA
2000
DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions.
1993 StandoutNobel
Supramolecular Polymerization
2009 Standout
Complementary-Addressed (Sequence-Specific) Modification of Nucleic Acids
1985
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
2010
Binding of human single-stranded DNA binding protein to DNA damaged by the anticancer drug cis-diamminedichloroplatinum (II).
1992
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Investigation of complexes formed between gene 32 protein from bacteriophage T4 and heavy-atom-modified single-stranded polynucleotides using optical detection of magnetic resonance
1986
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
PHOTOSENSITIZED SPLITTING OF PYRIMIDINE DIMERS IN DNA BY INDOLE DERIVATIVES AND TRYPTOPHAN‐CONTAINING PEPTIDES
1975
Chiroptical Molecular Switches
2000 StandoutNobel
Cellular Uptake of Adamantyl Conjugated Peptide Nucleic Acids
1999
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Site-Specific Cleavage of a Yeast Chromosome by Oligonucleotide-Directed Triple-Helix Formation
1990 Science
A hybrid ribonuclease H. A novel RNA cleaving enzyme with sequence-specific recognition.
1992
The triple helix: 50 years later, the outcome
2008
Purification of nuclear proteins that bind to cisplatin-damaged DNA. Identity with high mobility group proteins 1 and 2.
1992
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.
1994 StandoutNobel
Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate.
1988 StandoutNobel
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA
1999
Synthesis and Thermodynamic and Biophysical Properties of Tricyclo-DNA
1999
Neutron scattering studies of lac repressor
1980 Nature
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide
1991 StandoutScience
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Targeted Mutagenesis in Mammalian Cells Mediated by Intracellular Triple Helix Formation
1995
Sequences of the ssb gene and protein.
1981 StandoutNobel
A Field Guide to Foldamers
2001 Standout
Crystal Structure of DNA Photolyase from Escherichia coli
1995 StandoutScienceNobel
Action mechanism of Escherichia coli DNA photolyase. III. Photolysis of the enzyme-substrate complex and the absolute action spectrum.
1987 StandoutNobel
Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity.
1987 StandoutNobel
Evidence that proteins S1, S11 1 and S21 directly participate in the binding of transfer RNA to the 30S ribosome
1978
Recombination Induced by Triple-Helix-Targeted DNA Damage in Mammalian Cells
1996
DNA-Templated Metal Catalysis
2003
Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality
2004 StandoutScienceNobel
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
1998 StandoutNobel
Assembly, subunit composition, and footprint of human DNA repair excision nuclease
1998 StandoutNobel
Antisense and Antigene Properties of Peptide Nucleic Acids
1992 Science
Site-Specific Cleavage of Human Chromosome 4 Mediated by Triple-Helix Formation
1991 Science
Recognition of Thymine Adenine Base Pairs by Guanine in a Pyrimidine Triple Helix Motif
1989 Science
Theoretical and Experimental Study of Isoguanine and Isocytosine: Base Pairing in an Expanded Genetic System
1997
The (A)BC excinuclease of Escherichia coli has only the UvrB and UvrC subunits in the incision complex.
1989 StandoutNobel
Proton NMR (500 MHz) of gene 32 protein-oligonucleotide complexes
1984
Fibers of RecA protein and complexes of RecA protein and single-stranded φX174 DNA as visualized by negative-stain electron microscopy
1986
Optimization of hybridizing abilities and nuclease resistance in the design of chimeric α-anomeric oligodeoxynucleotides containing β-anomeric gaps
1994
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
PHOTOREACTIVATING ENZYME FROM Streptomyces griseus—VI. ACTION SPECTRUM AND KINETICS OF PHOTOREACTIVATION
1986
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Association of Short-Strand DNA Oligomers with Guanidinium-Linked Nucleosides. A Kinetic and Thermodynamic Study
1996
Nucleosides and Oligonucleotides with Diynyl Side Chains: Base Pairing and Functionalization of 2′‐Deoxyuridine Derivatives by the Copper(I)‐Catalyzed AlkyneAzide ‘Click’ Cycloaddition
2007
Human DNA Repair Genes
2001 StandoutScienceNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Enzymatic amplification of translation inhibition of rabbit β-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents
1987
Second Structural Motif for Recognition of DNA by Oligonucleotide-Directed Triple-Helix Formation
1991 Science
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
2000 StandoutNobel
Inhibition of DNA Binding Proteins by Oligonucleotide-Directed Triple Helix Formation
1989 Science
REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism
1997
The contribution of DNA single-stranded order to the thermodynamics of duplex formation.
1991
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
1992 StandoutNobel
Works of C. Hélène being referenced
[New substances with high specific activity for nucleic acid sequences: oligodeoxynucleotides covalently linked to an intercalating agent].
1983
Kinetics and thermodynamics of triple-helix formation: effects of ionic strength and mismatched
1992
Circular dichroism studies of an oligo-α-thymidylate and of its interactions with complementary sequences
1988
Sequence-specific artificial photo-induced endonucleases based on triple helix-forming oligonucleotides
1990 Nature
Design of New Anti-Cancer Agents Based on Topoisomerase Poisons Targeted to Specific DNA Sequences
2001
A physico-chemical study of triple helix formation by an oligodeoxythymidylate with N3'->P5' phosphoramidate linkages
1997
Progress in Developments of Triplex-Based Strategies
1997
Effect of the terminal phosphate derivatization of β- and α-oligodeoxynucleotides on their antisense activity in protein biosynthesis, stability and uptake by eucaryotic cells
1992
The 1988 Walter Hubert lecture: Artificial control of gene expression by oligodeoxynucleotides covalently linked to intercalating agents
1989
Triple helix formation and the antigene strategy for sequence-specific control of gene expression
1999
Inhibition of Replication Initiation by Triple Helix-Forming Oligonucleotides
1995
An acridine-linked oligodeoxynucleotide targeted to the common 5' end of trypanosome mRNAs kills cultured parasites
1987
Oligothymidylates covalently linked to an acridine derivative and with modified phosphodiester backbone: circular dichroism studies of their Interactions with complementary sequences
1989
Antimessenger oligodeoxyribonucleotides: an alternative to antisense RNA for artificial regulation of gene expression — a review
1988
Triple helix-directed psoralen crosslinks are recognized by Uvr(A)BC excinuclease
1998
Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides
1989
Specific inhibition of mRNA translation by complementary oligonucleotides covalently linked to intercalating agents.
1986
Comparison of the E. ColiLac repressor and its tryptic core by hydrogen exchange studies. Effect of inducer binding
1979
Recognition of chemically damaged DNA by the gene 32 protein from bacteriophage T4.
1983
Stable triple helices formed by oligonucleotide N3'-->P5' phosphoramidates inhibit transcription elongation.
1996
Oligonucleotide clamps arrest DNA synthesis on a single-stranded DNA target.
1993
Binding of RecA protein to single-stranded nucleic acids: spectroscopic studies using fluorescent polynucleotides.
1983
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
2002
The role of tyrosine in the association of proteins and nucleic acids. Specific recognition of single-stranded nucleic acids by tyrosine-containing peptides.
1979
Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide.
1991
Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.
1989
Sequence-targeted Cleavage of single- and Double-stranded DNA by Oligothymidylates Covalently Linked to 1,10-Phenanthroline
1989
Oligothymidylates Substitubs en Position 3’ Par un Derive De L'Acridine
1986
Specific recognition of single-stranded nucleic acids. Interaction of tryptophan-containing peptides with native, denatured, and ultraviolet-irradiated DNA.
1977
Potential triple helix-mediated inhibition of IGF-I gene expression significantly reduces tumorigenicity of glioblastoma in an animal model.
1997
Photosensitized splitting of thymine dimers in DNA by gene 32 protein from phage T 4
1976
Sequence-targeted photochemical modifications of nucleic acids by complementary oligonucleotides covalently linked to porphyrins
1990
A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence.
1992
SPLITTING OF THYMINE DIMER BY HYDRATED ELECTRONS
1972
Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation.
1991
Specific inhibition of transcription by triple helix-forming oligonucleotides.
1992
Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate.
1989
Sequence-specific binding and photocrosslinking of alpha and beta oligodeoxynucleotides to the major groove of DNA via triple-helix formation.
1988
Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.
1993
Oligodeoxynucleotides covalently linked to intercalating dyes as base sequence-specific ligands. Influence of dye attachment site.
1984
Oligo(alpha-deoxynucleotide)s covalently linked to intercalating agents: differential binding to ribo- and deoxyribopolynucleotides and stability towards nuclease digestion.
1987
Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides
2000
Oligodeoxynucleotides covalently linked to intercalating agents: a new class of gene regulatory substances
1985
Triple-helix formation by oligonucleotides containing the three bases thymine, cytosine, and guanine.
1992
Stable triple helices are formed upon binding of RNA oligonucleotides and their 2'-O-methyl derivatives to double-helical DNA.
1992
Synthesis and structural studies of a self-complementary decadeoxynucleotide d(AATTGCAATT) I. - Synthesis and chemical characterization of the decanucleotide
1981
Nucleic acid-binding molecules with high affinity and base sequence specificity: intercalating agents covalently linked to oligodeoxynucleotides.
1984
Proton and phosphorus nuclear magnetic resonance studies of an oligothymidylate covalently linked to an acridine derivative and of its binding to complementary sequences
1985
Models of interaction between nucleic acids and proteins Hydrogen bonding of arginine with nucleic acid bases, phosphate groups and carboxylic acids
1979