Citation Impact
Citing Papers
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
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Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
2002 StandoutNobel
Extracellular domains drive homo- but not hetero-dimerization of erbB receptors
2000
Biochemical and Clinical Implications of the ErbB/HER Signaling Network of Growth Factor Receptors
1999
Bivalence of EGF-like ligands drives the ErbB signaling network
1997
Mechanism of activation of the TGF-β receptor
1994 StandoutNature
Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines
1989
Characterization of the oligosaccharide structures associated with the cystic fibrosis transmembrane conductance regulator
2000
Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg
1992 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
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Transmembrane TGF-α precursors activate EGF/TGF-α receptors
1989
Human Genetics Shape the Gut Microbiome
2014 Standout
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
1995 Standout
Microbial factors in inflammatory bowel disease
2002
Epidermal growth factor-related peptides and their receptors in human malignancies
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Unravelling the pathogenesis of inflammatory bowel disease
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Cell Signaling by Receptor Tyrosine Kinases
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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
2003
Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation
1994
A genetic model for colorectal tumorigenesis
1990 Standout
Signal transduction by receptors with tyrosine kinase activity
1990 Standout
Two EGF molecules contribute additively to stabilization of the EGFR dimer
1997
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Regulation of signal transduction and signal diversity by receptor oligomerization
1994
Phosphatidylinositol-3-OH kinase direct target of Ras
1994 StandoutNature
Gβγ Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor
1995 StandoutNobel
EGF Activates Its Receptor by Removing Interactions that Autoinhibit Ectodomain Dimerization
2003
Erlotinib in Previously Treated Non–Small-Cell Lung Cancer
2005 Standout
Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission
2013
The p53 tumour suppressor gene
1991 StandoutNature
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Increased expression of mutant forms of p53 oncogene in primary lung cancer
1990
A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)
1992
Inflammatory Bowel Disease
1991
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Protein modules and signalling networks
1995 StandoutNature
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
Oncogenes and signal transduction
1991 Standout
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
1994 StandoutNature
Epidermal growth factor receptors: critical mediators of multiple receptor pathways
1999
Head and Neck Cancer
1993 Standout
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
Cystic fibrosis: molecular biology and therapeutic implications
1992 StandoutScience
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance
1991
Diversity, stability and resilience of the human gut microbiota
2012 StandoutNature
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
Integrins
2002 Standout
Growth factor signaling by receptor tyrosine kinases
1992
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck
1989
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Novel composite core-shell nanoparticles as busulfan carriers
2006
Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile
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Changes in the Composition of the Human Fecal Microbiome After Bacteriotherapy for Recurrent Clostridium difficile-associated Diarrhea
2010
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins
1991 StandoutScience
p53 Mutations in Human Cancers
1991 StandoutScience
The secreted form of the epidermal growth factor receptor. Characterization and crystallization of the receptor-ligand complex.
1990
Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation.
1995
Long range propagation of conformational changes in integrin alpha IIb beta 3.
1993
SH2 domains recognize specific phosphopeptide sequences
1993 Standout
The Interaction between the Drosophila Secreted Protein Argos and the Epidermal Growth Factor Receptor Inhibits Dimerization of the Receptor and Binding of Secreted Spitz to the Receptor
2000
Epidermal Growth Factor Receptor in Non–Small-Cell Lung Carcinomas: Correlation Between Gene Copy Number and Protein Expression and Impact on Prognosis
2003
Structure of the Extracellular Region of HER3 Reveals an Interdomain Tether
2002 Science
Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms
1990 StandoutScience
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
Stable expression of truncated inositol 1,4,5-trisphosphate receptor subunits in 3T3 fibroblasts. Coordinate signaling changes and differential suppression of cell growth and transformation.
1994 StandoutNobel
Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85β protein by using the baculovirus expression system
1992
Molecular correlates of gefitinib responsiveness in human bladder cancer cells
2007
Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex
1992 StandoutScience
The SV40 TC-II(kappa B) and the related H-2Kb enhansons exhibit different cell type specific and inducible proto-enhancer activities, but the SV40 core sequence and the AP-2 binding site have no enhanson properties.
1989
Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants.
1992
Growth Factors and Cancer
1991 StandoutScience
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Metal–Organic Frameworks in Biomedicine
2011 Standout
Fusion of a Kinase Gene, ALK , to a Nucleolar Protein Gene, NPM , in Non-Hodgkin's Lymphoma
1994 StandoutScience
Geometric Control of Cell Life and Death
1997 StandoutScience
Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
1994 StandoutNatureNobel
Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells.
1992
Structural organization of the human insulin receptor ectodomain
1992
EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
2004 Standout
Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53
1990 StandoutScience
Works of C. Greenfield being referenced
Clostridium difficile and inflammatory bowel disease.
1983
Epidermal growth factor receptors in lung tumours
1987
Expression of the human EGF receptor with ligand-stimulatable kinase activity in insect cells using a baculovirus vector.
1988
Epidermal growth factor binding induces a conformational change in the external domain of its receptor.
1989
[52] Expression and properties of epidermal growth factor receptor expressed from baculovirus vectors
1991
Evaluation of epidermal growth factor receptors in bladder tumours
1987
DIMETHYLSULPHOXIDE-INDUCED TOXICITY
1980