Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Concurrent Cisplatin-Based Radiotherapy and Chemotherapy for Locally Advanced Cervical Cancer
1999 Standout
Applicability of animal tumor data to cancer therapy in humans
1988
Targeting hypoxia in cancer therapy
2011 Standout
The role of porphyrin chemistry in tumor imaging and photodynamic therapy
2010 Standout
Chemical Radiosensitizers for Use in Radiotherapy
2007
Free Radicals as Mediators of Tissue Injury and Disease
1993 Standout
Physiological concentrations of purines and pyrimidines
1994 Standout
Drug penetration in solid tumours
2006 Standout
Synthetic, structural and kinetic studies on the binding of cyclohexane-1,2-bis(4-methyl-3-thiosemicarbazone) to divalent metal ions (Co, Ni, Cu, Zn or Cd)
2008 StandoutNobel
Radiosensitization by 2-nitroimidazole nucleoside analog rp-170: Radiosensitizing effects under both intravenous and oral administration
1992 StandoutNobel
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Radiosensitization by a new potent nucleoside analog: 1-(1′,3′,4′-trihydroxy-2′-butoxy)methyl-2-nitroimidazole(RP-343)
1993 StandoutNobel
Exploiting tumour hypoxia in cancer treatment
2004 Standout
Radiosensitization by a new nucleoside analogue: 1-[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl-2-nitroimidazole (RP-170)
1989 StandoutNobel
The metabolic activation of nitroheterocyclic therapeutic agents
1988
Tirapazamine causes vascular dysfunction in HCT-116 tumour xenografts
2006
Chemotherapy and the war on cancer
2005 Standout
Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm
1993 StandoutNobel
Targeting gene expression to hypoxic tumor cells
1997 StandoutNobel
Radiation chemistry comes before radiation biology
2009
Investigation into 64Cu-labeled Bis(selenosemicarbazone) and Bis(thiosemicarbazone) complexes as hypoxia imaging agents
2005
The deoxyribose method: A simple “test-tube” assay for determination of rate constants for reactions of hydroxyl radicals
1987 Standout
A phase I/II study of the hypoxic cell sensitizer misonidazole as an adjunct to high fractional dose radiotherapy in patients with unresectable squamous cell carcinoma of the head and neck: A RTOG randomized study (#79-04)
1989
Real-Time Assessment of Tissue Hypoxia In Vivo with Combined Photoacoustics and High-Frequency Ultrasound
2014
Clinical Pharmacology of 5-Fluorouracil
1989 Standout
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
Stress-induced recrystallization of a protein crystal by electron irradiation
1999 StandoutNatureNobel
Head and Neck Cancer
2001 Standout
Evaluation of Various Types of New Hypoxic Cell Sensitizers Using the EMT6 Single Cell—Spheroid—Solid Tumour System
1987
Hypoxic cell radiosensitizers as potential adjuvants to conventional chemotherapy for the treatment of cancer
1982
Electron spin resonance studies of radiation damage to DNA and to proteins
1995
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.
1994 Standout
Partition Coefficient as a Guide to the Development of Radiosensitizers Which Are Less Toxic Than Misonidazole
1980
Bonding and structure trends of thiosemicarbazone derivatives of metals—An overview
2008 Standout
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
HYPOXIC CELL SENSITISERS IN RADIOTHERAPY
1976
Radiosensitizers of hypoxic cells in solid tumours
1976
Radiosensitization of Hypoxic HeLa S3 Cellsin Vitroby a New Type of Radiosensitizer: Spermine and Spermidine Amides with Nitro Groups
1983
Hypoxia-specific cytotoxins in cancer therapy
1996
The Role of Oxidative Stress in Neurodegenerative Diseases
2015 Standout
Metal Complexes as Photo- and Radiosensitizers
1999
Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells
1985
Pathways to Functionalized Heterocycles: Propargyl Rearrangement using B(C6F5)3
2015
A REVIEW OF INTERACTIONS BETWEEN PLATINUM COORDINATION COMPLEXES AND IONIZING RADIATION: IMPLICATIONS FOR CANCER THERAPY
1980
Radiosensitizing and Cytotoxicity Studies with CB 1954 (2,4-Dinitro-5-Aziridinylbenzamide)
1981
In vitro and in vivo radiosensitization by 2-nitroimidazoles more electron-affinic than misonidazole
1982
Reactions of some nitrogen heterocycles with chlorodifluoromethane under conditions of phase-transfer catalysis
2005
Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement
2020 StandoutNobel
Clinical trials of radiosensitizers: What should we expect?
1984
Structure-pharmacokinetic relationships for misonidazole analogues in mice
1981
Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model
1988 StandoutScience
Effects of misonidazole on purine metabolism in ehrlich ascites tumor cells in vitro
1980
Studies on the effects of the antitumor agent camptothecin and derivatives on DNA. Camptothecin potentiated cleavage of DNA by bleomycin in vitro
1981
Reductive activation of nitroimidazoles in anaerobic microorganisms
1986
Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential.
1997
The National Cancer Chemotherapy Program
1982 Science
The broadening reach of frustrated Lewis pair chemistry
2016 StandoutScience
Radiation sensitization and chemopotentiation: Rsu 1069, a compound more efficient than misonidazole in vitro and in vivo
1984
The multicellular spheroid system as a tumor model for studies of radiation sensitizers
1980
Mechanisms of hypoxic cell radiosensitization and the development of new sensitizers
1982
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Misonidazole and MTDQ in combination: Cytotoxic and radiosensitizing properties in hypoxic mammalian cells
1979
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture.
1999
Clinical and Microbiological Aspects ofTrichomonas vaginalis
1998 Standout
Application of pulse radiolysis methods to study the reactions and structure of biomolecules
1978
Substituted 2,5-diazabicyclo[4.1.0]heptanes and their application as general piperazine surrogates: synthesis and biological activity of a Ciprofloxacin analogue
2010
The Pharmacokinetics and Tumor and Neural Tissue Penetrating Properties of SR-2508 and SR-2555 in the Dog-Hydrophilic Radiosensitizers Potentially Less Toxic than Misonidazole
1980
International Staging System for Multiple Myeloma
2005 Standout
Works of C. E. Smithen being referenced
Romazarit. A potential disease-modifying antirheumatic drug
1991
Radiosensitization of Hypoxic Cells in vitro: a Water-soluble Derivative of Paranitroacetophenone
1972
Electron-Affinic Sensitization: VII. A Correlation between Structures, One-Electron Reduction Potentials, and Efficiencies of Nitroimidazoles as Hypoxic Cell Radiosensitizers
1976
Structure-activity Relationships in the Development of Hypoxic Cell Radiosensitizers
1979
Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results
1975
181. The mechanism of heterocyclic ring expansions. Part I. The reaction of 2,3-dimethylindole with dichlorocarbene
1964
Comparative studies of hypoxic-cell radiosensitization using artificially hypoxic skin in vivo
1982
Electron Affinic Sensitization: V. Radiosensitization of Hypoxic Bacteria and Mammalian Cells in Vitro by Some Nitroimidazoles and Nitropyrazoles
1974
Polyfunctional Radiosensitizers: VII. Radiosensitization by Conformationally-Restricted Isomers of a Nitroxyl Biradical in Vitro
1985
Polyfunctional radiosensitizers IV. The effect of contact time and temperature on sensitization of hypoxic Chinese hamster cells in vitro by bifunctional nitroxyl compounds.
1978
182. The mechanism of heterocyclic ring expansions. Part II. The reaction of methylindoles with halogenocarbenes
1964
Structure-activity Relationships in the Development of Hypoxic Cell Radiosensitizers
1979
Polyfunctional Radiosensitizers: I. Effects of a Nitroxyl Biradical on the Survival of Mammalian Cells in Vitro
1976
Electron-Affinic SensitizationVII. A Correlation between Structures, One-Electron Reduction Potentials, and Efficiencies of Nitroimidazoles as Hypoxic Cell Radiosensitizers
2012