Standout Papers
Citation Impact
Citing Papers
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
1994 Nature
Reshaping human antibodies for therapy
1988 StandoutNatureNobel
Circular DNA is excised by immunoglobulin class switch recombination
1990 StandoutNobel
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
The Primary Immunodeficiencies
1995
Localization of the binding site for the human high-affinity Fc receptor on IgG
1988 StandoutNatureNobel
The binding site for C1q on IgG
1988 StandoutNatureNobel
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
Hybrid hybridomas and their use in immunohistochemistry
1983 StandoutNatureNobel
Structural patterns in globular proteins
1976 StandoutNatureNobel
Structure of human immunoglobulin gamma genes: implications for evolution of a gene family
1982 StandoutNobel
Cloning of immunoglobulin kappa light chain genes from mouse liver and myeloma MOPC 173
1979
The Predicted Structure of Immunoglobulin D1.3 and Its Comparison with the Crystal Structure
1986 StandoutScienceNobel
Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination.
1979 StandoutNobel
Structural alterations in J regions of mouse immunoglobulin λ genes are associated with differential gene expression
1982 Nature
Structural Basis for Antigen-Antibody Recognition
1986 StandoutScienceNobel
Complete nucleotide sequence of immunoglobulin γ2b chain gene cloned from newborn mouse DNA
1980 StandoutNatureNobel
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene
1983 StandoutNobel
Fusion of Two Immunoglobulin-producing Myeloma Cells
1973 StandoutNatureNobel
Evidence for an ancestral immunoglobulin gene coding for half a domain
1975
The complete nucleotide sequence of mouse immunoglobulin γ2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer
1981 StandoutNobel
Variation and Homology in the Mu and Gamma Heavy Chains of Human Immunoglobulins
1971 Science
Variable region sequence of the heavy chain from a phosphorylcholine binding myeloma protein
1974
Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangments in heavy chain V-region gene segments
1980 Nature
An IgG2a-producing variant of an IgG2b-producing mouse myeloma cell line. Structural studies on the Fc region of parent and variant heavy chains
1978
Japanese wild mouse, Mus musculus molossinus, has duplicated immunoglobulin γ2a genes
1982 StandoutNatureNobel
Biosynthesis of immunoglobulins
1972
Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain gene
1979 StandoutNobel
The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes
1981 StandoutNobel
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification
1983 StandoutNatureNobel
Analysis of the repertoire of anti‐(4‐hydroxy‐3‐nitro‐phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti‐idiotope antibodies
1979
Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions.
1983 StandoutNobel
Evolution of immunoglobulin subclasses. Primary structure of a murine myeloma gamma1 chain.
1978
Rat × rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG
1979 StandoutNatureNobel
Somatic mutation of immunoglobulin light-chain variable-region genes
1981
Multiple differences between the nucleic acid sequences of the IgG2aa and IgG2ab alleles of the mouse.
1981 Nobel
Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes
1981 StandoutNatureNobel
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes
1980 StandoutNatureNobel
Amino-Acid Sequence of the Variable Region of the Heavy (Alpha) Chain of a Mouse Myeloma Protein with Anti-Hapten Activity
1974
Expression of lymphocyte surface IgE does not require switch recombination
1982 StandoutNatureNobel
Frequency of expressed immunoglobulin light chain genes in lipopolysaccharide-stimulated BALB/c spleen cells.
1984 StandoutNobel
Chemical Characterization of a Mouse Immunoglobin A Heavy Chain with a 100-Residue Deletion
1974
A mendelian idiotype is demonstrable in the heteroclitic anti‐NP antibodies of the mouse
1978
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.
1980 StandoutNobel
Antigen-Binding Myeloma Proteins of Mice
1978
Cloning of mouse immunoglobulin epsilon gene and its location within the heavy chain gene cluster.
1981
Nucleotide sequences of class-switch recombination region of the mouse immunoglobulin λ2b-chain gene
1980 StandoutNobel
Unusual organization and diversity of T-cell receptor a-chain genes
1985 StandoutNatureNobel
Ordering of mouse immunoglobulin heavy chain genes by molecular cloning
1981 StandoutNatureNobel
Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter
1986 StandoutNatureNobel
Isotypes of IgG: Comparison of the primary structures of three pairs of isotypes which differ in their ability to activate complement
1979
Three-Dimensional Structure of the Fab′ Fragment of a Human Immunoglobulin at 2.8-Å Resolution
1973
Initiation of Protein Synthesis at an Unusual Position in an Immunoglobulin Gene?
1972 StandoutScienceNobel
Organization of the constant-region gene family of the mouse immunoglobulin heavy chain
1982 StandoutNobel
Deletion of immunoglobulin heavy chain genes from expressed allelic chromosome
1980 StandoutNatureNobel
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone
1984 StandoutNatureNobel
Sequences and Factors: A Guide to MHC Class-II Transcription
1992
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
Molecular analysis of spontaneous somatic mutants
1977 StandoutNatureNobel
Restricted reassociation of heavy and light chains from hapten-specific monoclonal antibodies.
1981
Mouse Immunoglobulin Subclasses: Cyanogen Bromide Fragments and Partial Sequence of a gamma1 Chain
1975 StandoutNobel
Replacing the complementarity-determining regions in a human antibody with those from a mouse
1986 StandoutNatureNobel
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments
1979 StandoutNatureNobel
Immunoglobulin Gene Rearrangement in Immature B Cells
1980 StandoutScienceNobel
Determination of the Primary Structure of a Mouse IgG2a Immunoglobulin: Amino‐Acid Sequence of the Fc Fragment
1974
The disulphide bridges of a mouse immunoglobulin G1 protein
1972 StandoutNobel
A functional γ gene formed from known γ-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes
1986 StandoutNatureNobel
Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes
1981 StandoutNatureNobel
IgG2a-producing variants of an IgG2b-producing mouse myeloma cell line.
1978
The Primary Immunodeficiencies
1984
Sequence analysis of immunoglobulin light chain messenger RNA
1974 StandoutNatureNobel
Determination of the Primary Structure of a Mouse IgG2a Immunoglobulin
1975
Mouse Immunoglobulin Heavy Chains Are Coded by Multiple Germ Line Variable Region Genes
1974
Somatic generation of antibody diversity
1983 StandoutNatureNobel
An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing
1980 StandoutNatureNobel
Lambda Chains and Genes in Inbred Mice
1985
Structure of the constant and 3′ untranslated regions of the murine Balb/c γ2a heavy chain messenger RNA
1980
Sequences at the somatic recombination sites of immunoglobulin light-chain genes
1979 StandoutNatureNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Genetics of IgCH (allotype) locus in the mouse
1978
Switch region of immunoglobulin Cμ gene is composed of simple tandem repetitive sequences
1981 StandoutNatureNobel
Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer.
1980 StandoutNobel
Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution.
1978
Works of C. de Préval being referenced
Position 71 in the α helix of the DRβ domain is predicted to influence peptide binding and plays a central role in allorecognition
1993
Regulation of Genes for HLA Class II Antigens in Cell Lines from Patients with Severe Combined Immunodeficiency
1988
Variability of Interchain Binding of Immunoglobulins: Interchain Bridges of Mouse IgG2a and IgG2b
1970 StandoutNatureNobel
Sequence of Amino Acids of the NH2‐Terminal Region of a Mouse‐Clonal Immunoglobulin Heavy Chain
1972
The complete sequence of the murine monoclonal immunoglobulin MOPC 173 (IgG2a): genetic implications.
1977
Specific interaction between VH and VL regions of human monoclonal immunoglobulins
1976
Determination of the Primary Structure of a Mouse γG2a Immunoglobulin Identification of the Disulfide Bridges
1972
A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes
1985 Nature
On the Genetic Dissection of a Specific Humoral Immune Response to (1,3) Dextran
1977
A defect in the regulation of major histocompatibility complex class II gene expression in human HLA-DR negative lymphocytes from patients with combined immunodeficiency syndrome.
1985