Citation Impact
Citing Papers
Gene Therapy and Infection Control: More Light on the Way
2000
MYC Drives Pten/Trp53 -Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2
2015
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
A Novel Small Molecule Inhibitor of Signal Transducers and Activators of Transcription 3 Reverses Immune Tolerance in Malignant Glioma Patients
2007
Phase II Study of Cediranib, an Oral Pan–Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent Glioblastoma
2010
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Stem Cell–like Glioma Cells Promote Tumor Angiogenesis through Vascular Endothelial Growth Factor
2006
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant Phenolic Acids
2023 StandoutNobel
Antibiotic Management of Lung Infections in Cystic Fibrosis. I. The Microbiome, Methicillin-Resistant Staphylococcus aureus , Gram-Negative Bacteria, and Multiple Infections
2014
Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses
2008
Sputum Biomarkers of Inflammation in Cystic Fibrosis Lung Disease
2007
EGFR Antagonists in Cancer Treatment
2008 Standout
Engineering adeno-associated viruses for clinical gene therapy
2014
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Circular Intermediates of Recombinant Adeno-Associated Virus Have Defined Structural Characteristics Responsible for Long-Term Episomal Persistence in Muscle Tissue
1998
Cell Lines for the Production of Recombinant Adeno-Associated Virus
1995
Development and Optimization of a Real-Time Quantitative PCR-Based Method for the Titration of AAV-2 Vector Stocks
2002
Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508delCFTR
2015 Standout
Cholecystokinin is a physiological hormonal mediator of fat‐induced inhibition of gastric emptying in man
1988
The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; A review
2006
Cystic fibrosis
2016 Standout
Cytomegalovirus Infection After Intestinal/Multivisceral Transplantation
2015
Updated International Consensus Guidelines on the Management of Cytomegalovirus in Solid-Organ Transplantation
2013
DNA-polycation nanospheres as non-viral gene delivery vehicles
1998
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
1994
Dynamics of cell‐mediated immune responses to cytomegalovirus in pediatric transplantation recipients
2011
A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
2016 Standout
Principles of nanoparticle design for overcoming biological barriers to drug delivery
2015 Standout
Efficacy of Extended Valganciclovir Prophylaxis in Preventing Cytomegalovirus Infection in Pediatric Kidney Transplantation
2014
Glioblastoma and Other Malignant Gliomas
2013 Standout
Cystic Fibrosis Pulmonary Guidelines
2007
Lung clearance index: Evidence for use in clinical trials in cystic fibrosis
2013
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
The use of cyclooxygenase-2 inhibitors for improvement of efficacy of radiotherapy in cancers
2016
Stimuli-responsive nanocarriers for drug delivery
2013 Standout
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection
2006 StandoutNobel
Inhibition of angiogenesis and invasion in malignant gliomas
2007
Molecularly targeted therapy for malignant glioma
2007
Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
2014 Standout
Pharmacotherapy of impaired mucociliary clearance in non‐CF pediatric lung disease. A review of the literature
2007
A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation
2011 Standout
Modern Flow Cytometry: A Practical Approach
2007
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
2006 Standout
Salmonella typhi uses CFTR to enter intestinal epithelial cells
1998 StandoutNatureNobel
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Distinct Neuronal Coding Schemes in Memory Revealed by Selective Erasure of Fast Synchronous Synaptic Transmission
2012 StandoutNobel
Precise hit: adeno-associated virus in gene targeting
2005
Scalable Downstream Strategies for Purification of Recombinant Adeno- Associated Virus Vectors in Light of the Properties
2015
Malignant Gliomas in Adults
2008 Standout
Adeno-associated virus and the development of adeno-associated virus vectors: a historical perspective
2004
Enhanced Expression of Transgenes from Adeno-Associated Virus Vectors with the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element: Implications for Gene Therapy
1999
VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer
2009
Inhibiting kinases in malignant gliomas
2007
Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer
2015 Standout
Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
2011
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Loss of CFTR Chloride Channels Alters Salt Absorption by Cystic Fibrosis Airway Epithelia In Vitro
1998
Magnetic Nanoparticles Enhance Adenovirus Transduction In Vitro and In Vivo
2011
The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation
2018 Standout
Interferon-α2b Secretion by Adenovirus-Mediated Gene Delivery in Rat, Rabbit, and Chimpanzee Results in Similar Pharmacokinetic Profiles
2002
A directed evolution approach to select for novel Adeno-associated virus capsids on an HIV-1 producer T cell line
2017
Natural and synthetic STAT3 inhibitors reduce hepcidin expression in differentiated mouse hepatocytes expressing the active phosphorylated STAT3 form
2010
Assessment of Cytomegalovirus Hybrid Preventative Strategy in Pediatric Heart Transplant Patients
2012
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
1999 Standout
The gastrointestinal mucus system in health and disease
2013
Airway Mucus Function and Dysfunction
2010 Standout
Cystic fibrosis microbiology: Advances in antimicrobial therapy
2015
Manufacturing of recombinant adeno-associated viral vectors for clinical trials
2016
Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System
2004
Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments
2009 Standout
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Inflammation in cystic fibrosis lung disease: Pathogenesis and therapy
2015
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Development of Novel Cell Surface CD34-Targeted Recombinant Adenoassociated Virus Vectors for Gene Therapy
1998
Herpes Zoster
2013 Standout
Probing the Functional Equivalence of Otoferlin and Synaptotagmin 1 in Exocytosis
2011 StandoutNobel
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
A consensus document for the selection of lung transplant candidates: 2014—An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation
2014 Standout
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography
2006
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics
2001
Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8.
1995
Angiogenesis as a therapeutic target
2005 StandoutNature
Tumor Angiogenesis
2008 Standout
Diagnosis and Treatment of High-Grade Astrocytoma
2007
Anemia of Chronic Disease
2005 Standout
Antibiotic and Anti-Inflammatory Therapies for Cystic Fibrosis
2013
Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization
2000
Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
2009
Treatment of lung infection in patients with cystic fibrosis: Current and future strategies
2012
Sputum Biomarkers of Inflammation and Lung Function Decline in Children with Cystic Fibrosis
2012
Early Respiratory Infection Is Associated with Reduced Spirometry in Children with Cystic Fibrosis
2014
Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis
2003 Standout
Compacted DNA Nanoparticles Administered to the Nasal Mucosa of Cystic Fibrosis Subjects Are Safe and Demonstrate Partial to Complete Cystic Fibrosis Transmembrane Regulator Reconstitution
2004
Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial
2017
Adeno-Associated Virus at 50: A Golden Anniversary of Discovery, Research, and Gene Therapy Success—A Personal Perspective
2015
Quantitative Analysis of the Packaging Capacity of Recombinant Adeno-Associated Virus
1996
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
The Incidence, Correlation with Tumor-Infiltrating Inflammation, and Prognosis of Phosphorylated STAT3 Expression in Human Gliomas
2008
Optogenetic Dissection of Entorhinal-Hippocampal Functional Connectivity
2013 StandoutScienceNobel
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
Immunomodulation in Cystic Fibrosis: Why and How?
2020
Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine
2006 StandoutNobel
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Therapeutic Application of Noncytotoxic Molecular Targeted Therapy in Gliomas: Growth Factor Receptors and Angiogenesis Inhibitors
2008
Angiogenesis as a Therapeutic Target in Malignant Gliomas
2009
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
2009 Standout
Nonviral Vectors for Gene Delivery
2008 Standout
Bacterial Biofilms: A Common Cause of Persistent Infections
1999 StandoutScience
Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein
1996
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients.
1996
Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma
2007
Characterization of Adeno-Associated Virus Genomes Isolated from Human Tissues
2005
Adenoviral and AAV-Mediated Gene Transfer to the Inner Ear: Role of Serotype, Promoter, and Viral Load on In Vivo and In Vitro Infection Efficiencies
2009
In Vivo Potency Assay for Adeno-Associated Virus–Based Gene Therapy Vectors Using AAVrh.10 as an Example
2018
2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings
2007 Standout
Combination of Antiangiogenic Therapy With Other Anticancer Therapies: Results, Challenges, and Open Questions
2005
In vitro gene expression on smooth muscle cells using a terplex delivery system
1997
EM574, an erythromycin derivative, improves delayed gastric emptying of semi-solid meals in conscious dogs
2000 StandoutNobel
Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin
1997
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
2003 StandoutNobel
2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host
2013 Standout
Viral Vectors for Gene Therapy
1998
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector
1996
Lessons learned in the development of targeted therapy for malignant gliomas
2007
Adeno-associated viruses undergo substantial evolution in primates during natural infections
2003
Idiopathic Pulmonary Fibrosis
2018 Standout
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor
2001 StandoutNobel
Works of C. Conrad being referenced
High-dose oral N -acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis
2006
The Risk, Prevention, and Outcome of Cytomegalovirus After Pediatric Lung Transplantation
2009
Variability in immunization guidelines in children before and after lung transplantation
2007
A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo
2006
Gene Therapy Vectors As Drug Delivery Systems
1995
Increased Mortality After Pulmonary Fungal Infection Within the First Year After Pediatric Lung Transplantation
2008
Clinical Infection Control in Gene Therapy: A Multidisciplinary Conference
2000
Multicenter Evaluation of Infant Lung Function Tests as Cystic Fibrosis Clinical Trial Endpoints
2010
American Society of Transplantation Executive Summary on Pediatric Lung Transplantation
2006
A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma
2010
Cytomegalovirus Immunoglobulin Decreases the Risk of Cytomegalovirus Infection but not Disease After Pediatric Lung Transplantation
2009
Long-term treatment with oral N-acetylcysteine: Affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial
2014
Novel tobramycin inhalation powder in cystic fibrosis subjects: Pharmacokinetics and safety
2007
Safety and Biological Efficacy of an Adeno‐Associated Virus Vector–Cystic Fibrosis Transmembrane Regulator (AAV‐CFTR) in the Cystic Fibrosis Maxillary Sinus
1999
Resistin is elevated in cystic fibrosis sputum and correlates negatively with lung function
2018
Respiratory viral infections within one year after pediatric lung transplant
2009
Phase I Trial of Intranasal and Endobronchial Administration of a Recombinant Adeno-Associated Virus Serotype 2 (rAAV2)-CFTR Vector in Adult Cystic Fibrosis Patients: A Two-Part Clinical Study
2003
A Phase II, Double-Blind, Randomized, Placebo-Controlled Clinical Trial of tgAAVCF Using Maxillary Sinus Delivery in Patients with Cystic Fibrosis with Antrostomies
2002
A Phase I Study of an Adeno-Associated Virus-CFTR Gene Vector in Adult CF Patients with Mild Lung Disease. Johns Hopkins Children's Center, Baltimore, Maryland
1996
A phase I/II trial of single-agent PTK 787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in patients with recurrent glioblastoma multiforme (GBM)
2004
Risk Factors for Small Bowel Bacterial Overgrowth in Cystic Fibrosis
2007
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.
1993
A phase I/II trial of PTK787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM)
2004
A phase I/II trial of single-agent PTK 787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in patients with recurrent glioblastoma multiforme (GBM)
2004
A phase I study of AEE788, a novel multitargeted inhibitor of ErbB and VEGF receptor family tyrosine kinases, in recurrent GBM patients
2005
In vivo model of adeno-associated virus vector persistence and rescue
1996
Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways
2008
A phase I study of temozolomide (TMZ) and the farnesyltransferase inhibitor (FTI), lonafarnib (Sarazar, SCH66336) in recurrent glioblastoma
2006
Metabolic Adaptation of Neutrophils in Cystic Fibrosis Airways Involves Distinct Shifts in Nutrient Transporter Expression
2013
Regulation of gastric emptying in humans by cholecystokinin.
1986
Phase II study of combination carboplatin and erlotinib in patients with recurrent glioblastoma multiforme
2007
Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs
2009
Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung.
1996
A phase I/II trial of PTK787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM)
2004