Citation Impact
Citing Papers
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
2006
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Non-motor symptoms of Parkinson's disease: diagnosis and management
2006 Standout
Metabolic side effects of antipsychotic drug treatment – pharmacological mechanisms
2009
NeuPSIG guidelines on neuropathic pain assessment
2010 Standout
Atypical Neuroleptics Have Low Affinity for Dopamine D2 Receptors or Are Selective for D4 Receptors
1997
Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia
2005 Standout
Neural mechanism underlying acupuncture analgesia
2008 Standout
Molecular, pharmacological and functional diversity of 5-HT receptors
2002 Standout
Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs
2004
Descending control of pain
2002 Standout
Behavioral Evidence for Interactions between a Hallucinogenic Drug and Group II Metabotropic Glutamate Receptors
2000
Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia
2005
Receptor subtype and dose dependence of dexmedetomidine-induced accumulation of [14C]glutamine in astrocytes suggests glial involvement in its hypnotic-sedative and anesthetic-sparing effects
2000
Agonist efficacy and receptor efficiency in heterozygous CB1 knockout mice: relationship of reduced CB1 receptor density to G‐protein activation
2001
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Network pharmacology: the next paradigm in drug discovery
2008 Standout
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Impulsivity, Compulsivity, and Top-Down Cognitive Control
2011 Standout
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels
2009 StandoutNobel
The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine?s actions?
2004
Psychedelics
2016 Standout
REVIEW ON CPP: Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade
2007 Standout
Triptans in Migraine
2000
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
2011 Standout
Agonist-independent Activation of Gz by the 5-Hydroxytryptamine1A Receptor Co-expressed in Spodoptera frugiperda Cells
1997
The Role of Serotonin in Antipsychotic Drug Action
1999
Identification of serotonin 5-HT1A receptor partial agonists in ginger
2010
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats
2000
GPCR–Gα fusion proteins: molecular analysis of receptor–G-protein coupling
1999 StandoutNobel
The dopamine D4 receptor: biochemical and signalling properties
2010
Relationship Between Dopamine D2 Occupancy, Clinical Response, and Side Effects: A Double-Blind PET Study of First-Episode Schizophrenia
2000 Standout
Expression of Serotonin1A and Serotonin2A Receptors in Pyramidal and GABAergic Neurons of the Rat Prefrontal Cortex
2004
Interplay between Cortical Spreading Depolarization and Seizures
2017 Standout
Major Depressive Disorder
2008 Standout
The neural basis of psychedelic action
2022 Standout
Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI
2008
Activation of pyramidal cells in rat medial prefrontal cortex projecting to ventral tegmental area by a 5-HT1A receptor agonist
2005
Modulation of 5-HT1A receptor signalling by point-mutation of cysteine351 in the rat Gαo protein
1999
5-HT7 receptor mRNA expression in human trigeminal ganglia
2001
Relating protein pharmacology by ligand chemistry
2007 Standout
Chimaeric Gα proteins: their potential use in drug discovery
1999
Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design
2010
α2A-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice
2005
Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice
2003 StandoutNobel
Serotonin 5-HT6 Receptor Antagonists in Alzheimer’s Disease: Therapeutic Rationale and Current Development Status
2016
The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways
2003
Nondopaminergic mechanisms in levodopa‐induced dyskinesia
2005
IN VITRO EFFECTS OF ANTIPSYCHOTICS ON HUMAN PLATELET ADHESION AND AGGREGATION AND PLASMA COAGULATION
2007 StandoutNobel
Spreading depression: a review of the clinical relevance
2001
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats
2003
The Role of Cytokines in the Regulation of Neurotransmission
2008
The debate over dopamine’s role in reward: the case for incentive salience
2006 Standout
From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease
2010
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain
2001
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
2010 Standout
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
G Protein Activation by Human Dopamine D3 Receptors in High-Expressing Chinese Hamster Ovary Cells: A Guanosine-5′-O-(3-[35S]thio)-Triphosphate Binding and Antibody Study
1999
Molecular Aspects of Seed Dormancy
2008 Standout
Reciprocal autoreceptor and heteroreceptor control of serotonergic, dopaminergic and noradrenergic transmission in the frontal cortex: relevance to the actions of antidepressant agents
2000
Combination therapy in combating cancer
2017 Standout
The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors
2013
Serotonin-elicited inhibition of Cl−secretion in the rabbit conjunctival epithelium
2001
Synthesis and Structure−Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors
2004
Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care
2011 Standout
Evidence that the plant cannabinoid cannabigerol is a highly potent α2‐adrenoceptor agonist and moderately potent 5HT1Areceptor antagonist
2009
Functional Differences between Full and Partial Agonists: Evidence for Ligand-Specific Receptor Conformations
2001 StandoutNobel
BindingDB Entry 5280: S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine.
2012
Classics in Chemical Neuroscience: Aripiprazole
2017
SB‐224289–a novel selective (human) 5‐HT1B receptor antagonist with negative intrinsic activity
1998
GCR1 , the putative Arabidopsis G protein-coupled receptor gene is cell cycle-regulated, and its overexpression abolishes seed dormancy and shortens time to flowering
2002
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
Microglial M1/M2 polarization and metabolic states
2015 Standout
Abscisic Acid: Emergence of a Core Signaling Network
2010 Standout
Insights into ligand pharmacology using receptor–G-protein fusion proteins
2000
Prescribed drugs containing nitrogen heterocycles: an overview
2020 Standout
Hallucinogens
2004 Standout
Works of C. Chaput being referenced
Comparison of hippocampal G protein activation by 5-HT 1A receptor agonists and the atypical antipsychotics clozapine and S16924
2003
The 5HT1A receptor ligand, S15535, antagonises G-protein activation: a [35S]GTPγS and [3H]S15535 autoradiography study
1999
Actions of novel agonists, antagonists and antipsychotic agents at recombinant rat 5-HT6 receptors: A comparative study of coupling to Gαs
2008
Inhibition of the constitutive activity of human 5‐HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635
1997
Clozapine is a partial agonist at cloned, human serotonin 5-HT1A receptors
1996
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: Definition of its binding profile using agonists, antagonists and inverse agonists
1998
S 15535 and WAY 100,635 antagonise 5-HT-stimulated [35S]GTPγS binding at cloned human 5-HT1A receptors
1996
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a []GTPγS binding study
1998
[35S]–GTPγS autoradiography reveals α2 adrenoceptor-mediated G-protein activation in amygdala and lateral septum
2000
Agonist and Inverse Agonist Efficacy at Human Recombinant Serotonin 5-HT 1A Receptors as a Function of Receptor:G-protein Stoichiometry
1997
Dopamine D2 receptor-mediated G-protein activation in rat striatum: functional autoradiography and influence of unilateral 6-hydroxydopamine lesions of the substantia nigra
2001
Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy
1997
Actions of α2 adrenoceptor ligands at α2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for α2A adrenoceptors
1998
Down-regulation of rat β-adrenoceptors by clenbuterol or desipramine does not require chronic treatment: [3H]CGP-12177 binding reveals rapid (24 hour) modulation
1996
[35S]Guanosine-5′-O-(3-thio)triphosphate Binding as a Measure of Efficacy at Human Recombinant Dopamine D4.4Receptors: Actions of Antiparkinsonian and Antipsychotic Agents
1997
Pindolol antagonises G-protein activation at both pre- and postsynaptic serotonin 5-HT 1A receptors: a [ 35 S]GTP?S autoradiography study
2001