Citation Impact
Citing Papers
Antiseptics and Disinfectants: Activity, Action, and Resistance
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Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America
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Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
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Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
2012 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
An outbreak of extended-spectrum, β-lactamase-producing Salmonella senftenberg in a burns ward
1998
Infective Endocarditis
2005 Standout
Molecular Epidemiology of a Citywide Outbreak of Extended‐Spectrum β‐Lactamase–Producing Klebsiella pneumoniae Infection
2002
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1997
Opposing effect of Lactobacillus on in vitro Klebsiella pneumoniae in biofilm and in an in vivo intestinal colonisation model
2017
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
2008 Standout
OXA β-lactamases in Acinetobacter: the story so far
2005
Epidemiological typing of extended-spectrum β-lactamase-producing isolates by pulsed-field gel electrophoresis and antibiotic susceptibility patterns
1999
TEM-24 extended-spectrum β-lactamase-producing Enterobacter aerogenes: long-term clonal dissemination in French hospitals
2000
Chromosomally encoded cephalosporin-hydrolyzing β-lactamase of Proteus vulgaris RO104 belongs to Ambler's class A
1994
Beta-lactamase-mediated resistance and opportunities for its control
1998
A case-control study of an outbreak of infections caused by Klebsiella pneumoniae strains producing CTX-1 (TEM-3) beta-lactamase
1991
Molecular mechanisms of antibiotic resistance
2014 Standout
Characterisation of OXA-51, a novel class D carbapenemase found in genetically unrelated clinical strains of Acinetobacter baumannii from Argentina
2005
What's new in antibiotic resistance? Focus on beta-lactamases
2006
Prevalence of extended spectrum β-lactamase (ESBL)-producing clinical isolates in the Asia-Pacific region and South Africa: regional results from SENTRY Antimicrobial Surveillance Program (1998–99)
2002
In vitro antibacterial activity and mechanism of action of J-111,225, a novel 1β-methylcarbapenem, against transferable IMP-1 metallo-β-lactamase producers
2000
X-ray Analysis of the NMC-A β-Lactamase at 1.64-Å Resolution, a Class A Carbapenemase with Broad Substrate Specificity
1998
Origin and impact of plasmid-mediated extended-spectrum beta-lactamases
1994
Engineering and characterization of a superfolder green fluorescent protein
2005 Standout
Extended-Spectrum -Lactamase-Producing Escherichia coli and Klebsiella pneumoniae: Risk Factors for Infection and Impact of Resistance on Outcomes
2001
Spread of Extended‐Spectrum β‐Lactamase–ProducingKlebsiella pneumoniae: Are β‐Lactamase Inhibitors of Therapeutic Value?
1998
Antimicrobial-Drug Resistance
1996
Decreased transmission of Enterobacteriaceae with extended-spectrum β-lactamases in an intensive care unit by nursing reorganization
1995
Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance
2011 Standout
IRT and CMT β-lactamases and inhibitor resistance
2008
Melioidosis
2003 Standout
Trends in β‐Lactam Resistance Among Enterobacteriaceae
1998
Infection Control — A Problem for Patient Safety
2003 Standout
Determining the value of antimicrobial surveillance programs
2001
Understanding the longevity of the β-lactam antibiotics and of antibiotic/β-lactamase inhibitor combinations
2005
Epidemiological typing of extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates responsible for five outbreaks in a university hospital
1997
Infection Control in the ICU
2001
Outbreak of nosocomial infections due toKlebsiella pneumoniae producing SHV-4 beta-lactamase
1990
Aspartic acid for asparagine substitution at position 276 reduces susceptibility to mechanism-based inhibitors in SHV-1 and SHV-5 β-lactamases
1999
Biochemical analysis of the ceftazidime-hydrolysing extended-spectrum beta-lactamase CTX-M-15 and of its structurally related beta-lactamase CTX-M-3
2002
Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
2008 Standout
Ceftazidime-Resistant Klebsiella pneumoniae and Escherichia coli Bloodstream Infection: A Case-Control and Molecular Epidemiologic Investigation
1996
Plasmid-mediated TEM-3 extended-spectrum beta-lactamase production in Salmonella typhimurium in Casablanca
2002
Multiple Antibiotic–Resistant <EMPH TYPE="ITAL">Klebsiella</EMPH> and <EMPH TYPE="ITAL">Escherichia coli</EMPH> in Nursing Homes
1999
Clinical experience with single agent and combination regimens in the management of infection in the febrile neutropenic patient
1996
Antibacterial resistance worldwide: causes, challenges and responses
2004 Standout
The Science of Antibiotic Discovery
2020 Standout
Inhibitor resistant class A beta-lactamases
1999
Mechanisms of Bacterial Resistance to Antibiotics and Biocides
1998
Clinical inhibitor-resistant mutants of the β-lactamase TEM-1 at amino-acid position 69
1998
Ceftazidime-resistant Klebsiella pneumoniae bloodstream infection in children with febrile neutropenia
2000
OXA-type carbapenemases
2006
Tazobactam is a potent inactivator of selected inhibitor-resistant class A β-lactamases
2006
Ceftazidime-hydrolysing CTX-M-15 extended-spectrum beta-lactamase (ESBL) in Poland
2002
A novel extended-spectrum -lactamase CTX-M-23 with a P167T substitution in the active-site omega loop associated with ceftazidime resistance
2004
Outer membrane protein alterations and blaTEM-1 variants: their role in -lactam resistance in Klebsiella pneumoniae
2003
Clinical and Bacteriologic Epidemiology of Extended‐Spectrum s‐Lactamase –Producing Strains ofKlebsiella pneumoniaein a Medical Intensive Care Unit
1998
Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology
2006 Standout
Extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit: risk factors for infection and colonization
2003
Minor extended-spectrum β-lactamases
2008
Control of a Prolonged Outbreak of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in a University Hospital
1999
Selective digestive decontamination by erythromycin-base in a polyvalent intensive care unit
1993
In vivo acquisition of extended-spectrum beta-lactamase inSalmonella enteritidis during antimicrobial therapy
1995
Exposure to co-amoxiclav as a risk factor for co-amoxiclav-resistant Escherichia coli urinary tract infection
2002
Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria
2012
Genetic support and diversity of acquired extended-spectrum β-lactamases in Gram-negative rods
2012
Selective decontamination of the gastrointestinal tract as an infection control measure
1991
Inhibitor-resistant TEM -lactamases: phenotypic, genetic and biochemical characteristics
1999
Klebsiella pneumoniae infections in Greek hospitals. Dissemination of plasmids encoding an SHV-5 type β-lactamase
1995
The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit
2000 StandoutNobel
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Plasmid-mediated extended-spectrum β-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1
2001
Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: A review
2013 Standout
The challenge of emerging and re-emerging infectious diseases
2004 StandoutNature
Ceftriaxone-Resistant Salmonella Infection Acquired by a Child from Cattle
2000
The Asparagine to Aspartic Acid Substitution at Position 276 of TEM-35 and TEM-36 Is Involved in the β-Lactamase Resistance to Clavulanic Acid
1995
Molecular characterisation by PCR-restriction fragment length polymorphism of TEM β-lactamases
1995
Evolution of extended-spectrum β-lactamases by mutation
2008
Production of CTX-M-3 extended-spectrum beta-lactamase and IMP-1 metallo beta-lactamase by five Gram-negative bacilli: survey of clinical isolates from seven laboratories collected in 1998 and 2000, in the Kinki region of Japan
2003
Evolutionary Optimization of Computationally Designed Enzymes: Kemp Eliminases of the KE07 Series
2009 StandoutNobel
Extended-Spectrum β-Lactamase–ProducingEscherichia coliandKlebsiellaSpecies: Risk Factors for Colonization and Impact of Antimicrobial Formulary Interventions on Colonization Prevalence
2002
Evolution of CTX-M-type β-lactamases in isolates of Escherichia coli infecting hospital and community patients
2005
Characterisation of a unique ceftazidime-hydrolysing -lactamase, TEM-E2
1990
Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum β-lactamases
2004
Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death
2013 StandoutNobel
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
2015 Standout
Molecular epidemiology of an outbreak due to IRT-2 -lactamase-producing strains of Klebsiella pneumoniae in a geriatric department
2000
Pathogenesis of urinary tract infection
2000
Evolution and epidemiology of extended-spectrum β-lactamases (ESBLs) and ESBL-producing microorganisms
2001
Comparison of 8 vs 15 Days of Antibiotic Therapy for Ventilator-Associated Pneumonia in Adults
2003 Standout
Characterization of an SHV-5 related extended broad-spectrum beta-lactamase in enterobacteriaceae from western australia
1993
Plasmid-Mediated -Lactamase (TEM-7) Involved in Resistance to Ceftazidime and Aztreonam
1988
Atomic Resolution Structures of CTX-M β-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability
2005
Evaluation of penicillin-based inhibitors of the class A and B β-lactamases from Bacillus anthracis
2003
The pros, cons, and many unknowns of probiotics
2019 Standout
A 5-year epidemiological study of extended-spectrum betabeta-lactamase-producing Klebsiella pneumoniae isolates in a medium- and long-stay neurological unit
2000
Evaluation of the MicroScan ESBL plus confirmation panel for detection of extended-spectrum β-lactamases in clinical isolates of oxyimino-cephalosporin-resistant Gram-negative bacteria
2004
KEGG as a reference resource for gene and protein annotation
2015 Standout
EXTENDED-SPECTRUM β-LACTAMASES AND OTHER ENZYMES PROVIDING RESISTANCE TO OXYIMINO-β-LACTAMS
1997
Version 2000: the new β-lactamases of Gram-negative bacteria at the dawn of the new millennium
2000
An adaptive response of Enterobacter aerogenes to imipenem: regulation of porin balance in clinical isolates
2012
The New β-Lactamases
2005
Mechanisms of reduced susceptibility to amoxycillin-clavulanic acid in Escherichia coli strains from the health region of Tortosa (Catalonia, Spain)
2004
CTX-M: changing the face of ESBLs in Europe
2006
Ventilator-associated Pneumonia
2002 Standout
beta-Lactamases in laboratory and clinical resistance
1995
Genes Encoding TEM-4, SHV-2, and CTX-M-10 Extended-Spectrum β-Lactamases Are Carried by MultipleKlebsiella pneumoniaeClones in a Single Hospital (Madrid, 1989 to 2000)
2002
Outbreak of TEM-24-producing Enterobacter aerogenes in an intensive care unit and dissemination of the extended-spectrum beta-lactamase to other members of the family enterobacteriaceae
1996
Acinetobacter baumannii : Emergence of a Successful Pathogen
2008 Standout
Infections with NontyphoidalSalmonellaSpecies Producing TEM-63 or a Novel TEM Enzyme, TEM-131, in South Africa
2004
Characterization of a new TEM-derived beta-lactamase produced in a Serratia marcescens strain
1997
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Characterization of multiple-antibiotic-resistant Salmonella typhimurium stains: molecular epidemiology of PER-1-producing isolates and evidence for nosocomial plasmid exchange by a clone
1996
Epidemiology of Extended-Spectrum β-Lactamase-Producing Enterobacter Isolates in a Spanish Hospital during a 12-Year Period
2002
Variety of β-Lactamases Produced by Amoxicillin-Clavulanate-Resistant Escherichia coli Isolated in the Northeastern United States
2004
Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important beta-lactamases
1994
Molecular epidemiology of Klebsiella pneumoniae strains that produce SHV-4 beta-lactamase and which were isolated in 14 French hospitals
1994
Characterization of a Chromosomally Encoded Extended-Spectrum Class A β-Lactamase from Kluyvera cryocrescens
2001
New extended-spectrum TEM-type beta-lactamase from Salmonella enterica subsp. enterica isolated in a nosocomial outbreak
1995
Extended-spectrum beta-lactamases
1989 Standout
Resistance of enterococci to glycopeptides
1990
Analysis of Antibiotic Resistance Genes in Multidrug-Resistant Acinetobacter sp. Isolates from Military and Civilian Patients Treated at the Walter Reed Army Medical Center
2006
Sequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes
1993
Updated Functional Classification of β-Lactamases
2009 Standout
Plasmid-Mediated Resistance to Expanded-Spectrum Cephalosporins among Enterobacter aerogenes Strains
1998
Occurrence and detection of extended-spectrum beta-lactamases in members of the family Enterobacteriaceae at a veterans medical center: seek and you may find
1997
Survey of Klebsiella pneumoniae producing extended-spectrum beta-lactamases: prevalence of TEM-3 and first identification of TEM-26 in France
1996
Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M β-Lactamases
2005
Catalytic properties of class A β-lactamases: efficiency and diversity
1998
In vitro antimicrobial production of beta-lactamases, aminoglycoside-modifying enzymes, and chloramphenicol acetyltransferase by and susceptibility of clinical isolates of Acinetobacter baumannii
1993
Cefepime, Piperacillin-Tazobactam, and the Inoculum Effect in Tests with Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
2001
Molecular Basis of Bacterial Outer Membrane Permeability Revisited
2003 Standout
Outbreak of Ceftazidime-Resistant Klebsiella pneumoniae in a Pediatric Hospital in Warsaw, Poland: Clonal Spread of the TEM-47 Extended-Spectrum β-Lactamase (ESBL)-Producing Strain and Transfer of a Plasmid Carrying the SHV-5-Like ESBL-Encoding Gene
1998
Genetic and Functional Analysis of the Chromosome-Encoded Carbapenem-Hydrolyzing Oxacillinase OXA-40 ofAcinetobacter baumannii
2002
Resistance to β-Lactamase Inhibitor Protein Does Not Parallel Resistance to Clavulanic Acid in TEM β-Lactamase Mutants
2002
TEM-24 Produced by Four Different Species of Enterobacteriaceae , Including Providencia rettgeri , in a Single Patient
1999
Dissemination of Acinetobacter baumannii Clones with OXA-23 Carbapenemase in Colombian Hospitals
2007
Comparative study of a novel plasmid-mediated beta-lactamase, CAZ-2, and the CTX-1 and CAZ-1 enzymes conferring resistance to broad-spectrum cephalosporins
1988
Detection of extended-spectrum beta-lactamases in members of the family Enterobacteriaceae: comparison of the double-disk and three-dimensional tests
1992
Development of "oligotyping" for characterization and molecular epidemiology of TEM beta-lactamases in members of the family Enterobacteriaceae
1990
Inhibitor-resistant TEM (IRT) beta-lactamases with different substitutions at position 244
1997
Evidence of Interhospital Transmission of Extended-Spectrum β-Lactam-Resistant Klebsiella pneumoniae in the United States, 1986 to 1993
1997
Predicting Evolutionary Potential:In VitroEvolution Accurately Reproduces Natural Evolution of the TEM β-Lactamase
2002
TEM-103/IRT-28 β-Lactamase, a New TEM Variant Produced by Escherichia coli BM4511
2002
A natural polymorphism in β-lactamase is a global suppressor
1997
TEM-72, a New Extended-Spectrum β-Lactamase Detected in Proteus mirabilis and Morganella morganii in Italy
2000
Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America
2011 Standout
Phenotypic and Molecular Detection of CTX-M-β-Lactamases Produced by Escherichia coli and Klebsiella spp
2004
Epidemiological Survey of Amoxicillin-Clavulanate Resistance and Corresponding Molecular Mechanisms in Escherichia coli Isolates in France: New Genetic Features of bla TEM Genes
2000
Imipenem Resistance in a Salmonella Clinical Strain Due to Plasmid-Mediated Class A Carbapenemase KPC-2
2003
A Novel Complex Mutant β-Lactamase, TEM-68, Identified in a Klebsiella pneumoniae Isolate from an Outbreak of Extended-Spectrum β-Lactamase-Producing Klebsiellae
2000
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Diversity, Epidemiology, and Genetics of Class D β-Lactamases
2009
Growing Group of Extended-Spectrum β-Lactamases: the CTX-M Enzymes
2003
Can Results Obtained with Commercially Available MicroScan Microdilution Panels Serve as an Indicator of β-Lactamase Production among Escherichia coli and Klebsiella Isolates with Hidden Resistance to ExpandedSpectrum Cephalosporins and Aztreonam?
1998
Novel Fluorogenic Substrates for Imaging β-Lactamase Gene Expression
2003 StandoutNobel
New variant of TEM-10 beta-lactamase gene produced by a clinical isolate of proteus mirabilis
1995
More extended-spectrum beta-lactamases
1991
Investigation of a Nosocomial Outbreak of Imipenem-Resistant Acinetobacter baumannii Producing the OXA-23 β-Lactamase in Korea
2005
Characterization of Extended-Spectrum β-Lactamase-Producing Salmonella typhimurium by Phenotypic and Genotypic Typing Methods
1999
Nucleotide sequence of the SHV-5 beta-lactamase gene of a Klebsiella pneumoniae plasmid
1990
TEM-4, a new plasmid-mediated beta-lactamase that hydrolyzes broad-spectrum cephalosporins in a clinical isolate of Escherichia coli
1989
Emergence of Oxacillinase-Mediated Resistance to Imipenem inKlebsiella pneumoniae
2003
Pseudomonas pseudomallei resistance to beta-lactam antibiotics due to alterations in the chromosomally encoded beta-lactamase
1991
First Isolation of Metallo-β-Lactamase-Producing Multiresistant Klebsiella pneumoniae from a Patient in Brazil
2005
Prediction of the Evolution of Ceftazidime Resistance in Extended-Spectrum β-Lactamase CTX-M-9
2006
Piperacillin, tazobactam, and gentamicin alone or combined in an endocarditis model of infection by a TEM-3-producing strain of Klebsiella pneumoniae or its susceptible variant
1992
Plasmidic Extended-Spectrum β-Lactamases in Vibrio cholerae O1 El Tor Isolates in Argentina
2002
CTX-M-14, a Plasmid-Mediated CTX-M Type Extended-Spectrum β-Lactamase Isolated from Escherichia coli
2002
Extended-Spectrum β-Lactamases: a Clinical Update
2005 Standout
TEM-121, a Novel Complex Mutant of TEM-Type β-Lactamase from Enterobacter aerogenes
2004
Outbreak of ceftazidime resistance caused by extended-spectrum beta-lactamases at a Massachusetts chronic-care facility
1990
CTX-M-Type Extended-Spectrum β-Lactamase That Hydrolyzes Ceftazidime through a Single Amino Acid Substitution in the Omega Loop
2001
Cloning and Sequencing of the Gene Encoding Toho-2, a Class A β-Lactamase Preferentially Inhibited by Tazobactam
1998
Chromosome-Encoded Ambler Class A β-Lactamase of Kluyvera georgiana , a Probable Progenitor of a Subgroup of CTX-M Extended-Spectrum β-Lactamases
2002
β-Lactamases of Kluyvera ascorbata , Probable Progenitors of Some Plasmid-Encoded CTX-M Types
2002
Emerging Extended-Spectrum β-Lactamases in Proteus mirabilis
2002
Use of Microdilution Panels with and without β-Lactamase Inhibitors as a Phenotypic Test for β-Lactamase Production among Escherichia coli , Klebsiella spp., Enterobacter spp., Citrobacter freundii , and Serratia marcescens
1999
Selection and Characterization of β-Lactam–β-Lactamase Inactivator-Resistant Mutants following PCR Mutagenesis of the TEM-1 β-Lactamase Gene
1998
Novel plasmid-mediated beta-lactamase (TEM-10) conferring selective resistance to ceftazidime and aztreonam in clinical isolates of Klebsiella pneumoniae
1989
Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
2010 Standout
Molecular and Biochemical Characterization of SHV-56, a Novel Inhibitor-Resistant β-Lactamase fromKlebsiella pneumoniae
2008
Detection of Extended-Spectrum β-Lactamases in Clinical Isolates of Enterobacter cloacae and Enterobacter aerogenes
2000
In vitro activities of various beta-lactam antimicrobial agents against clinical isolates of Escherichia coli and Klebsiella spp. resistant to oxyimino cephalosporins
1995
Three Decades of β-Lactamase Inhibitors
2010 Standout
Ambler Class A Extended-Spectrum β-Lactamases in Pseudomonas aeruginosa : Novel Developments and Clinical Impact
2003
Prevalence of Clinical Isolates of Escherichia coli Producing Inhibitor-Resistant β-Lactamases at a University Hospital in Barcelona, Spain, over a 3-Year Period
2002
Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance
2001 Standout
Risk Factors for Recovery of Ampicillin-Sulbactam-Resistant Escherichia coli in Hospitalized Patients
2000
Genetic and Structural Insights into the Dissemination Potential of the Extremely Broad-Spectrum Class A β-Lactamase KPC-2 Identified in an Escherichia coli Strain and an Enterobacter cloacae Strain Isolated from the Same Patient in France
2008
Ceftazidime-Resistant Enterobacteriaceae Isolates from Three Polish Hospitals: Identification of Three Novel TEM- and SHV-5-Type Extended-Spectrum β-Lactamases
1998
Identification and Broad Dissemination of the CTX-M-14 β-Lactamase in Different Escherichia coli Strains in the Northwest Area of Spain
2002
Hospital outbreak of Klebsiella pneumoniae resistant to broad-spectrum cephalosporins and beta-lactam-beta-lactamase inhibitor combinations by hyperproduction of SHV-5 beta-lactamase
1996
Extended-Spectrum β-Lactamases in Klebsiella pneumoniae Bloodstream Isolates from Seven Countries: Dominance and Widespread Prevalence of SHV- and CTX-M-Type β-Lactamases
2003
The GenusAeromonas: Taxonomy, Pathogenicity, and Infection
2010 Standout
The Crisis in Antibiotic Resistance
1992 StandoutScience
Evolution of extended-spectrum beta-lactam resistance (SHV-8) in a strain of Escherichia coli during multiple episodes of bacteremia
1997
Epidemiological study by pulsed-field gel electrophoresis of an outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a geriatric hospital
1994
Outbreak of Carbapenem-Resistant Acinetobacter baumannii Producing the OXA-23 Enzyme in Curitiba, Brazil
2003
Outbreak of Infection Caused by Enterobacter cloacae Producing the Novel VEB-3 Beta-Lactamase in China
2005
Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure
1995
Epidemiology and Successful Control of a Large Outbreak Due to Klebsiella pneumoniae Producing ExtendedSpectrum β-Lactamases
1998
Molecular epidemiology of Klebsiella pneumoniae producing SHV-5 beta- lactamase: parallel outbreaks due to multiple plasmid transfer
1996
R-plasmid-encoded adhesive factor in Klebsiella pneumoniae strains responsible for human nosocomial infections
1992
Multiple substitutions at position 104 of β-lactamase TEM-1: assessing the role of this residue in substrate specificity
1995
TEM-89 β-Lactamase Produced by a Proteus mirabilis Clinical Isolate: New Complex Mutant (CMT 3) with Mutations in both TEM-59 (IRT-17) and TEM-3
2001
Genetics and Expression of the Carbapenem-Hydrolyzing Oxacillinase GeneblaOXA-23inAcinetobacter baumannii
2007
Nucleotide Sequence and Characterization of a Novel Cefotaxime-Hydrolyzing β-Lactamase (CTX-M-10) Isolated in Spain
2001
A functional classification scheme for beta-lactamases and its correlation with molecular structure
1995 Standout
Mutant TEM β-Lactamase Producing Resistance to Ceftazidime, Ampicillins, and β-Lactamase Inhibitors
2002
Genetic and Biochemical Characterization of a Chromosome-Encoded Carbapenem-Hydrolyzing Ambler Class D β-Lactamase fromShewanella algae
2004
Molecular Characterization of a Novel Plasmid-Encoded Cefotaximase (CTX-M-12) Found in Clinical Klebsiella pneumoniae Isolates from Kenya
2001
Construction and Characterization of Mutants of the TEM-1 β-Lactamase Containing Amino Acid Substitutions Associated with both Extended-Spectrum Resistance and Resistance to β-Lactamase Inhibitors
1999
Utility of NCCLS Guidelines for Identifying Extended-Spectrum β-Lactamases in Non- Escherichia coli and Non- Klebsiella spp. of Enterobacteriaceae
2004
Complete Nucleotide Sequence of a 92-Kilobase Plasmid Harboring the CTX-M-15 Extended-Spectrum Beta-Lactamase Involved in an Outbreak in Long-Term-Care Facilities in Toronto, Canada
2004
Sequence analysis of PER-1 extended-spectrum beta-lactamase from Pseudomonas aeruginosa and comparison with class A beta-lactamases
1994
A complex mutant of TEM-1 beta-lactamase with mutations encountered in both IRT-4 and extended-spectrum TEM-15, produced by an Escherichia coli clinical isolate
1997
Experimental Prediction of the Natural Evolution of Antibiotic Resistance
2003
How β-Lactamases Have Driven Pharmaceutical Drug Discovery
1998
Origins and Evolution of Antibiotic Resistance
2010 Standout
Transposition of the gene encoding a TEM-12 extended-spectrum beta-lactamase
1992
Silver Colloid Nanoparticles: Synthesis, Characterization, and Their Antibacterial Activity
2006 Standout
ColE1-Like Plasmid pIP843 of Klebsiella pneumoniae Encoding Extended-Spectrum β-Lactamase CTX-M-17
2002
Quantifying Nonspecific TEM β-Lactamase ( bla TEM ) Genes in a Wastewater Stream
2008
Cefotaxime-hydrolysing activity of the β-lactamase ofKlebsiella oxytocaD488 could be related to a threonine residue at position 140
1991
Kinetic Study of Two Novel Enantiomeric Tricyclic β-Lactams Which Efficiently Inactivate Class C β-Lactamases
2001
Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme
2017
Roles of β-Lactamases and Porins in Activities of Carbapenems and Cephalosporins against Klebsiella pneumoniae
1999
Countrywide Spread of CTX-M-3 Extended-Spectrum β-Lactamase-Producing Microorganisms of the Family Enterobacteriaceae in Poland
2002
SHV-49, a Novel Inhibitor-Resistant β-Lactamase in a Clinical Isolate of Klebsiella pneumoniae
2004
Coexistence of SHV-4- and TEM-24-Producing Enterobacter aerogenes Strains before a Large Outbreak of TEM-24-Producing Strains in a French Hospital
2001
Multiply resistant Klebsiella pneumoniae strains from two Chicago hospitals: identification of the extended-spectrum TEM-12 and TEM-10 ceftazidime-hydrolyzing beta-lactamases in a single isolate
1994
Three Cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China
2002
Resistance to cefotaxime and seven other beta-lactams in members of the family Enterobacteriaceae: a 3-year survey in France
1992
Multiplicity of TEM-derived beta-lactamases from Klebsiella pneumoniae strains isolated at the same hospital and relationships between the responsible plasmids
1989
Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli
1995
Emergence of an inhibitor-resistant beta-lactamase (SHV-10) derived from an SHV-5 variant
1997
Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance Threat
2001 Standout
Occurrence and Phenotypic Characteristics of Extended-Spectrum β-Lactamases among Members of the Family Enterobacteriaceae at the Tel-Aviv Medical Center (Israel) and Evaluation of Diagnostic Tests
2003
Diversity of CTX-M β-lactamases and their promoter regions fromEnterobacteriaceaeisolated in three Parisian hospitals
2002
The Lys234Arg Substitution in the Enzyme SHV-72 Is a Determinant for Resistance to Clavulanic Acid Inhibition
2008
Molecular Characterization of a TEM-21 β-Lactamase in a Clinical Isolate of Morganella morganii
1998
Chromosome-Encoded Ambler Class D β-Lactamase ofShewanella oneidensisas a Progenitor of Carbapenem-Hydrolyzing Oxacillinase
2003
Ceftazidime-Resistant Klebsiella pneumoniae and Escherichia coli Isolates Producing TEM-10 and TEM-43 β-Lactamases from St. Louis, Missouri
1998
Random amplified polymorphic DNA and plasmid analyses used in investigation of an outbreak of multiresistant Klebsiella pneumoniae
1995
Implication of Ile-69 and Thr-182 residues in kinetic characteristics of IRT-3 (TEM-32) beta-lactamase
1996
Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Strains Causing Nosocomial Outbreaks of Infection in the United Kingdom
1998
Structural Consequences of the Inhibitor-Resistant Ser130Gly Substitution in TEM β-Lactamase,
2005
Structural features related to hydrolytic activity against ceftazidime of plasmid-mediated SHV-type CAZ-5 beta-lactamase
1989
Works of C. Chanal being referenced
TEM-109 (CMT-5), a Natural Complex Mutant of TEM-1 β-Lactamase Combining the Amino Acid Substitutions of TEM-6 and TEM-33 (IRT-5)
2005
Frequency of inhibitor-resistant TEM β-lactamases in Escherichia coli isolates from urinary tract infections in Fran
1994
Frequency and diversity of Class A extended-spectrum β-lactamases in hospitals of the Auvergne, France: a 2 year prospective study
2004
Susceptibility of new β-lactams to the expanded-spectrum β-lactamase CTX-1
1989
Comparative in-vitro activity of meropenem against clinical isolates including Enterobacteriaceae with expanded-spectrum -lactamases
1989
Interactions of meropenera, with -lactamases, including enzymes with extended-spectrum activity against third-generation cephalosporins
1989
Clinical isolates of Escherichia coli producing multiple TEM mutants resistant to β-lactamase inhibitors
1994
Characterization of an inhibitor-resistant enzyme IRT-2 derived from TEM-2 β-lactamase produced by Proteus mirabilis strains
1996
Comparative study of five plasmid-mediated ceftazidimases isolated in Klebsiella pneumoniae
1989
Klebsiella pneumoniae and Other Enterobacteriaceae Producing Novel Plasmid-Mediated -Lactamases Markedly Active Against Third-Generation Cephalosporins: Epidemiologic Studies
1988
Survey of prevalence of extended spectrum β-lactamases among Enterobacteriaceae
1996
Virulence genotype and nematode-killing properties of extra-intestinal Escherichia coli producing CTX-M β-lactamases
2006
Diversity of TEM Mutants in Proteus mirabilis
1999
Prevalence of β-Lactamases among 1,072 Clinical Strains of Proteus mirabilis : a 2-Year Survey in a French Hospital
2000
Prospective survey of colonization and infection caused by expanded-spectrum-beta-lactamase-producing members of the family Enterobacteriaceae in an intensive care unit
1989
Sequences of CAZ-3 and CTX-2 extended-spectrum beta-lactamase genes
1994
A Novel CTX-M β-Lactamase (CTX-M-8) in Cefotaxime-Resistant Enterobacteriaceae Isolated in Brazil
2000
CTX-M-1, CTX-M-3, and CTX-M-14 β-Lactamases from Enterobacteriaceae Isolated in France
2002
[Detection of beta-lactamases resistant to inhibitors (IRT) by the disk diffusion method].
1995
A Novel Class A Extended-Spectrum β-Lactamase (BES-1) in Serratia marcescens Isolated in Brazil
2000
Nucleotide sequences of CAZ-2, CAZ-6, and CAZ-7 beta-lactamase genes
1992
Unexpected Enzyme TEM-126: Role of Mutation Asp179Glu
2005
Chromosome-Encoded Class D β-Lactamase OXA-23 in Proteus mirabilis
2002
TEM Derivative-Producing Enterobacter aerogenes Strains: Dissemination of a Prevalent Clone
2002
Identification of CTX-2, a novel cefotaximase from a Salmonella mbandaka isolate
1991
Effects of Ser130Gly and Asp240Lys Substitutions in Extended-Spectrum β-Lactamase CTX-M-9
2003
Molecular characterization of nine different types of mutants among 107 inhibitor-resistant TEM beta-lactamases from clinical isolates of Escherichia coli
1995
Translocation of antibiotic resistance determinants including an extended-spectrum beta-lactamase between conjugative plasmids of Klebsiella pneumoniae and Escherichia coli
1991
Extended-Spectrum β-Lactamase TEM-24 in an Aeromonas Clinical Strain: Acquisition from the Prevalent Enterobacter aerogenes Clone inFrance
2003
Novel Cefotaximase (CTX-M-16) with Increased Catalytic Efficiency Due to Substitution Asp-240→Gly
2001
A 1998 Survey of Extended-Spectrum β-Lactamases in Enterobacteriaceae in France
2000
First characterization of inhibitor-resistant TEM (IRT) beta-lactamases in Klebsiella pneumoniae strains
1995