Standout Papers
Citation Impact
Citing Papers
Machine learning-assisted directed protein evolution with combinatorial libraries
2019 Nobel
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects
2019
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
2010 StandoutNobel
A point‐charge force field for molecular mechanics simulations of proteins based on condensed‐phase quantum mechanical calculations
2003 Standout
Inducible and reversible phenotypes in a novel mouse model of Friedreich’s Ataxia
2017
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
A statistical framework for analyzing deep mutational scanning data
2017
Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing
2013 StandoutNobel
Origin of the sequence‐dependent polyproline II structure in unfolded peptides
2005
Multistate and functional protein design using RoseTTAFold sequence space diffusion
2024 StandoutNobel
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Molecular imaging in living subjects: seeing fundamental biological processes in a new light
2003 Standout
Intrinsically unstructured proteins and their functions
2005 Standout
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Empirical force‐field assessment: The interplay between backbone torsions and noncovalent term scaling
2005
RNA targeting with CRISPR–Cas13
2017 Nature
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Polyproline II helix is the preferred conformation for unfolded polyalanine in water
2004
Complete mapping of viral escape from neutralizing antibodies
2017
Exploring the Helix-Coil Transition via All-Atom Equilibrium Ensemble Simulations
2005
Gut microbiome alterations in Alzheimer’s disease
2017 Standout
Host‐guest scale of left‐handed polyproline II helix formation
2003
Electrical contacts to one- and two-dimensional nanomaterials
2011
Comparison of multiple Amber force fields and development of improved protein backbone parameters
2006 Standout
Early Collapse is not an Obligate Step in Protein Folding
2004
Comparison of a QM/MM force field and molecular mechanics force fields in simulations of alanine and glycine “dipeptides” (Ace‐Ala‐Nme and Ace‐Gly‐Nme) in water in relation to the problem of modeling the unfolded peptide backbone in solution
2003
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Mutation effects predicted from sequence co-variation
2017
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Investigations into Sequence and Conformational Dependence of Backbone Entropy, Inter-basin Dynamics and the Flory Isolated-pair Hypothesis for Peptides
2003
The Unfolded State of the Villin Headpiece Helical Subdomain: Computational Studies of the Role of Locally Stabilized Structure
2006
Exploring sequence space: harnessing chemical and biological diversity towards new peptide leads
2017
Side‐chain entropy effects on protein secondary structure formation
2005
Local and macroscopic electrostatic interactions in single α-helices
2015
Structures of the first and second double‐stranded RNA‐binding domains of human TAR RNA‐binding protein
2010
Close agreement between the orientation dependence of hydrogen bonds observed in protein structures and quantum mechanical calculations
2004 StandoutNobel
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Near-native structure refinement using in vacuo energy minimization
2007 StandoutNobel
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Molecular Recognition of Protein Surfaces: High Affinity Ligands for the CBP KIX Domain
2003
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
2018 StandoutScience
Electrostatics significantly affect the stability of designed homeodomain variants
2002
Helix, Sheet, and Polyproline II Frequencies and Strong Nearest Neighbor Effects in a Restricted Coil Library
2005
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
α-Helical stabilization by side chain shielding of backbone hydrogen bonds
2002
Tripeptides Adopt Stable Structures in Water. A Combined Polarized Visible Raman, FTIR, and VCD Spectroscopy Study
2002
A Strategy for the Selective Imaging of Glycans Using Caged Metabolic Precursors
2010 StandoutNobel
Wavelength-selective cleavage of photoprotecting groups: strategies and applications in dynamic systems
2015 StandoutNobel
Fully Printed Separated Carbon Nanotube Thin Film Transistor Circuits and Its Application in Organic Light Emitting Diode Control
2011
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Density Functional Theory Study of the Cooperativity of Hydrogen Bonds in Finite and Infinite α-Helices
2003
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
One-Dimensional Electrical Contact to a Two-Dimensional Material
2013 StandoutScience
Two Dimensional Chiral Networks Emerging from the Aryl−F···H Hydrogen-Bond-Driven Self-Assembly of Partially Fluorinated Rigid Molecular Structures
2008 StandoutNobel
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
DeMaSk: a deep mutational scanning substitution matrix and its use for variant impact prediction
2020
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Carbon Nanotubes: Present and Future Commercial Applications
2013 StandoutScience
The Conformation of Tetraalanine in Water Determined by Polarized Raman, FT-IR, and VCD Spectroscopy
2004
Caged compounds for multichromic optical interrogation of neural systems
2014
MagicWand: A Single, Designed Peptide That Assembles to Stable, Ordered α-Helical Fibers
2008
RNA Scanning of a Molecular Machine with a Built-in Ruler
2016 StandoutNobel
Polyproline II propensities from GGXGG peptides reveal an anticorrelation with β-sheet scales
2005
DNA-Based Asymmetric Catalysis: Sequence-Dependent Rate Acceleration and Enantioselectivity
2008 StandoutNobel
Statistical coil model of the unfolded state: Resolving the reconciliation problem
2005
Imaging Cell Surface Glycans with Bioorthogonal Chemical Reporters
2007 StandoutNobel
The 3D profile method for identifying fibril-forming segments of proteins
2006 StandoutNobel
A Preference for Edgewise Interactions between Aromatic Rings and Carboxylate Anions: The Biological Relevance of Anion−Quadrupole Interactions
2007
Constrained Peptides as Miniature Protein Structures
2012
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments
2003
Using deep mutational scanning to benchmark variant effect predictors and identify disease mutations
2020
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
2006 StandoutNobel
Redox Control of the Binding Modes of an Organic Receptor
2015 StandoutNobel
Real-Time Bioluminescence Imaging of Glycans on Live Cells
2010 StandoutNobel
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Works of C. Anders Olson being referenced
Polyproline II structure in a sequence of seven alanine residues
2002
High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution
2014
Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality
2015
Interactions between the microbiota, immune and nervous systems in health and disease
2017 Standout
Recombinant Probes for Visualizing Endogenous Synaptic Proteins in Living Neurons
2013
Cooperative helix stabilization by complex Arg–Glu salt bridges
2001
Stabilization of α-helix structure by polar side-chain interactions: Complex salt bridges, cation–π interactions, and C–H … O H-bonds
2001
Single‐Round, Multiplexed Antibody Mimetic Design through mRNA Display
2012
A Comprehensive Biophysical Description of Pairwise Epistasis throughout an Entire Protein Domain
2014
A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity
2014
Adaptation in protein fitness landscapes is facilitated by indirect paths
2016
Importance of Controlling Nanotube Density for Highly Sensitive and Reliable Biosensors Functional in Physiological Conditions
2010
Cation−π Interaction in Model α-Helical Peptides
2002
Label-Free, Electrical Detection of the SARS Virus N-Protein with Nanowire Biosensors Utilizing Antibody Mimics as Capture Probes
2009
Alanine Is an Intrinsic α-Helix Stabilizing Amino Acid
1999
Human biodistribution and dosimetry of the SPECT benzodiazepine receptor radioligand iodine-123-iomazenil.
1994