Citation Impact
Citing Papers
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent
2010
Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis
2014 Science
Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis
2015
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category
2008
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
2003 Standout
Dendritic Cells Amplify T Cell-Mediated Immune Responses in the Central Nervous System
2006
Gut Microbiota Regulates K/BxN Autoimmune Arthritis through Follicular Helper T but Not Th17 Cells
2016
Expression and regulation of interleukin‐10 and interleukin‐10 receptor in rat astroglial and microglial cells
2002
IFN-γ-induced Th1-Treg polarization in inflamed brains limits exacerbation of experimental autoimmune encephalomyelitis
2024
Signal Transduction Inhibition of APCs Diminishes Th17 and Th1 Responses in Experimental Autoimmune Encephalomyelitis
2009
Enteric Flora Expands Gut Lamina Propria CX3CR1+ Dendritic Cells Supporting Inflammatory Immune Responses under Normal and Inflammatory Conditions
2010
Microbial Challenge Promotes the Regenerative Process of the Injured Central Nervous System of the Medicinal Leech by Inducing the Synthesis of Antimicrobial Peptides in Neurons and Microglia,
2008
IL-23 Is Critical in the Induction but Not in the Effector Phase of Experimental Autoimmune Encephalomyelitis
2007
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis
2018 StandoutNobel
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
2017
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells
2010
IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation
2016
Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation
2014
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
2018
Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain
2009
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells
2015
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
2009 Nature
The Lifespan and Turnover of Microglia in the Human Brain
2017
Interleukin-12: A Cytokine at the Interface of Inflammation and Immunity
1998
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
2014
Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses
2013
Regulatory T Cells Control VEGF-Dependent Skin Inflammation
2008
Parenchymal Microglia of Naıve Adult C57BL/6J Mice Express High Levels of B7.1, B7.2, and MHC Class II
2002
Transcriptomic profiling of microglia and astrocytes throughout aging
2020
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Migration of dendritic cells into the brain in a mouse model of prion disease
2005
Regulation and Function of Class II Major Histocompatibility Complex, CD40, and B7 Expression in Macrophages and Microglia: Implications in Neurological Diseases
2002
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
The AP-1 transcription factor Batf controls TH17 differentiation
2009 Nature
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
2007 Standout
Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis
2009
Inflammation and metabolic disorders
2006 StandoutNature
Mass Cytometry: Single Cells, Many Features
2016
The IL-23–IL-17 immune axis: from mechanisms to therapeutic testing
2014
Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis
2016
Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
2006
Microglia can be induced by IFN-γ or IL-4 to express neural or dendritic-like markers
2007
Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease
2006
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation
2005
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Microglial clearance function in health and disease
2008
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Induction and molecular signature of pathogenic TH17 cells
2012
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
A Rose by Any Other Name? The Potential Consequences of Microglial Heterogeneity During CNS Health and Disease
2007
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
2012 Nature
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
2009
The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease
2007
Toll-like receptors in neurodegeneration
2008
Interleukin-12 and the regulation of innate resistance and adaptive immunity
2003 Standout
TH17 cells in development: an updated view of their molecular identity and genetic programming
2008
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
2003 StandoutNature
Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection
2007
Microglial brain region−dependent diversity and selective regional sensitivities to aging
2016
Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
2014
Astrocytes and Microglia as Major Players of Myelin Production in Normal and Pathological Conditions
2020
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
IL‐21 and IL‐21R are not required for development of Th17 cells and autoimmunity in vivo
2008
CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ TH-17 cells in relapsing EAE
2007
Interferon‐γ differentially modulates the release of cytokines and chemokines in lipopolysaccharide‐ and pneumococcal cell wall‐stimulated mouse microglia and macrophages
2002
IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system
2011
A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
2008
Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
2018
Interleukin-10 and Interleukin refeceptor-I Are Upregulated in Glial Cells After an Excitotoxic Injury to the Postnatal Rat Brain
2009
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
2013 Nature
The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
2011
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
2020
Inflammatory processes in the aging mouse brain: Participation of dendritic cells and T-cells
2006
Phagocytosis of apoptotic cells in homeostasis
2015
The microglial "activation" continuum: from innate to adaptive responses
2005
From JNK to Pay Dirt: Jun Kinases, their Biochemistry, Physiology and Clinical Importance
2005
Patients with Chronic Mucocutaneous Candidiasis Exhibit Reduced Production of Th17-Associated Cytokines IL-17 and IL-22
2008
An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses
2015
CXCR3-Dependent Microglial Recruitment Is Essential for Dendrite Loss after Brain Lesion
2004
Lipopolysaccharide/interferon-gamma and not transforming growth factor beta inhibits retinal microglial migration from retinal explant
2003
Induction and effector functions of TH17 cells
2008 Nature
Divergent effects of IL‐12 and IL‐23 on the production of IL‐17 by human T cells
2006
Biology of interleukin-22
2010
Inflammation, stress, and diabetes
2005 Standout
Type 2 diabetes as an inflammatory disease
2011 Standout
JunB is essential for IL-23-dependent pathogenicity of Th17 cells
2017
Multiple sclerosis
2008 Standout
Heterogeneous expression of the triggering receptor expressed on myeloid cells‐2 on adult murine microglia
2002
Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis
2007
Cytosolic RIG-I–like helicases act as negative regulators of sterile inflammation in the CNS
2011
The c-jun kinase/stress-activated pathway: Regulation, function and role in human disease
2007
Regulation of the immune response by stress‐activated protein kinases
2009
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
2007
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
2006
Differentiation and function of Th17 T cells
2007
Factors regulating microglia activation
2013
Involvement of IL-9 in Th17-Associated Inflammation and Angiogenesis of Psoriasis
2013
Psoriasis
2015 Standout
NG2 proteoglycan‐expressing microglia as multipotent neural progenitors in normal and pathologic brains
2006
Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis
2005
Toll-like Receptors in Defense and Damage of the Central Nervous System
2007
Mitochondrial ligand inhibits store‐operated calcium influx and COX‐2 production in human microglia
2006
Microglial Recruitment, Activation, and Proliferation in Response to Primary Demyelination
2007
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis
2005
Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
2005
Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions
2015
Choreographing Immunity in the Skin Epithelial Barrier
2019
Lipid signalling in disease
2008
Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human Primates
2010
Region‐specific expression of immunoregulatory proteins on microglia in the healthy CNS
2008
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Host microbiota constantly control maturation and function of microglia in the CNS
2015 Standout
How microorganisms tip the balance between interleukin-12 family members
2007
Microglia in the Cerebral Wall of the Human Telencephalon at Second Trimester
2004
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
2013 Standout
Interleukin-4-inhibited mRNA expression in mixed rat glial and in isolated microglial cultures
2000
Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expression
2002
RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
2011
Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis
2006
Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis
2012
The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calcium level
2004
The IL-1 family: regulators of immunity
2010
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
2013
Regulatory T Cells Reinforce Intestinal Homeostasis
2009
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
2008 Standout
Thrombin induces IL-10 production in microglia as a negative feedback regulator of TNF-α release
2002
A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes
2007
Manifestation of Spontaneous and Early Autoimmune Gastritis in CCR7-Deficient Mice
2011
Janus faces of microglia in multiple sclerosis
2007
Distribution, markers, and functions of retinal microglia
2002
Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells
2015
Proteomic fingerprints distinguish microglia, bone marrow, and spleen macrophage populations
2005
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling
2010
CNS dendritic cells: Critical participants in CNS inflammation?
2006
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
2010
CD14 expression by activated parenchymal microglia/macrophages and infiltrating monocytes following human traumatic brain injury
2002
Migration of Perilesional Microglia after Focal Brain Injury and Modulation by CC Chemokine Receptor 5: AnIn SituTime-Lapse Confocal Imaging Study
2005
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Functional Specialization of Interleukin-17 Family Members
2011 Standout
Mass cytometry: blessed with the curse of dimensionality
2016
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
2017
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Anatomy of the brain neurogenic zones revisited: Fractones and the fibroblast/macrophage network
2002
Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells
2012
A Mass Spectrometric-Derived Cell Surface Protein Atlas
2015
Differential gene expression in LPS/IFNγ activated microglia and macrophages: in vitro versus in vivo
2009
Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives
2017
Insulin resistance and atherosclerosis
2006
Oncofetal reprogramming in tumour development and progression
2022
Cytokines, chemokines, and cytokine receptors in human microglia
2002
Protective and pathogenic functions of macrophage subsets
2011 Standout
Relationship of Apolipoprotein E and Age at Onset to Parkinson Disease Neuropathology
2006
Angiotensin II Controls Occludin Function and Is Required for Blood–Brain Barrier Maintenance: Relevance to Multiple Sclerosis
2007
Infiltrative microgliosis: activation and long-distance migration of subependymal microglia following periventricular insults.
2005
Early and Rapid Engraftment of Bone Marrow-Derived Microglia in Scrapie
2006
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
2009
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
2008
Stop the killing of beneficial bacteria
2011 Nature
Microglia and multiple sclerosis
2005
c-Jun N-terminal kinases as potential therapeutic targets
2007
Chapter 5 Emergence of the Th17 Pathway and Its Role in Host Defense
2008
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway
2010
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
2017
Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like Skin Inflammation in Mice
2013
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity
2013
Clinical relevance of tumour-associated macrophages
2022
Microglial cells kill prion-damaged neurons in vitro by a CD14 dependent process
2005
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Challenge with innate and protein antigens induces CCR7 expression by microglia in vitro and in vivo
2006
Motility and Ramification of Human Fetal Microglia in Culture: An Investigation Using Time-Lapse Video Microscopy and Image Analysis
2002
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
2008 Standout
Differential activation of microglia in neurogenic versus non‐neurogenic regions of the forebrain
2006
Modulation of experimental autoimmune encephalomyelitis by endogenous Annexin A1
2009
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
2018
The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms
2005
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain
2008 StandoutNobel
FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS
2014
Limited sufficiency of antigen presentation by dendritic cells in models of central nervous system autoimmunity
2010
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses
2013
Localizing central nervous system immune surveillance: Meningeal antigen‐presenting cells activate T cells during experimental autoimmune encephalomyelitis
2008
Microglia as a source and target of cytokines
2002
Cannabinoid and cannabinoid‐like receptors in microglia, astrocytes, and astrocytomas
2010
In Vivo Induction of Cutaneous Inflammation Results in the Accumulation of Extracellular Trap-Forming Neutrophils Expressing RORγt and IL-17
2013
Free Fatty Acids Induce a Proinflammatory Response in Islets via the Abundantly Expressed Interleukin-1 Receptor I
2009
Microglial Physiology: Unique Stimuli, Specialized Responses
2009
Restricted Microbiota and Absence of Cognate TCR Antigen Leads to an Unbalanced Generation of Th17 Cells
2010
The Subendothelial Extracellular Matrix Modulates JNK Activation by Flow
2009
Palmitoylethanolamide Increases after Focal Cerebral Ischemia and Potentiates Microglial Cell Motility
2003
Isolation and Culture of Microglia
2018
The Antigen-Presenting Activity of Fresh, Adult Parenchymal Microglia and Perivascular Cells from Retina
2004
Increased Interleukin (IL)-1β Messenger Ribonucleic Acid Expression in β-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1β in Human Islets by Glucose and Autostimulation
2008
The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin
2011
What is the blood–brain barrier (not)?
2006
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis
2006 Standout
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
2005 Standout
Fms-Like Tyrosine Kinase 3 Ligand Recruits Plasmacytoid Dendritic Cells to the Brain
2006
Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8+ T cell response
2018
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
2009
Early infancy microbial and metabolic alterations affect risk of childhood asthma
2015 Standout
IL-17 and Th17 Cells
2009 Standout
Dendritic Cells in Multiple Sclerosis Lesions: Maturation Stage, Myelin Uptake, and Interaction With Proliferating T Cells
2006
Therapeutic Targeting of the Tumor Microenvironment
2021
Acute in vivo exposure to interferon-γ enables resident brain dendritic cells to become effective antigen presenting cells
2009
Induction of Experimental Autoimmune Encephalomyelitis in IL-12 Receptor-β2-Deficient Mice: IL-12 Responsiveness Is Not Required in the Pathogenesis of Inflammatory Demyelination in the Central Nervous System
2003
Immunological and Inflammatory Functions of the Interleukin-1 Family
2009 Standout
IL-17 Family Cytokines and the Expanding Diversity of Effector T Cell Lineages
2007 Standout
The role of dendritic cells in neurodegenerative diseases.
2002
Early life antibiotic‐driven changes in microbiota enhance susceptibility to allergic asthma
2012
JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
2010
Islet Inflammation Impairs the Pancreatic β-Cell in Type 2 Diabetes
2009
System xc− and Glutamate Transporter Inhibition Mediates Microglial Toxicity to Oligodendrocytes
2007
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Inflammatory Bowel Disease
2010 Standout
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination
2002
CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response
2013
Microglial Phagocytosis of Apoptotic Inflammatory T Cells Leads to Down-Regulation of Microglial Immune Activation
2001
Islet Inflammation in Type 2 Diabetes
2008
Conditional stability of T cells
2010 StandoutNatureNobel
Innate lymphoid cells: A new paradigm in immunology
2015 Science
TLR Signaling Tailors Innate Immune Responses in Human Microglia and Astrocytes
2005
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
2006
Regulation of interleukin-12 production in antigen-presenting cells
2001
CD40 Expression by Microglial Cells Is Required for Their Completion of a Two-Step Activation Process during Central Nervous System Autoimmune Inflammation
2006
IFN-gamma and LPS-mediated IL-10-dependent suppression of retinal microglial activation.
2000
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
Randomized phase 1b trial of MOR103, a human antibody to GM-CSF, in multiple sclerosis
2015
Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration
2003
Vasoactive intestinal peptide and pituitary adenylate cyclase‐activating polypeptide inhibit chemokine production in activated microglia
2002
Cluster stability in the analysis of mass cytometry data
2016
Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy
2015
Platinum‐conjugated antibodies for application in mass cytometry
2015
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
Regulatory T cells in inflammatory skin disease: from mice to humans
2019
The Toll-Like Receptor TLR4 Is Necessary for Lipopolysaccharide-Induced Oligodendrocyte Injury in the CNS
2002
Physiology of Microglia
2011 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Works of Burkhard Becher being referenced
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells
2012
IL-9 as a mediator of Th17-driven inflammatory disease
2009
IL-22 Is Expressed by Th17 Cells in an IL-23-Dependent Fashion, but Not Required for the Development of Autoimmune Encephalomyelitis
2007
Building a zoo of mice for genetic analyses: A comprehensive protocol for the rapid generation of BAC transgenic mice
2010
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice
2008
Caspase 8 expression and signaling in Fas injury-resistant human fetal astrocytes
2001
Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex
2014
B-cells need a proper house, whereas T-cells are happy in a cave: the dependence of lymphocytes on secondary lymphoid tissues during evolution
2010
Expression of a homologue of rat NG2 on human microglia
1999
Interleukin 18–independent engagement of interleukin 18 receptor-α is required for autoimmune inflammation
2006
GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage
2015
PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis
1997
Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells
2011
Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain
2006
APC-derived cytokines and T cell polarization in autoimmune inflammation
2007
Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes
2020
Expression of the activation marker urokinase plasminogen-activator receptor in cultured human central nervous system microglia
1996
Neo-Lymphoid Aggregates in the Adult Liver Can Initiate Potent Cell-Mediated Immunity
2009
Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro.
1996
Fas expression on human fetal astrocytes without susceptibility to fas-mediated cytotoxicity
1998
C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages
2015
RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
2011
B7 Expression and Antigen Presentation by Human Brain Endothelial Cells: Requirement for Proinflammatory Cytokines
2000
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice
2012
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
2007
Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia
1996
The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity
2015
Innate and adaptive immune responses in the CNS
2015
Regulation of CD14 expression on human adult central nervous system-derived microglia
1996
Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12
2002
Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System
2008
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
2005
IL-10 PRODUCTION BY ADULT HUMAN DERIVED MICROGLIAL CELLS
1996
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
2005
High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease
2018
RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F
2008
Sall1 is a transcriptional regulator defining microglia identity and function
2016
TH17 cytokines in autoimmune neuro-inflammation
2011
IL-12 initiates tumor rejection via lymphoid tissue–inducer cells bearing the natural cytotoxicity receptor NKp46
2010
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
2007
Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation
2018
High-dimensional analysis of the murine myeloid cell system
2014
CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNS
2000
Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells
2014
Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia
2012
IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis
2003
Regulation of CD14 expression on human adult central nervous system‐derived microglia
1996
The Clinical Course of Experimental Autoimmune Encephalomyelitis and Inflammation Is Controlled by the Expression of Cd40 within the Central Nervous System
2001
Th17 Cells in Autoimmune Disease: Changing the Verdict
2009
The Fas pathway is involved in pancreatic β cell secretory function
2007
Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12
2002
Brain-immune connection: Immuno-regulatory properties of CNS-resident cells
2000
Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia
1996
Langerin neg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice
2013
Requirement of JNK2 for Scavenger Receptor A-Mediated Foam Cell Formation in Atherogenesis
2004 Science
IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis
2003
The end of gating? An introduction to automated analysis of high dimensional cytometry data
2015
Brain-immune connection: Immuno-regulatory properties of CNS-resident cells
2000
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
2016
Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell–mediated glioma rejection
2013