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Facilitatory and inhibitory transmitters modulate calcium influx during action potentials in Aplysia sensory neurons
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1994
Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat
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Indirect effects of intrathecal morphine upon diffuse noxious inhibitory controls (DNICs) in the rat
1986
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1996
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1998
Glycine and GABAA antagonists reduce the inhibition of primate spinothalamic tract neurons produced by stimulation in periaqueductal gray
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1990
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2001
Quinpirole-Induced Alterations of Tail Temperature Appear as Hyperalgesia in the Radiant Heat Tail-Flick Test
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1993
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1994
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1990
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1979
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1987
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Cellular site of opiate dependence
1980 Nature
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1988
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Immunocytochemistry with internally labeled monoclonal antibodies.
1982 StandoutNobel
Opioid actions on single nucleus raphe magnus neurons from rat and guinea‐pig in vitro.
1990
The origin of descending pathways in the dorsolateral funiculus of the spinal cord of the cat and rat: Further studies on the anatomy of pain modulation
1979
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1988
α2-Adrenoceptors Modulate NMDA-Evoked Responses of Neurons in Superficial and Deeper Dorsal Horn of the Medulla
1998
Synaptic Plasticity and the Modulation of the Ca2+ Current
1980 StandoutNobel
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Changes in nociception after lesions of descending serotonergic pathways induced with 5,6-dihydroxytryptamine
1985
Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides
1990 StandoutScience
5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system.
1989 StandoutNobel
Interaction between metabotropic and NMDA glutamate receptors in the periaqueductal grey pain modulatory system
2001
Serotonergic modulation of the responses to excitatory amino acids of rat dorsal horn neurons in vitro: implications for somatosensory transmission
1998
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Antinociception induced by local injections of carbachol into the nucleus raphe magnus in rats: Alteration by intrathecal injection of monoaminergic antagonists
1986
Midbrain Periaqueductal Gray (PAG) Inhibits Nociceptive Inputs to Sacral Dorsal Horn Nociceptive Neurons Through α2-Adrenergic Receptors
1998
The actions of noradrenaline on neurones of the rat substantia gelatinosa in vitro.
1984
Descending serotonergic, peptidergic and cholinergic pathways from the raphe nuclei: A multiple transmitter complex
1983
Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system.
1981
Attenuation of morphine-induced analgesia by p-chlorophenylalanine and p-chloroamphetamine: Test-dependent effects and evidence for brainstem 5-hydroxytryptamine involvement
1983
Serotonin Increases the Incidence of Primary Afferent-Evoked Long-Term Depression in Rat Deep Dorsal Horn Neurons
2001
Response of serotonin-containing neurons in nucleus raphe magnus to morphine, noxious stimuli, and periaqueductal gray stimulation in freely moving cats
1985
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
How do you feel? Interoception: the sense of the physiological condition of the body
2002 Standout
Presynaptic inhibition in Aplysia involves a decrease in the Ca2+ current of the presynaptic neuron.
1980 StandoutNobel
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors
1985 Standout
The dorsal raphe: An important nucleus in pain modulation
1994
The electron microscopic localization of methionine-enkephalin within the superficial layers (I and II) of the spinal cord
1980
Spinal and Supraspinal Factors in Human Muscle Fatigue
2001 Standout
Pharmacological antagonism of the antinociceptive effects of serotonin in the rat spinal cord
1983
The Thermal Grill Illusion: Unmasking the Burn of Cold Pain
1994 StandoutScience
The neuropsychology and neuropharmacology of the dorsal ascending noradrenergic bundle—a review
1980
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
α2-Adrenoceptor modulation of nociception in rat spinal cord: location, effects and interactions with morphine
1987
Chapter 11 Neurochemistry and neural circuitry in the dorsal horn
1986
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Lumbar intrathecal naloxone blocks analgesia produced by microstimulation of the ventromedial medulla in the rat
1982
Morphine microinjected into the periaqueductal gray has differential effects on 3 classes of medullary neurons
1986
Précis ofThe neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system
1982 Standout
Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry
1984 Standout
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Spinal noradrenergic terminal system mediates antinociception
1980
Microinjection of morphine into the periaqueductal gray evokes the release of serotonin from spinal cord
1979
Biphasic Modulation of Spinal Nociceptive Transmission From the Medullary Raphe Nuclei in the Rat
1997
Relative contributions of the nucleus raphe magnus and adjacent medullary reticular formation to the inhibition by stimulation in the periaqueductal gray of a spinal nociceptive reflex in the pentobarbital-anesthetized rat
1984
A subpopulation of rat dorsal root ganglion neurones is catecholaminergic
1983 Nature
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA
1991
Animal models of nociception.
2001
The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents
1986 StandoutNobel
Norepinephrine reduces excitability of single cutaneous primary afferent C-fibers in the cat spinal cord
1981
Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing
1985
Substance P as a Transmitter Candidate
1980
Nucleus locus ceruleus: new evidence of anatomical and physiological specificity
1983 Standout
The effect of systemic morphine upon diffuse noxious inhibitory controls (DNIC) in the rat: evidence for a lifting of certain descending inhibitory controls of dorsal horn convergent neurones
1981
Morphological evidence for selective modulation by serotonin of a subpopulation of dorsal horn cells which possess the neurokinin‐1 receptor
2000
Role of the Raphe Nuclei in Stimulation Producing Analgesia
1981
Opiate and opioid peptide effects on brain stem neurons: Relevance to nociception and antinociceptive mechanisms
1982
Norepinephrine and serotonin-induced antinociception are blocked by naloxone with different dosages
1994
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Effects of iontophoretically released amino acids and amines on primate spinothalamic tract cells
1984
Neurotransmitters decrease the calcium component of sensory neurone action potentials
1978 Nature
Chapter 5 Spinal dorsal horn circuitry involved in the brain stem control of nociception
1988
Bulbar raphe neurones with projections to the trigeminal nucleus caudalis and the lumbar cord in the rat: A fluorescence double-labelling study
1983
Modulation of Noxious and Non-Noxious Spinal Mechanical Transmission From the Rostral Medial Medulla in the Rat
2002
Works of B.T. Griersmith being referenced
METHYL XANTHINES, ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE AND THE SPINAL TRANSMISSION OF NOCICEPTIVE INFORMATION
1979
Inhibition of the spinal transmission of nociceptive information by supraspinal stimulation in the cat
1979
Selective reduction by noradrenaline and 5-hydroxytryptamine of nociceptive responses of cat dorsal horn neurones
1978
Methysergide and supraspinal inhibition of the spinal transmission of nociceptive information in the anaesthetized cat
1981
The effect of naloxone on the excitation of dorsal horn neurones of the cat by noxious and non-noxious cutaneous stimuli
1977
MORPHINE AND SUPRASPINAL INHIBITION OF SPINAL NEURONES: EVIDENCE THAT MORPHÌNE DECREASES TONIC DESCENDING INHIBITION IN THE ANAESTHETIZED CAT
1980
Prolonged depression of spinal transmission of nociceptive information by 5-HT administered in the substantia gelatinosa: antagonism by methysergide
1980
Lack of effect by substance P at sites in the substantia gelatinosa where met-enkephalin reduces the transmission of nociceptive impulses
1979
The need to control skin temperature when using radiant heat in tests of analgesia
1978
Supraspinal inhibition of the excitation of dorsal horn neurones by impulses in unmyelinated primary afferents: Lack of effect by strychnine and bicuculline
1981