Standout Papers
Citation Impact
Citing Papers
Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor- PSD-95 Protein Interactions
2002 Science
Patients with hippocampal amnesia cannot imagine new experiences
2007 StandoutNobel
Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors
1990
Ligands for Glutamate Receptors: Design and Therapeutic Prospects
2000
Physiological and pathophysiological roles of excitatory amino acids during central nervous system development
1990
Glutamate Antagonist Therapy Reduces Neurologic Deficits Produced by Focal Central Nervous System Ischemia
1988
Tiagabine
1998
Pre- and post-synaptic modulators of excitatory neurotransmission: comparative effects on hypoxia/hypoglycemia in cortical cultures
1994
Antigenic changes similar to those seen in neurofibrillary tangles are elicited by glutamate and Ca2+ influx in cultured hippocampal neurons
1990
Changes in extracellular amino acid neurotransmitters produced by focal cerebral ischemia
1990
Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
1989
Altered glutamatergic transmission in neurological disorders: From high extracellular glutamate to excessive synaptic efficacy
1997
Mouse Behavioral Assays Relevant to the Symptoms of Autism*
2007
Calcium-dependent glutamate cytotoxicity in a neuronal cell line
1988
A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo
1992
21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures
1990
Hippocampectomized rats are impaired in homing by path integration
1999
The neuroprotective actions of kynurenic acid and MK-801 in gerbils are synergistic and not related to hypothermia
1990
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Hypoxic neuronal injury in vitro depends on extracellular glutamine
1988
Effect of the Non‐NMDA Receptor Antagonist GYKI 52466 on the Microdialysate and Tissue Concentrations of Amino Acids Following Transient Forebrain Ischaemia
1994
Modulation of GABAergic Signaling among Interneurons by Metabotropic Glutamate Receptors
2000
Historical Overview
1988
Comparison of glutamate and gamma-aminobutyric acid uptake binding sites in frontal and temporal lobes in schizophrenia
1998
Glutamate uptake
2001 Standout
Tyrosine Phosphorylation of Microtubule‐Associated Protein Kinase After Transient Ischemia in the Gerbil Brain
1992
Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration
1997
The glutamate antagonist MK‐801 reduces focal ischemic brain damage in the rat
1988
Effect of Noncompetitive Blockade of N‐Methyl‐d‐Aspartate Receptors on the Neurochemical Sequelae of Experimental Brain Injury
1990
Biosynthesis of nitric oxide from l-arginine
1989
Changes in Extracellular Amino Acids and Spontaneous Neuronal Activity During Ischemia and Extended Reflow in the CA1 of the Rat Hippocampus
1991
Role of calcium in inactivation of calcium/calmodulin dependent protein kinase II after cerebral ischemia
1992
Excitatory amino acids and neuropsychiatrie disorders
1989
An immunohistochemical study of copper/zinc superoxide dismutase and manganese superoxide dismutase in rat hippocampus after transient cerebral ischemia
1993
Deficits of [3H]d-aspartate binding to glutamate uptake sites in striatal and accumbens tissue in patients with schizophrenia
1997
Quantitative electron microscopic immunocytochemistry of neuroactive amino acids
1989
Acidic fibroblast growth factor prevents death of hippocampal CA1 pyramidal cells following ischemia
1992
Dissociating hippocampal subregions: A double dissociation between dentate gyrus and CA1
2001
Regional and Temporal Alterations in Ca2+/Calmodulin‐Dependent Protein Kinase II and Calcineurin in the Hippocampus of Rat Brain After Transient Forebrain Ischemia
1992
Glutamate Neurotoxicity Is Independent of Calpain I Inhibition in Primary Cultures of Cerebellar Granule Cells
1991
Glutamate receptors in the mammalian central nervous system
1998
Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
1993
Increase in External Glutamate and NMDA Receptor Activation Contribute to H2O2‐Induced Neuronal Apoptosis
1999
Arachidonic Acid Metabolism in Ischemic Neuronal Damage
1989
Changes in the Activity of Protein Kinase C and the Differential Subcellular Redistribution of Its Isozymes in the Rat Striatum During and Following Transient Forebrain Ischemia
1991
Experimental ischemia induces a persistent depolarization blocked by decreased calcium and NMDA antagonists
1989
Disappearance of Rohon‐Beard neurons from the spinal cord of larval Xenopus laevis
1987
The effect of the excitatory amino acid receptor antagonist dizocilipine maleate (MK-801) on hemispheric cerebral blood flow and metabolism in dogs: modification by prior complete cerebral ischemia
1989
MK-801, an Excitatory Amino Acid Antagonist, Does Not Improve Neurologic Outcome following Cardiac Arrest in Cats
1989
Morphinans attenuate cortical neuronal injury induced by glucose deprivation in vitro
1988
Dextromethorphan protects against cerebral infarction in a rat model of hypoxia-ischemia
1988
Novel Pharmacologic Therapies in the Treatment of Experimental Traumatic Brain Injury: A Review
1993
Delayed treatment with dextromethorphan and dextrorphan reduces cerebral damage after transient focal ischemia
1988
Ethanol and neurotransmitter interactions—from molecular to integrative effects
1998
Cellular and subcellular redistribution of glutamate-, glutamine- and taurine-like immunoreactivities during forebrain ischemia: A semiquantitative electron microscopic study in rat hippocampus
1991
Regional metabolite profiles in early stages of global ischemia in the gerbil
1986
Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous d-aspartate
1993
Alzheimer's Disease: The Amyloid Cascade Hypothesis
1992 StandoutScience
Excitotoxic Amino Acids and Neuropsychiatric Disorders
1990
Amino acids as dietary excitotoxins: A contribution to understanding neurodegenerative disorders
1993
Adenosine reduces cortical neuronal injury induced by oxygen or glucose deprivation in vitro
1988
Excitotoxic injury of the neostriatum: a model for Huntington's disease
1990
Platelet‐activating factor in stroke and brain injury
1991
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Rapid potentiation of DNA binding activities of particular transcription factors with leucine-zipper motifs in discrete brain structures of the gerbil with transient forebrain ischemia
1994
Idebenone attenuates neuronal degeneration induced by intrastriatal injection of excitotoxins
1990
Alterations of a 200 kDa Neurofilament in the Rat Hippocampus after Forebrain Ischemia
1993
Biochemical Responses Mediated by N‐Methyl‐d ‐Aspartate Receptors in Rat Cortical Slices Are Differentially Sensitive to Magnesium
1992
Extracellular pH modulates N-methyl-d-aspartate receptor-mediated neurotoxicity and calcium accumulation in rat cortical cultures
1992
Structure/activity relations of N-methyl-d-aspartate receptor ligands as studied by their inhibition of [3H]d2-amino-5-phosphonopentanoic acid binding in rat brain membranes
1988
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
MK-801 protects the neonatal brain from hypoxic-ischemic damage
1987
Simultaneous blockade of non‐NMDA ionotropic receptors and NMDA receptor‐associated ionophore partially protects hippocampal slices from protein synthesis impairment due to simulated ischemia
1995
Altered Calcium Signaling and Neuronal Injury: Stroke and Alzheimer's Disease as Examplesa
1993
The Role of Glutamate Neurotoxicity in Hypoxic-Ischemic Neuronal Death
1990 Standout
Neuroprotection in Ischemia
2004
Autoradiographic characterization of putative excitatory amino acid transport sites
1990
Distribution of glutamate-like immunoreactivity in excitatory hippocampal pathways: A semiquantitative electron microscopic study in rats
1990
Glutamate and Epilepsy
2000
Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?
1989
Mild acidosis protects hippocampal neurons from injury induced by oxygen and glucose deprivation
1990
Neurons of origin of zinc-containing pathways and the distribution of zinc-containing boutons in the hippocampal region of the rat
1992
Cellular Mechanisms of Epilepsy and Potential New Treatment Strategies
1989
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Rapid desensitization determines the pharmacology of glutamate neurotoxicity
1994
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
1994 StandoutNobel
Hypoxia preferentially destroys GABAergic neurons in developing rat neocortex explants in culture
1988
Reduction of gaba and glutamate transporter messenger rnas in the severe-seizure genetically epilepsy-prone rat
1998
The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke
1992
l-Homocysteate is a potent neurotoxin on cultured cortical neurons
1987
Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia
1993
Staurosporine, a Novel Protein Kinase C Inhibitor, Prevents Postischemic Neuronal Damage in the Gerbil and Rat
1990
Localization of 70-kDa stress protein induction in gerbil brain after ischemia
1988
Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87
1993
Extracellular accumulation of glutamate in the hippocampus induced by ischemia is not calcium dependent — In vitro and in vivo evidence
1989
Kynurenate inhibition of cell excitation decreases stroke size and deficits
1987
Increases in Striatal and Hippocampal Impedance and Extracellular Levels of Amino Acids by Cardiac Arrest in Freely Moving Rats
1988
Ischemic brain injury in vitro: protective effects of NMDA receptor antagonists and calmidazolium
1990
Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex
1996
Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain
1996 StandoutNobel
Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
1998
The N-methyl-d-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils
1988
Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal ltp in the range of the θ frequency
1995 StandoutNobel
The ontogeny of excitatory amino acid receptors in rat forebrain—I.N-methyl-d-aspartate and quisqualate receptors
1990
Acidosis and ischemic brain damage
1988
Oxidative stress: Free radical production in neural degeneration
1994
A potential role for excitotoxins in the pathophysiology of spinal cord injury
1988
Glutamate receptor subunits GluR1 and GluR2/3 distribution shows reorganization in the human epileptogenic hippocampus
1998
Hypothermia Prevents the Ischemia‐Induced Translocation and Inhibition of Protein Kinase C in the Rat Striatum
1991
Alternative splicing of the NMDAR1 glutamate receptor subunit in human temporal lobe epilepsy
2000
Electron microscopic investigation of the cerebral cortex after cerebral ischemia and reperfusion in the gerbil
1992
Characterization of D‐Aspartic Acid Uptake by Rat Hippocampal Slices and Effect of Ischemic Conditions
1992
An electron microscopic, immunogold analysis of glutamate and glutamine in terminals of rat spinocerebellar fibers
1991
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h
1993
Pattern of neuronal vulnerability in the cat hippocampus after one hour of global cerebral ischemia
1990
Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists
1988
‘Ischemic tolerance’ phenomenon found in the brain
1990
Enhancement of NMDA receptor-mediated neurotoxicity in the hippocampal slice by depolarization and ischemia
1991
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
1994 StandoutNatureNobel
Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats
1991
Dextromethorphan reduces neocortical ischemic neuronal damage in vivo
1988
Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
1992
Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro
1995
The Effect of Glutamate Receptor Blockade on Anoxic Depolarization and Cortical Spreading Depression
1992
NMDA receptors - their role in long-term potentiation
1987
Pattern Separation in the Dentate Gyrus and CA3 of the Hippocampus
2007 StandoutScienceNobel
Chlorpromazine protects brain tissue in hypoxia by delaying spreading depression-mediated calcium influx
1986
Temporal profile of neuronal damage in a model of transient forebrain ischemia
1982 Standout
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Prolonged Epileptic Seizures in Primates
1973
Protection of hippocampal slices from young rats against anoxic transmission damage is due to better maintenance of ATP.
1989
Multiple actions of N-methyl-d-aspartate on cat neocortical neurons in vitro
1983
Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
2003
Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells
1986
“Epileptic” brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine
1985
Focal Cerebral Ischemia in the Cat: Pretreatment with a Competitive NMDA Receptor Antagonist, D-CPP-ene
1990
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP
2002 StandoutNobel
Extracellular Adenosine, Inosine, Hypoxanthine, and Xanthine in Relation to Tissue Nucleotides and Purines in Rat Striatum During Transient Ischemia
1987
The Glutamate Hypothesis of Schizophrenia
1997
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
Superoxide and nitric oxide cooperation in hypoxia/ reoxygenation-induced neuron injury
1993
The role of specific ions in glutamate neurotoxicity
1986
Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain.
1989
Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity
1989
Disturbance of plasmalemmal astrocytic assemblies in focal and selective cerebral ischemia
1985
Glutamate neurotoxicity in cortical cell culture
1987
Redistribution of Glutamate and Glutamine in Slices of Human Neocortex Exposed to Combined Hypoxia and Glucose Deprivation in vitro
1993
Zinc Selectively Blocks the Action of N -Methyl-D-Aspartate on Cortical Neurons
1987 Science
Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia
1998
Barbiturate Attenuation of Brain Free Fatty Acid Liberation During Global Ischemia
1981
Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells
2002 StandoutNobel
Characterization of Ca2+ signals induced in hippocampal CA1 neurones by the synaptic activation of NMDA receptors.
1993
Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain
1985
Lesions to Schaffer collaterals prevent ischemic death of CA1 pyramidal cells
1986
Low concentrations of potassium inhibit the Na-dependent [3H]glutamate binding to rat hippocampal membranes
1984
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Excitatory amino acid receptors in hippocampal neurons: Kainate fails to desensitize them
1986
Glycine potentiates the NMDA response in cultured mouse brain neurons
1987 StandoutNature
Effects of In Vivo Administration of Kainic Acid on the Extracellular Amino Acid Pool in the Rabbit Hippocampus
1983
The Medial Temporal Lobe Memory System
1991 StandoutScience
Effects of Kainic Acid on High‐Energy Metabolites in the Mouse Striatum
1982
Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy
1985 Standout
Intracellular and extracellular changes of [Ca2+] in hypoxia and ischemia in rat brain in vivo.
1990
Hippocampal Neurons Become More Vulnerable to Glutamate after Subcritical Hypoxia: An in vitro Study
1990
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Quantitative studies on some antagonists of N‐methyl D‐aspartate in slices of rat cerebral cortex
1985
Effect of the NMDA Antagonist MK-801 on Local Cerebral Blood Flow in Focal Cerebral Ischaemia in the Rat
1989
Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes
1990 Science
[1] Role of free radicals and catalytic metal ions in human disease: An overview
1990 Standout
A presynaptic locus for long-term potentiation of elementary synaptic transmission at mossy fiber synapses in culture.
1996 StandoutNobel
Treatment with an AMPA Antagonist 12 Hours following Severe Normothermic Forebrain Ischemia Prevents CA1 Neuronal Injury
1993
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
1978 Nature
Intracellular calcium concentrations during "chemical hypoxia" and excitotoxic neuronal injury
1991
Postischemic insulin reduces spatial learning deficit following transient forebrain ischemia in rats.
1989
Effects of Arachidonic Acid on Glutamate and γ‐Aminobutyric Acid Uptake in Primary Cultures of Rat Cerebral Cortical Astrocytes and Neurons
1986
Excitatory Amino Acid Release from Rat Hippocampal Slices as a Consequence of Free‐Radical Formation
1988
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Reduced fear expression after lesions of the ventral hippocampus
2002 StandoutNobel
Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury
1987 Standout
Role for Excitatory Amino Acids in Methamphetamine-Induced Nigrostriatal Dopaminergic Toxicity
1989 Science
l-Glutamate, excitatory amino acid receptors and brain function
1985
Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures
1990
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
1986 StandoutNature
Ascorbic acid in the brain
1993
Multiple Synaptic Receptors for Neuroactive Amino Acid Transmitters—New Vistas
1985
Magnesium gates glutamate-activated channels in mouse central neurones
1984 StandoutNature
Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA.
1988
Structural abnormalities in neurones.
1977
Recovery of Monkey Brain after Prolonged Ischemia. II. Protein Synthesis and Morphological Alterations
1986
Progress review: hypoglycemic brain damage.
1986
Ionic dependence of glutamate neurotoxicity
1987 Standout
Navigating from hippocampus to parietal cortex
2008 StandoutNobel
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Neural Science
2000 StandoutNobel
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
2011 StandoutNobel
Cell Damage in the Brain: A Speculative Synthesis
1981
Global brain ischemia: a reproducible monkey model.
1977
EXCITATORY AMINOACID ANTAGONISTS PROVIDE A THERAPEUTIC APPROACH TO NEUROLOGICAL DISORDERS
1985
Delayed neuronal death in the gerbil hippocampus following ischemia
1982 Standout
Synaptic Vesicular Localization and Exocytosis ofl-Aspartate in Excitatory Nerve Terminals: A Quantitative Immunogold Analysis in Rat Hippocampus
1998
Decreased Hippocampal Inhibition and a Selective Loss of Interneurons in Experimental Epilepsy
1987 Science
Graded Hypoxia-Oligemia in Rat Brain
1973
Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.
1988
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Changes in Cortical Extracellular Levels of Energy-Related Metabolites and Amino Acids following Concussive Brain Injury in Rats
1990
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists
1988
Selective chromatolysis of neurons in the gerbil brain: A possible consequence of “epileptic” activity produced by common carotid artery occlusion
1979
Focal Cerebral Ischaemia in the Cat: Treatment with the Glutamate Antagonist MK-801 after Induction of Ischaemia
1988
II. Excitotoxic models for neurodegenerative disorders
1984
Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors
1984
Fluorescent Sensors for Zn2+Based on a Fluorescein Platform: Synthesis, Properties and Intracellular Distribution
2001 StandoutNobel
Focal Cortical Seizures Cause Distant Thalamic Lesions
1982 Science
The Role of Excitatory Amino Acids and NMDA Receptors in Traumatic Brain Injury
1989 Science
Extracellular Acidity Potentiates AMPA Receptor-Mediated Cortical Neuronal Death
1998
Glutamate and the pathophysiology of hypoxic–ischemic brain damage
1986 Standout
Continuous monitoring and regulating of brain temperature in the conscious and freely moving ischemic gerbil: Effect of MK-801 on delayed neuronal death in hippocampal CA1
1997
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
Delayed Antagonism of Calpain Reduces Excitotoxicity in Cultured Neurons
1995
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.
1986 Standout
Ischemic Cell Death in Brain Neurons
1999 Standout
Enhanced Calcium Uptake by CA1 Pyramidal Cell Dendrites in the Postischemic Phase despite Subnormal Evoked Field Potentials: Excitatory Amino Acid Receptor Dependency and Relationship to Neuronal Damage
1992
Nimodipine attenuates both increase in cytosolic free calcium and histologic damage following focal cerebral ischemia and reperfusion in cats.
1989
Neurons Containing NADPH-Diaphorase Are Selectively Resistant to Quinolinate Toxicity
1986 Science
Systemic approaches to modifying quinolinic acid striatal lesions in rats
1988
Cerebral ischemia in the gerbil: Transmission electron microscopic and immunoelectron microscopic investigation
1986
Status epilepticus: The reversibility of calcium loading and acute neuronal pathological changes in the rat hippocampus
1984
Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage
1988 Standout
Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus
1986 Standout
Protective Effect of the Glutamate Antagonist, MK-801 in Focal Cerebral Ischemia in the Cat
1988
Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex.
1988
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Hypoglycemia-Induced Neuronal Damage Prevented by an N -Methyl-D-Aspartate Antagonist
1985 Science
Experimental cerebral oligemia and ischemia produced by intracranial hypertension
1975
The Influence of Arterial Hypoxia and Unilateral Carotid Artery Occlusion upon Regional Blood Flow and Metabolism in the Rat Brain
1974
CEREBRAL ENERGY METABOLISM DURING TRANSIENT ISCHEMIA AND RECOVERY IN THE GERBIL1
1977
Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D- aspartate receptor antagonist AP5
1989
Inciting Excitotoxic Cytocide Among Central Neurons
1986
Administration of Excitatory Amino Acid Antagonists via Microdialysis Attenuates the Increase in Glucose Utilization Seen following Concussive Brain Injury
1992
Protective effects of human recombinant superoxide dismutase on transient ischemic injury of CA1 neurons in gerbils.
1992
Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity
1993
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration
1986
Existence of nitric oxide synthase in rat hippocampal pyramidal cells.
1994 StandoutNobel
Postischemic Blockade of AMPA but Not NMDA Receptors Mitigates Neuronal Damage in the Rat Brain following Transient Severe Cerebral Ischemia
1992
Sustained limbic seizures induced by intraamygdaloid kainic acid in the baboon: Symptomatology and neuropathological consequences
1980
Long-Term Development of Selective Neuronal Loss and the Mechanism of Protection by 2-Amino-7-Phosphonoheptanoate in a Rat Model of Incomplete Forebrain Ischaemia
1988
Regional glucose utilization and blood flow following graded forebrain ischemia in the rat: Correlation with neuropathology
1985
Delayed Treatment with AMPA, but Not NMDA, Antagonists Reduces Neocortical Infarction
1994
Experimental cerebral oligemia and ischemia produced by intracranial hypertension
1975
Inhibition of Tyrosine Phosphorylation Prevents Delayed Neuronal Death following Cerebral Ischemia
1993
Selective neuronal death after transient forebrain ischemia in the mongolian gerbil: A silver impregnation study
1988
The physiology of excitatory amino acids in the vertebrate central nervous system
1987 Standout
Neurotoxic lesions of the dorsal hippocampus and Pavlovian fear conditioning in rats
1997
Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil
1987
Applications of quantitative measurements for assessing glutamate neurotoxicity.
1988
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Reversing cerebellar long-term depression
2003 StandoutNobel
Diffuse cerebral ischemia in the cat: III. Neuropathological sequelae of severe ischemia
1979
A Selective N-Type Calcium Channel Antagonist Reduces Extracellular Glutamate Release and Infarct Volume in Focal Cerebral Ischemia
1995
Systemic Factors and Epileptic Brain Damage
1973
Ketamine protects cultured neocortical neurons from hypoxic injury
1986
Feline Generalized Penicillin Epilepsy: Changes of Glutamic Acid and Taurine Parallel the Progressive Increase in Excitability of the Cortex
1983
Effects of dihydrokainic acid of extracellular amino acids and neuronal excitability in the in vivo rat hippocampus
1987
Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage
1990
Brain Lactic Acidosis and Ischemic Cell Damage: 2. Histopathology
1981
Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters
1985
Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase.
1996 StandoutNobel
Calcium and long‐term transmission damage following anoxia in dentate gyrus and CA1 regions of the rat hippocampal slice.
1986
Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms
2003 StandoutNobel
Cerebellar Long-Term Depression: Characterization, Signal Transduction, and Functional Roles
2001
“Epileptic” brain damage in rats induced by sustained electrical stimulation of the perforant path. I. Acute electrophysiological and light microscopic studies
1983
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain
1994
Persistent inhibition of protein synthesis precedes delayed neuronal death in postischemic gerbil hippocampus
1986
Effects of Hyperglycemia on the Time Course of Changes in Energy Metabolism and pH during Global Cerebral Ischemia and Reperfusion in Rats: Correlation of1H and31P NMR Spectroscopy with Fatty Acid and Excitatory Amino Acid Levels
1992
Ischemic Flow Threshold for Extracellular Glutamate Increase in Cat Cortex
1989
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel
Works of B.S. Meldrum being referenced
Taurine in the hippocampal formation of the Senegalese baboon, Papio papio: an immunocytochemical study with an antiserum against conjugated taurine
1985
Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs
1996
Anticonvulsant effect of reduced NMDA receptor expression in audiogenic DBA/2 mice
1996
Excitotoxicity of NMDA and kainic acid is modulated by nigrostriatal dopaminergic fibres
1989
Induction of audiogenic seizures in normal and genetically epilepsy-prone rats following focal microinjection of an excitant amino acid into reticular formation and auditory nuclei
1989
Identification and Preclinical Testing of Novel Antiepileptic Compounds
1997
Decreased sensitivity to Group III mGluR agonists in the lateral perforant path following kindling
1999
Aspartate-like and glutamate-like immunoreactivities in the inferior olive and climbing fibre system: A light microscopic and semiquantitative electron microscopic study in rat and baboon (Papio anubis)
1990
The γ-aminobutyric acid uptake inhibitor, tiagabine, is anticonvulsant in two animal models of reflex epilepsy
1995
The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats
1988
Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem
1990
Selective excitotoxic pathology in the rat hippocampus
1993
Changes in rat brain extracellular glutamate concentration during seizures induced by systemic picrotoxin or focal bicuculline injection: an in vivo dialysis study with on-line enzymatic detection
1991
EXCITOTOXIC MECHANISMS IN HYPOGLYCAEMIC HIPPOCAMPAL INJURY
1986
HYPEREXCITABILITY AND BRAIN PROTECTION
1984
Intracarotid air embolism in the baboon: Effects on cerebral blood flow and the electroencephalogram
1971
Brain damage in the rhesus monkey resulting from profound arterial hypotension. I. Its nature, distribution and general physiological correlates
1969
Does the excitatory amino acid receptor antagonist 2-APH exhibit anxiolytic activity?
1986
The Threshold and Neuropathology of Cerebral "Anoxic-Ischemic" Cell Change
1973
Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain
1984 StandoutScience
GAMMA-AMINOBUTYRIC ACID AND THE SEARCH FOR NEW ANTICONVULSANT DRUGS
1978
Excitatory amino acids and anoxic/ischaemic brain damage
1985
The role of epileptic activity in hippocampal and ‘remote’ cerebral lesions induced by kainic acid
1980
The nature and time course of the neuronal alterations resulting from oligaemia and hypoglycaemia in the brain of Macaca mulatta
1971
A comparison of the anticonvulsant potency of (±) 2-amino-5-phosphono-pentanoic acid and (±) 2-amino-7-phosphonoheptanoic acid
1983
Suppression of audiogenic seizures in DBA/2 mice by two new dipeptide NMDA receptor antagonists
1984
EPILEPTIC BRAIN DAMAGE IN ADOLESCENT BABOONS FOLLOWING SEIZURES INDUCED BY ALLYLGLYCINE
1974
ISCHAEMIC BRAIN DAMAGE: THE ROLE OF EXCITATORY ACTIVITY AND OF CALCIUM ENTRY
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Anticonvulsant Action of Excitatory Amino Acid Antagonists
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Epileptic Brain Damage: The Role of Systemic Factors That Modify Cerebral Energy Metabolism
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Evaluation of anticonvulsant drugs in DBA/2 mice with sound-induced seizures.
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Epilepsy and GABA Receptor Agonists Basic and Therapeutic Research
1986