Standout Papers
- Asymmetric epoxidation provides shortest routes to four chiral epoxy alcohols which are key intermediates in syntheses of methymycin, erythromycin, leukotriene C-1, and disparlure (1981)
- Stereoselective epoxidation of acyclic allylic alcohols. A correction of our previous work. (1979)
- Asymmetric epoxidation of homoallylic alcohols. Synthesis of (-)-.gamma.-amino-.beta.-(R)-hydroxybutyric acid (GABOB) (1984)
- Anhydrous tert-butyl hydroperoxide in toluene: the preferred reagent for applications requiring dry TBHP (1983)
Citation Impact
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1993
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1996
Catalytic Asymmetric Tandem Transformations Triggered by Conjugate Additions
2005
Construction of Quaternary Stereocenters: New Perspectives through Enantioselective Michael Reactions
2003
A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
2002 StandoutNobel
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2001 StandoutNobel
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2008 StandoutNatureNobel
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2004
Formation of Quaternary Stereocenters by Copper‐Catalyzed Michael Reactions with L ‐Valine Amides as Auxiliaries
2003
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Copper(I)-Catalyzed Synthesis of Azoles. DFT Study Predicts Unprecedented Reactivity and Intermediates
2004 StandoutNobel
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2004 Standout
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2003
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Asymmetric 1,4 addition of grignard reagents to chiral α,β-unsaturated imides in the presence of lewis acids
1996
Correlation of coordination geometry of copper atom to reactivities of organocuprate. Molecular orbital analysis of dimethylcuprate anion
1999
Asymmetric conjugate addition of diethyl zinc to enones with chiral phosphorus ligands derived from TADDOL
1998
o-DPPB-Directed Stereoselective Conjugate Addition of Organocuprates
2000
Thioether–phosphinite and diphosphinite ligands derived from d-xylose for the copper-catalyzed asymmetric 1,4-addition to 2-cyclohexenone
2005
Copper-catalysed asymmetric conjugate addition of organometallic reagents to enones using S,O-ligands with a xylofuranose backbone
2000
Catalytic Enantioselective Conjugate Addition of Dialkylzinc Compounds to Chalcones
1992
Highly Versatile Enantioselective Conjugate Addition of Grignard Reagents to α,β-Unsaturated Thioesters
2007 StandoutNobel
Tandem Asymmetric Conjugate Addition−Silylation of Enantiomerically Enriched Zinc Enolates. Synthetic Importance and Mechanistic Implications
2002
An ab initio molecular orbital study on the Lewis acidity of TMS-Cl and TMS-CN toward an α,β-unsaturated aldehyde: Are these acid-base interactions important in organocuprate 1,4-additions to enones?
1996
Catalyzed Enantioselective Alkylation of Aldehydes
1992
Copper(I) Thiolate Catalysts in Asymmetric Conjugate Addition Reactions
2004
Regio‐ und stereoselektive Synthesen mit Organokupferreagentien
1997
CuCN and Trimethylsilyl Chloride‐Catalyzed Regiospecific Grignard Reactions to CF3‐Containing Allylic Derivatives
1999
Synthesis and Characterization of Oligo(2,7‐biphenylenylene‐(E)‐vinylene)s: Conjugated Oligomers Containing Antiaromatic 12‐π Electron Units
1997
Cu-catalyzed enantioselective conjugate addition of diethylzinc to cyclic enones with chiral phosphite ligands derived from 1,2:5,6-di-O-cyclohexylidene-d-mannitol
2007
Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
2011 Standout
Pseudorotaxanes Formed Between Secondary Dialkylammonium Salts and Crown Ethers
1996 StandoutNobel
A practical asymmetric synthesis of carnitine
1988 StandoutNobel
Control of Vertex Geometry, Structure Dimensionality, Functionality, and Pore Metrics in the Reticular Synthesis of Crystalline Metal−Organic Frameworks and Polyhedra
2008 StandoutNobel
Two expedient methods for the preparation of chiral diamines
1998
New type of asymmetric double Michael reaction induced by chiral acetal
1993
Highly Enantioselective Rhodium-Catalyzed Hydrogenation with Monodentate Ligands
2000 StandoutNobel
Chiral diselenide ligands for the asymmetric copper-catalyzed conjugate addition of Grignard reagents to enones
2002
Chiral phosphorus ligands for the asymmetric conjugate addition of organocopper reagents
1993
Zeolite titanium beta as a selective catalyst in the epoxidation of bulky alkenes
1998
Recent advances in catalytic asymmetric reactions promoted by transition metal complexes
1989
Supramolecular Chemistry: Receptors, Catalysts, and Carriers
1985 StandoutScienceNobel
Chemical Routes for the Transformation of Biomass into Chemicals
2007 Standout
SN2′ Ring opening of aziridines bearing an α,β-unsaturated ester group with organocopper reagents. A new stereoselective synthetic route to (E)-alkene dipeptide isosteres
1995
Asymmetric conjugate addition of diethyl zinc to enones with chiral phosphine ligands
1997
Crystal structures of proline-derived enamines
2010 StandoutNobel
The ortho effect: copper-catalyzed highly enantioselective 1,4-conjugate addition of diethylzinc to chalcones
2006
Enantioselective conjugate addition of diethylzinc to cyclic enones with chiral aryl diphosphite-copper catalysts
1999
Enantioselective Conjugate Addition of Dialkylzinc Reagents to Cyclic and Acyclic Enones Catalyzed by Chiral Copper Complexes of New Phosphorus Amidites
1996 StandoutNobel
Regio‐ and Stereoselective Syntheses with Organocopper Reagents
1997
Diastereomeric phosphite–pyridine ligands for enantioselective 1,4-conjugate additions
2005
1,4-Addition of Diorganozincs to α,β-Unsaturated Ketones Catalyzed by a Copper(I)-Sulfonamide Combined System
2000 StandoutNobel
Catalytic Enantioselective Conjugate Addition with Grignard Reagents
2007 StandoutNobel
Asymmetric Induction in the Arenethiolatocopper(I)-Catalyzed Substitution Reaction of Grignard Reagents with Allylic Substrates
2000
(+)-Camphor-derived tri- and tetradentate amino alcohols; synthesis and application as ligands in the nickel catalyzed enantioselective conjugate addition of diethylzinc
1997 StandoutNobel
Stereoselective 1,4-addition of Grignard reagents to chiral γ-alkoxy-α,β-unsaturated ketones
1997
Synthesis and Application of Chiral Phosphorus Ligands Derived from TADDOL for the Asymmetric Conjugate Addition of Diethyl Zinc to Enones
2000
The Atom Economy—A Search for Synthetic Efficiency
1991 StandoutScience
On the way to chiral copper(I) arenethiolate catalysts for the enantioselective conjugate addition of methyl lithium and methyl magnesium iodide to benzylideneacetone
1991
Kinetic Implications of Nonlinear Effects in Asymmetric Synthesis
1998
Cu(I) Tol-BINAP-Catalyzed Enantioselective Michael Reactions of Grignard Reagents and Unsaturated Esters
2006
Enantioselective Cu-catalyzed 1,4-addition of Me3Al to a 4,4-disubstituted cyclohexa-2,5-dienone: Novel effect of trialkylsilylOTf on enantioselectivity
1996
Phosphoramidites: Marvellous Ligands in Catalytic Asymmetric Conjugate Addition
2000 StandoutNobel
Enantioselective conjugate addition of diethylzinc to chalcones catalysed by chiral Ni(II) aminoalcohol complexes
1994 StandoutNobel
Conjugate Additions of Nitroalkanes to Electron-Poor Alkenes: Recent Results
2005
ChemInform Abstract: Conjugate Addition of Organometallic Reagents
2000
Diastereoselection in the conjugate additions of organocopper reagents to N-enoyloxazolidinones
1998
Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis
2008 StandoutNobel
Enantioselective conjugate addition of diethylzinc to cyclic enones catalyzed by chiral copper complexes containing a new phosphorus ligand with an H8-binaphthoxy moiety
1998
Copper-catalysed asymmetric conjugate addition of organometallic reagents to linear enones using thiourethane ligands
1999
Arenethiolatocopper(I) complexes as homogeneous catalysts for Michael addition reactions
1994
Rhodium-catalyzed asymmetric 1,4-addition of arylboron reagents to α,β-unsaturated esters
1999
New chiral amino-phosphoramidite and bisphosphoramidite ligands derived from (R,R)-1,2-diaminocyclohexane: application in Cu-catalyzed asymmetric conjugate addition of diethylzinc to 2-cyclohexenone
2003
Enantioselective conjugate additions of organolithiums to BHA enoates mediated by A chiral ligand
1997
Sugar–phosphite–oxazoline and phosphite–phosphoroamidite ligand libraries for Cu-catalyzed asymmetric 1,4-addition reactions
2007
New chiral ligands for the asymmetric copper catalyzed conjugate addition of Grignard reagents to enones
1997
It's on lithium! an answer to the recent communication which asked the question: ‘if the cyano ligand is not on copper, then where is it?’
1996
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Artificial Molecular Machines
2000 StandoutNobel
Click-Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen
2001 StandoutNobel
Highly Enantioselective Catalytic Conjugate Additions to Cyclohexadienones
1999 StandoutNobel
Construction of Optically Active CF3-Containing Quaternary Carbon Centers via Stereospecific SN2‘ Reaction
2004
Highly Enantioselective Copper-Catalyzed Conjugate Addition of Diethylzinc to Enones Using Chiral Spiro Phosphoramidites as Ligands
2003
Chemical studies on slow reacting substances/leukotrienes
1982 StandoutNobel
Asymmetric Michael addition of nitroalkanes to prochiral acceptors catalyzed by proline rubidium salts
1997
Enantioselective Conjugate Additions
2000
Molecular Receptors. Structural Effects and Substrate Recognition in Binding of Organic and Biogenic Ammonium Ions by Chiral Polyfunctional Macrocyclic Polyethers Bearing Amino‐Acid and Other Side‐Chains
1982
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis.
1983 StandoutNobel
Catalytic Enantioselective Conjugate Addition with Grignard Reagents
2006 StandoutNobel
On the Mechanism of the Copper-Catalyzed Enantioselective 1,4-Addition of Grignard Reagents to α,β-Unsaturated Carbonyl Compounds
2006 StandoutNobel
Enantioselective 1,4‐Addition of Aliphatic Grignard Reagents to Enones Catalyzed by Readily Available Copper(I) thiolates derived from TADDOL. Preliminary communication
1997
Catalytic asymmetric conjugate addition of grignard reagents mediated by copper(I)-chiral bidentate phosphine complex
1995
Enantioselective Conjugate Addition of Diethylzinc to Chalcones Using NiCl2-Chiral β-Diamine Complex as Catalyst
1994
The genesis of a new range of interlocked molecules
1996 StandoutNobel
Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates
2018 StandoutScienceNobel
Catalytic Asymmetric Conjugate Addition and Allylic Alkylation with Grignard Reagents
2008 StandoutNobel
Selectivity: A Key to Synthetic Efficiency
1983 Science
Cu-catalysed asymmetric 1,4-addition of Me3Al to nitroalkenes. Synthesis of (+)-ibuprofen
2005
Copper(I) phosphoramidite catalyzed asymmetric conjugate addition of dialkylzinc reagents of α,β-unsaturated nitroacetates; an enantioselective route to β-aryl-nitroalkanes
1999 StandoutNobel
Diastereoselective conjugate addition of Grignard reagents to a homochiral fumaramide derived from Oppolzer’s sultam
2004
Diastereoselective Synthesis of Thieno[3′,2′:4,5]cyclopenta[1,2‐d][1,3]oxazolines − New Ligands for the Copper‐Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Enones
2004
A Study of the Complexation of Bis(m-Phenylene) Crown Ethers and Secondary Ammonium Ions
1998
Asymmetric conjugate addition to alkylidene malonates
2001
Enantioselective Catalytic Conjugate Addition of Dialkylzinc Reagents using Copper–Phosphoramidite Complexes; Ligand Variation and Non-linear Effects
2000 StandoutNobel
Biphenol-based ligands for Cu-catalyzed asymmetric conjugate addition
2004
Asymmetric addition of aryllithiums to naphthalene bha-esters catalyzed by a chiral ligand
1993
Enantioselective Cu-catalyzed 1,4-addition of Me3Al to a 4,4-disubstituted cyclohexa-2,5-dienone
1996
Catalytic enantioselective conjugate addition of Grignard reagents to cyclic α,β-unsaturated carbonyl compounds
1999
Recent advances in enantioselective copper-catalyzed 1,4-addition
2009 StandoutNobel
An external chiral amidophosphine ligand for asymmetric conjugate addition of organocopper
1998
Correlation of Reactivities of Organocuprate(I) and Zincate(II) with d-Orbital Energies of Ate Complexes
2000
Asymmetric conjugate addition of organomagnesium cuprates controlled by a stoichiometric amount of chiral phosphine
1995
Highly enantioselective copper-catalyzed 1,4-conjugate addition of diethylzinc to cyclic enones and α,β-unsaturated lactones
2004
Mechanism and Stereoselectivity of Asymmetric Hydrogenation
1982 Science
Recent developments in the stereoselective synthesis of α-aminoacids
1994
A study of conjugate addition to a γ,δ-dioxolanyl-α,β-unsaturated ester
2001
Asymmetrische Micheal‐Additionen. Praktisch vollständigdiastereo‐ und enantioselektive Alkylierungen des Enamins aus Cyclohexanon und Prolinylmethyläther.durch ω‐Nitrostyrole zu u‐2‐(l′‐Aryl‐2′‐nitroäthyl)cyclohexanonen
1982
Remarkable asymmetric induction from remote stereocenters in conjugate addition chemistry for the synthesis of alkyl‐branched α, ω‐diaminoazelates
2001
Enantioselective copper-catalyzed conjugate addition of diethylzinc to enones using new chiral P,N ligands composed of (S)-2-alkyl-2-aminoethylphosphines and α-substituted pyridines
2000
Copper-catalyzed asymmetric conjugate addition of Grignard reagents to cyclic enones
2004 StandoutNobel
Asymmetric conjugate addition of metal alkyl reagents catalyzed by copper complexes with BINPO: a hemilabile P,O-heterobidentate axially chiral ligand
2005
Enantioselective Copper‐Catalyzed 1,4‐Addition of Grignard Reagents to α,β‐Unsaturated Carbonyl Compounds
1993
Chiral Metal Complexes as Discriminating Molecular Catalysts
1990 StandoutScienceNobel
Asymmetric 1,4‐Addition of Diethylzinc to Cyclic Enones Catalyzed by Cu(I)‐Chiral Sulfonamide‐Thiophosphoramide Ligands and Lithium Salts
2005
A new chiral 2-sulfonylamino-2′-phosphino-1,1′-binaphthyl ligand for highly enantioselective copper-catalyzed conjugate addition of diethylzinc to benzylideneacetones
2004
Catalytic enantioselective conjugate addition of diethylzinc using NiII-DAIB complexes.
1992 StandoutNobel
Homochiral and Heterochiral Dimers of the Methylzinc Alkoxide Formed from Dimethylzinc and Enantiomeric 3‐exo‐(Dimethylamino)isoborneol—Origin of the Distinct Differences in Solution‐Phase Behavior and Crystal Structures
1996 StandoutNobel
Chiral amplification and the catalytic process in the enantioselective conjugate addition of chiral alkoxydimethylcuprate to (E)-cyclopentadec-2-en-l-one
1993
Biphenol-Based Phosphoramidite Ligands for the Enantioselective Copper-Catalyzed Conjugate Addition of Diethylzinc
2004
Asymmetric Michael addition promoted by (R,R)-trans-1,2-diaminocyclohexane in ionic liquids
2005
Asymmetric 1,4-addition of diethylzinc to α,β-unsaturated enones catalyzed by chiral imino-thiophosphoramide ligands and copper(I)
2003
Asymmetric conjugate addition of diethyl zinc to enones with tartrate chiral phosphite ligands
1997
Copper-catalyzed conjugate addition of trialkylaluminium to α,β-unsaturated carbonyl compounds
1995
Asymmetric Enamine Catalysis
2007 StandoutNobel
Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry
2008 StandoutNobel
Ruthenium catalysed oxidation without CCl4 of oleic acid, other monoenic fatty acids and alkenes
2005
Wherefore Art Thou Copper? Structures and Reaction Mechanisms of Organocuprate Clusters in Organic Chemistry
2000
Crown Ethers: Sensors for Ions and Molecular Scaffolds for Materials and Biological Models
2004 Standout
Bicyclic O,P Ligands for Catalytic Asymmetric 1,4‐Addition to α,β‐Unsaturated Ketones
2004
Catalytic asymmetric Michael addition of nitroalkane to enone and enal
1994
Copper catalysed 1,4-addition of organozinc reagents to α,β-unsaturated carbonyl compounds: a mechanistic investigation
2004
Selectivity Guidelines and a Reductive Elimination-Based Model for Predicting the Stereochemical Course of Conjugate Addition Reactions of Organocuprates to γ-Alkoxy-α,β-enoates
2006
Highly enantioselective copper-catalyzed conjugate addition of diethylzinc to cyclic enones with spirocyclic phosphoramidite ligands
2005
Chiral aminophosphine–oxazoline auxiliaries applied to copper-catalysed enantioselective 1,4-additions to enones
2004
Enantioselective conjugate addition of diethylzinc to enones catalyzed by a copper complex of chiral aryl diphosphite
1999
Chiral mercaptoaryl-oxazolines as ligands in enantioselective copper-catalyzed 1,4-additions of Grignard reagents to enones
1994
Works of Bryant E. Rossiter being referenced
The Structure of "R2Cu(CN)Li2" Lithium Cuprates: Lower-Order Aggregates of Gilman Reagents and Organo Lithium Compounds
1994
Cyclic Polyether-Protonated Organic Amine Binding: Significance in Enzymatic and Ion Transport Processes
1978 Science
Enantioselective conjugate addition with chiral amidocuprates
1990
New Copper Chemistry. 25. Effect of TMSCl on the Conjugate Addition of Organocuprates to .alpha.-Enones: A New Mechanism
1995
Asymmetric epoxidation of homoallylic alcohols. Synthesis of (-)-.gamma.-amino-.beta.-(R)-hydroxybutyric acid (GABOB)
1984 StandoutNobel
Enantioselective conjugate addition to cyclic enones with scalemic lithium organo(amido)cuprates, Part IV. Relationship between ligand structure and enantioselectivity
1993
Asymmetric conjugate addition
1992
Thermodynamics of formation of 18-crown-6 complexes with arenediazonium and anilinium salts in methanol at 25 °C
1978
A calorimetric titration study of the reaction of several organic ammonium cations with 18-crown-6 in methanol
1979
Asymmetric epoxidation provides shortest routes to four chiral epoxy alcohols which are key intermediates in syntheses of methymycin, erythromycin, leukotriene C-1, and disparlure
1981 StandoutNobel
Enantioselective conjugate addition to cyclic enones with (S)-mapp-cuprates.
1991
Enantioselective conjugate addition, part V. Synthesis and testing of scalemic tetraamines as chiral cuprate ligands.
1994
Influence of the Aromatic Substituent on the Reactivity of (R)-N-Methyl-1-phenyl-2-(1-piperidinyl)ethanamine Cuprates in Enantioselective Conjugate Addition
1995
Enantioselective conjugate addition with chiral amidocuprates, part III. Studies on the synthetic optimization of MAPP-cuprates.
1992