Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Phenotypic and functional features of human Th17 cells
2007 Standout
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
Notch regulates IL-10 production by T helper 1 cells
2008
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category
2008
Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
2003 Standout
Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells
2009
IFN-γ-induced Th1-Treg polarization in inflamed brains limits exacerbation of experimental autoimmune encephalomyelitis
2024
IL-21 Mediates Suppressive Effects via Its Induction of IL-10
2009
IL-22 Is Expressed by Th17 Cells in an IL-23-Dependent Fashion, but Not Required for the Development of Autoimmune Encephalomyelitis
2007
Cutting Edge: IL-27 Is a Potent Inducer of IL-10 but Not FoxP3 in Murine T Cells
2008
IL-10: The Master Regulator of Immunity to Infection
2008 Standout
IL-27 Activates Human Monocytes via STAT1 and Suppresses IL-10 Production but the Inflammatory Functions of IL-27 Are Abrogated by TLRs and p38
2008
IL-23 Is Critical in the Induction but Not in the Effector Phase of Experimental Autoimmune Encephalomyelitis
2007
IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation
2016
Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation
2014
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction
2015
Human Endogenous Retroviruses in Neurological Diseases
2018
The regulation of IL-10 production by immune cells
2010 Standout
Inflammation and Alzheimer's disease
2000 Standout
Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study
2008
Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
2006
Immunological update on multiple sclerosis
2001
National Institutes of Health Center for Human Immunology Conference, September 2009
2010
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Treatment of progressive multiple sclerosis: what works, what does not, and what is needed
2015
From classic to spontaneous and humanized models of multiple sclerosis: Impact on understanding pathogenesis and drug development
2014
A New Twist in TCR Diversity Revealed by a Forbidden αβ TCR
2007 StandoutNobel
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
2005 Standout
The IL-12 Family of Heterodimeric Cytokines
2003
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
2011
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Antiviral immune responses: triggers of or triggered by autoimmunity?
2009
Current Views on the Roles of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis
2010
RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
2011
Tolerance and Autoimmunity
2001
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis
2007
Psoriasis pathogenesis and the development of novel targeted immune therapies
2017
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
2006
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
Type I Interferons Induce T Regulatory 1 Responses and Restrict Humoral Immunity during Experimental Malaria
2016
Immunopathology of multiple sclerosis
2015 Standout
Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties
2006
IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection
2008
A de Novo Designed Template for Generating Conformation-specific Antibodies That Recognize α-Helices in Proteins
2002
Antigen-specific therapeutic approaches for autoimmunity
2019
Immunity, Inflammation, and Cancer
2010 Standout
Recognition of Conserved Amino Acid Motifs of Common Viruses and Its Role in Autoimmunity
2005 StandoutNobel
Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system
2006
The PD‐1 pathway in tolerance and autoimmunity
2010 Standout
A virus-induced molecular mimicry model of multiple sclerosis
2001
Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis
2007
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
2016 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation
2014
Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation
2018
Unbiased identification of target antigens of CD8+ T cells with combinatorial libraries coding for short peptides
2012
Diversity in the contribution of interleukin‐10 to T‐cell‐mediated immune regulation
2008
Chapter 5 Emergence of the Th17 Pathway and Its Role in Host Defense
2008
Tuning Microenvironments: Induction of Regulatory T Cells by Dendritic Cells
2008
Modulation of experimental autoimmune encephalomyelitis by endogenous Annexin A1
2009
Interleukin-10 Production by Th1 Cells Requires Interleukin-12-Induced STAT4 Transcription Factor and ERK MAP Kinase Activation by High Antigen Dose
2009
Multiple sclerosis
2002 Standout
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease
2010
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
A virus-induced molecular mimicry model of multiple sclerosis
2001
IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis
2006 Standout
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
2005 Standout
INFLAMMATION AND ALZHEIMERS DISEASE
2000
Contrasting roles for all-trans retinoic acid in TGF-β–mediated induction of Foxp3 and Il10 genes in developing regulatory T cells
2009
Treg functional stability and its responsiveness to the microenvironment
2014
IL-17 and Th17 Cells
2009 Standout
IL-17 Family Cytokines and the Expanding Diversity of Effector T Cell Lineages
2007 Standout
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
IMMUNOLOGY OF MULTIPLE SCLEROSIS
2005 Standout
Therapeutic Induction of Regulatory, Cytotoxic CD8+ T Cells in Multiple Sclerosis
2006
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Identification of MHC Class II-Restricted Peptide Ligands, Including a Glutamic Acid Decarboxylase 65 Sequence, that Stimulate Diabetogenic T Cells from Transgenic BDC2.5 Nonobese Diabetic Mice
2001
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
IL-27 Regulates IL-10 and IL-17 from CD4+ Cells in Nonhealing Leishmania major Infection
2009
IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4+ T Cells
2009
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Antigen-Specific Tolerance by Autologous Myelin Peptide–Coupled Cells: A Phase 1 Trial in Multiple Sclerosis
2013
Expansion and Functional Relevance of High-Avidity Myelin-Specific CD4+ T Cells in Multiple Sclerosis
2004
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
2008
Randomized phase 1b trial of MOR103, a human antibody to GM-CSF, in multiple sclerosis
2015
ERK1−/− Mice Exhibit Th1 Cell Polarization and Increased Susceptibility to Experimental Autoimmune Encephalomyelitis
2006
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy
2015
PD-1 and Its Ligands in Tolerance and Immunity
2008 Standout
Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease
2011 Standout
Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions
2015 StandoutNobel
Works of Bruno Gran being referenced
Cutting Edge: TLR3 Stimulation Suppresses Experimental Autoimmune Encephalomyelitis by Inducing Endogenous IFN-β
2006
Suppressive Effect of IL-27 on Encephalitogenic Th17 Cells and the Effector Phase of Experimental Autoimmune Encephalomyelitis
2007
Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
2011
The association between human endogenous retroviruses and multiple sclerosis: A systematic review and meta-analysis
2017
The PD-1/PD-L pathway is up-regulated during IL-12-induced suppression of EAE mediated by IFN-gamma
2007
Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia
2006
Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease
1999
CNS-specific Therapy for Ongoing EAE by Silencing IL-17 Pathway in Astrocytes
2012
Early administration of IL-12 suppresses EAE through induction of interferon-γ
2004
Lessons from studies of antigen-specific T cell responses in Multiple Sclerosis
2000
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
2000
Exploring immunological specificity using synthetic peptide combinatorial libraries
1999
Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia
2003
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27–stimulated T cells
2007
IL-27 subunits and its receptor (WSX-1) mRNAs are markedly up-regulated in inflammatory cells in the CNS during experimental autoimmune encephalomyelitis
2005
Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders
2002
Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells
2014
Fatigue in multiple sclerosis — A brief review
2012
Molecular mimicry and multiple sclerosis: Degenerate T-cell recognition and the induction of autoimmunity
1999
Cutting Edge: Predictable TCR Antigen Recognition Based on Peptide Scans Leads to the Identification of Agonist Ligands with No Sequence Homology
1998
TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function
2011
Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology.
1998
Role of IL-12 Receptor β1 in Regulation of T Cell Response by APC in Experimental Autoimmune Encephalomyelitis
2003
Induction of Experimental Autoimmune Encephalomyelitis in IL-12 Receptor-β2-Deficient Mice: IL-12 Responsiveness Is Not Required in the Pathogenesis of Inflammatory Demyelination in the Central Nervous System
2003
Mechanisms of immunomodulation by glatiramer acetate
2000
IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination
2002
Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency
2000
Transforming growth factor‐β1 inhibits the proliferation of rat astrocytes induced by serum and growth factors
1995
Combinatorial Peptide Libraries and Biometric Score Matrices Permit the Quantitative Analysis of Specific and Degenerate Interactions Between Clonotypic TCR and MHC Peptide Ligands
2001
Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS
2001