Citation Impact
Citing Papers
Evolution of the Cancer Stem Cell Model
2014 Standout
Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1)
2016
The DNA-damage response in human biology and disease
2009 StandoutNature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Engineering cellular microenvironments to improve cell-based drug testing
2002
The third dimension bridges the gap between cell culture and live tissue
2007 Standout
Selective inhibition of bleomycin-induced G2 cell cycle checkpoint by simaomicin α
2004 StandoutNobel
Mechanism Targeted Discovery of Antitumor Marine Natural Products
2004
Isolation, identification, and biological evaluation of HIF-1-modulating compounds from Brazilian green propolis
2011 StandoutNobel
Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
2009 Standout
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
2012 Standout
Natural products: A continuing source of novel drug leads
2013 Standout
Marine natural products
1990 Standout
Drug development from marine natural products
2008 Standout
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Marine pharmacology in 2000: Antitumor and cytotoxic compounds
2003
Anticancer drugs from nature—natural products as a unique source of new microtubule-stabilizing agents
2007
Cancer stem cells revisited
2017 Standout
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
Trans‐activation of the DNA‐damage signalling protein kinase Chk2 by T‐loop exchange
2006
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Scalarane-based metabolites isolated from the antimitotic extract of the marine spongeHyrtios erectus
2008
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Malignant Gliomas in Adults
2008 Standout
Small Molecule Modulation of the Human Chromatid Decatenation Checkpoint
2003
Marine pharmacology in 2001–2002: Marine compounds with anthelmintic, antibacterial, anticoagulant, antidiabetic, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems and other miscellaneous mechanisms of action
2005
Role of the gut microbiota in nutrition and health
2018 Standout
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
Diterpenes from gorgonian corals
2009
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
2011 Standout
Cell-cycle dysregulation and anticancer therapy
2003
Survey of 2,11-cyclized cembranoids from Caribbean sources
2009
Reactive oxygen species in cancer
2010 Standout
Biomedicinals from the phytosymbionts of marine invertebrates: A molecular approach
2007
The cancer stem cell: premises, promises and challenges
2011 Standout
Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint
2006
Primary brain tumours in adults
2012 Standout
Targeting DNA topoisomerase II in cancer chemotherapy
2009 Standout
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial
2010 Standout
Identification of a buried pocket for potent and selective inhibition of Chk1: Prediction and verification
2005
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
Sespendole, a New Inhibitor of Lipid Droplet Synthesis in Macrophages, Produced by Pseudobotrytis terrestris FKA-25
2006 StandoutNobel
Total Synthesis of Spirastrellolide F Methyl Ester—Part 1: Strategic Considerations and Revised Approach to the Southern Hemisphere
2009
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
ROS and the DNA damage response in cancer
2018 Standout
Pathogenic fungus harbours endosymbiotic bacteria for toxin production
2005 Nature
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
2012 Standout
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Topoisomerase I inhibitors: camptothecins and beyond
2006 Standout
Boromycin Abrogates Bleomycin-induced G2 Checkpoint
2004 StandoutNobel
Update on tubulin-binding agents
2005
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Marine Natural Products and Related Compounds in Clinical and Advanced Preclinical Trials
2004
UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
2002 Nobel
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
The Hidden World within Plants: Ecological and Evolutionary Considerations for Defining Functioning of Microbial Endophytes
2015 Standout
Sponge-Associated Microorganisms: Evolution, Ecology, and Biotechnological Potential
2007 Standout
Metabolomics Investigation To Shed Light on Cheese as a Possible Piece in the French Paradox Puzzle
2015
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
2017 Standout
Terpenoids from Marine Organisms: Unique Structures and their Pharmacological Potential
2006
Climate impact of beef: an analysis considering multiple time scales and production methods without use of global warming potentials
2015
Enzyme Inhibitors from Marine Invertebrates
2007
Fungal Malformins Inhibit Bleomycin-Induced G2 Checkpoint in Jurkat Cells
2007 StandoutNobel
Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors
2007
Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products
2013 Standout
(Z)-Sarcodictyin A, a New Highly Cytotoxic Diterpenoid from the Soft Coral Bellonella albiflora
2003
Marine natural products
2018 Standout
Turnagainolides A and B, Cyclic Depsipeptides Produced in Culture by a Bacillus sp.: Isolation, Structure Elucidation, and Synthesis
2011
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Meat consumption, health, and the environment
2018 StandoutScience
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Briarane, Erythrane, and Aquariane Diterpenoids from the Caribbean Gorgonian Erythropodium caribaeorum
2003
Synthesis of granulatimide analogues bearing a maleimide instead of an imidazole heterocycle
2003
Synthetic Analogues of the Microtubule-Stabilizing Sponge Alkaloid Ceratamine A Are More Active than the Natural Product
2010
Cytotoxic effects of nanoparticles assessed in vitro and in vivo.
2007
Spirastrellolide A, An Antimitotic Macrolide Isolated from the Caribbean Marine Sponge Spirastrella coccinea
2003
Synthetic Approaches to the Microtubule-Stabilizing Sponge Alkaloid Ceratamine A and Desbromo Analogues
2009
OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins
2015 Standout
A Medicinal Chemist’s Guide to Molecular Interactions
2010 Standout
3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs
2014 Standout
Modern Natural Products Drug Discovery and Its Relevance to Biodiversity Conservation
2010
Antineoplastic agents from natural sources: achievements and future directions
2000
Works of Bruno Cinel being referenced
Fatty acid profiles of North American beef produced using organic and natural systems.
2014
Inhibition of the G2 DNA Damage Checkpoint and of Protein Kinases Chk1 and Chk2 by the Marine Sponge Alkaloid Debromohymenialdisine
2001
Rapid Determination of Total Conjugated Linoleic Acid Content in Select Canadian Cheeses by1H NMR Spectroscopy
2013
Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts.
2000
Antimitotic Diterpenes from Erythropodium caribaeorum Test Pharmacophore Models for Microtubule Stabilization
2000