Citation Impact
Citing Papers
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines
2007 StandoutNobel
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
NSAID use and dementia risk in the Cardiovascular Health Study*
2007
Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
2010 StandoutScience
Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ
2006
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
2013
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
2009 StandoutScience
Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo
2005 StandoutScience
Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
2012
Interactions between APP secretases and inflammatory mediators
2008
Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice
2005
The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
2014
Anti-Inflammatory Actions of Neuroprotectin D1/Protectin D1 and Its Natural Stereoisomers: Assignments of Dihydroxy-Containing Docosatrienes
2006
Microglia as a Potential Bridge between the Amyloid β‐Peptide and Tau
2004
Transgenic mouse models of Alzheimer's disease: How useful have they been for therapeutic development?
2004
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
A decade of modeling Alzheimer's disease in transgenic mice
2006
Inflammation and Alzheimer's disease
2000 Standout
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease
2005
Inflammatory processes in Alzheimer's disease
2007
Evidence That Nonsteroidal Anti-inflammatory Drugs Decrease Amyloid β42 Production by Direct Modulation of γ-Secretase Activity
2003
3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors Attenuate β-Amyloid-Induced Microglial Inflammatory Responses
2005
Is there a future for vaccination as a treatment for Alzheimer's disease?
2003
Systemic infections and inflammation affect chronic neurodegeneration
2007
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
2007
Microglial senescence: does the brain's immune system have an expiration date?
2006
Aβ Oligomers – a decade of discovery
2007 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice
2002
Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice
2001
Calpain and caspase: can you tell the difference?
2000 Standout
Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway
2007
Inflammation in Neurodegenerative Disease—A Double-Edged Sword
2002
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
Foundation models for generalist medical artificial intelligence
2023 StandoutNature
Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer’s disease
2017
NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies
2006
Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease
2003
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein
2002
PGH2‐derived levuglandin adducts increase the neurotoxicity of amyloid β1–42
2006
Glucocorticoids Increase Amyloid-β and Tau Pathology in a Mouse Model of Alzheimer’s Disease
2006
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
2001 Nature
The Non-cyclooxygenase Targets of Non-steroidal Anti-inflammatory Drugs, Lipoxygenases, Peroxisome Proliferator-activated Receptor, Inhibitor of κB Kinase, and NFκB, Do Not Reduce Amyloid β42 Production
2003
β-Secretase-Cleaved Amyloid Precursor Protein Accumulates at Actin Inclusions Induced in Neurons by Stress or Amyloid β: A Feedforward Mechanism for Alzheimer's Disease
2005
IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior
2015
Morphologic and biochemical hallmarks of apoptosis
2000
Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology
2001
The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction
1999
Modulation of Nuclear Factor-κB Activity by Indomethacin Influences Aβ Levels but Not Aβ Precursor Protein Metabolism in a Model of Alzheimer's Disease
2004
Monoclonal antibodies that target pathological assemblies of Aβ
2006
The Role of Insulin, Insulin Growth Factor, and Insulin‐Degrading Enzyme in Brain Aging and Alzheimer′s Disease
2005
The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research
2009
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Microglial Activation is Required for Aβ Clearance After Intracranial Injection of Lipopolysaccharide in APP Transgenic Mice
2007
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Targeting soluble Aβ peptide with Tramiprosate for the treatment of brain amyloidosis
2006
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice
2006
Making and repairing the mammalian brain—signaling toward neurogenesis and gliogenesis
2003
Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo
2004 Standout
Role of DNA Methylation in the Regulation of Cell Function: Autoimmunity, Aging and Cancer
2002
ApoE genotype accounts for the vast majority of AD risk and AD pathology
2004
The Role of Insulin Resistance in the Pathogenesis of Alzheimer??s Disease
2003
Neurodegeneration and Inflammation
2008
Dietary Docosahexaenoic Acid and Docosapentaenoic Acid Ameliorate Amyloid-β and Tau Pathology via a Mechanism Involving Presenilin 1 Levels
2007
Dissection of Amyloid-β Precursor Protein-dependent Transcriptional Transactivation
2004 StandoutNobel
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
2008
Chronic nicotine treatment reduces β‐amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw)
2002
DNA Methylation and Its Basic Function
2012 Standout
Sustained hippocampal IL-1β overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology
2007
Deletion of the Prostaglandin E2EP2 Receptor Reduces Oxidative Damage and Amyloid Burden in a Model of Alzheimer's Disease
2005
DNA Methylation Is a Critical Cell-Intrinsic Determinant of Astrocyte Differentiation in the Fetal Brain
2001
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
2001
Alzheimer's disease
2006 Standout
Absence of C1q Leads to Less Neuropathology in Transgenic Mouse Models of Alzheimer's Disease
2004
A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor
2000
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
The Role of Apolipoprotein E in Alzheimer's Disease
2009
Microglia and Alzheimer's disease pathogenesis
2004
Cyclooxygenase and Alzheimer's disease: implications for preventive initiatives to slow the progression of clinical dementia
2001
Alzheimer's Disease
2010 Standout
Does my mouse have Alzheimer's disease?
2002
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
2005
Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity
2011
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
2010
Tannic Acid Is a Natural β-Secretase Inhibitor That Prevents Cognitive Impairment and Mitigates Alzheimer-like Pathology in Transgenic Mice
2012
Lack of Specific Amyloid-β(1-42) Suppression by Nonsteroidal Anti-Inflammatory Drugs in Young, Plaque-Free Tg2576 Mice and in Guinea Pig Neuronal Cultures
2004
The role of senescent cells in ageing
2014 StandoutNature
Sulindac Sulfide Is a Noncompetitive γ-Secretase Inhibitor That Preferentially Reduces Aβ42 Generation
2003
Microglial EP2 as a New Target to Increase Amyloid β Phagocytosis and Decrease Amyloid β-Induced Damage to Neurons
2006
The Hallmarks of Aging
2013 Standout
Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1–42 levels in APPV717I transgenic mice
2005
Lipopolysaccharide-Induced Inflammation Exacerbates Tau Pathology by a Cyclin-Dependent Kinase 5-Mediated Pathway in a Transgenic Model of Alzheimer's Disease
2005
Dynamic Complexity of the Microglial Activation Response in Transgenic Models of Amyloid Deposition: Implications for Alzheimer Therapeutics
2005
Intracellular amyloid-β in Alzheimer's disease
2007 Standout
The role of microglia in amyloid clearance from the AD brain
2010
Resveratrol Supplementation Does Not Improve Metabolic Function in Nonobese Women with Normal Glucose Tolerance
2012
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Genetic risk profiles for Alzheimer's disease: Integration of APOE genotype and variants that up-regulate inflammation
2006
Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo
2004
Intraneuronal β-Amyloid Expression Downregulates the Akt Survival Pathway and Blunts the Stress Response
2005
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Frailty in elderly people
2013 Standout
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Insulin Resistance and Alzheimer’s Disease: Bioenergetic Linkages
2017
Overexpression of Monocyte Chemotactic Protein-1/CCL2 in β-Amyloid Precursor Protein Transgenic Mice Show Accelerated Diffuse β-Amyloid Deposition
2005
Peripheral Treatment with Enoxaparin, a Low Molecular Weight Heparin, Reduces Plaques and β-Amyloid Accumulation in a Mouse Model of Alzheimer's Disease
2004
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
2007
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo
2003
Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties
2010 Standout
The Aging Brain
2008
Protective effects of NSAIDs on the development of Alzheimer disease
2008
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
One-Step Assembly of Coordination Complexes for Versatile Film and Particle Engineering
2013 StandoutScience
Extending the Nested Model for User-Centric XAI: A Design Study on GNN-based Drug Repurposing
2022
INFLAMMATION AND ALZHEIMERS DISEASE
2000
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
Common Pathological Processes and Transcriptional Pathways in Alzheimer's Disease and Type 2 Diabetes
2009
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Mechanisms of memory loss in Aβ and tau mouse models
2005
[7] Uses of transposons with emphasis on Tn10
1991
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse
2001
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity
1999
Oxidation Proteomics: The Role of Thiol Modifications
2009
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
β-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or β-amyloid deposits
2006
Reduction of amyloid load and cerebral damage in transgenic mouse model of Alzheimer's disease by treatment with a β‐sheet breaker peptide
2002
Spermidine in health and disease
2018 StandoutScience
Reduced incidence of AD with NSAID but not H2receptor antagonists
2002
Modulation of β‐amyloid metabolism by non‐steroidal anti‐inflammatory drugs in neuronal cell cultures
2003
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
2005
Reduction of Aβ accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidylinositol kinase inhibitor wortmannin
2000
Apolipoprotein E ε4 allele, AD pathology, and the clinical expression of Alzheimer’s disease
2003
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Anti-Inflammatory Drug Therapy Alters β-Amyloid Processing and Deposition in an Animal Model of Alzheimer's Disease
2003
Microglial Activation and β-Amyloid Deposit Reduction Caused by a Nitric Oxide-Releasing Nonsteroidal Anti-Inflammatory Drug in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mice
2002
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial.
2003
Nonsteroidal anti-inflammatory drugs lower Aβ42 and change presenilin 1 conformation
2004
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
The phytochemical, EGCG , extends lifespan by reducing liver and kidney function damage and improving age‐associated inflammation and oxidative stress in healthy rats
2013
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
2006 Standout
Works of Bruce Teter being referenced
A Diet Enriched with the Omega-3 Fatty Acid Docosahexaenoic Acid Reduces Amyloid Burden in an Aged Alzheimer Mouse Model
2005
Ibuprofen Suppresses Interleukin-1β Induction of Pro-Amyloidogenic α1-Antichymotrypsin to Ameliorate β-Amyloid (Aβ) Pathology in Alzheimer's Models
2005
Methylation of the glial fibrillary acidic protein gene shows novel biphasic changes during brain development
1996
Age‐related increases in glial fibrillary acidic protein do not show proportionate changes in transcription rates or DNA methylation in the cerebral cortex and hippocampus of male rats
1994
Methylation of the rat glial fibrillary acidic protein gene shows tissue‐specific domains
1994
Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions
2005
Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice
2012
Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease
2006
Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer’s Disease
2008
Insulin-Degrading Enzyme as a Downstream Target of Insulin Receptor Signaling Cascade: Implications for Alzheimer's Disease Intervention
2004
Defective neuronal sprouting by human apolipoprotein E4 is a gain‐of‐negative function
2002
Estrogen (E2) and glucocorticoid (Gc) effects on microglia and Aβ clearance in vitro and in vivo
2001
Human Apolipoprotein E Isoform‐Specific Differences in Neuronal Sprouting in Organotypic Hippocampal Culture
1999
Docosahexaenoic Acid Protects from Dendritic Pathology in an Alzheimer's Disease Mouse Model
2004
Antibodies against β‐amyloid reduce aβ oligomers, glycogen synthase kinase‐3β activation and τ phosphorylation in vivo and in vitro
2005
Neuroplasticity in Alzheimer's disease
2002
Functional promoters created by the insertion of transposable element IS1
1986
Ibuprofen Suppresses Plaque Pathology and Inflammation in a Mouse Model for Alzheimer's Disease
2000
Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease.
1998
Transcriptional regulation of glial fibrillary acidic protein by corticosterone in rat astrocytes in vitro is influenced by the duration of time in culture and by astrocyte-neuron interactions.
1995