Citation Impact
Citing Papers
TOR Signaling in Growth and Metabolism
2006 Standout
Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis.
1996
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
Postnatal development and progression of renal dysplasia in cyclooxygenase-2 null mice
2000 StandoutNobel
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Molecular genetics of implantation in the mouse
1997
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice
2006 StandoutNobel
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
Molecular development of the kidney: A review of the results of gene disruption studies
1998
Inflammation and cancer
2002 StandoutNature
Renal pathology resulting from PGHS-2 gene ablation in DBA/B6 mice
2002
The role of cyclooxygenases in inflammation, cancer, and development
1999
Induction of Cyclooxygenase-2 and Prostaglandin F2αReceptor Expression by Interleukin-1β in Cultured Human Granulosa-Luteal Cells1
1997
Integrating the MAP kinase signal into the G1 phase cell cycle machinery
2000
Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta
1999
IL-6 Blockade Attenuates the Development of Murine Sclerodermatous Chronic Graft-Versus-Host Disease
2012
MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade
2016
Cyclooxygenase‐deficient Mice: A Summary of Their Characteristics and Susceptibilities to Inflammation and Carcinogenesis
1999
Host cyclooxygenase-2 modulates carcinoma growth
2000
Distribution and function of prostanoid receptors: studies from knockout mice
2000
The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure
2001
Roles of Prostanoids Revealed From Studies Using Mice Lacking Specific Prostanoid Receptors.
2000
Cyclooxygenase knockout mice
1999
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2
2000 StandoutNobel
Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial
2005 Standout
Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor
1999 StandoutNobel
Cyclooxygenase‐2 and its regulation in inflammation
1996
Multiple Female Reproductive Failures in Cyclooxygenase 2–Deficient Mice
1997
Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target
2007 Nobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Basic biology and clinical application of specific cyclooxygenase-2 inhibitors
2000
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
β2-Adrenergic Receptor-induced p38 MAPK Activation Is Mediated by Protein Kinase A Rather than by Gi or Gβγ in Adult Mouse Cardiomyocytes
2000 StandoutNobel
Cyclooxygenase-2 Inhibitors in Tumorigenesis (Part I)
1998
Design of selective inhibitors of cyclooxygenase-2 as nonulcerogenic anti-inflammatory agents
1998
Inhibition of T Cell Signaling by Mitogen-activated Protein Kinase-targeted Hematopoietic Tyrosine Phosphatase (HePTP)
1999
Cyclooxygenase inhibitors – current status and future prospects
2001
Developmental regulation of the growth plate
2003 StandoutNature
Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.
1997
Platelet Activation and Atherothrombosis
2007 Standout
Cyclooxygenase-2 (COX-2) and the kidney: current status and potential perspectives
1998
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor
2011 StandoutNobel
Cyclooxygenase-2: a target for the prevention and treatment of breast cancer.
2001
B-cell-derived lymphotoxin promotes castration-resistant prostate cancer
2010 Nature
Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition
2001 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes
2001
Prostaglandin E synthase
2002
Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways
2000
An E-box Region within the Prostaglandin Endoperoxide Synthase-2 (PGS-2) Promoter Is Required for Transcription in Rat Ovarian Granulosa Cells
1996
Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells
1998 Standout
Cyclooxygenase-1-Coupled Prostaglandin Biosynthesis Constitutes an Essential Prerequisite for Skin Repair
2003
Cyclo-Oxygenase Isoenzymes
1997
Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production.
1997
Inflammation and cancer: back to Virchow?
2001 Standout
Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
1996 Standout
Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo
2001
Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: Implications for gastrointestinal toxicity
1998
Sustained Induction of Prostaglandin Endoperoxide Synthase-2 by Seizures in Hippocampus
1996
Obesity is induced in mice heterozygous for cyclooxygenase-2
2001
Anti-inflammatory drugs and their mechanism of action
1998 Nobel
Dissociation of Basal Turnover and Cytokine-Induced Transcript Stabilization of the Human Cyclooxygenase-2 mRNA by Mutagenesis of the 3′-Untranslated Region
1998
What We Talk About When We Talk About Fat
2014 Standout
Cyclooxygenase-2 Inhibitors in Tumorigenesis (Part II)
1998
Insight into prostaglandin, leukotriene, and other eicosanoid functions using mice with targeted gene disruptions☆
1999
Tumorigenic Transformation of Immortalized ECV Endothelial Cells by Cyclooxygenase-1 Overexpression
1997
The basics of epithelial-mesenchymal transition
2009 Standout
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
The Coxibs, Selective Inhibitors of Cyclooxygenase-2
2001
Specificity and mechanism of action of some commonly used protein kinase inhibitors
2000 Standout
Allergic lung responses are increased in prostaglandin H synthase–deficient mice
1999
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Endocannabinoid-Mediated Control of Synaptic Transmission
2009
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs
1999
Roles of PPARs in health and disease
2000 StandoutNature
Role of cytosolic phospholipase A2 in allergic response and parturition
1997 Nature
Genetic model of selective COX2 inhibition reveals novel heterodimer signaling
2006
Butyrate enhancement of inteleukin-1β production via activation of oxidative stress pathways in lipopolysaccharide-stimulated THP-1 cells
2011
Cyclo-Oxygenase-2 Inhibitors
2000
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin
2001
Effects of Specific Inhibition of Cyclooxygenase-2 on Sodium Balance, Hemodynamics, and Vasoactive Eicosanoids
1999
Induction of cutaneousgraft-versus-hostdisease by local injection of unprimed T cells
1991
Disruption of Cyclooxygenase Genes in Mice
1996
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Cyclooxygenase-2–selective inhibitors impair glomerulogenesis and renal cortical development
2000
Failure of Parturition in Mice Lacking the Prostaglandin F Receptor
1997 Science
Generation and reproductive phenotypes of mice lacking estrogen receptor β
1998 StandoutNobel
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
A genetically clamped renin transgene for the induction of hypertension
2002 StandoutNobel
Role of Prostacyclin in the Cardiovascular Response to Thromboxane A 2
2002 StandoutScience
CYCLOOXYGENASES 1 AND 2
1998 StandoutNobel
Cyclooxygenase in biology and disease
1998 Standout
1997 StandoutNobel
Cyclooxygenase-1 and an alternatively spliced mRNA in the rat stomach: effects of aging and ulcers
2000
Up-regulation of the chondrogenicSox9gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway
2000
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
Cyclooxygenases, Thromboxane, and Atherosclerosis
2005
The Pharmacology of the Ductus Arteriosus
1998
Molecular Cues to Implantation
2004
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Prostaglandins and Inflammation
2011 Standout
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors
1999
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
Prostaglandin endoperoxide synthase: why two isoforms?
1996
4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2
2000
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes
2001
Works of Bruce Jaffee being referenced
Inhibition of Mitogen-Activated Protein Kinase Kinase Blocks T Cell Proliferation But Does Not Induce or Prevent Anergy
1998
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
1995 Nature
Inhibition of MAP Kinase Kinase (MEK) Results in an Anti-inflammatory Response in Vivo
2000
A Selective Small Molecule IκB Kinase β Inhibitor Blocks Nuclear Factor κB-Mediated Inflammatory Responses in Human Fibroblast-Like Synoviocytes, Chondrocytes, and Mast Cells
2006
Macrocyclic hydroxamate inhibitors of matrix metalloproteinases and TNF-α production
1999
The effect of immunomodulating drugs on adjuvant-induced arthritis in Lewis rats
1989
Chronic graft-versus-host disease as a model for scleroderma
1985
Chronic graft-versus-host disease (GVHD) as a model for scleroderma
1983
Design and Synthesis of Cyclic Inhibitors of Matrix Metalloproteinases and TNF-α Production
1998