Citation Impact
Citing Papers
Signal transduction and regulation in smooth muscle
1994 StandoutNature
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Origins of catalysis by computationally designed retroaldolase enzymes
2010 StandoutNobel
Identification of a New Urate and High Affinity Nicotinate Transporter, hOAT10 (SLC22A13)
2008
Cell mechanics and the cytoskeleton
2010 StandoutNature
Allosteric Binding of Nucleoside Triphosphates to RNA Polymerase Regulates Transcription Elongation
2001
Structural Basis of Transcription
2004 StandoutNobel
Kinetic characterization of the polymerase and exonuclease activities of the gene 43 protein of bacteriophage T4
1992
Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders
2011
Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity
1988
Substrate Binding by Human Apurinic/Apyrimidinic Endonuclease Indicates a Briggs-Haldane Mechanism
1997
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Hydrophobic interactions via mutants of Escherichia coli dihydrofolate reductase: separation of binding and catalysis
1989
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity
1995
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Building a Replisome from Interacting Pieces
1999 StandoutNobel
Interaction of Escherichia coli DNA polymerase I with azidoDNA and fluorescent DNA probes: identification of protein-DNA contacts
1990
Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction
1991
Three-dimensional structure of myosin subfragment-1: a molecular motor
1993 StandoutScience
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
2009 StandoutNature
MutS and MutL Activate DNA Helicase II in a Mismatch-dependent Manner
1998 StandoutNobel
Mitochondria: In Sickness and in Health
2012 Standout
Kinetic mechanism of DNA polymerase I(Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant
1991
DNA Structure and Aspartate 276 Influence Nucleotide Binding to Human DNA Polymerase β
2001
Kinetic mechanism of DNA polymerase I (Klenow)
1987
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
Bis‐Azobenzene Crosslinkers for Photocontrol of Peptide Structure
2011
The receptors and cells for mammalian taste
2006 StandoutNature
Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant
1991
Cooperative self-assembly: producing synthetic polymers with precise and concise primary structures
2012 StandoutNobel
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
CASK Functions as a Mg2+-Independent Neurexin Kinase
2008 StandoutNobel
Global Kinetic Explorer: A new computer program for dynamic simulation and fitting of kinetic data
2008
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
2008
Nucleation–elongation: a mechanism for cooperative supramolecular polymerization
2003
Leptin and the regulation of body weight in mammals
1998 StandoutNature
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
Inactivation of DNA polymerase I (Klenow fragment) by adenosine 2',3'-epoxide 5'-triphosphate: evidence for the formation of a tight-binding inhibitor
1989
Inhibition of the initiation of HIV-1 reverse transcription by AZT : Comparison with elongation
2000
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
DNA Polymerases: Structural Diversity and Common Mechanisms
1999 StandoutNobel
The human taste receptor hTAS2R14 responds to a variety of different bitter compounds
2004
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Regulatory effects of ATP and luciferin on firefly luciferase activity
1995
Controlled Clinical Trial of Dichloroacetate for Treatment of Congenital Lactic Acidosis in Children
2006
Stereochemistry of RNA Cleavage by the Tetrahymena Ribozyme and Evidence that the Chemical Step Is Not Rate-Limiting
1989 StandoutScienceNobel
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients
1997 StandoutNobel
Comparison of the myosin and actomyosin ATPase mechanisms of the four types of vertebrate muscles
1980
Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase.
1994 StandoutNobel
Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli.
1990 StandoutNobel
In Situ Click Chemistry: Enzyme Inhibitors Made to Their Own Specifications
2004 StandoutNobel
Crystallization of myosin subfragment 1.
1984
The equivalence of phosphate oxygens for exchange and the hydrolysis characteristics revealed by the distribution of [18O]Pi species formed by myosin and actomyosin ATPase.
1980 StandoutNobel
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
1992 StandoutScience
Quality Control by DNA Repair
1999 StandoutScienceNobel
Structure And Evolution Of Calcium-Modulated Protein
1980
Studies on the chymotryptic digestion of myosin. Effects of divalent cations on proteolytic susceptibility
1977
Human immunodeficiency virus reverse transcriptase. A kinetic analysis of RNA-dependent and DNA-dependent DNA polymerization.
1993
Multisubstrate adduct inhibitors of glycinamide ribonucleotide transformylase: Synthetic and enzyme-assembled.
1991
Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase.
1993 StandoutNobel
Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins.
1988 StandoutNobel
[61] Rapid kinetic analysis of mechanochemical adenosinetriphosphatases
1986
Chemical arrows for enzymatic targets
1997
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
DNA specificity enhanced by sequential binding of protein monomers
1999
Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases
2005 StandoutNobel
The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments
1998
Gout
2021 Standout
Mechanism of oxygen exchange in actin-activated hydrolysis of adenosine triphosphate by myosin subfragment 1
1977
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
Comparative studies of oxygen exchange catalyzed by myosin, heavy meromyosin, and subfragment 1. Evidence that the γ-phosphoryl group of adenosine triphosphate binds to myosin in the region of the (subfragmental 1)-(subfragment 2) hinge
1977
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Structural and kinetic analysis of a channel-impaired mutant of tryptophan synthase.
1994
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
In Situ Selection of Lead Compounds by Click Chemistry: Target-Guided Optimization of Acetylcholinesterase Inhibitors
2005 StandoutNobel
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli.
1992
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Serine modulates substrate channeling in tryptophan synthase. A novel intersubunit triggering mechanism
1991
Kinetic and Catalytic Mechanisms of Protein Kinases
2001
Inhibition of the Initiation of HIV-1 Reverse Transcription by 3′-Azido-3′-deoxythymidine
2000
Oxygen exchange by single-headed myosin. Further support for the hypothesis that the active site of myosin is near the (subfragment 1)-(subfragment 2) hinge.
1978
Multiple RNA Polymerase Conformations and GreA: Control of the Fidelity of Transcription
1993 Science
Kinetic Measurement of the Step Size of DNA Unwinding by Escherichia coli UvrD Helicase
1997 Science
Packing analysis of crystalline myosin subfragment-1
1985
Mechanism and fidelity of HIV reverse transcriptase.
1992
Isolation and distribution of myosin isoenzymes in chicken pectoralis muscle
1981
Protein structural domains in the Caenorhabditis elegans unc-54 myosin heavy chain gene are not separated by introns.
1983 StandoutNobel
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
1997 StandoutNobel
Calmodulin Plays a Pivotal Role in Cellular Regulation
1980 StandoutScience
Mechanism of Actomyosin Atpase and the Problem of Muscle Contractio
1979
Homogeneity of myosin subfragments by equilibrium centrifugation
1981
Works of Bruce A. Barshop being referenced
A mutation in adenylosuccinate lyase associated with mental retardation and autistic features
1992
Mitochondrial DNA polymerase ? deficiency and mtDNA depletion in a child with Alpers' syndrome
1999
Nerve conduction changes in patients with mitochondrial diseases treated with dichloroacetate
2001
Chronic treatment of mitochondrial disease patients with dichloroacetate
2004
Excretion of hippuric acid during sodium benzoate therapy in patients with hyperglycinaemia or hyperammonaemia
1988
Metabolomics Identifies Perturbations in Human Disorders of Propionate Metabolism
2007
Multiple organic anion transporters contribute to net renal excretion of uric acid
2008
Luminescent immobilized enzyme test systems for inorganic pyrophosphate: Assays using firefly luciferase and nicotinamide-mononucleotide adenylyl transferase or adenosine-5′-triphosphate sulfurylase
1991
Effect of DTNB light chain on the interaction of vertebrate skeletal myosin with actin
1975 Nature
Analysis of numerical methods for computer simulation of kinetic processes: Development of KINSIM—A flexible, portable system
1983