Standout Papers
- An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. (1990)
- Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. (1992)
Citation Impact
Citing Papers
Human Hypertension Caused by Mutations in WNK Kinases
2001 StandoutScience
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
Arresting a Transient Receptor Potential (TRP) Channel
2010 StandoutNobel
Prevention of Type 2 Diabetes Mellitus Through Inhibition of the Renin-Angiotensin System
2004
Insertion/deletion polymorphism in the angiotensin-l-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy
1995
Variations of Human Adrenomedullin Gene and Its Relation to Cardiovascular Diseases
2003
[18] Peptidyl dipeptidase A: Angiotensin I-converting enzyme
1995
Angiotensin-Converting Enzyme Gene Polymorphism Determines the Antiproteinuric and Systemic Hemodynamic Effect of Enalapril in Patients with Proteinuric Renal Disease
1998
Contribution of gene polymorphisms in the renin-angiotensin system to macroangiopathy in patients with diabetic nephropathy
2001
Genetic associations with human longevity at the APOE and ACE loci
1994 Standout
A Prospective Evaluation of an Angiotensin-Converting–Enzyme Gene Polymorphism and the Risk of Ischemic Heart Disease
1995
Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline.
1996
Many little things: one geneticist's view of complex diseases
2005 StandoutNobel
Minireview: Computer Simulations of Blood Pressure Regulation by the Renin-Angiotensin System
2003 StandoutNobel
Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept
2011
Association between a Deletion Polymorphism of the Angiotensin-Converting-Enzyme Gene and Left Ventricular Hypertrophy
1994
Molecular basis of human hypertension: Role of angiotensinogen
1992 Standout
Functional consequences of angiotensin-converting enzyme gene polymorphism on N-acetyl-Ser-Asp-Lys-Pro degradation and angiotensin II production
2002
Angiotensin converting enzyme gene polymorphisms and renal disease
1998
Deletion polymorphism in angiotensin-converting enzyme gene associated with parental history of myocardial infarction
1993
Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy.
1995
A deletion polymorphism in the angiotensin converting enzyme gene is not associated with coronary heart disease in an Austrian population
1995
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway
1999 StandoutNobel
Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
1992 StandoutNature
Role of the N-terminal Catalytic Domain of Angiotensin-converting Enzyme Investigated by Targeted Inactivation in Mice
2004 StandoutNobel
Association analyses of the polymorphisms of angiotensin-converting enzyme and angiotensinogen genes with diabetic nephropathy in Japanese non-insulin-dependent diabetics
1996
UK Prospective Diabetes Study (UKPDS) 14: association of angiotensin-converting enzyme insertion/deletion polymorphism with myocardial infarction in NIDDM
1995 StandoutNobel
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy
1996
Putative roles of kinin receptors in the therapeutic effects of angiotensin 1-converting enzyme inhibitors in diabetes mellitus
2004
Forging a signature of in vivo senescence
2015
U.K. Prospective Diabetes Study XV: Relationship of renin-angiotensin system gene polymorphisms with microalbuminuria in NIDDM
1995 StandoutNobel
The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice.
1997 StandoutNobel
The angiotensin‐converting enzyme (ACE) genetic polymorphism: its relationship with plasma ACE level and myocardial infarction
1994
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
A genetic study of angiotensin I-converting enzyme levels in human semen
1995
Polymorphisms of the apolipoprotein and angiotensin converting enzyme genes in young North Karelian patients with coronary heart disease
1994
Angiotensin I-Converting Enzyme Gene Polymorphism and Acute Response to Captopril in Essential Hypertension
1997
Measured Haplotype Analysis of the Angiotensin-I Converting Enzyme Gene
1998 StandoutNobel
Effect of the Insertion/Deletion Polymorphism of the Angiotensin-Converting Enzyme Gene on Response to Angiotensin-Converting Enzyme Inhibitors in Patients with Heart Failure
1998
Angiotensin-converting enzyme 2 protects from severe acute lung failure
2005 StandoutNature
Glycosylation in health and disease
2019
Cosegregation of blood pressure with angiotensin converting enzyme and atrial natriuretic peptide receptor genes using Dahl salt–sensitive rats
1992
Sex-specific genetic architecture of human disease
2008
Male–female differences in fertility and blood pressure in ACE-deficient mice
1995 StandoutNatureNobel
Importance of quantitative genetic variations in the etiology of hypertension
2000 StandoutNobel
Linkage of the Angiotensinogen Gene to Essential Hypertension
1994
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Quantification of β-galactosidase activity after non-viral transfection in vivo
2003
Insertion /deletion (I/D) polymorphism at the locus for angiotensin I‐converting enzyme and parental history of myocardial infarction
1993
Angiotensin Converting Enzyme Gene Polymorphism Is Not Related to Essential Hypertension in a Greek Population
1996
Homeostasis in Mice with Genetically Decreased Angiotensinogen Is Primarily by an Increased Number of Renin-producing Cells
1999 StandoutNobel
A shortcut to the lysosome: The mannose-6-phosphate-independent pathway
2012
Atherosclerosis
2000 StandoutNature
Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension
1992
An angiotensin-converting enzyme gene variant is associated with acute myocardial infarction in women but not in men
1995
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Significance of angiotensin I-converting enzyme and angiotensin II type 1 receptor gene polymorphisms as risk factors for coronary heart disease
1996
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Human genetics, animal models and computer simulations for studying hypertension☆
2004 StandoutNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Prognostic Value of Angiotensin-I Converting Enzyme I/D Polymorphism for Nephropathy in Type 1 Diabetes Mellitus
2001
Angiotensin Converting Enzyme Insertion/Deletion Polymorphism Is Associated with Susceptibility and Outcome in Acute Respiratory Distress Syndrome
2002
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Molecular Genetics of Human Blood Pressure Variation
1996 Science
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Genetic Models of Human Vascular Disease
1995 StandoutNobel
Angiotensin-Converting Enzyme Gene Polymorphism Has No Influence on the Circulating Renin-Angiotensin-Aldosterone System or Blood Pressure in Normotensive Subjects
1995
Genetic Linkage of the ACE Gene to Plasma Angiotensin-Converting Enzyme Activity but Not to Blood Pressure
1995
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males
2007 StandoutNobel
Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Modulates the Human In Vivo Metabolism of Bradykinin
2000
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
2001 StandoutNobel
Gene Polymorphism but not Catalytic Activity of Angiotensin I–Converting Enzyme Is Associated With Coronary Artery Disease and Myocardial Infarction in Low-Risk Patients
1995
Plasma level and gene polymorphism of angiotensin-converting enzyme in relation to myocardial infarction.
1994
The angiotensin I converting enzyme gene and predisposition to high blood pressure.
1993
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
BIOLOGICAL FUNCTIONS OF ANGIOTENSIN AND ITS RECEPTORS
1997
Angiotensin I-converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes
1993
Angiotensin-Converting Enzyme Gene and Atherosclerosis
1997 StandoutNobel
Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction.
1995
Modifier genes for hypertrophic cardiomyopathy
2002
African origin of human-specific polymorphic Alu insertions.
1994
A Mouse View of Hypertension
1997 StandoutNobel
Evidence for a Gene Influencing Blood Pressure on Chromosome 17
2000
Angiotensin I-Converting Enzyme Gene Polymorphism Is Associated With Myocardial Infarction, but Not With Retinopathy or Nephropathy, in NIDDM
1995
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner
1998 StandoutNobel
Genetic Dissection of Complex Traits
1994 StandoutScience
Angiotensin-Converting Enzyme Gene Polymorphism Is Associated With Myocardial Infarction but Not With Development of Coronary Stenosis
1995
Angiotensin-converting enzyme and male fertility
1998 StandoutNobel
Genetic control of blood pressure and the angiotensinogen locus.
1995 StandoutNobel
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with serum ACE concentration and increased risk for CAD in the Japanese.
1994
Angiotensin-Converting Enzyme Gene Mutations, Blood Pressures, and Cardiovascular Homeostasis
1997 StandoutNobel
Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.
1994 StandoutNobel
Pharmacogenetic Interactions Between β-Blocker Therapy and the Angiotensin-Converting Enzyme Deletion Polymorphism in Patients With Congestive Heart Failure
2001
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus.
1994
Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
1996 StandoutScience
Analysis of phenotypic consequences of renin gene polymorphism in Lyon rats
1997
A DNA Variant at the Angiotensin-Converting Enzyme Gene Locus Associates With Coronary Artery Disease in the Caerphilly Heart Study
1995
Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.
1995 StandoutNobel
A Meta-analysis of the Association of the Deletion Allele of the Angiotensin-Converting Enzyme Gene With Myocardial Infarction
1996
High Plasma Level ofN-Acetyl-Seryl-Aspartyl-Lysyl-Proline
1997
Molecular phenotyping for analyzing subtle genetic effects in mice: Application to an angiotensinogen gene titration
2002 StandoutNobel
Works of Brigitte Rigat being referenced
An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.
1990 Standout
Structure of the GM2A Gene: Identification of an Exon 2 Nonsense Mutation and a Naturally Occurring Transcript with an In-Frame Deletion of Exon 2
1999
Sib pair linkage analysis of renin gene haplotypes in human essential hypertension
1992
PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)
1992
Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β‐Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry
2008
Similar frequencies of renin gene restriction fragment length polymorphisms in hypertensive and normotensive subjects.
1990
Induction of endogenous β-galactosidase by ionizing radiation complicates the analysis of p53-LacZ transgenic mice
2001
Two Mechanisms for the Recapture of Extracellular GM2Activator Protein: Evidence for a Major Secretory Form of the Protein
1997
Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.
1992 Standout